Comorbidities are frequent in patients with gastroesophageal reflux disease in a tertiary health care hospital

Detalhes bibliográficos
Autor(a) principal: Moraes-Filho, Joaquim Prado P
Data de Publicação: 2009
Outros Autores: Navarro-Rodriguez, Tomás, Eisig, Jaime N, Barbuti, Ricardo C, Chinzon, Decio, Quigley, Eamonn M M
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Clinics
Texto Completo: https://www.revistas.usp.br/clinics/article/view/17946
Resumo: INTRODUCTION: Several aspects of gastroesophageal reflux disease (GERD) have been studied, but the frequency of comorbidities is not yet fully understood. OBJECTIVES: To study the prevalence of GERD comorbidities in a tertiary care hospital. METHODS: We prospectively studied 670 consecutive adult patients from the outpatient department of our facility. A diagnosis was established using clinical, endoscopic and/or pHmetry-related findings. Each patient's medical file was reviewed with respect to the presence of other medical conditions and diagnoses. RESULTS: Of the 670 patients, 459 (68.6%) were female, and the mean age was 55.94 (17-80 years). We registered 316 patients (47.1%) with the erosive form of GERD and 354 patients (52.9%) with the non-erosive form. A total of 1,664 instances of comorbidities were recorded in 586 patients (87.5%), with the most common being arterial hypertension (21%), hypercholesterolemia (9%), obesity (9%), type II diabetes mellitus (5%) and depression (4%). Two or more comorbidities were present in 437 individuals (64.8%). The occurrence of comorbidities increased with age and was higher in patients with the non-erosive form of GERD. CONCLUSIONS: In a tertiary referral population, comorbidities were very common, and these may have worsened the already impaired health-related quality of life of these patients. Clinicians caring for GERD patients in this setting must be aware of the likelihood and nature of comorbid disorders and their impact on disease presentation and patient management.
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spelling Comorbidities are frequent in patients with gastroesophageal reflux disease in a tertiary health care hospital HeartburnRegurgitationGERD comorbiditiesEsophagitisEsophagus INTRODUCTION: Several aspects of gastroesophageal reflux disease (GERD) have been studied, but the frequency of comorbidities is not yet fully understood. OBJECTIVES: To study the prevalence of GERD comorbidities in a tertiary care hospital. METHODS: We prospectively studied 670 consecutive adult patients from the outpatient department of our facility. A diagnosis was established using clinical, endoscopic and/or pHmetry-related findings. Each patient's medical file was reviewed with respect to the presence of other medical conditions and diagnoses. RESULTS: Of the 670 patients, 459 (68.6%) were female, and the mean age was 55.94 (17-80 years). We registered 316 patients (47.1%) with the erosive form of GERD and 354 patients (52.9%) with the non-erosive form. A total of 1,664 instances of comorbidities were recorded in 586 patients (87.5%), with the most common being arterial hypertension (21%), hypercholesterolemia (9%), obesity (9%), type II diabetes mellitus (5%) and depression (4%). Two or more comorbidities were present in 437 individuals (64.8%). The occurrence of comorbidities increased with age and was higher in patients with the non-erosive form of GERD. CONCLUSIONS: In a tertiary referral population, comorbidities were very common, and these may have worsened the already impaired health-related quality of life of these patients. Clinicians caring for GERD patients in this setting must be aware of the likelihood and nature of comorbid disorders and their impact on disease presentation and patient management. Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo2009-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/clinics/article/view/1794610.1590/S1807-59322009000800013Clinics; Vol. 64 No. 8 (2009); 785-790 Clinics; v. 64 n. 8 (2009); 785-790 Clinics; Vol. 64 Núm. 8 (2009); 785-790 1980-53221807-5932reponame:Clinicsinstname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/clinics/article/view/17946/20011Moraes-Filho, Joaquim Prado PNavarro-Rodriguez, TomásEisig, Jaime NBarbuti, Ricardo CChinzon, DecioQuigley, Eamonn M Minfo:eu-repo/semantics/openAccess2012-05-22T18:47:23Zoai:revistas.usp.br:article/17946Revistahttps://www.revistas.usp.br/clinicsPUBhttps://www.revistas.usp.br/clinics/oai||clinics@hc.fm.usp.br1980-53221807-5932opendoar:2012-05-22T18:47:23Clinics - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv Comorbidities are frequent in patients with gastroesophageal reflux disease in a tertiary health care hospital
title Comorbidities are frequent in patients with gastroesophageal reflux disease in a tertiary health care hospital
spellingShingle Comorbidities are frequent in patients with gastroesophageal reflux disease in a tertiary health care hospital
Moraes-Filho, Joaquim Prado P
Heartburn
Regurgitation
GERD comorbidities
Esophagitis
Esophagus
title_short Comorbidities are frequent in patients with gastroesophageal reflux disease in a tertiary health care hospital
title_full Comorbidities are frequent in patients with gastroesophageal reflux disease in a tertiary health care hospital
title_fullStr Comorbidities are frequent in patients with gastroesophageal reflux disease in a tertiary health care hospital
title_full_unstemmed Comorbidities are frequent in patients with gastroesophageal reflux disease in a tertiary health care hospital
title_sort Comorbidities are frequent in patients with gastroesophageal reflux disease in a tertiary health care hospital
author Moraes-Filho, Joaquim Prado P
author_facet Moraes-Filho, Joaquim Prado P
Navarro-Rodriguez, Tomás
Eisig, Jaime N
Barbuti, Ricardo C
Chinzon, Decio
Quigley, Eamonn M M
author_role author
author2 Navarro-Rodriguez, Tomás
Eisig, Jaime N
Barbuti, Ricardo C
Chinzon, Decio
Quigley, Eamonn M M
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Moraes-Filho, Joaquim Prado P
Navarro-Rodriguez, Tomás
Eisig, Jaime N
Barbuti, Ricardo C
Chinzon, Decio
Quigley, Eamonn M M
dc.subject.por.fl_str_mv Heartburn
Regurgitation
GERD comorbidities
Esophagitis
Esophagus
topic Heartburn
Regurgitation
GERD comorbidities
Esophagitis
Esophagus
description INTRODUCTION: Several aspects of gastroesophageal reflux disease (GERD) have been studied, but the frequency of comorbidities is not yet fully understood. OBJECTIVES: To study the prevalence of GERD comorbidities in a tertiary care hospital. METHODS: We prospectively studied 670 consecutive adult patients from the outpatient department of our facility. A diagnosis was established using clinical, endoscopic and/or pHmetry-related findings. Each patient's medical file was reviewed with respect to the presence of other medical conditions and diagnoses. RESULTS: Of the 670 patients, 459 (68.6%) were female, and the mean age was 55.94 (17-80 years). We registered 316 patients (47.1%) with the erosive form of GERD and 354 patients (52.9%) with the non-erosive form. A total of 1,664 instances of comorbidities were recorded in 586 patients (87.5%), with the most common being arterial hypertension (21%), hypercholesterolemia (9%), obesity (9%), type II diabetes mellitus (5%) and depression (4%). Two or more comorbidities were present in 437 individuals (64.8%). The occurrence of comorbidities increased with age and was higher in patients with the non-erosive form of GERD. CONCLUSIONS: In a tertiary referral population, comorbidities were very common, and these may have worsened the already impaired health-related quality of life of these patients. Clinicians caring for GERD patients in this setting must be aware of the likelihood and nature of comorbid disorders and their impact on disease presentation and patient management.
publishDate 2009
dc.date.none.fl_str_mv 2009-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/clinics/article/view/17946
10.1590/S1807-59322009000800013
url https://www.revistas.usp.br/clinics/article/view/17946
identifier_str_mv 10.1590/S1807-59322009000800013
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.revistas.usp.br/clinics/article/view/17946/20011
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo
publisher.none.fl_str_mv Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo
dc.source.none.fl_str_mv Clinics; Vol. 64 No. 8 (2009); 785-790
Clinics; v. 64 n. 8 (2009); 785-790
Clinics; Vol. 64 Núm. 8 (2009); 785-790
1980-5322
1807-5932
reponame:Clinics
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Clinics
collection Clinics
repository.name.fl_str_mv Clinics - Universidade de São Paulo (USP)
repository.mail.fl_str_mv ||clinics@hc.fm.usp.br
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