Effects of therapeutic ultrasound on the hyperalgesia and edema in arthritic rats

Detalhes bibliográficos
Autor(a) principal: Pereira, Leani Souza Máximo
Data de Publicação: 1998
Outros Autores: Francischi, Janetti Nogueira de, Silva, Fabrícia Mendes Pereira e, Santos, Ândrea Marília Costa, Tiradentes, Kamile Almeida, Carmo, Simone Caldeira
Tipo de documento: Artigo
Idioma: por
Título da fonte: Fisioterapia e Pesquisa
Texto Completo: https://www.revistas.usp.br/fpusp/article/view/77289
Resumo: With the population aging, the prevalence of chronic diseases of muscles and joints restricting in the elderly functional capacity has been increasing. The rheumatoid arthritis is part of this group of pathologies and the treatment of the disease has been basically to reduce the symptoms as pain, edema, rigidity, muscular atrophies through the inhibition of the inflammatory process. For this, treatments with drugs and treatment with physical therapeutics resources are used. The ultrasound is a physical therapeutic resource that has been used thoroughly in the clinical practice with the objective of solving the inflammatory process of the rheumatoid arthritis. The effect of the ultra-sound was observed on the edema and on the hyperalgesia of the posterior paws of arthritic rats. The rheumatoid arthritis was induced through an injection of an emulsion oil-water contends 400 ?g of Micobacierium butiricum. The hyperalgesia was detected in the 11 st day and the edema in the 12nd day after the induction of the rheumatoid arthritis. For comparative study, it was administered the indometacina orally in the dose of 0,5 mg/kg/dia during 15 days where we didn't observe reduction of the hyperalgesia but there was reduction of the edema of the posterior paws of the arthritic rats. The ultrasound in the frequency of 1 MHz. intensity 0,2 watts/cm2, for 5 minutes, for 15 days didn't reduce the hyperalgesia or edema of the posterior paws of the arthritic rats. The association of the ultrasound with the indomethacin in the doses already mentioned previously got to inhibit the hyperalgesia and edema of the posterior paws of the arthritic rats significantly.
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spelling Effects of therapeutic ultrasound on the hyperalgesia and edema in arthritic ratsOs efeitos do ultra-som na hyperalgesia e no edema de ratos artríticosTerapia por ultrassommétodosEnvelhecimentoFisioterapiareabilitaçãoHiperalgesiaArtriteEdemasUltrasonic therapymethodsAgingPhysical therapyreabilitaçãoHyperalgesiaArthritis rheumatoidrehabilitationEdemaWith the population aging, the prevalence of chronic diseases of muscles and joints restricting in the elderly functional capacity has been increasing. The rheumatoid arthritis is part of this group of pathologies and the treatment of the disease has been basically to reduce the symptoms as pain, edema, rigidity, muscular atrophies through the inhibition of the inflammatory process. For this, treatments with drugs and treatment with physical therapeutics resources are used. The ultrasound is a physical therapeutic resource that has been used thoroughly in the clinical practice with the objective of solving the inflammatory process of the rheumatoid arthritis. The effect of the ultra-sound was observed on the edema and on the hyperalgesia of the posterior paws of arthritic rats. The rheumatoid arthritis was induced through an injection of an emulsion oil-water contends 400 ?g of Micobacierium butiricum. The hyperalgesia was detected in the 11 st day and the edema in the 12nd day after the induction of the rheumatoid arthritis. For comparative study, it was administered the indometacina orally in the dose of 0,5 mg/kg/dia during 15 days where we didn't observe reduction of the hyperalgesia but there was reduction of the edema of the posterior paws of the arthritic rats. The ultrasound in the frequency of 1 MHz. intensity 0,2 watts/cm2, for 5 minutes, for 15 days didn't reduce the hyperalgesia or edema of the posterior paws of the arthritic rats. The association of the ultrasound with the indomethacin in the doses already mentioned previously got to inhibit the hyperalgesia and edema of the posterior paws of the arthritic rats significantly.Com o envelhecimento populacional a prevalência de doenças osteomusculares crônicas, que restringem a capacidade funcional dos idosos tem aumentado. A artrite reumatóide, integrante desse grupo de patologias, tem atualmente a sua abordagem terapêutica realizada através dô medicamentos e de fisioterapia. Os tratamentos propostos consistem basicamente em reduzir os sintomas apresentados pela doença tais como: a dor, o edema, a rigidez e a atrofia muscular, através da inibição do processo inflamatórip. Foi observado o efeito do ultra-som no edema e na hiperalgesia das patas posteriores de ratos artríticos. A artrite reumatóide foi induzida experimentalmente através de uma injeção de uma emulsão óleo-água contendo 400 ug de Micobacterium butiricum. A hiperalgesia foi detectada no 1 I o dia e o edema no 12° dia após a indução da artrite. O ultra-som com uma freqüência de 1 MHz, intensidade de 0,2 watts/cm2 , aplicado por 5 minutos diariamente durante 15 dias, não reduziu a hiperalgesia ou p edema das patas posteriores dos ratos artríticos. Para estudo comparativo, foi administrado um antiinflamatório não-esteróide, a indometacina, por via oral na dose de 0,5 mg/kg/dia durante 15 dias consecutivos onde não foi observado a redução da hiperalgesia, mas ocorreu a redução do edema. A associação do ultra-som com a indometacina, nas doses j á citadas anteriormente, conseguiu inibir significativamente a hiperalgesia e o edema das patas dos ratos artríticos. Em nossos estudos, concluímos que o ultra-som associado à indometacina foi mais efetivo do que quando a indometacina ou ultra-som foram utilizados isoladamente na inibição da hiperalgesia e no edema de ratos artríticos.Universidade de São Paulo. Faculdade de Medicina1998-12-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/fpusp/article/view/7728910.1590/fpusp.v5i2.77289Fisioterapia e Pesquisa; Vol. 5 No. 2 (1998); 83-96Fisioterapia e Pesquisa; Vol. 5 Núm. 2 (1998); 83-96Fisioterapia e Pesquisa; v. 5 n. 2 (1998); 83-962316-91171809-2950reponame:Fisioterapia e Pesquisainstname:Universidade de São Paulo (USP)instacron:USPporhttps://www.revistas.usp.br/fpusp/article/view/77289/81156Copyright (c) 2017 Fisioterapia e Pesquisainfo:eu-repo/semantics/openAccessPereira, Leani Souza MáximoFrancischi, Janetti Nogueira deSilva, Fabrícia Mendes Pereira eSantos, Ândrea Marília CostaTiradentes, Kamile AlmeidaCarmo, Simone Caldeira2014-05-07T22:47:47Zoai:revistas.usp.br:article/77289Revistahttp://www.revistas.usp.br/fpuspPUBhttps://www.revistas.usp.br/fpusp/oai||revfisio@usp.br2316-91171809-2950opendoar:2014-05-07T22:47:47Fisioterapia e Pesquisa - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv Effects of therapeutic ultrasound on the hyperalgesia and edema in arthritic rats
Os efeitos do ultra-som na hyperalgesia e no edema de ratos artríticos
title Effects of therapeutic ultrasound on the hyperalgesia and edema in arthritic rats
spellingShingle Effects of therapeutic ultrasound on the hyperalgesia and edema in arthritic rats
Pereira, Leani Souza Máximo
Terapia por ultrassom
métodos
Envelhecimento
Fisioterapia
reabilitação
Hiperalgesia
Artrite
Edemas
Ultrasonic therapy
methods
Aging
Physical therapy
reabilitação
Hyperalgesia
Arthritis rheumatoid
rehabilitation
Edema
title_short Effects of therapeutic ultrasound on the hyperalgesia and edema in arthritic rats
title_full Effects of therapeutic ultrasound on the hyperalgesia and edema in arthritic rats
title_fullStr Effects of therapeutic ultrasound on the hyperalgesia and edema in arthritic rats
title_full_unstemmed Effects of therapeutic ultrasound on the hyperalgesia and edema in arthritic rats
title_sort Effects of therapeutic ultrasound on the hyperalgesia and edema in arthritic rats
author Pereira, Leani Souza Máximo
author_facet Pereira, Leani Souza Máximo
Francischi, Janetti Nogueira de
Silva, Fabrícia Mendes Pereira e
Santos, Ândrea Marília Costa
Tiradentes, Kamile Almeida
Carmo, Simone Caldeira
author_role author
author2 Francischi, Janetti Nogueira de
Silva, Fabrícia Mendes Pereira e
Santos, Ândrea Marília Costa
Tiradentes, Kamile Almeida
Carmo, Simone Caldeira
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Pereira, Leani Souza Máximo
Francischi, Janetti Nogueira de
Silva, Fabrícia Mendes Pereira e
Santos, Ândrea Marília Costa
Tiradentes, Kamile Almeida
Carmo, Simone Caldeira
dc.subject.por.fl_str_mv Terapia por ultrassom
métodos
Envelhecimento
Fisioterapia
reabilitação
Hiperalgesia
Artrite
Edemas
Ultrasonic therapy
methods
Aging
Physical therapy
reabilitação
Hyperalgesia
Arthritis rheumatoid
rehabilitation
Edema
topic Terapia por ultrassom
métodos
Envelhecimento
Fisioterapia
reabilitação
Hiperalgesia
Artrite
Edemas
Ultrasonic therapy
methods
Aging
Physical therapy
reabilitação
Hyperalgesia
Arthritis rheumatoid
rehabilitation
Edema
description With the population aging, the prevalence of chronic diseases of muscles and joints restricting in the elderly functional capacity has been increasing. The rheumatoid arthritis is part of this group of pathologies and the treatment of the disease has been basically to reduce the symptoms as pain, edema, rigidity, muscular atrophies through the inhibition of the inflammatory process. For this, treatments with drugs and treatment with physical therapeutics resources are used. The ultrasound is a physical therapeutic resource that has been used thoroughly in the clinical practice with the objective of solving the inflammatory process of the rheumatoid arthritis. The effect of the ultra-sound was observed on the edema and on the hyperalgesia of the posterior paws of arthritic rats. The rheumatoid arthritis was induced through an injection of an emulsion oil-water contends 400 ?g of Micobacierium butiricum. The hyperalgesia was detected in the 11 st day and the edema in the 12nd day after the induction of the rheumatoid arthritis. For comparative study, it was administered the indometacina orally in the dose of 0,5 mg/kg/dia during 15 days where we didn't observe reduction of the hyperalgesia but there was reduction of the edema of the posterior paws of the arthritic rats. The ultrasound in the frequency of 1 MHz. intensity 0,2 watts/cm2, for 5 minutes, for 15 days didn't reduce the hyperalgesia or edema of the posterior paws of the arthritic rats. The association of the ultrasound with the indomethacin in the doses already mentioned previously got to inhibit the hyperalgesia and edema of the posterior paws of the arthritic rats significantly.
publishDate 1998
dc.date.none.fl_str_mv 1998-12-07
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/fpusp/article/view/77289
10.1590/fpusp.v5i2.77289
url https://www.revistas.usp.br/fpusp/article/view/77289
identifier_str_mv 10.1590/fpusp.v5i2.77289
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://www.revistas.usp.br/fpusp/article/view/77289/81156
dc.rights.driver.fl_str_mv Copyright (c) 2017 Fisioterapia e Pesquisa
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2017 Fisioterapia e Pesquisa
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Medicina
publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Medicina
dc.source.none.fl_str_mv Fisioterapia e Pesquisa; Vol. 5 No. 2 (1998); 83-96
Fisioterapia e Pesquisa; Vol. 5 Núm. 2 (1998); 83-96
Fisioterapia e Pesquisa; v. 5 n. 2 (1998); 83-96
2316-9117
1809-2950
reponame:Fisioterapia e Pesquisa
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Fisioterapia e Pesquisa
collection Fisioterapia e Pesquisa
repository.name.fl_str_mv Fisioterapia e Pesquisa - Universidade de São Paulo (USP)
repository.mail.fl_str_mv ||revfisio@usp.br
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