Dengue epidemic in a Northeastern Brazil: random epidemiological serum survey
Autor(a) principal: | |
---|---|
Data de Publicação: | 1998 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Revista de Saúde Pública |
Texto Completo: | https://www.revistas.usp.br/rsp/article/view/24402 |
Resumo: | OBJECTIVE: A seroepidemiological random survey was carried out in Fortaleza city, State of Ceará, Brazil, following an epidemic of dengue virus type 2 (DEN 2), with the purpose of evaluating the frequency of clinical manifestations (signs and symptoms) and the prevalence of dengue infection. METHOD: A questionnaire calling for information on address, sex, age, clinical, epidemiological and economic status was applied to the population, followed by venupuncture collection of 5-10 ml of blood for testing by hemagglutination-inhibition (HI). The sample was calculated to obtain a prevalence of 20% with relative risk of 10% and confidence interval of 95%. All information obtained was analyzed by computer using Epi Info 5.0®, Lotus 123®, Excel 5.0®, and Stata® software. RESULTS AND CONCLUSIONS: A total of 1,341 serum samples were obtained from nine Health Districts (SD) and tested by hemagglutination inhibition. Of these, 589 (44%) were positive and 752 (56%) negative. Of the positive results, 93 primary responses (PR) (7%) to DEN-2 and 496 secondary responses (SR) (37%) were observed. The global prevalence in the SD ranged from 21% to 71%. There were 41% (243/589) asymptomatic infections and 59% (346/589) symptomatic infections. Data analysis showed no difference in frequency by sex, age, on schooling, although a highly statistically significant difference was found as between the different social classes, the infection most commonly observed being among people of better social status.The stratification of positive cases showed greater prevalence of AI (p |
id |
USP-23_9bd73948bedade436270a01999200b58 |
---|---|
oai_identifier_str |
oai:revistas.usp.br:article/24402 |
network_acronym_str |
USP-23 |
network_name_str |
Revista de Saúde Pública |
repository_id_str |
|
spelling |
Dengue epidemic in a Northeastern Brazil: random epidemiological serum survey Epidemia de dengue em Fortaleza, Ceará: inquérito soro-epidemiológico aleatório Dengue^i1^sepidemioloMétodos soroepidemiológicosPrevalênciaDengue^i2^sepidemiolSeroepidemiologic methodsPrevalence OBJECTIVE: A seroepidemiological random survey was carried out in Fortaleza city, State of Ceará, Brazil, following an epidemic of dengue virus type 2 (DEN 2), with the purpose of evaluating the frequency of clinical manifestations (signs and symptoms) and the prevalence of dengue infection. METHOD: A questionnaire calling for information on address, sex, age, clinical, epidemiological and economic status was applied to the population, followed by venupuncture collection of 5-10 ml of blood for testing by hemagglutination-inhibition (HI). The sample was calculated to obtain a prevalence of 20% with relative risk of 10% and confidence interval of 95%. All information obtained was analyzed by computer using Epi Info 5.0®, Lotus 123®, Excel 5.0®, and Stata® software. RESULTS AND CONCLUSIONS: A total of 1,341 serum samples were obtained from nine Health Districts (SD) and tested by hemagglutination inhibition. Of these, 589 (44%) were positive and 752 (56%) negative. Of the positive results, 93 primary responses (PR) (7%) to DEN-2 and 496 secondary responses (SR) (37%) were observed. The global prevalence in the SD ranged from 21% to 71%. There were 41% (243/589) asymptomatic infections and 59% (346/589) symptomatic infections. Data analysis showed no difference in frequency by sex, age, on schooling, although a highly statistically significant difference was found as between the different social classes, the infection most commonly observed being among people of better social status.The stratification of positive cases showed greater prevalence of AI (p OBJETIVO: Seguindo-se à epidemia de dengue (DEN), em 1994, em Fortaleza, Ceará, causada pelo sorotipo 2 (DEN-2), realizou-se inquérito soro-epidemiológico aleatório para avaliar e dimensionar o impacto da mesma e a prevalência do dengue por distrito sanitário. MÉTODO: Foi aplicado questionário contendo informações gerais, condições socio-econômicas, informações sobre o quadro clínico e tempo de doença. A amostra foi calculada para estimar uma prevalência de 20%, com erro relativo de 10%, e intervalo de confiança de 95% (erro a de 5%). O sorteio e as análises foram realizadas por meio de computador usando programas apropriados. RESULTADOS E CONCLUSÕES: Foram colhidas 1.341 amostras de soro de 9 distritos sanitários, testadas por inibição da hemaglutinação, sendo classificadas como negativas e positivas (respostas primária - RP e secundária - RS). Foram reativas 588 (44%) amostras, sendo 93 (7%) RP e 495 (37%) RS. A prevalência global em Fortaleza variou de 21% a 71%. Houve 41% (243/588) de infecções assintomáticas (IA) e 59% (346/588) sintomáticas (IS). Não houve diferença da prevalência quanto ao sexo, faixa etária e escolaridade, ao contrário da condição socioeconômica que apresentou diferenças estatisticamente significantes (p < 0,001). Ocorreram mais IA (pUniversidade de São Paulo. Faculdade de Saúde Pública1998-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/rsp/article/view/2440210.1590/S0034-89101998000500007Revista de Saúde Pública; Vol. 32 No. 5 (1998); 447-454 Revista de Saúde Pública; Vol. 32 Núm. 5 (1998); 447-454 Revista de Saúde Pública; v. 32 n. 5 (1998); 447-454 1518-87870034-8910reponame:Revista de Saúde Públicainstname:Universidade de São Paulo (USP)instacron:USPporhttps://www.revistas.usp.br/rsp/article/view/24402/26326Copyright (c) 2017 Revista de Saúde Públicainfo:eu-repo/semantics/openAccessVasconcelos, Pedro F. C.Lima, José Wellington O.Rosa, Amélia P. A. Travassos daTimbó, Maria J.Rosa, Elizabeth S. Travassos daLima, Hascalon R.Rodrigues, Sueli G.Rosa, Jorge F. S. Travassos da2012-05-29T17:00:03Zoai:revistas.usp.br:article/24402Revistahttps://www.revistas.usp.br/rsp/indexONGhttps://www.revistas.usp.br/rsp/oairevsp@org.usp.br||revsp1@usp.br1518-87870034-8910opendoar:2012-05-29T17:00:03Revista de Saúde Pública - Universidade de São Paulo (USP)false |
dc.title.none.fl_str_mv |
Dengue epidemic in a Northeastern Brazil: random epidemiological serum survey Epidemia de dengue em Fortaleza, Ceará: inquérito soro-epidemiológico aleatório |
title |
Dengue epidemic in a Northeastern Brazil: random epidemiological serum survey |
spellingShingle |
Dengue epidemic in a Northeastern Brazil: random epidemiological serum survey Vasconcelos, Pedro F. C. Dengue^i1^sepidemiolo Métodos soroepidemiológicos Prevalência Dengue^i2^sepidemiol Seroepidemiologic methods Prevalence |
title_short |
Dengue epidemic in a Northeastern Brazil: random epidemiological serum survey |
title_full |
Dengue epidemic in a Northeastern Brazil: random epidemiological serum survey |
title_fullStr |
Dengue epidemic in a Northeastern Brazil: random epidemiological serum survey |
title_full_unstemmed |
Dengue epidemic in a Northeastern Brazil: random epidemiological serum survey |
title_sort |
Dengue epidemic in a Northeastern Brazil: random epidemiological serum survey |
author |
Vasconcelos, Pedro F. C. |
author_facet |
Vasconcelos, Pedro F. C. Lima, José Wellington O. Rosa, Amélia P. A. Travassos da Timbó, Maria J. Rosa, Elizabeth S. Travassos da Lima, Hascalon R. Rodrigues, Sueli G. Rosa, Jorge F. S. Travassos da |
author_role |
author |
author2 |
Lima, José Wellington O. Rosa, Amélia P. A. Travassos da Timbó, Maria J. Rosa, Elizabeth S. Travassos da Lima, Hascalon R. Rodrigues, Sueli G. Rosa, Jorge F. S. Travassos da |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Vasconcelos, Pedro F. C. Lima, José Wellington O. Rosa, Amélia P. A. Travassos da Timbó, Maria J. Rosa, Elizabeth S. Travassos da Lima, Hascalon R. Rodrigues, Sueli G. Rosa, Jorge F. S. Travassos da |
dc.subject.por.fl_str_mv |
Dengue^i1^sepidemiolo Métodos soroepidemiológicos Prevalência Dengue^i2^sepidemiol Seroepidemiologic methods Prevalence |
topic |
Dengue^i1^sepidemiolo Métodos soroepidemiológicos Prevalência Dengue^i2^sepidemiol Seroepidemiologic methods Prevalence |
description |
OBJECTIVE: A seroepidemiological random survey was carried out in Fortaleza city, State of Ceará, Brazil, following an epidemic of dengue virus type 2 (DEN 2), with the purpose of evaluating the frequency of clinical manifestations (signs and symptoms) and the prevalence of dengue infection. METHOD: A questionnaire calling for information on address, sex, age, clinical, epidemiological and economic status was applied to the population, followed by venupuncture collection of 5-10 ml of blood for testing by hemagglutination-inhibition (HI). The sample was calculated to obtain a prevalence of 20% with relative risk of 10% and confidence interval of 95%. All information obtained was analyzed by computer using Epi Info 5.0®, Lotus 123®, Excel 5.0®, and Stata® software. RESULTS AND CONCLUSIONS: A total of 1,341 serum samples were obtained from nine Health Districts (SD) and tested by hemagglutination inhibition. Of these, 589 (44%) were positive and 752 (56%) negative. Of the positive results, 93 primary responses (PR) (7%) to DEN-2 and 496 secondary responses (SR) (37%) were observed. The global prevalence in the SD ranged from 21% to 71%. There were 41% (243/589) asymptomatic infections and 59% (346/589) symptomatic infections. Data analysis showed no difference in frequency by sex, age, on schooling, although a highly statistically significant difference was found as between the different social classes, the infection most commonly observed being among people of better social status.The stratification of positive cases showed greater prevalence of AI (p |
publishDate |
1998 |
dc.date.none.fl_str_mv |
1998-10-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/rsp/article/view/24402 10.1590/S0034-89101998000500007 |
url |
https://www.revistas.usp.br/rsp/article/view/24402 |
identifier_str_mv |
10.1590/S0034-89101998000500007 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/rsp/article/view/24402/26326 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2017 Revista de Saúde Pública info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2017 Revista de Saúde Pública |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade de São Paulo. Faculdade de Saúde Pública |
publisher.none.fl_str_mv |
Universidade de São Paulo. Faculdade de Saúde Pública |
dc.source.none.fl_str_mv |
Revista de Saúde Pública; Vol. 32 No. 5 (1998); 447-454 Revista de Saúde Pública; Vol. 32 Núm. 5 (1998); 447-454 Revista de Saúde Pública; v. 32 n. 5 (1998); 447-454 1518-8787 0034-8910 reponame:Revista de Saúde Pública instname:Universidade de São Paulo (USP) instacron:USP |
instname_str |
Universidade de São Paulo (USP) |
instacron_str |
USP |
institution |
USP |
reponame_str |
Revista de Saúde Pública |
collection |
Revista de Saúde Pública |
repository.name.fl_str_mv |
Revista de Saúde Pública - Universidade de São Paulo (USP) |
repository.mail.fl_str_mv |
revsp@org.usp.br||revsp1@usp.br |
_version_ |
1800221778539184128 |