Lack of reliable clinical predictors to identify obstructive sleep apnea in patients with hypertrophic cardiomyopathy
Autor(a) principal: | |
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Data de Publicação: | 2013 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Clinics |
Texto Completo: | https://www.revistas.usp.br/clinics/article/view/76930 |
Resumo: | OBJECTIVE: Obstructive sleep apnea is common among patients with hypertrophic cardiomyopathy and may contribute to poor cardiovascular outcomes. However, obstructive sleep apnea is largely unrecognized in this population. We sought to identify the clinical predictors of obstructive sleep apnea among patients with hypertrophic cardiomyopathy. METHODS: Consecutive patients with hypertrophic cardiomyopathy were recruited from a tertiary University Hospital and were evaluated using validated sleep questionnaires (Berlin and Epworth) and overnight portable monitoring. Ninety patients (males, 51%; age, 46±15 years; body mass index, 26.6±4.9 kg/m2) were included, and obstructive sleep apnea (respiratory disturbance index ≥15 events/h) was present in 37 patients (41%). RESULTS: Compared with the patients without obstructive sleep apnea, patients with obstructive sleep apnea were older and had higher body mass index, larger waist circumference, larger neck circumference, and higher prevalence of atrial fibrillation. Excessive daytime sleepiness (Epworth scale) was low and similar in the patients with and without obstructive sleep apnea, respectively. The only predictors of obstructive sleep apnea (using a logistic regression analysis) were age ≥45 years (odds ratio [OR], 4.46; 95% confidence interval [CI 95%], 1.47-13.54; p = 0.008) and the presence of atrial fibrillation [OR, 5.37; CI 95%, 1.43-20.12; p = 0.013]. CONCLUSION: Consistent clinical predictors of obstructive sleep apnea are lacking for patients with hypertrophic cardiomyopathy, which suggests that objective sleep evaluations should be considered in this population, particularly among elderly patients with atrial fibrillation. |
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Clinics |
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Lack of reliable clinical predictors to identify obstructive sleep apnea in patients with hypertrophic cardiomyopathyOBJECTIVE: Obstructive sleep apnea is common among patients with hypertrophic cardiomyopathy and may contribute to poor cardiovascular outcomes. However, obstructive sleep apnea is largely unrecognized in this population. We sought to identify the clinical predictors of obstructive sleep apnea among patients with hypertrophic cardiomyopathy. METHODS: Consecutive patients with hypertrophic cardiomyopathy were recruited from a tertiary University Hospital and were evaluated using validated sleep questionnaires (Berlin and Epworth) and overnight portable monitoring. Ninety patients (males, 51%; age, 46±15 years; body mass index, 26.6±4.9 kg/m2) were included, and obstructive sleep apnea (respiratory disturbance index ≥15 events/h) was present in 37 patients (41%). RESULTS: Compared with the patients without obstructive sleep apnea, patients with obstructive sleep apnea were older and had higher body mass index, larger waist circumference, larger neck circumference, and higher prevalence of atrial fibrillation. Excessive daytime sleepiness (Epworth scale) was low and similar in the patients with and without obstructive sleep apnea, respectively. The only predictors of obstructive sleep apnea (using a logistic regression analysis) were age ≥45 years (odds ratio [OR], 4.46; 95% confidence interval [CI 95%], 1.47-13.54; p = 0.008) and the presence of atrial fibrillation [OR, 5.37; CI 95%, 1.43-20.12; p = 0.013]. CONCLUSION: Consistent clinical predictors of obstructive sleep apnea are lacking for patients with hypertrophic cardiomyopathy, which suggests that objective sleep evaluations should be considered in this population, particularly among elderly patients with atrial fibrillation.Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo2013-07-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/clinics/article/view/7693010.1590/clin.v68i7.76930Clinics; Vol. 68 No. 7 (2013); 992-996Clinics; v. 68 n. 7 (2013); 992-996Clinics; Vol. 68 Núm. 7 (2013); 992-9961980-53221807-5932reponame:Clinicsinstname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/clinics/article/view/76930/80791Nerbass, Flavia B.Pedrosa, Rodrigo P.Genta, Pedro R.Antunes, Murillo O.Arteaga-Fernandez, EdmundoDrager, Luciano F.Lorenzi-Filho, Geraldoinfo:eu-repo/semantics/openAccess2014-03-24T11:50:37Zoai:revistas.usp.br:article/76930Revistahttps://www.revistas.usp.br/clinicsPUBhttps://www.revistas.usp.br/clinics/oai||clinics@hc.fm.usp.br1980-53221807-5932opendoar:2014-03-24T11:50:37Clinics - Universidade de São Paulo (USP)false |
dc.title.none.fl_str_mv |
Lack of reliable clinical predictors to identify obstructive sleep apnea in patients with hypertrophic cardiomyopathy |
title |
Lack of reliable clinical predictors to identify obstructive sleep apnea in patients with hypertrophic cardiomyopathy |
spellingShingle |
Lack of reliable clinical predictors to identify obstructive sleep apnea in patients with hypertrophic cardiomyopathy Nerbass, Flavia B. |
title_short |
Lack of reliable clinical predictors to identify obstructive sleep apnea in patients with hypertrophic cardiomyopathy |
title_full |
Lack of reliable clinical predictors to identify obstructive sleep apnea in patients with hypertrophic cardiomyopathy |
title_fullStr |
Lack of reliable clinical predictors to identify obstructive sleep apnea in patients with hypertrophic cardiomyopathy |
title_full_unstemmed |
Lack of reliable clinical predictors to identify obstructive sleep apnea in patients with hypertrophic cardiomyopathy |
title_sort |
Lack of reliable clinical predictors to identify obstructive sleep apnea in patients with hypertrophic cardiomyopathy |
author |
Nerbass, Flavia B. |
author_facet |
Nerbass, Flavia B. Pedrosa, Rodrigo P. Genta, Pedro R. Antunes, Murillo O. Arteaga-Fernandez, Edmundo Drager, Luciano F. Lorenzi-Filho, Geraldo |
author_role |
author |
author2 |
Pedrosa, Rodrigo P. Genta, Pedro R. Antunes, Murillo O. Arteaga-Fernandez, Edmundo Drager, Luciano F. Lorenzi-Filho, Geraldo |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Nerbass, Flavia B. Pedrosa, Rodrigo P. Genta, Pedro R. Antunes, Murillo O. Arteaga-Fernandez, Edmundo Drager, Luciano F. Lorenzi-Filho, Geraldo |
description |
OBJECTIVE: Obstructive sleep apnea is common among patients with hypertrophic cardiomyopathy and may contribute to poor cardiovascular outcomes. However, obstructive sleep apnea is largely unrecognized in this population. We sought to identify the clinical predictors of obstructive sleep apnea among patients with hypertrophic cardiomyopathy. METHODS: Consecutive patients with hypertrophic cardiomyopathy were recruited from a tertiary University Hospital and were evaluated using validated sleep questionnaires (Berlin and Epworth) and overnight portable monitoring. Ninety patients (males, 51%; age, 46±15 years; body mass index, 26.6±4.9 kg/m2) were included, and obstructive sleep apnea (respiratory disturbance index ≥15 events/h) was present in 37 patients (41%). RESULTS: Compared with the patients without obstructive sleep apnea, patients with obstructive sleep apnea were older and had higher body mass index, larger waist circumference, larger neck circumference, and higher prevalence of atrial fibrillation. Excessive daytime sleepiness (Epworth scale) was low and similar in the patients with and without obstructive sleep apnea, respectively. The only predictors of obstructive sleep apnea (using a logistic regression analysis) were age ≥45 years (odds ratio [OR], 4.46; 95% confidence interval [CI 95%], 1.47-13.54; p = 0.008) and the presence of atrial fibrillation [OR, 5.37; CI 95%, 1.43-20.12; p = 0.013]. CONCLUSION: Consistent clinical predictors of obstructive sleep apnea are lacking for patients with hypertrophic cardiomyopathy, which suggests that objective sleep evaluations should be considered in this population, particularly among elderly patients with atrial fibrillation. |
publishDate |
2013 |
dc.date.none.fl_str_mv |
2013-07-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/clinics/article/view/76930 10.1590/clin.v68i7.76930 |
url |
https://www.revistas.usp.br/clinics/article/view/76930 |
identifier_str_mv |
10.1590/clin.v68i7.76930 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/clinics/article/view/76930/80791 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo |
publisher.none.fl_str_mv |
Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo |
dc.source.none.fl_str_mv |
Clinics; Vol. 68 No. 7 (2013); 992-996 Clinics; v. 68 n. 7 (2013); 992-996 Clinics; Vol. 68 Núm. 7 (2013); 992-996 1980-5322 1807-5932 reponame:Clinics instname:Universidade de São Paulo (USP) instacron:USP |
instname_str |
Universidade de São Paulo (USP) |
instacron_str |
USP |
institution |
USP |
reponame_str |
Clinics |
collection |
Clinics |
repository.name.fl_str_mv |
Clinics - Universidade de São Paulo (USP) |
repository.mail.fl_str_mv |
||clinics@hc.fm.usp.br |
_version_ |
1800222760266366976 |