Muscle depletion in cirrhotic patients assessed using computed tomography: a cross-sectional study
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | São Paulo medical journal (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802020000200152 |
Resumo: | ABSTRACT BACKGROUND: Sarcopenia is a common complication in patients with cirrhosis and may lead to increased morbidity and mortality. OBJECTIVE: To investigate the prevalence of sarcopenia and its association with disease severity scores, among patients with cirrhosis. DESIGN AND SETTING: Observational and retrospective cohort study carried out in a tertiary-care hospital in southern Brazil. METHODS: This study was conducted among patients with chronic liver disease who were followed up at the gastroenterology and hepatology outpatient clinic of a tertiary-care hospital in southern Brazil and who underwent computed tomography scans of the abdomen through any indication. RESULTS: We included 83 patients in the study. In the population evaluated, there was a predominance of males (57.80%) and the mean age was 56 years. Hepatitis B or C virus was present in the genesis of the disease in 34.9% of the cases, followed by an etiology of alcohol abuse (30.1%). Sarcopenia was diagnosed in 41 (49.4%) of the patients when the cutoff point for cirrhotic patients was used. There was no significant correlation between the Child-Pugh and MELD severity scores and the occurrence of sarcopenia. CONCLUSION: Sarcopenia presents high prevalence among patients with chronic liver disease, without any association with predictors of severity. |
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São Paulo medical journal (Online) |
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Muscle depletion in cirrhotic patients assessed using computed tomography: a cross-sectional studyLiver cirrhosisSarcopeniaMortalityMalnutritionMuscle depletionCirrhosisChronic liver diseaseABSTRACT BACKGROUND: Sarcopenia is a common complication in patients with cirrhosis and may lead to increased morbidity and mortality. OBJECTIVE: To investigate the prevalence of sarcopenia and its association with disease severity scores, among patients with cirrhosis. DESIGN AND SETTING: Observational and retrospective cohort study carried out in a tertiary-care hospital in southern Brazil. METHODS: This study was conducted among patients with chronic liver disease who were followed up at the gastroenterology and hepatology outpatient clinic of a tertiary-care hospital in southern Brazil and who underwent computed tomography scans of the abdomen through any indication. RESULTS: We included 83 patients in the study. In the population evaluated, there was a predominance of males (57.80%) and the mean age was 56 years. Hepatitis B or C virus was present in the genesis of the disease in 34.9% of the cases, followed by an etiology of alcohol abuse (30.1%). Sarcopenia was diagnosed in 41 (49.4%) of the patients when the cutoff point for cirrhotic patients was used. There was no significant correlation between the Child-Pugh and MELD severity scores and the occurrence of sarcopenia. CONCLUSION: Sarcopenia presents high prevalence among patients with chronic liver disease, without any association with predictors of severity.Associação Paulista de Medicina - APM2020-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802020000200152Sao Paulo Medical Journal v.138 n.2 2020reponame:São Paulo medical journal (Online)instname:Associação Paulista de Medicinainstacron:APM10.1590/1516-3180.2019.0436.r1.19122019info:eu-repo/semantics/openAccessRomagna,Elisa SfoggiaAppel-da-Silva,Marcelo CamposSuwa,EijiMaeda,Fabio KunihiroMattos,Angelo Alves deTovo,Cristiane Valleeng2020-05-28T00:00:00Zoai:scielo:S1516-31802020000200152Revistahttp://www.scielo.br/spmjhttps://old.scielo.br/oai/scielo-oai.phprevistas@apm.org.br1806-94601516-3180opendoar:2020-05-28T00:00São Paulo medical journal (Online) - Associação Paulista de Medicinafalse |
dc.title.none.fl_str_mv |
Muscle depletion in cirrhotic patients assessed using computed tomography: a cross-sectional study |
title |
Muscle depletion in cirrhotic patients assessed using computed tomography: a cross-sectional study |
spellingShingle |
Muscle depletion in cirrhotic patients assessed using computed tomography: a cross-sectional study Romagna,Elisa Sfoggia Liver cirrhosis Sarcopenia Mortality Malnutrition Muscle depletion Cirrhosis Chronic liver disease |
title_short |
Muscle depletion in cirrhotic patients assessed using computed tomography: a cross-sectional study |
title_full |
Muscle depletion in cirrhotic patients assessed using computed tomography: a cross-sectional study |
title_fullStr |
Muscle depletion in cirrhotic patients assessed using computed tomography: a cross-sectional study |
title_full_unstemmed |
Muscle depletion in cirrhotic patients assessed using computed tomography: a cross-sectional study |
title_sort |
Muscle depletion in cirrhotic patients assessed using computed tomography: a cross-sectional study |
author |
Romagna,Elisa Sfoggia |
author_facet |
Romagna,Elisa Sfoggia Appel-da-Silva,Marcelo Campos Suwa,Eiji Maeda,Fabio Kunihiro Mattos,Angelo Alves de Tovo,Cristiane Valle |
author_role |
author |
author2 |
Appel-da-Silva,Marcelo Campos Suwa,Eiji Maeda,Fabio Kunihiro Mattos,Angelo Alves de Tovo,Cristiane Valle |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Romagna,Elisa Sfoggia Appel-da-Silva,Marcelo Campos Suwa,Eiji Maeda,Fabio Kunihiro Mattos,Angelo Alves de Tovo,Cristiane Valle |
dc.subject.por.fl_str_mv |
Liver cirrhosis Sarcopenia Mortality Malnutrition Muscle depletion Cirrhosis Chronic liver disease |
topic |
Liver cirrhosis Sarcopenia Mortality Malnutrition Muscle depletion Cirrhosis Chronic liver disease |
description |
ABSTRACT BACKGROUND: Sarcopenia is a common complication in patients with cirrhosis and may lead to increased morbidity and mortality. OBJECTIVE: To investigate the prevalence of sarcopenia and its association with disease severity scores, among patients with cirrhosis. DESIGN AND SETTING: Observational and retrospective cohort study carried out in a tertiary-care hospital in southern Brazil. METHODS: This study was conducted among patients with chronic liver disease who were followed up at the gastroenterology and hepatology outpatient clinic of a tertiary-care hospital in southern Brazil and who underwent computed tomography scans of the abdomen through any indication. RESULTS: We included 83 patients in the study. In the population evaluated, there was a predominance of males (57.80%) and the mean age was 56 years. Hepatitis B or C virus was present in the genesis of the disease in 34.9% of the cases, followed by an etiology of alcohol abuse (30.1%). Sarcopenia was diagnosed in 41 (49.4%) of the patients when the cutoff point for cirrhotic patients was used. There was no significant correlation between the Child-Pugh and MELD severity scores and the occurrence of sarcopenia. CONCLUSION: Sarcopenia presents high prevalence among patients with chronic liver disease, without any association with predictors of severity. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-03-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802020000200152 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802020000200152 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/1516-3180.2019.0436.r1.19122019 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Associação Paulista de Medicina - APM |
publisher.none.fl_str_mv |
Associação Paulista de Medicina - APM |
dc.source.none.fl_str_mv |
Sao Paulo Medical Journal v.138 n.2 2020 reponame:São Paulo medical journal (Online) instname:Associação Paulista de Medicina instacron:APM |
instname_str |
Associação Paulista de Medicina |
instacron_str |
APM |
institution |
APM |
reponame_str |
São Paulo medical journal (Online) |
collection |
São Paulo medical journal (Online) |
repository.name.fl_str_mv |
São Paulo medical journal (Online) - Associação Paulista de Medicina |
repository.mail.fl_str_mv |
revistas@apm.org.br |
_version_ |
1754209267192168448 |