Value of computed tomography for evaluating the subglottis in laryngeal and hypopharyngeal squamous cell carcinoma

Detalhes bibliográficos
Autor(a) principal: Souza,Ricardo Pires de
Data de Publicação: 2007
Outros Autores: Barros,Nestor de, Paes Junior,Ademar José de Oliveira, Tornin,Olger de Souza, Rapoport,Abrão, Cerri,Giovanni Guido
Tipo de documento: Artigo
Idioma: eng
Título da fonte: São Paulo medical journal (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802007000200002
Resumo: CONTEXT AND OBJECTIVE: Subglottic involvement in squamous cell carcinoma is a determining factor for contraindicating conservative partial surgery. The subglottis is easily identified by axial computed tomography sections. The present study aimed to evaluate the occurrence of false-negative and false-positive results, and the overall accuracy of staging by computed tomography, in order to detect the involvement of the subglottic laryngeal compartment, in cases of laryngeal and hypopharyngeal squamous cell carcinoma. DESIGN AND SETTING: Retrospective, non-randomized study of patients treated at Hospital Heliópolis, São Paulo, Brazil. METHODS: Computed tomography scans were performed on third-generation equipment with 5-mm slice thickness. Afterwards, all patients underwent surgical and anatomopathological examinations as the gold standard procedures. RESULTS: Among 60 patients, 14 were diagnosed with subglottic extension by surgical and histopathological examination. There were three false-negative and no false-positive results from computed tomography scans. The sensitivity and negative predictive value were 100.0%. Accuracy was 95.0%, specificity was 93.5% and positive predictive value was 82.4%. CONCLUSIONS: Computed tomography could serve as a powerful auxiliary method for staging laryngeal and hypopharyngeal cancer. However, precautions should be taken in analyzing computed tomography scan data, because vegetating lesions may also be projected into the subglottic compartment, without real involvement of the subglottis, which may cause a false-positive result.
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spelling Value of computed tomography for evaluating the subglottis in laryngeal and hypopharyngeal squamous cell carcinomaCancerNeckRadiologyLarynxHypopharynxCONTEXT AND OBJECTIVE: Subglottic involvement in squamous cell carcinoma is a determining factor for contraindicating conservative partial surgery. The subglottis is easily identified by axial computed tomography sections. The present study aimed to evaluate the occurrence of false-negative and false-positive results, and the overall accuracy of staging by computed tomography, in order to detect the involvement of the subglottic laryngeal compartment, in cases of laryngeal and hypopharyngeal squamous cell carcinoma. DESIGN AND SETTING: Retrospective, non-randomized study of patients treated at Hospital Heliópolis, São Paulo, Brazil. METHODS: Computed tomography scans were performed on third-generation equipment with 5-mm slice thickness. Afterwards, all patients underwent surgical and anatomopathological examinations as the gold standard procedures. RESULTS: Among 60 patients, 14 were diagnosed with subglottic extension by surgical and histopathological examination. There were three false-negative and no false-positive results from computed tomography scans. The sensitivity and negative predictive value were 100.0%. Accuracy was 95.0%, specificity was 93.5% and positive predictive value was 82.4%. CONCLUSIONS: Computed tomography could serve as a powerful auxiliary method for staging laryngeal and hypopharyngeal cancer. However, precautions should be taken in analyzing computed tomography scan data, because vegetating lesions may also be projected into the subglottic compartment, without real involvement of the subglottis, which may cause a false-positive result.Associação Paulista de Medicina - APM2007-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802007000200002Sao Paulo Medical Journal v.125 n.2 2007reponame:São Paulo medical journal (Online)instname:Associação Paulista de Medicinainstacron:APM10.1590/S1516-31802007000200002info:eu-repo/semantics/openAccessSouza,Ricardo Pires deBarros,Nestor dePaes Junior,Ademar José de OliveiraTornin,Olger de SouzaRapoport,AbrãoCerri,Giovanni Guidoeng2007-07-03T00:00:00Zoai:scielo:S1516-31802007000200002Revistahttp://www.scielo.br/spmjhttps://old.scielo.br/oai/scielo-oai.phprevistas@apm.org.br1806-94601516-3180opendoar:2007-07-03T00:00São Paulo medical journal (Online) - Associação Paulista de Medicinafalse
dc.title.none.fl_str_mv Value of computed tomography for evaluating the subglottis in laryngeal and hypopharyngeal squamous cell carcinoma
title Value of computed tomography for evaluating the subglottis in laryngeal and hypopharyngeal squamous cell carcinoma
spellingShingle Value of computed tomography for evaluating the subglottis in laryngeal and hypopharyngeal squamous cell carcinoma
Souza,Ricardo Pires de
Cancer
Neck
Radiology
Larynx
Hypopharynx
title_short Value of computed tomography for evaluating the subglottis in laryngeal and hypopharyngeal squamous cell carcinoma
title_full Value of computed tomography for evaluating the subglottis in laryngeal and hypopharyngeal squamous cell carcinoma
title_fullStr Value of computed tomography for evaluating the subglottis in laryngeal and hypopharyngeal squamous cell carcinoma
title_full_unstemmed Value of computed tomography for evaluating the subglottis in laryngeal and hypopharyngeal squamous cell carcinoma
title_sort Value of computed tomography for evaluating the subglottis in laryngeal and hypopharyngeal squamous cell carcinoma
author Souza,Ricardo Pires de
author_facet Souza,Ricardo Pires de
Barros,Nestor de
Paes Junior,Ademar José de Oliveira
Tornin,Olger de Souza
Rapoport,Abrão
Cerri,Giovanni Guido
author_role author
author2 Barros,Nestor de
Paes Junior,Ademar José de Oliveira
Tornin,Olger de Souza
Rapoport,Abrão
Cerri,Giovanni Guido
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Souza,Ricardo Pires de
Barros,Nestor de
Paes Junior,Ademar José de Oliveira
Tornin,Olger de Souza
Rapoport,Abrão
Cerri,Giovanni Guido
dc.subject.por.fl_str_mv Cancer
Neck
Radiology
Larynx
Hypopharynx
topic Cancer
Neck
Radiology
Larynx
Hypopharynx
description CONTEXT AND OBJECTIVE: Subglottic involvement in squamous cell carcinoma is a determining factor for contraindicating conservative partial surgery. The subglottis is easily identified by axial computed tomography sections. The present study aimed to evaluate the occurrence of false-negative and false-positive results, and the overall accuracy of staging by computed tomography, in order to detect the involvement of the subglottic laryngeal compartment, in cases of laryngeal and hypopharyngeal squamous cell carcinoma. DESIGN AND SETTING: Retrospective, non-randomized study of patients treated at Hospital Heliópolis, São Paulo, Brazil. METHODS: Computed tomography scans were performed on third-generation equipment with 5-mm slice thickness. Afterwards, all patients underwent surgical and anatomopathological examinations as the gold standard procedures. RESULTS: Among 60 patients, 14 were diagnosed with subglottic extension by surgical and histopathological examination. There were three false-negative and no false-positive results from computed tomography scans. The sensitivity and negative predictive value were 100.0%. Accuracy was 95.0%, specificity was 93.5% and positive predictive value was 82.4%. CONCLUSIONS: Computed tomography could serve as a powerful auxiliary method for staging laryngeal and hypopharyngeal cancer. However, precautions should be taken in analyzing computed tomography scan data, because vegetating lesions may also be projected into the subglottic compartment, without real involvement of the subglottis, which may cause a false-positive result.
publishDate 2007
dc.date.none.fl_str_mv 2007-03-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802007000200002
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802007000200002
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1516-31802007000200002
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Associação Paulista de Medicina - APM
publisher.none.fl_str_mv Associação Paulista de Medicina - APM
dc.source.none.fl_str_mv Sao Paulo Medical Journal v.125 n.2 2007
reponame:São Paulo medical journal (Online)
instname:Associação Paulista de Medicina
instacron:APM
instname_str Associação Paulista de Medicina
instacron_str APM
institution APM
reponame_str São Paulo medical journal (Online)
collection São Paulo medical journal (Online)
repository.name.fl_str_mv São Paulo medical journal (Online) - Associação Paulista de Medicina
repository.mail.fl_str_mv revistas@apm.org.br
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