The evaluation of anesthetic associations: atropine/s-ketamine/xylazine and acepromazine/ketamine-s/midazolam in domestic felines (Felis domestica)
Autor(a) principal: | |
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Data de Publicação: | 2005 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Brazilian Journal of Veterinary Research and Animal Science |
Texto Completo: | https://www.revistas.usp.br/bjvras/article/view/26439 |
Resumo: | With the purpose to evaluate the anesthetic associations of atropine/s-ketamine/xylazine and acepromazine/s-ketamine/midazolam in domestic felines (Felis catus), 16 healthy males felines, submitted by their owners, were used. The animals were assisted at the Veterinary Hospital of the Superior School of Agriculture of Mossoró. The felines were distributed randomly into two groups, each one with eight animals, where a different anesthetic treatment was used. Group I was pretreated with atropine sulfate (0.044mg/kg) by a subcutaneous way, and elapsed 15 minutes, received xilazine (1.0mg/kg) associated with the s-ketamine (10mg/kg) through the intramuscular way. In the Group II, acepromazine (0.2 mg/kg) was used and after 15 minutes it was administered an association of midazolam (0.5mg/kg) and s-ketamine (10mg/kg), through the intramuscular way. Physiologic variables as: heart frequency, breathing frequency, saturation of oxygen and time of capillary completion, were appraised. The gauging of the variables was accomplished every 10 minutes, during 90 minutes. The periods of latency and analgesia as well the recovery were also evaluated. In the Group I, the mean of the latency period, after atropine/s-ketamine/xilazine administration was of 3.68min, while with the acepromazine/s-ketamine/midazolam it was of 3.95min. In the Group I, the average of the analgesia time was of 45.94min, and in the Group II the analgesia was determined in just one animal. The average of the recovery time in the Group I was of 134.08min and in the Group II, 78.28min. It was concluded that the association of atropine/s-ketamine/xilazine, produces an anesthesia of good quality in small surgical procedures, while the association acepromazine/s-ketamine/midazolam should be used for ambulatory small procedures. Both associations' present pharmacological properties comparable with those obtained with the racemic ketamine. |
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Brazilian Journal of Veterinary Research and Animal Science |
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The evaluation of anesthetic associations: atropine/s-ketamine/xylazine and acepromazine/ketamine-s/midazolam in domestic felines (Felis domestica)Avaliação das associações anestésicas: atropina/cetamina-s/xilazina e acepromazina/cetamina-s/midazolam em felinos domésticos (Felis domestica)Cetamina-SAnestesiologiaFelinos domésticos (Felis domestica)Ketamine-SAnesthesiologyFelinesWith the purpose to evaluate the anesthetic associations of atropine/s-ketamine/xylazine and acepromazine/s-ketamine/midazolam in domestic felines (Felis catus), 16 healthy males felines, submitted by their owners, were used. The animals were assisted at the Veterinary Hospital of the Superior School of Agriculture of Mossoró. The felines were distributed randomly into two groups, each one with eight animals, where a different anesthetic treatment was used. Group I was pretreated with atropine sulfate (0.044mg/kg) by a subcutaneous way, and elapsed 15 minutes, received xilazine (1.0mg/kg) associated with the s-ketamine (10mg/kg) through the intramuscular way. In the Group II, acepromazine (0.2 mg/kg) was used and after 15 minutes it was administered an association of midazolam (0.5mg/kg) and s-ketamine (10mg/kg), through the intramuscular way. Physiologic variables as: heart frequency, breathing frequency, saturation of oxygen and time of capillary completion, were appraised. The gauging of the variables was accomplished every 10 minutes, during 90 minutes. The periods of latency and analgesia as well the recovery were also evaluated. In the Group I, the mean of the latency period, after atropine/s-ketamine/xilazine administration was of 3.68min, while with the acepromazine/s-ketamine/midazolam it was of 3.95min. In the Group I, the average of the analgesia time was of 45.94min, and in the Group II the analgesia was determined in just one animal. The average of the recovery time in the Group I was of 134.08min and in the Group II, 78.28min. It was concluded that the association of atropine/s-ketamine/xilazine, produces an anesthesia of good quality in small surgical procedures, while the association acepromazine/s-ketamine/midazolam should be used for ambulatory small procedures. Both associations' present pharmacological properties comparable with those obtained with the racemic ketamine.Com o objetivo de avaliar as associações anestésicas atropina/cetamina-s/xilazina e acepromazina/cetamina-s/midazolam em felinos domésticos (Felis catus), foram utilizados 16 felinos, machos, hígidos cedidos por proprietários atendidos no Hospital Veterinário da Escola Superior de Agricultura de Mossoró. Os animais foram distribuídos aleatoriamente em dois grupos de oito animais, onde foi utilizado um tratamento anestésico distinto para cada grupo. O grupo I, foi pré-tratado com sulfato de atropina (0,044mg/kg) por via subcutânea, e decorridos 15 minutos, recebeu xilazina (1,0 mg/kg) associada a cetamina-s (10mg/kg) por via intramuscular. No grupo II, foi utilizada acepromazina (0,2 mg/kg) por via intramuscular e após 15 minutos, administrou-se a associação de midazolam (0,5mg/kg) e cetamina-s (10 mg/kg) por via intramuscular. Foram avaliadas as variáveis fisiológicas: freqüência cardíaca, freqüência respiratória, saturação de oxigênio e tempo de preenchimento capilar. A aferição das variáveis foi realizada a cada 10 minutos, durante 90 minutos. Também foi avaliado o período de latência, período de analgesia e de recuperação. A média do período de latência após a administração de atropina/cetamina-s/xilazina foi de 3,68min, enquanto na acepromazina/cetamina-s/midazolam foi de 3,95 min. No grupo I, a média do tempo de analgesia foi de 45,94min, e no grupo II foi obtida analgesia em apenas um animal. A média do tempo de recuperação no grupo I foi de 134, 08min e no grupo II, 78,28min. Concluiu-se que a associação atropina/cetamina-s/xilazina, produz uma anestesia de boa qualidade para pequenos procedimentos cirúrgicos, enquanto que a associação acepromazina/cetamina-s/midazolam deve ser utilizada para pequenos procedimentos ambulatoriais. Ambas associações apresentam propriedades farmacológicas comparáveis com as obtidas com a cetamina racêmica.Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia2005-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/bjvras/article/view/2643910.11606/issn.1678-4456.bjvras.2005.26439Brazilian Journal of Veterinary Research and Animal Science; Vol. 42 Núm. 2 (2005); 98-104Brazilian Journal of Veterinary Research and Animal Science; Vol. 42 No. 2 (2005); 98-104Brazilian Journal of Veterinary Research and Animal Science; v. 42 n. 2 (2005); 98-104Brazilian Journal of Veterinary Research and Animal Science; V. 42 N. 2 (2005); 98-1041678-44561413-9596reponame:Brazilian Journal of Veterinary Research and Animal Scienceinstname:Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP)instacron:USPporhttps://www.revistas.usp.br/bjvras/article/view/26439/28222Morais, Marco César Batista dePaula, Valéria Veras deAlves Júnior, Raimundo Barrêtoinfo:eu-repo/semantics/openAccess2020-06-23T04:20:25Zoai:revistas.usp.br:article/26439Revistahttps://www.revistas.usp.br/bjvrasPUBhttps://www.revistas.usp.br/bjvras/oaibjvras@usp.br1413-95961413-9596opendoar:https://www.revistas.usp.br/bjvras/index2023-01-12T16:42:43.680204Brazilian Journal of Veterinary Research and Animal Science - Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP)false |
dc.title.none.fl_str_mv |
The evaluation of anesthetic associations: atropine/s-ketamine/xylazine and acepromazine/ketamine-s/midazolam in domestic felines (Felis domestica) Avaliação das associações anestésicas: atropina/cetamina-s/xilazina e acepromazina/cetamina-s/midazolam em felinos domésticos (Felis domestica) |
title |
The evaluation of anesthetic associations: atropine/s-ketamine/xylazine and acepromazine/ketamine-s/midazolam in domestic felines (Felis domestica) |
spellingShingle |
The evaluation of anesthetic associations: atropine/s-ketamine/xylazine and acepromazine/ketamine-s/midazolam in domestic felines (Felis domestica) Morais, Marco César Batista de Cetamina-S Anestesiologia Felinos domésticos (Felis domestica) Ketamine-S Anesthesiology Felines |
title_short |
The evaluation of anesthetic associations: atropine/s-ketamine/xylazine and acepromazine/ketamine-s/midazolam in domestic felines (Felis domestica) |
title_full |
The evaluation of anesthetic associations: atropine/s-ketamine/xylazine and acepromazine/ketamine-s/midazolam in domestic felines (Felis domestica) |
title_fullStr |
The evaluation of anesthetic associations: atropine/s-ketamine/xylazine and acepromazine/ketamine-s/midazolam in domestic felines (Felis domestica) |
title_full_unstemmed |
The evaluation of anesthetic associations: atropine/s-ketamine/xylazine and acepromazine/ketamine-s/midazolam in domestic felines (Felis domestica) |
title_sort |
The evaluation of anesthetic associations: atropine/s-ketamine/xylazine and acepromazine/ketamine-s/midazolam in domestic felines (Felis domestica) |
author |
Morais, Marco César Batista de |
author_facet |
Morais, Marco César Batista de Paula, Valéria Veras de Alves Júnior, Raimundo Barrêto |
author_role |
author |
author2 |
Paula, Valéria Veras de Alves Júnior, Raimundo Barrêto |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Morais, Marco César Batista de Paula, Valéria Veras de Alves Júnior, Raimundo Barrêto |
dc.subject.por.fl_str_mv |
Cetamina-S Anestesiologia Felinos domésticos (Felis domestica) Ketamine-S Anesthesiology Felines |
topic |
Cetamina-S Anestesiologia Felinos domésticos (Felis domestica) Ketamine-S Anesthesiology Felines |
description |
With the purpose to evaluate the anesthetic associations of atropine/s-ketamine/xylazine and acepromazine/s-ketamine/midazolam in domestic felines (Felis catus), 16 healthy males felines, submitted by their owners, were used. The animals were assisted at the Veterinary Hospital of the Superior School of Agriculture of Mossoró. The felines were distributed randomly into two groups, each one with eight animals, where a different anesthetic treatment was used. Group I was pretreated with atropine sulfate (0.044mg/kg) by a subcutaneous way, and elapsed 15 minutes, received xilazine (1.0mg/kg) associated with the s-ketamine (10mg/kg) through the intramuscular way. In the Group II, acepromazine (0.2 mg/kg) was used and after 15 minutes it was administered an association of midazolam (0.5mg/kg) and s-ketamine (10mg/kg), through the intramuscular way. Physiologic variables as: heart frequency, breathing frequency, saturation of oxygen and time of capillary completion, were appraised. The gauging of the variables was accomplished every 10 minutes, during 90 minutes. The periods of latency and analgesia as well the recovery were also evaluated. In the Group I, the mean of the latency period, after atropine/s-ketamine/xilazine administration was of 3.68min, while with the acepromazine/s-ketamine/midazolam it was of 3.95min. In the Group I, the average of the analgesia time was of 45.94min, and in the Group II the analgesia was determined in just one animal. The average of the recovery time in the Group I was of 134.08min and in the Group II, 78.28min. It was concluded that the association of atropine/s-ketamine/xilazine, produces an anesthesia of good quality in small surgical procedures, while the association acepromazine/s-ketamine/midazolam should be used for ambulatory small procedures. Both associations' present pharmacological properties comparable with those obtained with the racemic ketamine. |
publishDate |
2005 |
dc.date.none.fl_str_mv |
2005-04-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/bjvras/article/view/26439 10.11606/issn.1678-4456.bjvras.2005.26439 |
url |
https://www.revistas.usp.br/bjvras/article/view/26439 |
identifier_str_mv |
10.11606/issn.1678-4456.bjvras.2005.26439 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/bjvras/article/view/26439/28222 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia |
publisher.none.fl_str_mv |
Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia |
dc.source.none.fl_str_mv |
Brazilian Journal of Veterinary Research and Animal Science; Vol. 42 Núm. 2 (2005); 98-104 Brazilian Journal of Veterinary Research and Animal Science; Vol. 42 No. 2 (2005); 98-104 Brazilian Journal of Veterinary Research and Animal Science; v. 42 n. 2 (2005); 98-104 Brazilian Journal of Veterinary Research and Animal Science; V. 42 N. 2 (2005); 98-104 1678-4456 1413-9596 reponame:Brazilian Journal of Veterinary Research and Animal Science instname:Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP) instacron:USP |
instname_str |
Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP) |
instacron_str |
USP |
institution |
USP |
reponame_str |
Brazilian Journal of Veterinary Research and Animal Science |
collection |
Brazilian Journal of Veterinary Research and Animal Science |
repository.name.fl_str_mv |
Brazilian Journal of Veterinary Research and Animal Science - Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP) |
repository.mail.fl_str_mv |
bjvras@usp.br |
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1797051557587451904 |