Outpatient percutaneous treatment of deep venous malformations using pure ethanol at low doses under local anesthesia
Main Author: | |
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Publication Date: | 2010 |
Other Authors: | , , , |
Format: | Article |
Language: | eng |
Source: | Clinics |
Download full: | https://www.revistas.usp.br/clinics/article/view/18538 |
Summary: | INTRODUCTION: Venous malformations are the most frequent vascular malformation. Deep venous malformations are located in subcutaneous tissue or in the muscles. Percutaneous sclerotherapy is the treatment of choice, and the use of ethanol at low doses has not yet been described. OBJECTIVE: To analyze the results of treating Deep venous malformations patients with low doses of ethanol. METHODS: Thirty-nine patients treated between July 1995 and June 2007 were followed up prospectively over a median period of 18 months. Twenty-nine were female (74.4%) and 10 were male (25.6%), with ages ranging from 11 to 59 years (median of 24 years). All of the lesions affected limbs, and the main symptom reported was pain (97.4%). Each patient underwent fortnightly alcohol application sessions under local anesthesia on an outpatient basis. The lesions were classified into three groups according to size using nuclear magnetic resonance imaging: small, up to 3 cm (4 patients); medium, between 3 and 15 cm (27 patients); and large, greater than 15 cm (8 patients). RESULTS: The symptoms completely disappeared in 14 patients (35.9%) and improved in 24 (61.5%). The lesion size reduced to zero in 6 patients (15.4%) and decreased in 32 (82%). The median number of sessions was 7. There were no complications in 32 patients (82%), while 3 presented local paresthesia (7.7%), 2 superficial trombophlebites (5.1%), 1 skin ulcer (2.6%), and 1 case of hyperpigmentation (2.6%). CONCLUSION: Outpatient treatment for Deep venous malformations patients using ethanol at low doses was effective, with a low complication rate. |
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Outpatient percutaneous treatment of deep venous malformations using pure ethanol at low doses under local anesthesia Venous malformationsPercutaneousSclerotherapyEthanolLocal anesthesia INTRODUCTION: Venous malformations are the most frequent vascular malformation. Deep venous malformations are located in subcutaneous tissue or in the muscles. Percutaneous sclerotherapy is the treatment of choice, and the use of ethanol at low doses has not yet been described. OBJECTIVE: To analyze the results of treating Deep venous malformations patients with low doses of ethanol. METHODS: Thirty-nine patients treated between July 1995 and June 2007 were followed up prospectively over a median period of 18 months. Twenty-nine were female (74.4%) and 10 were male (25.6%), with ages ranging from 11 to 59 years (median of 24 years). All of the lesions affected limbs, and the main symptom reported was pain (97.4%). Each patient underwent fortnightly alcohol application sessions under local anesthesia on an outpatient basis. The lesions were classified into three groups according to size using nuclear magnetic resonance imaging: small, up to 3 cm (4 patients); medium, between 3 and 15 cm (27 patients); and large, greater than 15 cm (8 patients). RESULTS: The symptoms completely disappeared in 14 patients (35.9%) and improved in 24 (61.5%). The lesion size reduced to zero in 6 patients (15.4%) and decreased in 32 (82%). The median number of sessions was 7. There were no complications in 32 patients (82%), while 3 presented local paresthesia (7.7%), 2 superficial trombophlebites (5.1%), 1 skin ulcer (2.6%), and 1 case of hyperpigmentation (2.6%). CONCLUSION: Outpatient treatment for Deep venous malformations patients using ethanol at low doses was effective, with a low complication rate. Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo2010-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/clinics/article/view/1853810.1590/S1807-59322010000900004Clinics; v. 65 n. 9 (2010); 837-840 Clinics; Vol. 65 Núm. 9 (2010); 837-840 Clinics; Vol. 65 No. 9 (2010); 837-840 1980-53221807-5932reponame:Clinicsinstname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/clinics/article/view/18538/20601Orlando, José LuizCaldas, Jose Guilherme Mendes PereiraCampos, Heloisa Galvão do AmaralNishinari, KenjiWolosker, Nelsoninfo:eu-repo/semantics/openAccess2012-05-23T11:31:22Zoai:revistas.usp.br:article/18538Revistahttps://www.revistas.usp.br/clinicsPUBhttps://www.revistas.usp.br/clinics/oai||clinics@hc.fm.usp.br1980-53221807-5932opendoar:2012-05-23T11:31:22Clinics - Universidade de São Paulo (USP)false |
dc.title.none.fl_str_mv |
Outpatient percutaneous treatment of deep venous malformations using pure ethanol at low doses under local anesthesia |
title |
Outpatient percutaneous treatment of deep venous malformations using pure ethanol at low doses under local anesthesia |
spellingShingle |
Outpatient percutaneous treatment of deep venous malformations using pure ethanol at low doses under local anesthesia Orlando, José Luiz Venous malformations Percutaneous Sclerotherapy Ethanol Local anesthesia |
title_short |
Outpatient percutaneous treatment of deep venous malformations using pure ethanol at low doses under local anesthesia |
title_full |
Outpatient percutaneous treatment of deep venous malformations using pure ethanol at low doses under local anesthesia |
title_fullStr |
Outpatient percutaneous treatment of deep venous malformations using pure ethanol at low doses under local anesthesia |
title_full_unstemmed |
Outpatient percutaneous treatment of deep venous malformations using pure ethanol at low doses under local anesthesia |
title_sort |
Outpatient percutaneous treatment of deep venous malformations using pure ethanol at low doses under local anesthesia |
author |
Orlando, José Luiz |
author_facet |
Orlando, José Luiz Caldas, Jose Guilherme Mendes Pereira Campos, Heloisa Galvão do Amaral Nishinari, Kenji Wolosker, Nelson |
author_role |
author |
author2 |
Caldas, Jose Guilherme Mendes Pereira Campos, Heloisa Galvão do Amaral Nishinari, Kenji Wolosker, Nelson |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Orlando, José Luiz Caldas, Jose Guilherme Mendes Pereira Campos, Heloisa Galvão do Amaral Nishinari, Kenji Wolosker, Nelson |
dc.subject.por.fl_str_mv |
Venous malformations Percutaneous Sclerotherapy Ethanol Local anesthesia |
topic |
Venous malformations Percutaneous Sclerotherapy Ethanol Local anesthesia |
description |
INTRODUCTION: Venous malformations are the most frequent vascular malformation. Deep venous malformations are located in subcutaneous tissue or in the muscles. Percutaneous sclerotherapy is the treatment of choice, and the use of ethanol at low doses has not yet been described. OBJECTIVE: To analyze the results of treating Deep venous malformations patients with low doses of ethanol. METHODS: Thirty-nine patients treated between July 1995 and June 2007 were followed up prospectively over a median period of 18 months. Twenty-nine were female (74.4%) and 10 were male (25.6%), with ages ranging from 11 to 59 years (median of 24 years). All of the lesions affected limbs, and the main symptom reported was pain (97.4%). Each patient underwent fortnightly alcohol application sessions under local anesthesia on an outpatient basis. The lesions were classified into three groups according to size using nuclear magnetic resonance imaging: small, up to 3 cm (4 patients); medium, between 3 and 15 cm (27 patients); and large, greater than 15 cm (8 patients). RESULTS: The symptoms completely disappeared in 14 patients (35.9%) and improved in 24 (61.5%). The lesion size reduced to zero in 6 patients (15.4%) and decreased in 32 (82%). The median number of sessions was 7. There were no complications in 32 patients (82%), while 3 presented local paresthesia (7.7%), 2 superficial trombophlebites (5.1%), 1 skin ulcer (2.6%), and 1 case of hyperpigmentation (2.6%). CONCLUSION: Outpatient treatment for Deep venous malformations patients using ethanol at low doses was effective, with a low complication rate. |
publishDate |
2010 |
dc.date.none.fl_str_mv |
2010-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/clinics/article/view/18538 10.1590/S1807-59322010000900004 |
url |
https://www.revistas.usp.br/clinics/article/view/18538 |
identifier_str_mv |
10.1590/S1807-59322010000900004 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/clinics/article/view/18538/20601 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo |
publisher.none.fl_str_mv |
Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo |
dc.source.none.fl_str_mv |
Clinics; v. 65 n. 9 (2010); 837-840 Clinics; Vol. 65 Núm. 9 (2010); 837-840 Clinics; Vol. 65 No. 9 (2010); 837-840 1980-5322 1807-5932 reponame:Clinics instname:Universidade de São Paulo (USP) instacron:USP |
instname_str |
Universidade de São Paulo (USP) |
instacron_str |
USP |
institution |
USP |
reponame_str |
Clinics |
collection |
Clinics |
repository.name.fl_str_mv |
Clinics - Universidade de São Paulo (USP) |
repository.mail.fl_str_mv |
||clinics@hc.fm.usp.br |
_version_ |
1787713171639762944 |