Does the use of paclitaxel or rapamycin-eluting stent decrease further need for coronary-artery bypass grafting when compared with bare-metal stent?

Detalhes bibliográficos
Autor(a) principal: Lemos Júnior, Hernani Pinto de
Data de Publicação: 2007
Outros Autores: Atallah, Álvaro Nagib
Tipo de documento: Artigo
Idioma: eng
Título da fonte: São Paulo medical journal (Online)
Texto Completo: https://periodicosapm.emnuvens.com.br/spmj/article/view/2125
Resumo: CONTEXT AND OBJECTIVE: The safety and effi cacy of drug-eluting stents reduce the need for surgical revascularization. The objective of the present study was to investigate whether paclitaxel or rapamycin-eluting stent are effective in avoiding the need for coronary-artery bypass grafting. METHODS: This was a systematic review of the literature using the methodology of the Cochrane Collaboration. The type of study considered was controlled randomized trials; the type of intervention was drug-eluting or bare-metal stents; and the main outcome investigated was coronary-artery bypass grafting. RESULTS: The ten studies included in this systematic review did not show any statistically signifi cant difference between the drug-eluting stents and the bare-metal stents with regard to the outcome of coronary-artery bypass grafting (confi dence interval: 0.31 to 1.42). CONCLUSION: The surgical revascularization rate was not reduced by the use of drug-eluting stents.
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spelling Does the use of paclitaxel or rapamycin-eluting stent decrease further need for coronary-artery bypass grafting when compared with bare-metal stent?O uso de stents recobertos com paclitaxel ou rapamicina diminui o número de cirurgias de revascularização cardíaca quando comparado aos stents convencionais? Angina pectorisPonte de artéria coronáriaAngioplastia transluminal percutânea coronáriaRevascularização miocárdicaCirurgia cardíacaAngina pectorisCoronary artery bypassPercutaneous transluminal coronary angioplastyMyocardial revascularizationThoracic surgeryCONTEXT AND OBJECTIVE: The safety and effi cacy of drug-eluting stents reduce the need for surgical revascularization. The objective of the present study was to investigate whether paclitaxel or rapamycin-eluting stent are effective in avoiding the need for coronary-artery bypass grafting. METHODS: This was a systematic review of the literature using the methodology of the Cochrane Collaboration. The type of study considered was controlled randomized trials; the type of intervention was drug-eluting or bare-metal stents; and the main outcome investigated was coronary-artery bypass grafting. RESULTS: The ten studies included in this systematic review did not show any statistically signifi cant difference between the drug-eluting stents and the bare-metal stents with regard to the outcome of coronary-artery bypass grafting (confi dence interval: 0.31 to 1.42). CONCLUSION: The surgical revascularization rate was not reduced by the use of drug-eluting stents.CONTEXTO E OBJETIVO: A segurança e efi cácia dos stents recobertos com drogas reduz a necessidade da cirurgia de revascularização cardíaca. O objetivo foi verifi car se os stents recobertos com paclitaxel ou rapamicina são efetivos para evitar a necessidade de revascularização cirúrgica das coronárias. MÉTODOS: Revisão sistemática da literatura usando a metodologia do Centro Cochrane. Tipos de estudos: estudos clínicos randomizados; tipo de intervenção: stents recobertos com drogas ou stents convencionais; desfecho principal: cirurgia de revascularização cardíaca. RESULTADOS: Os 10 estudos incluídos nesta revisão sistemática não mostram diferença estatisticamente signifi cante entre os stents recobertos com drogas e os stents convencionais no desfecho principal, com intervalo de confi ança de 0.31, 1.42. CONCLUSÃO: A taxa de revascularização cardíaca não é reduzida pelo uso de stents recobertos com drogas.São Paulo Medical JournalSão Paulo Medical Journal2007-07-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://periodicosapm.emnuvens.com.br/spmj/article/view/2125São Paulo Medical Journal; Vol. 125 No. 4 (2007); 242-245São Paulo Medical Journal; v. 125 n. 4 (2007); 242-2451806-9460reponame:São Paulo medical journal (Online)instname:Associação Paulista de Medicinainstacron:APMenghttps://periodicosapm.emnuvens.com.br/spmj/article/view/2125/2023https://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessLemos Júnior, Hernani Pinto deAtallah, Álvaro Nagib2023-09-29T11:47:19Zoai:ojs.diagnosticoetratamento.emnuvens.com.br:article/2125Revistahttp://www.scielo.br/spmjPUBhttps://old.scielo.br/oai/scielo-oai.phprevistas@apm.org.br1806-94601516-3180opendoar:2023-09-29T11:47:19São Paulo medical journal (Online) - Associação Paulista de Medicinafalse
dc.title.none.fl_str_mv Does the use of paclitaxel or rapamycin-eluting stent decrease further need for coronary-artery bypass grafting when compared with bare-metal stent?
O uso de stents recobertos com paclitaxel ou rapamicina diminui o número de cirurgias de revascularização cardíaca quando comparado aos stents convencionais?
title Does the use of paclitaxel or rapamycin-eluting stent decrease further need for coronary-artery bypass grafting when compared with bare-metal stent?
spellingShingle Does the use of paclitaxel or rapamycin-eluting stent decrease further need for coronary-artery bypass grafting when compared with bare-metal stent?
Lemos Júnior, Hernani Pinto de
Angina pectoris
Ponte de artéria coronária
Angioplastia transluminal percutânea coronária
Revascularização miocárdica
Cirurgia cardíaca
Angina pectoris
Coronary artery bypass
Percutaneous transluminal coronary angioplasty
Myocardial revascularization
Thoracic surgery
title_short Does the use of paclitaxel or rapamycin-eluting stent decrease further need for coronary-artery bypass grafting when compared with bare-metal stent?
title_full Does the use of paclitaxel or rapamycin-eluting stent decrease further need for coronary-artery bypass grafting when compared with bare-metal stent?
title_fullStr Does the use of paclitaxel or rapamycin-eluting stent decrease further need for coronary-artery bypass grafting when compared with bare-metal stent?
title_full_unstemmed Does the use of paclitaxel or rapamycin-eluting stent decrease further need for coronary-artery bypass grafting when compared with bare-metal stent?
title_sort Does the use of paclitaxel or rapamycin-eluting stent decrease further need for coronary-artery bypass grafting when compared with bare-metal stent?
author Lemos Júnior, Hernani Pinto de
author_facet Lemos Júnior, Hernani Pinto de
Atallah, Álvaro Nagib
author_role author
author2 Atallah, Álvaro Nagib
author2_role author
dc.contributor.author.fl_str_mv Lemos Júnior, Hernani Pinto de
Atallah, Álvaro Nagib
dc.subject.por.fl_str_mv Angina pectoris
Ponte de artéria coronária
Angioplastia transluminal percutânea coronária
Revascularização miocárdica
Cirurgia cardíaca
Angina pectoris
Coronary artery bypass
Percutaneous transluminal coronary angioplasty
Myocardial revascularization
Thoracic surgery
topic Angina pectoris
Ponte de artéria coronária
Angioplastia transluminal percutânea coronária
Revascularização miocárdica
Cirurgia cardíaca
Angina pectoris
Coronary artery bypass
Percutaneous transluminal coronary angioplasty
Myocardial revascularization
Thoracic surgery
description CONTEXT AND OBJECTIVE: The safety and effi cacy of drug-eluting stents reduce the need for surgical revascularization. The objective of the present study was to investigate whether paclitaxel or rapamycin-eluting stent are effective in avoiding the need for coronary-artery bypass grafting. METHODS: This was a systematic review of the literature using the methodology of the Cochrane Collaboration. The type of study considered was controlled randomized trials; the type of intervention was drug-eluting or bare-metal stents; and the main outcome investigated was coronary-artery bypass grafting. RESULTS: The ten studies included in this systematic review did not show any statistically signifi cant difference between the drug-eluting stents and the bare-metal stents with regard to the outcome of coronary-artery bypass grafting (confi dence interval: 0.31 to 1.42). CONCLUSION: The surgical revascularization rate was not reduced by the use of drug-eluting stents.
publishDate 2007
dc.date.none.fl_str_mv 2007-07-07
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://periodicosapm.emnuvens.com.br/spmj/article/view/2125
url https://periodicosapm.emnuvens.com.br/spmj/article/view/2125
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://periodicosapm.emnuvens.com.br/spmj/article/view/2125/2023
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv São Paulo Medical Journal
São Paulo Medical Journal
publisher.none.fl_str_mv São Paulo Medical Journal
São Paulo Medical Journal
dc.source.none.fl_str_mv São Paulo Medical Journal; Vol. 125 No. 4 (2007); 242-245
São Paulo Medical Journal; v. 125 n. 4 (2007); 242-245
1806-9460
reponame:São Paulo medical journal (Online)
instname:Associação Paulista de Medicina
instacron:APM
instname_str Associação Paulista de Medicina
instacron_str APM
institution APM
reponame_str São Paulo medical journal (Online)
collection São Paulo medical journal (Online)
repository.name.fl_str_mv São Paulo medical journal (Online) - Associação Paulista de Medicina
repository.mail.fl_str_mv revistas@apm.org.br
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