Dengue epidemic in a Northeastern Brazil: random epidemiological serum survey

Detalhes bibliográficos
Autor(a) principal: Vasconcelos, Pedro F. C.
Data de Publicação: 1998
Outros Autores: Lima, José Wellington O., Rosa, Amélia P. A. Travassos da, Timbó, Maria J., Rosa, Elizabeth S. Travassos da, Lima, Hascalon R., Rodrigues, Sueli G., Rosa, Jorge F. S. Travassos da
Tipo de documento: Artigo
Idioma: por
Título da fonte: Revista de Saúde Pública
Texto Completo: https://www.revistas.usp.br/rsp/article/view/24402
Resumo: OBJECTIVE: A seroepidemiological random survey was carried out in Fortaleza city, State of Ceará, Brazil, following an epidemic of dengue virus type 2 (DEN 2), with the purpose of evaluating the frequency of clinical manifestations (signs and symptoms) and the prevalence of dengue infection. METHOD: A questionnaire calling for information on address, sex, age, clinical, epidemiological and economic status was applied to the population, followed by venupuncture collection of 5-10 ml of blood for testing by hemagglutination-inhibition (HI). The sample was calculated to obtain a prevalence of 20% with relative risk of 10% and confidence interval of 95%. All information obtained was analyzed by computer using Epi Info 5.0®, Lotus 123®, Excel 5.0®, and Stata® software. RESULTS AND CONCLUSIONS: A total of 1,341 serum samples were obtained from nine Health Districts (SD) and tested by hemagglutination inhibition. Of these, 589 (44%) were positive and 752 (56%) negative. Of the positive results, 93 primary responses (PR) (7%) to DEN-2 and 496 secondary responses (SR) (37%) were observed. The global prevalence in the SD ranged from 21% to 71%. There were 41% (243/589) asymptomatic infections and 59% (346/589) symptomatic infections. Data analysis showed no difference in frequency by sex, age, on schooling, although a highly statistically significant difference was found as between the different social classes, the infection most commonly observed being among people of better social status.The stratification of positive cases showed greater prevalence of AI (p
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spelling Dengue epidemic in a Northeastern Brazil: random epidemiological serum survey Epidemia de dengue em Fortaleza, Ceará: inquérito soro-epidemiológico aleatório Dengue^i1^sepidemioloMétodos soroepidemiológicosPrevalênciaDengue^i2^sepidemiolSeroepidemiologic methodsPrevalence OBJECTIVE: A seroepidemiological random survey was carried out in Fortaleza city, State of Ceará, Brazil, following an epidemic of dengue virus type 2 (DEN 2), with the purpose of evaluating the frequency of clinical manifestations (signs and symptoms) and the prevalence of dengue infection. METHOD: A questionnaire calling for information on address, sex, age, clinical, epidemiological and economic status was applied to the population, followed by venupuncture collection of 5-10 ml of blood for testing by hemagglutination-inhibition (HI). The sample was calculated to obtain a prevalence of 20% with relative risk of 10% and confidence interval of 95%. All information obtained was analyzed by computer using Epi Info 5.0®, Lotus 123®, Excel 5.0®, and Stata® software. RESULTS AND CONCLUSIONS: A total of 1,341 serum samples were obtained from nine Health Districts (SD) and tested by hemagglutination inhibition. Of these, 589 (44%) were positive and 752 (56%) negative. Of the positive results, 93 primary responses (PR) (7%) to DEN-2 and 496 secondary responses (SR) (37%) were observed. The global prevalence in the SD ranged from 21% to 71%. There were 41% (243/589) asymptomatic infections and 59% (346/589) symptomatic infections. Data analysis showed no difference in frequency by sex, age, on schooling, although a highly statistically significant difference was found as between the different social classes, the infection most commonly observed being among people of better social status.The stratification of positive cases showed greater prevalence of AI (p OBJETIVO: Seguindo-se à epidemia de dengue (DEN), em 1994, em Fortaleza, Ceará, causada pelo sorotipo 2 (DEN-2), realizou-se inquérito soro-epidemiológico aleatório para avaliar e dimensionar o impacto da mesma e a prevalência do dengue por distrito sanitário. MÉTODO: Foi aplicado questionário contendo informações gerais, condições socio-econômicas, informações sobre o quadro clínico e tempo de doença. A amostra foi calculada para estimar uma prevalência de 20%, com erro relativo de 10%, e intervalo de confiança de 95% (erro a de 5%). O sorteio e as análises foram realizadas por meio de computador usando programas apropriados. RESULTADOS E CONCLUSÕES: Foram colhidas 1.341 amostras de soro de 9 distritos sanitários, testadas por inibição da hemaglutinação, sendo classificadas como negativas e positivas (respostas primária - RP e secundária - RS). Foram reativas 588 (44%) amostras, sendo 93 (7%) RP e 495 (37%) RS. A prevalência global em Fortaleza variou de 21% a 71%. Houve 41% (243/588) de infecções assintomáticas (IA) e 59% (346/588) sintomáticas (IS). Não houve diferença da prevalência quanto ao sexo, faixa etária e escolaridade, ao contrário da condição socioeconômica que apresentou diferenças estatisticamente significantes (p < 0,001). Ocorreram mais IA (pUniversidade de São Paulo. Faculdade de Saúde Pública1998-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/rsp/article/view/2440210.1590/S0034-89101998000500007Revista de Saúde Pública; Vol. 32 No. 5 (1998); 447-454 Revista de Saúde Pública; Vol. 32 Núm. 5 (1998); 447-454 Revista de Saúde Pública; v. 32 n. 5 (1998); 447-454 1518-87870034-8910reponame:Revista de Saúde Públicainstname:Universidade de São Paulo (USP)instacron:USPporhttps://www.revistas.usp.br/rsp/article/view/24402/26326Copyright (c) 2017 Revista de Saúde Públicainfo:eu-repo/semantics/openAccessVasconcelos, Pedro F. C.Lima, José Wellington O.Rosa, Amélia P. A. Travassos daTimbó, Maria J.Rosa, Elizabeth S. Travassos daLima, Hascalon R.Rodrigues, Sueli G.Rosa, Jorge F. S. Travassos da2012-05-29T17:00:03Zoai:revistas.usp.br:article/24402Revistahttps://www.revistas.usp.br/rsp/indexONGhttps://www.revistas.usp.br/rsp/oairevsp@org.usp.br||revsp1@usp.br1518-87870034-8910opendoar:2012-05-29T17:00:03Revista de Saúde Pública - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv Dengue epidemic in a Northeastern Brazil: random epidemiological serum survey
Epidemia de dengue em Fortaleza, Ceará: inquérito soro-epidemiológico aleatório
title Dengue epidemic in a Northeastern Brazil: random epidemiological serum survey
spellingShingle Dengue epidemic in a Northeastern Brazil: random epidemiological serum survey
Vasconcelos, Pedro F. C.
Dengue^i1^sepidemiolo
Métodos soroepidemiológicos
Prevalência
Dengue^i2^sepidemiol
Seroepidemiologic methods
Prevalence
title_short Dengue epidemic in a Northeastern Brazil: random epidemiological serum survey
title_full Dengue epidemic in a Northeastern Brazil: random epidemiological serum survey
title_fullStr Dengue epidemic in a Northeastern Brazil: random epidemiological serum survey
title_full_unstemmed Dengue epidemic in a Northeastern Brazil: random epidemiological serum survey
title_sort Dengue epidemic in a Northeastern Brazil: random epidemiological serum survey
author Vasconcelos, Pedro F. C.
author_facet Vasconcelos, Pedro F. C.
Lima, José Wellington O.
Rosa, Amélia P. A. Travassos da
Timbó, Maria J.
Rosa, Elizabeth S. Travassos da
Lima, Hascalon R.
Rodrigues, Sueli G.
Rosa, Jorge F. S. Travassos da
author_role author
author2 Lima, José Wellington O.
Rosa, Amélia P. A. Travassos da
Timbó, Maria J.
Rosa, Elizabeth S. Travassos da
Lima, Hascalon R.
Rodrigues, Sueli G.
Rosa, Jorge F. S. Travassos da
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Vasconcelos, Pedro F. C.
Lima, José Wellington O.
Rosa, Amélia P. A. Travassos da
Timbó, Maria J.
Rosa, Elizabeth S. Travassos da
Lima, Hascalon R.
Rodrigues, Sueli G.
Rosa, Jorge F. S. Travassos da
dc.subject.por.fl_str_mv Dengue^i1^sepidemiolo
Métodos soroepidemiológicos
Prevalência
Dengue^i2^sepidemiol
Seroepidemiologic methods
Prevalence
topic Dengue^i1^sepidemiolo
Métodos soroepidemiológicos
Prevalência
Dengue^i2^sepidemiol
Seroepidemiologic methods
Prevalence
description OBJECTIVE: A seroepidemiological random survey was carried out in Fortaleza city, State of Ceará, Brazil, following an epidemic of dengue virus type 2 (DEN 2), with the purpose of evaluating the frequency of clinical manifestations (signs and symptoms) and the prevalence of dengue infection. METHOD: A questionnaire calling for information on address, sex, age, clinical, epidemiological and economic status was applied to the population, followed by venupuncture collection of 5-10 ml of blood for testing by hemagglutination-inhibition (HI). The sample was calculated to obtain a prevalence of 20% with relative risk of 10% and confidence interval of 95%. All information obtained was analyzed by computer using Epi Info 5.0®, Lotus 123®, Excel 5.0®, and Stata® software. RESULTS AND CONCLUSIONS: A total of 1,341 serum samples were obtained from nine Health Districts (SD) and tested by hemagglutination inhibition. Of these, 589 (44%) were positive and 752 (56%) negative. Of the positive results, 93 primary responses (PR) (7%) to DEN-2 and 496 secondary responses (SR) (37%) were observed. The global prevalence in the SD ranged from 21% to 71%. There were 41% (243/589) asymptomatic infections and 59% (346/589) symptomatic infections. Data analysis showed no difference in frequency by sex, age, on schooling, although a highly statistically significant difference was found as between the different social classes, the infection most commonly observed being among people of better social status.The stratification of positive cases showed greater prevalence of AI (p
publishDate 1998
dc.date.none.fl_str_mv 1998-10-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/rsp/article/view/24402
10.1590/S0034-89101998000500007
url https://www.revistas.usp.br/rsp/article/view/24402
identifier_str_mv 10.1590/S0034-89101998000500007
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dc.relation.none.fl_str_mv https://www.revistas.usp.br/rsp/article/view/24402/26326
dc.rights.driver.fl_str_mv Copyright (c) 2017 Revista de Saúde Pública
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2017 Revista de Saúde Pública
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Saúde Pública
publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Saúde Pública
dc.source.none.fl_str_mv Revista de Saúde Pública; Vol. 32 No. 5 (1998); 447-454
Revista de Saúde Pública; Vol. 32 Núm. 5 (1998); 447-454
Revista de Saúde Pública; v. 32 n. 5 (1998); 447-454
1518-8787
0034-8910
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instname_str Universidade de São Paulo (USP)
instacron_str USP
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reponame_str Revista de Saúde Pública
collection Revista de Saúde Pública
repository.name.fl_str_mv Revista de Saúde Pública - Universidade de São Paulo (USP)
repository.mail.fl_str_mv revsp@org.usp.br||revsp1@usp.br
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