Value of computed tomography for evaluating the subglottis in laryngeal and hypopharyngeal squamous cell carcinoma
Autor(a) principal: | |
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Data de Publicação: | 2007 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | São Paulo medical journal (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802007000200002 |
Resumo: | CONTEXT AND OBJECTIVE: Subglottic involvement in squamous cell carcinoma is a determining factor for contraindicating conservative partial surgery. The subglottis is easily identified by axial computed tomography sections. The present study aimed to evaluate the occurrence of false-negative and false-positive results, and the overall accuracy of staging by computed tomography, in order to detect the involvement of the subglottic laryngeal compartment, in cases of laryngeal and hypopharyngeal squamous cell carcinoma. DESIGN AND SETTING: Retrospective, non-randomized study of patients treated at Hospital Heliópolis, São Paulo, Brazil. METHODS: Computed tomography scans were performed on third-generation equipment with 5-mm slice thickness. Afterwards, all patients underwent surgical and anatomopathological examinations as the gold standard procedures. RESULTS: Among 60 patients, 14 were diagnosed with subglottic extension by surgical and histopathological examination. There were three false-negative and no false-positive results from computed tomography scans. The sensitivity and negative predictive value were 100.0%. Accuracy was 95.0%, specificity was 93.5% and positive predictive value was 82.4%. CONCLUSIONS: Computed tomography could serve as a powerful auxiliary method for staging laryngeal and hypopharyngeal cancer. However, precautions should be taken in analyzing computed tomography scan data, because vegetating lesions may also be projected into the subglottic compartment, without real involvement of the subglottis, which may cause a false-positive result. |
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Value of computed tomography for evaluating the subglottis in laryngeal and hypopharyngeal squamous cell carcinomaCancerNeckRadiologyLarynxHypopharynxCONTEXT AND OBJECTIVE: Subglottic involvement in squamous cell carcinoma is a determining factor for contraindicating conservative partial surgery. The subglottis is easily identified by axial computed tomography sections. The present study aimed to evaluate the occurrence of false-negative and false-positive results, and the overall accuracy of staging by computed tomography, in order to detect the involvement of the subglottic laryngeal compartment, in cases of laryngeal and hypopharyngeal squamous cell carcinoma. DESIGN AND SETTING: Retrospective, non-randomized study of patients treated at Hospital Heliópolis, São Paulo, Brazil. METHODS: Computed tomography scans were performed on third-generation equipment with 5-mm slice thickness. Afterwards, all patients underwent surgical and anatomopathological examinations as the gold standard procedures. RESULTS: Among 60 patients, 14 were diagnosed with subglottic extension by surgical and histopathological examination. There were three false-negative and no false-positive results from computed tomography scans. The sensitivity and negative predictive value were 100.0%. Accuracy was 95.0%, specificity was 93.5% and positive predictive value was 82.4%. CONCLUSIONS: Computed tomography could serve as a powerful auxiliary method for staging laryngeal and hypopharyngeal cancer. However, precautions should be taken in analyzing computed tomography scan data, because vegetating lesions may also be projected into the subglottic compartment, without real involvement of the subglottis, which may cause a false-positive result.Associação Paulista de Medicina - APM2007-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802007000200002Sao Paulo Medical Journal v.125 n.2 2007reponame:São Paulo medical journal (Online)instname:Associação Paulista de Medicinainstacron:APM10.1590/S1516-31802007000200002info:eu-repo/semantics/openAccessSouza,Ricardo Pires deBarros,Nestor dePaes Junior,Ademar José de OliveiraTornin,Olger de SouzaRapoport,AbrãoCerri,Giovanni Guidoeng2007-07-03T00:00:00Zoai:scielo:S1516-31802007000200002Revistahttp://www.scielo.br/spmjhttps://old.scielo.br/oai/scielo-oai.phprevistas@apm.org.br1806-94601516-3180opendoar:2007-07-03T00:00São Paulo medical journal (Online) - Associação Paulista de Medicinafalse |
dc.title.none.fl_str_mv |
Value of computed tomography for evaluating the subglottis in laryngeal and hypopharyngeal squamous cell carcinoma |
title |
Value of computed tomography for evaluating the subglottis in laryngeal and hypopharyngeal squamous cell carcinoma |
spellingShingle |
Value of computed tomography for evaluating the subglottis in laryngeal and hypopharyngeal squamous cell carcinoma Souza,Ricardo Pires de Cancer Neck Radiology Larynx Hypopharynx |
title_short |
Value of computed tomography for evaluating the subglottis in laryngeal and hypopharyngeal squamous cell carcinoma |
title_full |
Value of computed tomography for evaluating the subglottis in laryngeal and hypopharyngeal squamous cell carcinoma |
title_fullStr |
Value of computed tomography for evaluating the subglottis in laryngeal and hypopharyngeal squamous cell carcinoma |
title_full_unstemmed |
Value of computed tomography for evaluating the subglottis in laryngeal and hypopharyngeal squamous cell carcinoma |
title_sort |
Value of computed tomography for evaluating the subglottis in laryngeal and hypopharyngeal squamous cell carcinoma |
author |
Souza,Ricardo Pires de |
author_facet |
Souza,Ricardo Pires de Barros,Nestor de Paes Junior,Ademar José de Oliveira Tornin,Olger de Souza Rapoport,Abrão Cerri,Giovanni Guido |
author_role |
author |
author2 |
Barros,Nestor de Paes Junior,Ademar José de Oliveira Tornin,Olger de Souza Rapoport,Abrão Cerri,Giovanni Guido |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Souza,Ricardo Pires de Barros,Nestor de Paes Junior,Ademar José de Oliveira Tornin,Olger de Souza Rapoport,Abrão Cerri,Giovanni Guido |
dc.subject.por.fl_str_mv |
Cancer Neck Radiology Larynx Hypopharynx |
topic |
Cancer Neck Radiology Larynx Hypopharynx |
description |
CONTEXT AND OBJECTIVE: Subglottic involvement in squamous cell carcinoma is a determining factor for contraindicating conservative partial surgery. The subglottis is easily identified by axial computed tomography sections. The present study aimed to evaluate the occurrence of false-negative and false-positive results, and the overall accuracy of staging by computed tomography, in order to detect the involvement of the subglottic laryngeal compartment, in cases of laryngeal and hypopharyngeal squamous cell carcinoma. DESIGN AND SETTING: Retrospective, non-randomized study of patients treated at Hospital Heliópolis, São Paulo, Brazil. METHODS: Computed tomography scans were performed on third-generation equipment with 5-mm slice thickness. Afterwards, all patients underwent surgical and anatomopathological examinations as the gold standard procedures. RESULTS: Among 60 patients, 14 were diagnosed with subglottic extension by surgical and histopathological examination. There were three false-negative and no false-positive results from computed tomography scans. The sensitivity and negative predictive value were 100.0%. Accuracy was 95.0%, specificity was 93.5% and positive predictive value was 82.4%. CONCLUSIONS: Computed tomography could serve as a powerful auxiliary method for staging laryngeal and hypopharyngeal cancer. However, precautions should be taken in analyzing computed tomography scan data, because vegetating lesions may also be projected into the subglottic compartment, without real involvement of the subglottis, which may cause a false-positive result. |
publishDate |
2007 |
dc.date.none.fl_str_mv |
2007-03-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802007000200002 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802007000200002 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S1516-31802007000200002 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Associação Paulista de Medicina - APM |
publisher.none.fl_str_mv |
Associação Paulista de Medicina - APM |
dc.source.none.fl_str_mv |
Sao Paulo Medical Journal v.125 n.2 2007 reponame:São Paulo medical journal (Online) instname:Associação Paulista de Medicina instacron:APM |
instname_str |
Associação Paulista de Medicina |
instacron_str |
APM |
institution |
APM |
reponame_str |
São Paulo medical journal (Online) |
collection |
São Paulo medical journal (Online) |
repository.name.fl_str_mv |
São Paulo medical journal (Online) - Associação Paulista de Medicina |
repository.mail.fl_str_mv |
revistas@apm.org.br |
_version_ |
1754209261735378944 |