Infectious events in kidney transplant recipients from deceased expanded criteria donors: a prospective cohort

• Autor(a) principal: Sousa,Sirlei Regina de
• Data de Publicação: 2021
• Outros Autores: Fonseca,Cassiane Dezoti da, Taminato,Monica, Vattimo,Maria de Fatima Fernandes, Belasco,Angélica Gonçalves Silva, Sousa,Álvaro Francisco Lopes de, Fronteira,Inês, Barbosa,Dulce Aparecida
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Revista da Escola de Enfermagem da USP (Online)
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0080-62342021000100553
• topic: Infections; Kidney Transplantation; Transplants; Mortality; Survival rate

ABSTRACT Objective: Analyze risk factors for infection in kidney transplant recipients from deceased expanded criteria donors (DECD) in the first two years of follow-up. Method: This is a prospective cohort study with 466 patients from DECD who underwent kidney transplantation in 2015 and 2016 in Brazil. A total of 551 events were recorded. The largest incidence of infectious events occurred in the first month after kidney transplantation. Cytomegalovirus infection was the most common infectious episode. Results: The incidence rate of infections was 57.1%. Among bacterial infections, only 4% were due to multidrug-resistant microorganisms. The death rate was 3.3% (15) patients. The main cause of death was infectious (73.3%). Hospitalization until the first infection (aOR:1.61), Number of infections in 1 year (aOR:40.16), and Cytomegalovirus infection (aOR:13.84) was risk factors for infection by multidrug resistant microorganisms (MDR). Conclusion: Infection incidence with MDR bacteria was high among kidney transplant recipients from DECD, and the main cause of death was infection. Survival was high among patients with infection.