Use of horse pericardium preserved in glycerin as corneal graft in dogs. Experimental study
Autor(a) principal: | |
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Data de Publicação: | 1997 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Brazilian Journal of Veterinary Research and Animal Science |
Texto Completo: | https://www.revistas.usp.br/bjvras/article/view/50282 |
Resumo: | Repair of the cornea is a challenge to several researches. Cornea lesions have been treated by many different methods. The purpose of this paper was to study the use of horse preserved pericardium to repair dog cornea. Fifteen mixed breed dogs, male and female, 8 to 10 kg of body weight were used. After pre-surgical procedures, under general anesthesia, a fill-thickness piece of cornea of 5 x 4 mm was excised. A fragment of the same size of horse pericardium preserved in glycerin was sutured with7-0 prolen in single suture. Clinical examination revealed blefarospasm, cloudy cornea and flare that disappeared in two weeks. In the 9th day post-surgery, superficial vascularization and granulation tissue were observed over the graft and the suture. Opacity of the graft persisted until the end of observation period, when a very mild transparence was noted. Fluorescein stain was retained until the 36th day. Anterior chamber was deep all over the experimental period and pupils were symetrical. IOPwas initially low but raised to normal values. Acute inflammatory reaction and fibrosis could be seen hitologically. The graft was epithelized on the 36th day. On the 70th day, mild chronic inflammation and endothelization were observed and the site of the graft looked like a “sandwich” (epithelium - stroma - implant - stroma - epithelium). |
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Brazilian Journal of Veterinary Research and Animal Science |
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Use of horse pericardium preserved in glycerin as corneal graft in dogs. Experimental studyUso do pericárdio de eqüino conservado em glicerina como enxerto penetrante da córnea de cães. Estudo experimentalCórneaPericárdioEnxertosBiopróteseTransplante de córnea.CorneaBioprothesisPericardiumGraftsCorneal transplantationRepair of the cornea is a challenge to several researches. Cornea lesions have been treated by many different methods. The purpose of this paper was to study the use of horse preserved pericardium to repair dog cornea. Fifteen mixed breed dogs, male and female, 8 to 10 kg of body weight were used. After pre-surgical procedures, under general anesthesia, a fill-thickness piece of cornea of 5 x 4 mm was excised. A fragment of the same size of horse pericardium preserved in glycerin was sutured with7-0 prolen in single suture. Clinical examination revealed blefarospasm, cloudy cornea and flare that disappeared in two weeks. In the 9th day post-surgery, superficial vascularization and granulation tissue were observed over the graft and the suture. Opacity of the graft persisted until the end of observation period, when a very mild transparence was noted. Fluorescein stain was retained until the 36th day. Anterior chamber was deep all over the experimental period and pupils were symetrical. IOPwas initially low but raised to normal values. Acute inflammatory reaction and fibrosis could be seen hitologically. The graft was epithelized on the 36th day. On the 70th day, mild chronic inflammation and endothelization were observed and the site of the graft looked like a “sandwich” (epithelium - stroma - implant - stroma - epithelium).Com o objetivo de estudar o emprego do pericárdio de eqüino, conservado em glicerina, na reparação experimental de defeitos penetrantes da córnea de cães utilizaram-se 15 animais; mestiços, machos e fêmeas, pesando entre 8 e 10 kg. Uma lesão penetrante da córnea de 5 x 4 mm foi provocada e fragmento de pericárdio, de igual dimensão, foi suturado em pontos simples separados com Prolene 7-0. Os animais foram sacrificados nos tempos 2,7,15, 30 e 70 dias de pósoperatório. Os resultados obtidos, quando analisados, tanto do ponto de vista clínico quanto histológico, mostraram queo pericárdio de eqüino conservado apresentou-se como meio satisfatório de reparação penetrante de lesões da córnea de cães.Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia1997-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/bjvras/article/view/5028210.11606/issn.2318-3659.v34i3p138-141Brazilian Journal of Veterinary Research and Animal Science; Vol. 34 Núm. 3 (1997); 138-141Brazilian Journal of Veterinary Research and Animal Science; Vol. 34 No. 3 (1997); 138-141Brazilian Journal of Veterinary Research and Animal Science; v. 34 n. 3 (1997); 138-141Brazilian Journal of Veterinary Research and Animal Science; V. 34 N. 3 (1997); 138-1411678-44561413-9596reponame:Brazilian Journal of Veterinary Research and Animal Scienceinstname:Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP)instacron:USPporhttps://www.revistas.usp.br/bjvras/article/view/50282/54395Barros, Paulo Sergio de MoraesSafatle, Angélica Mendonça VazRigueiro, Moacyrinfo:eu-repo/semantics/openAccess2020-06-23T04:48:10Zoai:revistas.usp.br:article/50282Revistahttps://www.revistas.usp.br/bjvrasPUBhttps://www.revistas.usp.br/bjvras/oaibjvras@usp.br1413-95961413-9596opendoar:https://www.revistas.usp.br/bjvras/index2023-01-12T16:43:18.127580Brazilian Journal of Veterinary Research and Animal Science - Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP)false |
dc.title.none.fl_str_mv |
Use of horse pericardium preserved in glycerin as corneal graft in dogs. Experimental study Uso do pericárdio de eqüino conservado em glicerina como enxerto penetrante da córnea de cães. Estudo experimental |
title |
Use of horse pericardium preserved in glycerin as corneal graft in dogs. Experimental study |
spellingShingle |
Use of horse pericardium preserved in glycerin as corneal graft in dogs. Experimental study Barros, Paulo Sergio de Moraes Córnea Pericárdio Enxertos Bioprótese Transplante de córnea. Cornea Bioprothesis Pericardium Grafts Corneal transplantation |
title_short |
Use of horse pericardium preserved in glycerin as corneal graft in dogs. Experimental study |
title_full |
Use of horse pericardium preserved in glycerin as corneal graft in dogs. Experimental study |
title_fullStr |
Use of horse pericardium preserved in glycerin as corneal graft in dogs. Experimental study |
title_full_unstemmed |
Use of horse pericardium preserved in glycerin as corneal graft in dogs. Experimental study |
title_sort |
Use of horse pericardium preserved in glycerin as corneal graft in dogs. Experimental study |
author |
Barros, Paulo Sergio de Moraes |
author_facet |
Barros, Paulo Sergio de Moraes Safatle, Angélica Mendonça Vaz Rigueiro, Moacyr |
author_role |
author |
author2 |
Safatle, Angélica Mendonça Vaz Rigueiro, Moacyr |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Barros, Paulo Sergio de Moraes Safatle, Angélica Mendonça Vaz Rigueiro, Moacyr |
dc.subject.por.fl_str_mv |
Córnea Pericárdio Enxertos Bioprótese Transplante de córnea. Cornea Bioprothesis Pericardium Grafts Corneal transplantation |
topic |
Córnea Pericárdio Enxertos Bioprótese Transplante de córnea. Cornea Bioprothesis Pericardium Grafts Corneal transplantation |
description |
Repair of the cornea is a challenge to several researches. Cornea lesions have been treated by many different methods. The purpose of this paper was to study the use of horse preserved pericardium to repair dog cornea. Fifteen mixed breed dogs, male and female, 8 to 10 kg of body weight were used. After pre-surgical procedures, under general anesthesia, a fill-thickness piece of cornea of 5 x 4 mm was excised. A fragment of the same size of horse pericardium preserved in glycerin was sutured with7-0 prolen in single suture. Clinical examination revealed blefarospasm, cloudy cornea and flare that disappeared in two weeks. In the 9th day post-surgery, superficial vascularization and granulation tissue were observed over the graft and the suture. Opacity of the graft persisted until the end of observation period, when a very mild transparence was noted. Fluorescein stain was retained until the 36th day. Anterior chamber was deep all over the experimental period and pupils were symetrical. IOPwas initially low but raised to normal values. Acute inflammatory reaction and fibrosis could be seen hitologically. The graft was epithelized on the 36th day. On the 70th day, mild chronic inflammation and endothelization were observed and the site of the graft looked like a “sandwich” (epithelium - stroma - implant - stroma - epithelium). |
publishDate |
1997 |
dc.date.none.fl_str_mv |
1997-06-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/bjvras/article/view/50282 10.11606/issn.2318-3659.v34i3p138-141 |
url |
https://www.revistas.usp.br/bjvras/article/view/50282 |
identifier_str_mv |
10.11606/issn.2318-3659.v34i3p138-141 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/bjvras/article/view/50282/54395 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia |
publisher.none.fl_str_mv |
Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia |
dc.source.none.fl_str_mv |
Brazilian Journal of Veterinary Research and Animal Science; Vol. 34 Núm. 3 (1997); 138-141 Brazilian Journal of Veterinary Research and Animal Science; Vol. 34 No. 3 (1997); 138-141 Brazilian Journal of Veterinary Research and Animal Science; v. 34 n. 3 (1997); 138-141 Brazilian Journal of Veterinary Research and Animal Science; V. 34 N. 3 (1997); 138-141 1678-4456 1413-9596 reponame:Brazilian Journal of Veterinary Research and Animal Science instname:Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP) instacron:USP |
instname_str |
Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP) |
instacron_str |
USP |
institution |
USP |
reponame_str |
Brazilian Journal of Veterinary Research and Animal Science |
collection |
Brazilian Journal of Veterinary Research and Animal Science |
repository.name.fl_str_mv |
Brazilian Journal of Veterinary Research and Animal Science - Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP) |
repository.mail.fl_str_mv |
bjvras@usp.br |
_version_ |
1797051562720231424 |