Duas epidemias de tuberculose em crianças menores de três anos de idade, vacinadas com BCG oral, numa creche do município de São Paulo, Brasil

Detalhes bibliográficos
Autor(a) principal: Brólio, Roberto
Data de Publicação: 1974
Tipo de documento: Artigo
Idioma: por
Título da fonte: Revista de Saúde Pública
Texto Completo: https://www.revistas.usp.br/rsp/article/view/4747
Resumo: Two epidemics of tuberculosis in children under three years of age vaccinated with oral BCG, in the year of 1967 and 1969, in a day-nursery in S. Paulo borough, are here described. In 1967 there were 96 children in the place, at first non-reactors, to the standard tuberculine test (PPD, RT-23, 2UT). There were found 19 reactors, being 12 strong reactors (63,2%) and 7 weak reactors (36,8%), and in 15 children or 78,9% of the reactors, the chest X-Rays showed pulmonary abnormalitity. In 1969 there were 62 more children in the institution, initially non-reactors, who were followed-up separately in relation to the 1967 group, although they were in the same environment. There were found 36 reactors to tuberculine, being 29 strong reactors (80,5%) and 7 weak reactors (19,5%) and the chest X-Rays showed pulmonary abnormality in 11 children or 30,5% of the reactors. In that same year there was a tuberculine change in 7 more children, beloging to the non-reactor group of 1967, being 5 strong reactors and 2 weak ones. In both epidemics the tuberculinic changes and the alterations in the pulmonary X-Rays were manifested only in children under 3 years of age, the majority previously inoculated with 3 dosages of oral BCG, with one week interval between two dosages. The source of the infection was a workman who worked in the place among the children under 3 years of age, during approximately two months in 1967 and one month in 1969. The vaccine given by such a method seemed not to have influenced the tuberculine conversions and the development of the specific immunity.
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spelling Duas epidemias de tuberculose em crianças menores de três anos de idade, vacinadas com BCG oral, numa creche do município de São Paulo, Brasil Two epidemics of tuberculosis in children under three years of age vaccinated with oral BCG in a day-nursery in S. Paulo county, Brazil Infecção tuberculosaEpidemias^i1^sS. PauloBraCriançasVacinação BCGTuberculosis infectionEpidemics^i2^sS. Paulo (BrazBCG vaccination Two epidemics of tuberculosis in children under three years of age vaccinated with oral BCG, in the year of 1967 and 1969, in a day-nursery in S. Paulo borough, are here described. In 1967 there were 96 children in the place, at first non-reactors, to the standard tuberculine test (PPD, RT-23, 2UT). There were found 19 reactors, being 12 strong reactors (63,2%) and 7 weak reactors (36,8%), and in 15 children or 78,9% of the reactors, the chest X-Rays showed pulmonary abnormalitity. In 1969 there were 62 more children in the institution, initially non-reactors, who were followed-up separately in relation to the 1967 group, although they were in the same environment. There were found 36 reactors to tuberculine, being 29 strong reactors (80,5%) and 7 weak reactors (19,5%) and the chest X-Rays showed pulmonary abnormality in 11 children or 30,5% of the reactors. In that same year there was a tuberculine change in 7 more children, beloging to the non-reactor group of 1967, being 5 strong reactors and 2 weak ones. In both epidemics the tuberculinic changes and the alterations in the pulmonary X-Rays were manifested only in children under 3 years of age, the majority previously inoculated with 3 dosages of oral BCG, with one week interval between two dosages. The source of the infection was a workman who worked in the place among the children under 3 years of age, during approximately two months in 1967 and one month in 1969. The vaccine given by such a method seemed not to have influenced the tuberculine conversions and the development of the specific immunity. São descritas duas epidemias de tuberculose em crianças menores de 3 anos de idade vacinadas com BCG oral, ocorridas numa creche para crianças menores de 5 anos de idade, no município de São Paulo, nos anos de 1967 e 1969. Em 1967 havia no estabelecimento 96 crianças, inicialmente não reatoras ao teste tuberculínico padronizado (PPD, Rt-23, 2 UT). Foram encontrados 19 reatores, sendo 12 reatores fortes (63,2%) e 7 reatores fracos (36,8%) e imagens radiológicas indicativas de anormalidade pulmonar em 15 crianças ou 78,9% dos reatores. Em 1969 havia no estabelecimento mais 62 crianças não reatoras, que foram acompanhadas separadamente em relação ao grupo de 1967, embora convivessem no mesmo ambiente. Foram encontrados 36 reatores à tuberculina, sendo 29 reatores fortes (80,5%) e 7 reatores fracos (19,5%) e imagens radiológicas indicativas de anormalidade pulmonar em 11 crianças, ou 30,5% dos reatores. Nesse mesmo ano houve viragem tuberculínica em mais 7 crianças pertencentes ao grupo de não reatores de 1967, sendo 5 reatores fortes e 2 reatores fracos. Nas duas epidemias, as viragens tuberculínicas e as alterações radiológicas pulmonares foram constatadas apenas nas crianças menores de 3 anos de idade, em sua maioria vacinadas previamente com 3 doses de BCG oral, com intervalo de uma semana entre uma dose e outra. A fonte de infecção foi um operário que trabalhou no estabelecimento durante aproximadamente dois meses em 1967 e um mês em 1969, nos locais onde eram mantidas as crianças menores de 3 anos de idade. A vacina administrada por esse método não parece ter influenciado nas conversões tuberculínicas e no desenvolvimento de imunidade específica. Universidade de São Paulo. Faculdade de Saúde Pública1974-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/rsp/article/view/474710.1590/S0034-89101974000300004Revista de Saúde Pública; Vol. 8 No. 3 (1974); 283-296 Revista de Saúde Pública; Vol. 8 Núm. 3 (1974); 283-296 Revista de Saúde Pública; v. 8 n. 3 (1974); 283-296 1518-87870034-8910reponame:Revista de Saúde Públicainstname:Universidade de São Paulo (USP)instacron:USPporhttps://www.revistas.usp.br/rsp/article/view/4747/6277Copyright (c) 2017 Revista de Saúde Públicainfo:eu-repo/semantics/openAccessBrólio, Roberto2012-04-27T19:09:57Zoai:revistas.usp.br:article/4747Revistahttps://www.revistas.usp.br/rsp/indexONGhttps://www.revistas.usp.br/rsp/oairevsp@org.usp.br||revsp1@usp.br1518-87870034-8910opendoar:2012-04-27T19:09:57Revista de Saúde Pública - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv Duas epidemias de tuberculose em crianças menores de três anos de idade, vacinadas com BCG oral, numa creche do município de São Paulo, Brasil
Two epidemics of tuberculosis in children under three years of age vaccinated with oral BCG in a day-nursery in S. Paulo county, Brazil
title Duas epidemias de tuberculose em crianças menores de três anos de idade, vacinadas com BCG oral, numa creche do município de São Paulo, Brasil
spellingShingle Duas epidemias de tuberculose em crianças menores de três anos de idade, vacinadas com BCG oral, numa creche do município de São Paulo, Brasil
Brólio, Roberto
Infecção tuberculosa
Epidemias^i1^sS. Paulo
Bra
Crianças
Vacinação BCG
Tuberculosis infection
Epidemics^i2^sS. Paulo (Braz
BCG vaccination
title_short Duas epidemias de tuberculose em crianças menores de três anos de idade, vacinadas com BCG oral, numa creche do município de São Paulo, Brasil
title_full Duas epidemias de tuberculose em crianças menores de três anos de idade, vacinadas com BCG oral, numa creche do município de São Paulo, Brasil
title_fullStr Duas epidemias de tuberculose em crianças menores de três anos de idade, vacinadas com BCG oral, numa creche do município de São Paulo, Brasil
title_full_unstemmed Duas epidemias de tuberculose em crianças menores de três anos de idade, vacinadas com BCG oral, numa creche do município de São Paulo, Brasil
title_sort Duas epidemias de tuberculose em crianças menores de três anos de idade, vacinadas com BCG oral, numa creche do município de São Paulo, Brasil
author Brólio, Roberto
author_facet Brólio, Roberto
author_role author
dc.contributor.author.fl_str_mv Brólio, Roberto
dc.subject.por.fl_str_mv Infecção tuberculosa
Epidemias^i1^sS. Paulo
Bra
Crianças
Vacinação BCG
Tuberculosis infection
Epidemics^i2^sS. Paulo (Braz
BCG vaccination
topic Infecção tuberculosa
Epidemias^i1^sS. Paulo
Bra
Crianças
Vacinação BCG
Tuberculosis infection
Epidemics^i2^sS. Paulo (Braz
BCG vaccination
description Two epidemics of tuberculosis in children under three years of age vaccinated with oral BCG, in the year of 1967 and 1969, in a day-nursery in S. Paulo borough, are here described. In 1967 there were 96 children in the place, at first non-reactors, to the standard tuberculine test (PPD, RT-23, 2UT). There were found 19 reactors, being 12 strong reactors (63,2%) and 7 weak reactors (36,8%), and in 15 children or 78,9% of the reactors, the chest X-Rays showed pulmonary abnormalitity. In 1969 there were 62 more children in the institution, initially non-reactors, who were followed-up separately in relation to the 1967 group, although they were in the same environment. There were found 36 reactors to tuberculine, being 29 strong reactors (80,5%) and 7 weak reactors (19,5%) and the chest X-Rays showed pulmonary abnormality in 11 children or 30,5% of the reactors. In that same year there was a tuberculine change in 7 more children, beloging to the non-reactor group of 1967, being 5 strong reactors and 2 weak ones. In both epidemics the tuberculinic changes and the alterations in the pulmonary X-Rays were manifested only in children under 3 years of age, the majority previously inoculated with 3 dosages of oral BCG, with one week interval between two dosages. The source of the infection was a workman who worked in the place among the children under 3 years of age, during approximately two months in 1967 and one month in 1969. The vaccine given by such a method seemed not to have influenced the tuberculine conversions and the development of the specific immunity.
publishDate 1974
dc.date.none.fl_str_mv 1974-09-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/rsp/article/view/4747
10.1590/S0034-89101974000300004
url https://www.revistas.usp.br/rsp/article/view/4747
identifier_str_mv 10.1590/S0034-89101974000300004
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://www.revistas.usp.br/rsp/article/view/4747/6277
dc.rights.driver.fl_str_mv Copyright (c) 2017 Revista de Saúde Pública
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2017 Revista de Saúde Pública
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Saúde Pública
publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Saúde Pública
dc.source.none.fl_str_mv Revista de Saúde Pública; Vol. 8 No. 3 (1974); 283-296
Revista de Saúde Pública; Vol. 8 Núm. 3 (1974); 283-296
Revista de Saúde Pública; v. 8 n. 3 (1974); 283-296
1518-8787
0034-8910
reponame:Revista de Saúde Pública
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Revista de Saúde Pública
collection Revista de Saúde Pública
repository.name.fl_str_mv Revista de Saúde Pública - Universidade de São Paulo (USP)
repository.mail.fl_str_mv revsp@org.usp.br||revsp1@usp.br
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