Longitudinal analysis of verbal episodic memory in patients with relapsing-remitting multiple sclerosis

Bibliographic Details
Main Author: Boa,Izadora Nogueira Fonte
Publication Date: 2018
Other Authors: Rimkus,Carolina de Medeiros, Campanholo,Kenia Repiso, Pereira,Samira Luisa Apóstolos, Junqueira,Thiago de Faria, Machado,Melissa de Almeida Rodrigues, Callegaro,Dagoberto, Otaduy,Maria Concepción García, Leite,Claudia da Costa, Miotto,Eliane Correa
Format: Article
Language: eng
Source: Arquivos de neuro-psiquiatria (Online)
Download full: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2018000500302
Summary: ABSTRACT Objective: A 4.5-year follow-up study was conducted to characterize baseline verbal episodic memory (VEM) and its behavior and to assess the effects of relapsing-remitting multiple sclerosis (RRMS) on this domain. Methods: Twenty-nine patients with RRMS underwent two neuropsychological assessments performed an average of 4.5 years apart. Twenty-six control participants underwent a single neuropsychological assessment. A significance level of p < 0.005 was adopted to denote a significant difference between the groups on the Mann Whitney and Wilcoxon paired statistical analyses. Results: No statistical difference was found in the results of the VEM tests between the first and second neuropsychological assessments of the patients. However, a statistical difference was evident between the patient and control groups in the results of the VEM tests. Conclusion: The patient group showed changes in the VEM relative to the control group. After approximately 4.5 years of disease, the patient performance on the VEM stabilized or improved.
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spelling Longitudinal analysis of verbal episodic memory in patients with relapsing-remitting multiple sclerosismultiple sclerosiscognitionlongitudinal studiesABSTRACT Objective: A 4.5-year follow-up study was conducted to characterize baseline verbal episodic memory (VEM) and its behavior and to assess the effects of relapsing-remitting multiple sclerosis (RRMS) on this domain. Methods: Twenty-nine patients with RRMS underwent two neuropsychological assessments performed an average of 4.5 years apart. Twenty-six control participants underwent a single neuropsychological assessment. A significance level of p < 0.005 was adopted to denote a significant difference between the groups on the Mann Whitney and Wilcoxon paired statistical analyses. Results: No statistical difference was found in the results of the VEM tests between the first and second neuropsychological assessments of the patients. However, a statistical difference was evident between the patient and control groups in the results of the VEM tests. Conclusion: The patient group showed changes in the VEM relative to the control group. After approximately 4.5 years of disease, the patient performance on the VEM stabilized or improved.Academia Brasileira de Neurologia - ABNEURO2018-05-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2018000500302Arquivos de Neuro-Psiquiatria v.76 n.5 2018reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/0004-282x20180038info:eu-repo/semantics/openAccessBoa,Izadora Nogueira FonteRimkus,Carolina de MedeirosCampanholo,Kenia RepisoPereira,Samira Luisa ApóstolosJunqueira,Thiago de FariaMachado,Melissa de Almeida RodriguesCallegaro,DagobertoOtaduy,Maria Concepción GarcíaLeite,Claudia da CostaMiotto,Eliane Correaeng2018-05-25T00:00:00Zoai:scielo:S0004-282X2018000500302Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2018-05-25T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse
dc.title.none.fl_str_mv Longitudinal analysis of verbal episodic memory in patients with relapsing-remitting multiple sclerosis
title Longitudinal analysis of verbal episodic memory in patients with relapsing-remitting multiple sclerosis
spellingShingle Longitudinal analysis of verbal episodic memory in patients with relapsing-remitting multiple sclerosis
Boa,Izadora Nogueira Fonte
multiple sclerosis
cognition
longitudinal studies
title_short Longitudinal analysis of verbal episodic memory in patients with relapsing-remitting multiple sclerosis
title_full Longitudinal analysis of verbal episodic memory in patients with relapsing-remitting multiple sclerosis
title_fullStr Longitudinal analysis of verbal episodic memory in patients with relapsing-remitting multiple sclerosis
title_full_unstemmed Longitudinal analysis of verbal episodic memory in patients with relapsing-remitting multiple sclerosis
title_sort Longitudinal analysis of verbal episodic memory in patients with relapsing-remitting multiple sclerosis
author Boa,Izadora Nogueira Fonte
author_facet Boa,Izadora Nogueira Fonte
Rimkus,Carolina de Medeiros
Campanholo,Kenia Repiso
Pereira,Samira Luisa Apóstolos
Junqueira,Thiago de Faria
Machado,Melissa de Almeida Rodrigues
Callegaro,Dagoberto
Otaduy,Maria Concepción García
Leite,Claudia da Costa
Miotto,Eliane Correa
author_role author
author2 Rimkus,Carolina de Medeiros
Campanholo,Kenia Repiso
Pereira,Samira Luisa Apóstolos
Junqueira,Thiago de Faria
Machado,Melissa de Almeida Rodrigues
Callegaro,Dagoberto
Otaduy,Maria Concepción García
Leite,Claudia da Costa
Miotto,Eliane Correa
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Boa,Izadora Nogueira Fonte
Rimkus,Carolina de Medeiros
Campanholo,Kenia Repiso
Pereira,Samira Luisa Apóstolos
Junqueira,Thiago de Faria
Machado,Melissa de Almeida Rodrigues
Callegaro,Dagoberto
Otaduy,Maria Concepción García
Leite,Claudia da Costa
Miotto,Eliane Correa
dc.subject.por.fl_str_mv multiple sclerosis
cognition
longitudinal studies
topic multiple sclerosis
cognition
longitudinal studies
description ABSTRACT Objective: A 4.5-year follow-up study was conducted to characterize baseline verbal episodic memory (VEM) and its behavior and to assess the effects of relapsing-remitting multiple sclerosis (RRMS) on this domain. Methods: Twenty-nine patients with RRMS underwent two neuropsychological assessments performed an average of 4.5 years apart. Twenty-six control participants underwent a single neuropsychological assessment. A significance level of p < 0.005 was adopted to denote a significant difference between the groups on the Mann Whitney and Wilcoxon paired statistical analyses. Results: No statistical difference was found in the results of the VEM tests between the first and second neuropsychological assessments of the patients. However, a statistical difference was evident between the patient and control groups in the results of the VEM tests. Conclusion: The patient group showed changes in the VEM relative to the control group. After approximately 4.5 years of disease, the patient performance on the VEM stabilized or improved.
publishDate 2018
dc.date.none.fl_str_mv 2018-05-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2018000500302
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2018000500302
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/0004-282x20180038
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
dc.source.none.fl_str_mv Arquivos de Neuro-Psiquiatria v.76 n.5 2018
reponame:Arquivos de neuro-psiquiatria (Online)
instname:Academia Brasileira de Neurologia
instacron:ABNEURO
instname_str Academia Brasileira de Neurologia
instacron_str ABNEURO
institution ABNEURO
reponame_str Arquivos de neuro-psiquiatria (Online)
collection Arquivos de neuro-psiquiatria (Online)
repository.name.fl_str_mv Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia
repository.mail.fl_str_mv ||revista.arquivos@abneuro.org
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