Antihypoxic activities of Crataegus pentaegyn and Crataegus microphylla fruits-an in vivo assay

Detalhes bibliográficos
Autor(a) principal: Ebrahimzadeh, Mohammad Ali
Data de Publicação: 2018
Outros Autores: Khalili, Masoumeh, Jafari, Negar, Zareh, Giti, Farzin, Davood, Amin, Gholamreza
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Journal of Pharmaceutical Sciences
Texto Completo: https://www.revistas.usp.br/bjps/article/view/153790
Resumo: The aim of this study was to evaluate anti-hypoxia activity of polyphenolic extracts of Crataegus microphylla and Crataegus pentaegyn on mice. Three experimental models of hypoxia were considered, including asphyctic hypoxia, haemic hypoxia, and circulatory hypoxia. Polyphenolic extract of both plants exhibited significant anti-hypoxic activity and prolonged animal survival time. Anti-hypoia activity of C. pentaegyn was found to be superior to that of C. microphylla in circulatory and asphyctic hypoxia. Antihypoxic activity of these extracts may be attributed to their phenolic compounds.
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spelling Antihypoxic activities of Crataegus pentaegyn and Crataegus microphylla fruits-an in vivo assayCrataegus pentaegynaCrataegus microphyllaAntihypoxia/evaluationCirculatory hypoxiaThe aim of this study was to evaluate anti-hypoxia activity of polyphenolic extracts of Crataegus microphylla and Crataegus pentaegyn on mice. Three experimental models of hypoxia were considered, including asphyctic hypoxia, haemic hypoxia, and circulatory hypoxia. Polyphenolic extract of both plants exhibited significant anti-hypoxic activity and prolonged animal survival time. Anti-hypoia activity of C. pentaegyn was found to be superior to that of C. microphylla in circulatory and asphyctic hypoxia. Antihypoxic activity of these extracts may be attributed to their phenolic compounds.Universidade de São Paulo. Faculdade de Ciências Farmacêuticas2018-07-26info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/bjps/article/view/15379010.1590/s2175-97902018000217363Brazilian Journal of Pharmaceutical Sciences; Vol. 54 Núm. 2 (2018); e17363Brazilian Journal of Pharmaceutical Sciences; v. 54 n. 2 (2018); e17363Brazilian Journal of Pharmaceutical Sciences; Vol. 54 No. 2 (2018); e173632175-97901984-8250reponame:Brazilian Journal of Pharmaceutical Sciencesinstname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/bjps/article/view/153790/150178Copyright (c) 2018 Brazilian Journal of Pharmaceutical Sciences (Impresso)info:eu-repo/semantics/openAccessEbrahimzadeh, Mohammad AliKhalili, MasoumehJafari, NegarZareh, GitiFarzin, DavoodAmin, Gholamreza2019-03-17T13:50:40Zoai:revistas.usp.br:article/153790Revistahttps://www.revistas.usp.br/bjps/indexPUBhttps://old.scielo.br/oai/scielo-oai.phpbjps@usp.br||elizabeth.igne@gmail.com2175-97901984-8250opendoar:2019-03-17T13:50:40Brazilian Journal of Pharmaceutical Sciences - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv Antihypoxic activities of Crataegus pentaegyn and Crataegus microphylla fruits-an in vivo assay
title Antihypoxic activities of Crataegus pentaegyn and Crataegus microphylla fruits-an in vivo assay
spellingShingle Antihypoxic activities of Crataegus pentaegyn and Crataegus microphylla fruits-an in vivo assay
Ebrahimzadeh, Mohammad Ali
Crataegus pentaegyna
Crataegus microphylla
Antihypoxia/evaluation
Circulatory hypoxia
title_short Antihypoxic activities of Crataegus pentaegyn and Crataegus microphylla fruits-an in vivo assay
title_full Antihypoxic activities of Crataegus pentaegyn and Crataegus microphylla fruits-an in vivo assay
title_fullStr Antihypoxic activities of Crataegus pentaegyn and Crataegus microphylla fruits-an in vivo assay
title_full_unstemmed Antihypoxic activities of Crataegus pentaegyn and Crataegus microphylla fruits-an in vivo assay
title_sort Antihypoxic activities of Crataegus pentaegyn and Crataegus microphylla fruits-an in vivo assay
author Ebrahimzadeh, Mohammad Ali
author_facet Ebrahimzadeh, Mohammad Ali
Khalili, Masoumeh
Jafari, Negar
Zareh, Giti
Farzin, Davood
Amin, Gholamreza
author_role author
author2 Khalili, Masoumeh
Jafari, Negar
Zareh, Giti
Farzin, Davood
Amin, Gholamreza
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Ebrahimzadeh, Mohammad Ali
Khalili, Masoumeh
Jafari, Negar
Zareh, Giti
Farzin, Davood
Amin, Gholamreza
dc.subject.por.fl_str_mv Crataegus pentaegyna
Crataegus microphylla
Antihypoxia/evaluation
Circulatory hypoxia
topic Crataegus pentaegyna
Crataegus microphylla
Antihypoxia/evaluation
Circulatory hypoxia
description The aim of this study was to evaluate anti-hypoxia activity of polyphenolic extracts of Crataegus microphylla and Crataegus pentaegyn on mice. Three experimental models of hypoxia were considered, including asphyctic hypoxia, haemic hypoxia, and circulatory hypoxia. Polyphenolic extract of both plants exhibited significant anti-hypoxic activity and prolonged animal survival time. Anti-hypoia activity of C. pentaegyn was found to be superior to that of C. microphylla in circulatory and asphyctic hypoxia. Antihypoxic activity of these extracts may be attributed to their phenolic compounds.
publishDate 2018
dc.date.none.fl_str_mv 2018-07-26
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/bjps/article/view/153790
10.1590/s2175-97902018000217363
url https://www.revistas.usp.br/bjps/article/view/153790
identifier_str_mv 10.1590/s2175-97902018000217363
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.revistas.usp.br/bjps/article/view/153790/150178
dc.rights.driver.fl_str_mv Copyright (c) 2018 Brazilian Journal of Pharmaceutical Sciences (Impresso)
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2018 Brazilian Journal of Pharmaceutical Sciences (Impresso)
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Ciências Farmacêuticas
publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Ciências Farmacêuticas
dc.source.none.fl_str_mv Brazilian Journal of Pharmaceutical Sciences; Vol. 54 Núm. 2 (2018); e17363
Brazilian Journal of Pharmaceutical Sciences; v. 54 n. 2 (2018); e17363
Brazilian Journal of Pharmaceutical Sciences; Vol. 54 No. 2 (2018); e17363
2175-9790
1984-8250
reponame:Brazilian Journal of Pharmaceutical Sciences
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Brazilian Journal of Pharmaceutical Sciences
collection Brazilian Journal of Pharmaceutical Sciences
repository.name.fl_str_mv Brazilian Journal of Pharmaceutical Sciences - Universidade de São Paulo (USP)
repository.mail.fl_str_mv bjps@usp.br||elizabeth.igne@gmail.com
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