Hepatitis C virus seroprevalence and risk factors among patients with HIV infection
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Publication Date: | 2001 |
Other Authors: | , |
Format: | Article |
Language: | eng |
Source: | Revista do Instituto de Medicina Tropical de São Paulo |
Download full: | https://www.revistas.usp.br/rimtsp/article/view/30475 |
Summary: | The objective of this study was to evaluate the prevalence and risk factors associated with HCV infection in a group of HIV seropositive patients. We analyzed the medical records of 1,457 patients. All patients were tested for HCV infection by third generation ELISA. Whenever possible, a sample of the positive patients was also tested for HCV by PCR. HCV positive patients were analyzed according to their risk factors for both infections. The prevalence of anti-HCV positive patients was 17.7% (258 patients). Eighty-two (82) of these patients were also tested by PCR and 81 were positive for HCV virus (98%). One hundred fifty-one (58.5%) were intravenous drug users (IDU); 42 (16.3%) were sexual partners of HIV patients; 23 (8.9%) were homosexual males; 12 (4.7%) had received blood transfusion; 61 (17.5%) had promiscuous sexual habits; 14 (5.4%) denied any risk factor; 12 (4.7%) were sexual partners of IDU. Two hundred four patients mentioned only one risk factor. Among them, 28 (10.9%) were sexual partners of HIV-positive patients. Although intravenous drug use was the most important risk factor for co-infection, sexual transmission seemed to contribute to the high HCV seroprevalence in this group of patients. |
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Hepatitis C virus seroprevalence and risk factors among patients with HIV infection Prevalência e fatores de risco da hepatite C em pacientes infectados pelo vírus da imunodeficiência humana HIV-HCVViral HepatitisEpidemiologySeroprevalenceBrazil The objective of this study was to evaluate the prevalence and risk factors associated with HCV infection in a group of HIV seropositive patients. We analyzed the medical records of 1,457 patients. All patients were tested for HCV infection by third generation ELISA. Whenever possible, a sample of the positive patients was also tested for HCV by PCR. HCV positive patients were analyzed according to their risk factors for both infections. The prevalence of anti-HCV positive patients was 17.7% (258 patients). Eighty-two (82) of these patients were also tested by PCR and 81 were positive for HCV virus (98%). One hundred fifty-one (58.5%) were intravenous drug users (IDU); 42 (16.3%) were sexual partners of HIV patients; 23 (8.9%) were homosexual males; 12 (4.7%) had received blood transfusion; 61 (17.5%) had promiscuous sexual habits; 14 (5.4%) denied any risk factor; 12 (4.7%) were sexual partners of IDU. Two hundred four patients mentioned only one risk factor. Among them, 28 (10.9%) were sexual partners of HIV-positive patients. Although intravenous drug use was the most important risk factor for co-infection, sexual transmission seemed to contribute to the high HCV seroprevalence in this group of patients. O objetivo do presente estudo foi avaliar a prevalência e os fatores de risco associados à infecção pelo vírus da hepatite C (VHC) em um grupo de pacientes soropositivos para o HIV. Analisamos os prontuários médicos de 1.457 pacientes. O diagnóstico laboratorial de infecção pelo VHC foi feito utilizando-se ELISA de terceira geração. Uma parte dos pacientes soropositivos para VHC foram também submetidos à realização de PCR. Os pacientes soropositivos para VHC foram analisados em relação aos fatores de risco para ambas as infecções. A prevalência de pacientes soropositivos para VHC foi de 17,7% (258 pacientes). 82 desses pacientes foram testados para VHC por PCR e 81 (98%) apresentaram-se com resultado positivo. 151 (58,5%) referiram uso de drogas endovenosas (UDE), 42 (16,3%) eram parceiros sexuais de pacientes infectados pelo HIV, 23 (8,9%) eram homossexuais masculinos, 12 (4,7%) tinham recebido transfusão sanguínea, 61 (17,5%) referiram promiscuidade sexual, 14 (5,4%) negaram qualquer fator de risco, 12 (4,7%) eram parceiros sexuais de UDE. 204 pacientes referiram apenas um fator de risco, 51 referiram dois diferentes fatores de risco e três referiram três diferentes fatores de risco. Entre os pacientes que referiram apenas um fator de risco, 28 em 204 (10,9%) eram parceiros sexuais de pacientes infectados pelo HIV. Embora o uso de drogas endovenosas tenha sido o fator de risco mais importante na determinação da co-infecção, a transmissão sexual parece ter contribuído para a alta soroprevalência do VHC nesse grupo de pacientes. Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo2001-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/rimtsp/article/view/30475Revista do Instituto de Medicina Tropical de São Paulo; Vol. 43 No. 1 (2001); 15-19 Revista do Instituto de Medicina Tropical de São Paulo; Vol. 43 Núm. 1 (2001); 15-19 Revista do Instituto de Medicina Tropical de São Paulo; v. 43 n. 1 (2001); 15-19 1678-99460036-4665reponame:Revista do Instituto de Medicina Tropical de São Pauloinstname:Instituto de Medicina Tropical (IMT)instacron:IMTenghttps://www.revistas.usp.br/rimtsp/article/view/30475/32359Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Pauloinfo:eu-repo/semantics/openAccessMENDES-CORRÊA, Maria Cássia J.BARONE, Antonio AlciGUASTINI, Cristina2012-07-07T13:30:29Zoai:revistas.usp.br:article/30475Revistahttp://www.revistas.usp.br/rimtsp/indexPUBhttps://www.revistas.usp.br/rimtsp/oai||revimtsp@usp.br1678-99460036-4665opendoar:2022-12-13T16:51:15.396108Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)true |
dc.title.none.fl_str_mv |
Hepatitis C virus seroprevalence and risk factors among patients with HIV infection Prevalência e fatores de risco da hepatite C em pacientes infectados pelo vírus da imunodeficiência humana |
title |
Hepatitis C virus seroprevalence and risk factors among patients with HIV infection |
spellingShingle |
Hepatitis C virus seroprevalence and risk factors among patients with HIV infection MENDES-CORRÊA, Maria Cássia J. HIV-HCV Viral Hepatitis Epidemiology Seroprevalence Brazil |
title_short |
Hepatitis C virus seroprevalence and risk factors among patients with HIV infection |
title_full |
Hepatitis C virus seroprevalence and risk factors among patients with HIV infection |
title_fullStr |
Hepatitis C virus seroprevalence and risk factors among patients with HIV infection |
title_full_unstemmed |
Hepatitis C virus seroprevalence and risk factors among patients with HIV infection |
title_sort |
Hepatitis C virus seroprevalence and risk factors among patients with HIV infection |
author |
MENDES-CORRÊA, Maria Cássia J. |
author_facet |
MENDES-CORRÊA, Maria Cássia J. BARONE, Antonio Alci GUASTINI, Cristina |
author_role |
author |
author2 |
BARONE, Antonio Alci GUASTINI, Cristina |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
MENDES-CORRÊA, Maria Cássia J. BARONE, Antonio Alci GUASTINI, Cristina |
dc.subject.por.fl_str_mv |
HIV-HCV Viral Hepatitis Epidemiology Seroprevalence Brazil |
topic |
HIV-HCV Viral Hepatitis Epidemiology Seroprevalence Brazil |
description |
The objective of this study was to evaluate the prevalence and risk factors associated with HCV infection in a group of HIV seropositive patients. We analyzed the medical records of 1,457 patients. All patients were tested for HCV infection by third generation ELISA. Whenever possible, a sample of the positive patients was also tested for HCV by PCR. HCV positive patients were analyzed according to their risk factors for both infections. The prevalence of anti-HCV positive patients was 17.7% (258 patients). Eighty-two (82) of these patients were also tested by PCR and 81 were positive for HCV virus (98%). One hundred fifty-one (58.5%) were intravenous drug users (IDU); 42 (16.3%) were sexual partners of HIV patients; 23 (8.9%) were homosexual males; 12 (4.7%) had received blood transfusion; 61 (17.5%) had promiscuous sexual habits; 14 (5.4%) denied any risk factor; 12 (4.7%) were sexual partners of IDU. Two hundred four patients mentioned only one risk factor. Among them, 28 (10.9%) were sexual partners of HIV-positive patients. Although intravenous drug use was the most important risk factor for co-infection, sexual transmission seemed to contribute to the high HCV seroprevalence in this group of patients. |
publishDate |
2001 |
dc.date.none.fl_str_mv |
2001-02-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/rimtsp/article/view/30475 |
url |
https://www.revistas.usp.br/rimtsp/article/view/30475 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/rimtsp/article/view/30475/32359 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo |
publisher.none.fl_str_mv |
Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo |
dc.source.none.fl_str_mv |
Revista do Instituto de Medicina Tropical de São Paulo; Vol. 43 No. 1 (2001); 15-19 Revista do Instituto de Medicina Tropical de São Paulo; Vol. 43 Núm. 1 (2001); 15-19 Revista do Instituto de Medicina Tropical de São Paulo; v. 43 n. 1 (2001); 15-19 1678-9946 0036-4665 reponame:Revista do Instituto de Medicina Tropical de São Paulo instname:Instituto de Medicina Tropical (IMT) instacron:IMT |
instname_str |
Instituto de Medicina Tropical (IMT) |
instacron_str |
IMT |
institution |
IMT |
reponame_str |
Revista do Instituto de Medicina Tropical de São Paulo |
collection |
Revista do Instituto de Medicina Tropical de São Paulo |
repository.name.fl_str_mv |
Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT) |
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