Halloysite nanotubes-polymeric nanocomposites: characteristics, modifications and controlled drug delivery approaches
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Cerâmica (São Paulo. Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0366-69132017000400423 |
Resumo: | Abstract Halloysite nanotubes (HNTs) are aluminosilicate nanoclay mineral which have a hollow tubular structure and occurs naturally. They are biocompatible and viable carrier for inclusion of biologically active molecules due to the empty space inside the tubular structure. In this article, the HNTs main characteristics, and the HNTs-polymeric nanocomposite formation and their potential application as improvement of the mechanical performance of polymers and entrapment of hydrophilic and lipophilic substances are summarized. Recent works covering the increment of HNTs-polymeric nanocomposites and presenting promising employment of these systems as nanosized carrier, being suitable for pharmaceutical and biomedical applications, based on earlier evidence in literature of its nature to sustain the release of loaded drugs, presenting low cytotoxicity, and providing evidence for controlled drug delivery are reviewed. |
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Cerâmica (São Paulo. Online) |
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Halloysite nanotubes-polymeric nanocomposites: characteristics, modifications and controlled drug delivery approachesnanoclaybio-nanocompositesfunctionalizationsustained drug releasenanotechnologyAbstract Halloysite nanotubes (HNTs) are aluminosilicate nanoclay mineral which have a hollow tubular structure and occurs naturally. They are biocompatible and viable carrier for inclusion of biologically active molecules due to the empty space inside the tubular structure. In this article, the HNTs main characteristics, and the HNTs-polymeric nanocomposite formation and their potential application as improvement of the mechanical performance of polymers and entrapment of hydrophilic and lipophilic substances are summarized. Recent works covering the increment of HNTs-polymeric nanocomposites and presenting promising employment of these systems as nanosized carrier, being suitable for pharmaceutical and biomedical applications, based on earlier evidence in literature of its nature to sustain the release of loaded drugs, presenting low cytotoxicity, and providing evidence for controlled drug delivery are reviewed.Associação Brasileira de Cerâmica2017-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0366-69132017000400423Cerâmica v.63 n.368 2017reponame:Cerâmica (São Paulo. Online)instname:Universidade de São Paulo (USP)instacron:USP10.1590/0366-69132017633682167info:eu-repo/semantics/openAccessFerrari,P. C.Araujo,F. F.Pianaro,S. A.eng2017-11-30T00:00:00Zoai:scielo:S0366-69132017000400423Revistahttps://www.scielo.br/j/ce/PUBhttps://old.scielo.br/oai/scielo-oai.phpceram.abc@gmail.com||ceram.abc@gmail.com1678-45530366-6913opendoar:2017-11-30T00:00Cerâmica (São Paulo. Online) - Universidade de São Paulo (USP)false |
dc.title.none.fl_str_mv |
Halloysite nanotubes-polymeric nanocomposites: characteristics, modifications and controlled drug delivery approaches |
title |
Halloysite nanotubes-polymeric nanocomposites: characteristics, modifications and controlled drug delivery approaches |
spellingShingle |
Halloysite nanotubes-polymeric nanocomposites: characteristics, modifications and controlled drug delivery approaches Ferrari,P. C. nanoclay bio-nanocomposites functionalization sustained drug release nanotechnology |
title_short |
Halloysite nanotubes-polymeric nanocomposites: characteristics, modifications and controlled drug delivery approaches |
title_full |
Halloysite nanotubes-polymeric nanocomposites: characteristics, modifications and controlled drug delivery approaches |
title_fullStr |
Halloysite nanotubes-polymeric nanocomposites: characteristics, modifications and controlled drug delivery approaches |
title_full_unstemmed |
Halloysite nanotubes-polymeric nanocomposites: characteristics, modifications and controlled drug delivery approaches |
title_sort |
Halloysite nanotubes-polymeric nanocomposites: characteristics, modifications and controlled drug delivery approaches |
author |
Ferrari,P. C. |
author_facet |
Ferrari,P. C. Araujo,F. F. Pianaro,S. A. |
author_role |
author |
author2 |
Araujo,F. F. Pianaro,S. A. |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Ferrari,P. C. Araujo,F. F. Pianaro,S. A. |
dc.subject.por.fl_str_mv |
nanoclay bio-nanocomposites functionalization sustained drug release nanotechnology |
topic |
nanoclay bio-nanocomposites functionalization sustained drug release nanotechnology |
description |
Abstract Halloysite nanotubes (HNTs) are aluminosilicate nanoclay mineral which have a hollow tubular structure and occurs naturally. They are biocompatible and viable carrier for inclusion of biologically active molecules due to the empty space inside the tubular structure. In this article, the HNTs main characteristics, and the HNTs-polymeric nanocomposite formation and their potential application as improvement of the mechanical performance of polymers and entrapment of hydrophilic and lipophilic substances are summarized. Recent works covering the increment of HNTs-polymeric nanocomposites and presenting promising employment of these systems as nanosized carrier, being suitable for pharmaceutical and biomedical applications, based on earlier evidence in literature of its nature to sustain the release of loaded drugs, presenting low cytotoxicity, and providing evidence for controlled drug delivery are reviewed. |
publishDate |
2017 |
dc.date.none.fl_str_mv |
2017-12-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0366-69132017000400423 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0366-69132017000400423 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/0366-69132017633682167 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Associação Brasileira de Cerâmica |
publisher.none.fl_str_mv |
Associação Brasileira de Cerâmica |
dc.source.none.fl_str_mv |
Cerâmica v.63 n.368 2017 reponame:Cerâmica (São Paulo. Online) instname:Universidade de São Paulo (USP) instacron:USP |
instname_str |
Universidade de São Paulo (USP) |
instacron_str |
USP |
institution |
USP |
reponame_str |
Cerâmica (São Paulo. Online) |
collection |
Cerâmica (São Paulo. Online) |
repository.name.fl_str_mv |
Cerâmica (São Paulo. Online) - Universidade de São Paulo (USP) |
repository.mail.fl_str_mv |
ceram.abc@gmail.com||ceram.abc@gmail.com |
_version_ |
1748936783840673792 |