Muscle depletion in cirrhotic patients assessed using computed tomography: a cross-sectional study

Detalhes bibliográficos
Autor(a) principal: Romagna,Elisa Sfoggia
Data de Publicação: 2020
Outros Autores: Appel-da-Silva,Marcelo Campos, Suwa,Eiji, Maeda,Fabio Kunihiro, Mattos,Angelo Alves de, Tovo,Cristiane Valle
Tipo de documento: Artigo
Idioma: eng
Título da fonte: São Paulo medical journal (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802020000200152
Resumo: ABSTRACT BACKGROUND: Sarcopenia is a common complication in patients with cirrhosis and may lead to increased morbidity and mortality. OBJECTIVE: To investigate the prevalence of sarcopenia and its association with disease severity scores, among patients with cirrhosis. DESIGN AND SETTING: Observational and retrospective cohort study carried out in a tertiary-care hospital in southern Brazil. METHODS: This study was conducted among patients with chronic liver disease who were followed up at the gastroenterology and hepatology outpatient clinic of a tertiary-care hospital in southern Brazil and who underwent computed tomography scans of the abdomen through any indication. RESULTS: We included 83 patients in the study. In the population evaluated, there was a predominance of males (57.80%) and the mean age was 56 years. Hepatitis B or C virus was present in the genesis of the disease in 34.9% of the cases, followed by an etiology of alcohol abuse (30.1%). Sarcopenia was diagnosed in 41 (49.4%) of the patients when the cutoff point for cirrhotic patients was used. There was no significant correlation between the Child-Pugh and MELD severity scores and the occurrence of sarcopenia. CONCLUSION: Sarcopenia presents high prevalence among patients with chronic liver disease, without any association with predictors of severity.
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spelling Muscle depletion in cirrhotic patients assessed using computed tomography: a cross-sectional studyLiver cirrhosisSarcopeniaMortalityMalnutritionMuscle depletionCirrhosisChronic liver diseaseABSTRACT BACKGROUND: Sarcopenia is a common complication in patients with cirrhosis and may lead to increased morbidity and mortality. OBJECTIVE: To investigate the prevalence of sarcopenia and its association with disease severity scores, among patients with cirrhosis. DESIGN AND SETTING: Observational and retrospective cohort study carried out in a tertiary-care hospital in southern Brazil. METHODS: This study was conducted among patients with chronic liver disease who were followed up at the gastroenterology and hepatology outpatient clinic of a tertiary-care hospital in southern Brazil and who underwent computed tomography scans of the abdomen through any indication. RESULTS: We included 83 patients in the study. In the population evaluated, there was a predominance of males (57.80%) and the mean age was 56 years. Hepatitis B or C virus was present in the genesis of the disease in 34.9% of the cases, followed by an etiology of alcohol abuse (30.1%). Sarcopenia was diagnosed in 41 (49.4%) of the patients when the cutoff point for cirrhotic patients was used. There was no significant correlation between the Child-Pugh and MELD severity scores and the occurrence of sarcopenia. CONCLUSION: Sarcopenia presents high prevalence among patients with chronic liver disease, without any association with predictors of severity.Associação Paulista de Medicina - APM2020-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802020000200152Sao Paulo Medical Journal v.138 n.2 2020reponame:São Paulo medical journal (Online)instname:Associação Paulista de Medicinainstacron:APM10.1590/1516-3180.2019.0436.r1.19122019info:eu-repo/semantics/openAccessRomagna,Elisa SfoggiaAppel-da-Silva,Marcelo CamposSuwa,EijiMaeda,Fabio KunihiroMattos,Angelo Alves deTovo,Cristiane Valleeng2020-05-28T00:00:00Zoai:scielo:S1516-31802020000200152Revistahttp://www.scielo.br/spmjhttps://old.scielo.br/oai/scielo-oai.phprevistas@apm.org.br1806-94601516-3180opendoar:2020-05-28T00:00São Paulo medical journal (Online) - Associação Paulista de Medicinafalse
dc.title.none.fl_str_mv Muscle depletion in cirrhotic patients assessed using computed tomography: a cross-sectional study
title Muscle depletion in cirrhotic patients assessed using computed tomography: a cross-sectional study
spellingShingle Muscle depletion in cirrhotic patients assessed using computed tomography: a cross-sectional study
Romagna,Elisa Sfoggia
Liver cirrhosis
Sarcopenia
Mortality
Malnutrition
Muscle depletion
Cirrhosis
Chronic liver disease
title_short Muscle depletion in cirrhotic patients assessed using computed tomography: a cross-sectional study
title_full Muscle depletion in cirrhotic patients assessed using computed tomography: a cross-sectional study
title_fullStr Muscle depletion in cirrhotic patients assessed using computed tomography: a cross-sectional study
title_full_unstemmed Muscle depletion in cirrhotic patients assessed using computed tomography: a cross-sectional study
title_sort Muscle depletion in cirrhotic patients assessed using computed tomography: a cross-sectional study
author Romagna,Elisa Sfoggia
author_facet Romagna,Elisa Sfoggia
Appel-da-Silva,Marcelo Campos
Suwa,Eiji
Maeda,Fabio Kunihiro
Mattos,Angelo Alves de
Tovo,Cristiane Valle
author_role author
author2 Appel-da-Silva,Marcelo Campos
Suwa,Eiji
Maeda,Fabio Kunihiro
Mattos,Angelo Alves de
Tovo,Cristiane Valle
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Romagna,Elisa Sfoggia
Appel-da-Silva,Marcelo Campos
Suwa,Eiji
Maeda,Fabio Kunihiro
Mattos,Angelo Alves de
Tovo,Cristiane Valle
dc.subject.por.fl_str_mv Liver cirrhosis
Sarcopenia
Mortality
Malnutrition
Muscle depletion
Cirrhosis
Chronic liver disease
topic Liver cirrhosis
Sarcopenia
Mortality
Malnutrition
Muscle depletion
Cirrhosis
Chronic liver disease
description ABSTRACT BACKGROUND: Sarcopenia is a common complication in patients with cirrhosis and may lead to increased morbidity and mortality. OBJECTIVE: To investigate the prevalence of sarcopenia and its association with disease severity scores, among patients with cirrhosis. DESIGN AND SETTING: Observational and retrospective cohort study carried out in a tertiary-care hospital in southern Brazil. METHODS: This study was conducted among patients with chronic liver disease who were followed up at the gastroenterology and hepatology outpatient clinic of a tertiary-care hospital in southern Brazil and who underwent computed tomography scans of the abdomen through any indication. RESULTS: We included 83 patients in the study. In the population evaluated, there was a predominance of males (57.80%) and the mean age was 56 years. Hepatitis B or C virus was present in the genesis of the disease in 34.9% of the cases, followed by an etiology of alcohol abuse (30.1%). Sarcopenia was diagnosed in 41 (49.4%) of the patients when the cutoff point for cirrhotic patients was used. There was no significant correlation between the Child-Pugh and MELD severity scores and the occurrence of sarcopenia. CONCLUSION: Sarcopenia presents high prevalence among patients with chronic liver disease, without any association with predictors of severity.
publishDate 2020
dc.date.none.fl_str_mv 2020-03-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802020000200152
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dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/1516-3180.2019.0436.r1.19122019
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Associação Paulista de Medicina - APM
publisher.none.fl_str_mv Associação Paulista de Medicina - APM
dc.source.none.fl_str_mv Sao Paulo Medical Journal v.138 n.2 2020
reponame:São Paulo medical journal (Online)
instname:Associação Paulista de Medicina
instacron:APM
instname_str Associação Paulista de Medicina
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institution APM
reponame_str São Paulo medical journal (Online)
collection São Paulo medical journal (Online)
repository.name.fl_str_mv São Paulo medical journal (Online) - Associação Paulista de Medicina
repository.mail.fl_str_mv revistas@apm.org.br
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