Laboratory animal welfare: environmental enrichment shows positive effect on animal testing
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Journal of Veterinary Research and Animal Science |
Texto Completo: | https://www.revistas.usp.br/bjvras/article/view/145008 |
Resumo: | Reproductive and developmental toxicology has focused on the need to approach the effects of organism exposure to various drugs during pregnancy after the mid-50’s, when the thalidomide tragedy stroke humanity. In recent decades, this area of study has developed a lot due to animal testing, raising awareness on the need to improve the quality of life of such animals. Therefore, this paper aims to investigate how the science of animal welfare can improve scientific research as a whole, including the reproductive and developmental toxicology fields, by emphasizing environmental enrichment in animal facilities. To do so, we conducted an integrative literature review on several quantitative and qualitative methodological approaches that are applicable to toxicology studies. Here, we present evidence that environmental enrichment improves animal welfare and prevents or reduces the negative effects of captive housing, which must be a principle of toxicological research for ethical, legal and scientific reasons. |
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USP-49 |
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Brazilian Journal of Veterinary Research and Animal Science |
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https://www.revistas.usp.br/bjvras/index |
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Laboratory animal welfare: environmental enrichment shows positive effect on animal testingBem-estar animal em laboratório: enriquecimento ambiental apresenta efeito positivo na experimentação animalAnimal welfareAnimal testingLaboratory animalReproductive toxicologyEnvironmental enrichmentBem-estar animalExperimentação animalAnimal de laboratórioToxicologia da reproduçãoEnriquecimento ambientalReproductive and developmental toxicology has focused on the need to approach the effects of organism exposure to various drugs during pregnancy after the mid-50’s, when the thalidomide tragedy stroke humanity. In recent decades, this area of study has developed a lot due to animal testing, raising awareness on the need to improve the quality of life of such animals. Therefore, this paper aims to investigate how the science of animal welfare can improve scientific research as a whole, including the reproductive and developmental toxicology fields, by emphasizing environmental enrichment in animal facilities. To do so, we conducted an integrative literature review on several quantitative and qualitative methodological approaches that are applicable to toxicology studies. Here, we present evidence that environmental enrichment improves animal welfare and prevents or reduces the negative effects of captive housing, which must be a principle of toxicological research for ethical, legal and scientific reasons.Na toxicologia da reprodução e do desenvolvimento, a atenção necessária foi dada aos efeitos da exposição do organismo às inúmeras drogas durante o período gestacional somente após a metade dos anos 50, quando a tragédia da talidomida atingiu a humanidade. Assim, esta área alcançou desenvolvimento científico com a contribuição da experimentação animal nas últimas décadas. O uso de animais de laboratórios para a pesquisa científica expôs a necessidade de melhorar a qualidade de vida destas espécies. Portanto, este trabalho tem como objetivo investigar como a ciência do bem-estar animal pode melhorar a pesquisa científica como um todo, incluindo na área de toxicologia da reprodução e de desenvolvimento, enfatizando o enriquecimento ambiental em biotérios. Uma revisão integrativa de literatura foi realizada, incluindo abordagens quantitativas e qualitativas, quais podem ser aplicadas para estudos de toxicologia. Aqui, são mostradas evidências de que o enriquecimento ambiental melhora o bem-estar animal e previne ou reduz os efeitos negativos do cativeiro, qual deve um princípio da pesquisa toxicológica por razões éticas, argumentos legais e garantias científicas.Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia2019-03-20info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/bjvras/article/view/14500810.11606/issn.1678-4456.bjvras.2018.145008Brazilian Journal of Veterinary Research and Animal Science; Vol. 55 Núm. 4 (2018); e145008Brazilian Journal of Veterinary Research and Animal Science; Vol. 55 No. 4 (2018); e145008Brazilian Journal of Veterinary Research and Animal Science; v. 55 n. 4 (2018); e145008Brazilian Journal of Veterinary Research and Animal Science; V. 55 N. 4 (2018); e1450081678-44561413-9596reponame:Brazilian Journal of Veterinary Research and Animal Scienceinstname:Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP)instacron:USPenghttps://www.revistas.usp.br/bjvras/article/view/145008/151457Copyright (c) 2019 Brazilian Journal of Veterinary Research and Animal Scienceinfo:eu-repo/semantics/openAccessMassari, Catia Helena de Almeida LimaMartins, Nadini OliveiraJozala, Angela FaustinoGrotto, DeniseGerenutti, Marli2020-06-23T04:02:39Zoai:revistas.usp.br:article/145008Revistahttps://www.revistas.usp.br/bjvrasPUBhttps://www.revistas.usp.br/bjvras/oaibjvras@usp.br1413-95961413-9596opendoar:https://www.revistas.usp.br/bjvras/index2023-01-12T16:44:01.982588Brazilian Journal of Veterinary Research and Animal Science - Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP)false |
dc.title.none.fl_str_mv |
Laboratory animal welfare: environmental enrichment shows positive effect on animal testing Bem-estar animal em laboratório: enriquecimento ambiental apresenta efeito positivo na experimentação animal |
title |
Laboratory animal welfare: environmental enrichment shows positive effect on animal testing |
spellingShingle |
Laboratory animal welfare: environmental enrichment shows positive effect on animal testing Massari, Catia Helena de Almeida Lima Animal welfare Animal testing Laboratory animal Reproductive toxicology Environmental enrichment Bem-estar animal Experimentação animal Animal de laboratório Toxicologia da reprodução Enriquecimento ambiental |
title_short |
Laboratory animal welfare: environmental enrichment shows positive effect on animal testing |
title_full |
Laboratory animal welfare: environmental enrichment shows positive effect on animal testing |
title_fullStr |
Laboratory animal welfare: environmental enrichment shows positive effect on animal testing |
title_full_unstemmed |
Laboratory animal welfare: environmental enrichment shows positive effect on animal testing |
title_sort |
Laboratory animal welfare: environmental enrichment shows positive effect on animal testing |
author |
Massari, Catia Helena de Almeida Lima |
author_facet |
Massari, Catia Helena de Almeida Lima Martins, Nadini Oliveira Jozala, Angela Faustino Grotto, Denise Gerenutti, Marli |
author_role |
author |
author2 |
Martins, Nadini Oliveira Jozala, Angela Faustino Grotto, Denise Gerenutti, Marli |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Massari, Catia Helena de Almeida Lima Martins, Nadini Oliveira Jozala, Angela Faustino Grotto, Denise Gerenutti, Marli |
dc.subject.por.fl_str_mv |
Animal welfare Animal testing Laboratory animal Reproductive toxicology Environmental enrichment Bem-estar animal Experimentação animal Animal de laboratório Toxicologia da reprodução Enriquecimento ambiental |
topic |
Animal welfare Animal testing Laboratory animal Reproductive toxicology Environmental enrichment Bem-estar animal Experimentação animal Animal de laboratório Toxicologia da reprodução Enriquecimento ambiental |
description |
Reproductive and developmental toxicology has focused on the need to approach the effects of organism exposure to various drugs during pregnancy after the mid-50’s, when the thalidomide tragedy stroke humanity. In recent decades, this area of study has developed a lot due to animal testing, raising awareness on the need to improve the quality of life of such animals. Therefore, this paper aims to investigate how the science of animal welfare can improve scientific research as a whole, including the reproductive and developmental toxicology fields, by emphasizing environmental enrichment in animal facilities. To do so, we conducted an integrative literature review on several quantitative and qualitative methodological approaches that are applicable to toxicology studies. Here, we present evidence that environmental enrichment improves animal welfare and prevents or reduces the negative effects of captive housing, which must be a principle of toxicological research for ethical, legal and scientific reasons. |
publishDate |
2019 |
dc.date.none.fl_str_mv |
2019-03-20 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/bjvras/article/view/145008 10.11606/issn.1678-4456.bjvras.2018.145008 |
url |
https://www.revistas.usp.br/bjvras/article/view/145008 |
identifier_str_mv |
10.11606/issn.1678-4456.bjvras.2018.145008 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/bjvras/article/view/145008/151457 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2019 Brazilian Journal of Veterinary Research and Animal Science info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2019 Brazilian Journal of Veterinary Research and Animal Science |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia |
publisher.none.fl_str_mv |
Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia |
dc.source.none.fl_str_mv |
Brazilian Journal of Veterinary Research and Animal Science; Vol. 55 Núm. 4 (2018); e145008 Brazilian Journal of Veterinary Research and Animal Science; Vol. 55 No. 4 (2018); e145008 Brazilian Journal of Veterinary Research and Animal Science; v. 55 n. 4 (2018); e145008 Brazilian Journal of Veterinary Research and Animal Science; V. 55 N. 4 (2018); e145008 1678-4456 1413-9596 reponame:Brazilian Journal of Veterinary Research and Animal Science instname:Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP) instacron:USP |
instname_str |
Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP) |
instacron_str |
USP |
institution |
USP |
reponame_str |
Brazilian Journal of Veterinary Research and Animal Science |
collection |
Brazilian Journal of Veterinary Research and Animal Science |
repository.name.fl_str_mv |
Brazilian Journal of Veterinary Research and Animal Science - Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP) |
repository.mail.fl_str_mv |
bjvras@usp.br |
_version_ |
1797051567327674368 |