Nutrients, phytochemicals and bioactivity of wild Roman chamomile: a comparison between the herb and its preparations

Detalhes bibliográficos
Autor(a) principal: Guimarães, Rafaela
Data de Publicação: 2013
Outros Autores: Barros, Lillian, Dueñas, Montserrat, Calhelha, Ricardo C., Carvalho, Ana Maria, Santos-Buelga, Celestino, Queiroz, Maria João R.P., Ferreira, Isabel C.F.R.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10198/8531
Resumo: Roman chamomile, Chamaemelum nobile L. (Asteraceae), has been used for medicinal applications, mainly through oral dosage forms (decoctions and infusions). Herein, the nutritional characterization of C. nobile was performed, and herbal material and its decoction and infusion were submitted to an analysis of phytochemicals and bioactivity evaluation. The antioxidant activity was determined by free radicals scavenging activity, reducing power and inhibition of lipid peroxidation, the antitumour potential was tested in human tumour cell lines (breast, lung, colon, cervical and hepatocellular carcinomas), and the hepatotoxicity was evaluated using a porcine liver primary cell culture. C. nobile proved to be an equilibrated valuable herb rich in carbohydrates and proteins, and poor in fat, providing tocopherols, carotenoids and essential fatty acids (C18:2n6 and C18:3n3). Moreover, the herb and its infusion are a source of phenolic compounds (flavonoids such as flavonols and flavones, phenolic acids and derivatives) and organic acids (oxalic, quinic, malic, citric and fumaric acids) that showed antioxidant and antitumour activities, without hepatotoxicity. The most abundant compounds in the plant extract and infusion were 5-O-caffeoylquinic acid and an apigenin derivative. These, as also other bioactive compounds are affected in C. nobile decoction, leading to a lower antioxidant potential and absence of antitumour potential. The plant bioactivity could be explored in the medicine, food, and cosmetic industries.
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spelling Nutrients, phytochemicals and bioactivity of wild Roman chamomile: a comparison between the herb and its preparationsChamaemelum nobileRoman chamomileNutrientsPhenolic compoundsAntioxidant activityAntitumour potentialRoman chamomile, Chamaemelum nobile L. (Asteraceae), has been used for medicinal applications, mainly through oral dosage forms (decoctions and infusions). Herein, the nutritional characterization of C. nobile was performed, and herbal material and its decoction and infusion were submitted to an analysis of phytochemicals and bioactivity evaluation. The antioxidant activity was determined by free radicals scavenging activity, reducing power and inhibition of lipid peroxidation, the antitumour potential was tested in human tumour cell lines (breast, lung, colon, cervical and hepatocellular carcinomas), and the hepatotoxicity was evaluated using a porcine liver primary cell culture. C. nobile proved to be an equilibrated valuable herb rich in carbohydrates and proteins, and poor in fat, providing tocopherols, carotenoids and essential fatty acids (C18:2n6 and C18:3n3). Moreover, the herb and its infusion are a source of phenolic compounds (flavonoids such as flavonols and flavones, phenolic acids and derivatives) and organic acids (oxalic, quinic, malic, citric and fumaric acids) that showed antioxidant and antitumour activities, without hepatotoxicity. The most abundant compounds in the plant extract and infusion were 5-O-caffeoylquinic acid and an apigenin derivative. These, as also other bioactive compounds are affected in C. nobile decoction, leading to a lower antioxidant potential and absence of antitumour potential. The plant bioactivity could be explored in the medicine, food, and cosmetic industries.project PEst-OE/AGR/UI0690/2011 for financial support to CIMO. R. Guimarães, L. Barros and R. Calhelha thanks to FCT, POPH-QREN and FSE for their grants (SFRH/BD/78307/2011, SFRH/BPD/4609/2008 and SFRH/BPD/68344/2010). The GIP-USAL is financially supported by the Consolider-Ingenio 2010 Programme (FUN-C-FOOD, CSD2007-00063). M. Dueñas thanks the Spanish “Ramón y Cajal” Programme for a contract.ElsevierBiblioteca Digital do IPBGuimarães, RafaelaBarros, LillianDueñas, MontserratCalhelha, Ricardo C.Carvalho, Ana MariaSantos-Buelga, CelestinoQueiroz, Maria João R.P.Ferreira, Isabel C.F.R.2013-07-23T14:31:49Z20132013-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfapplication/pdfhttp://hdl.handle.net/10198/8531engGuimarães, Rafaela; Barros, Lillian; Dueñas, Montserrat; Calhelha, Ricardo C.; Carvalho, Ana Maria; Santos-Buelga, Celestino; Queiroz, Maria João R.P.Q.; Ferreira, Isabel C.F.R. (2013). Nutrients, phytochemicals and bioactivity of wild Roman chamomile: a comparison between the herb and its preparations. Food Chemistry. ISSN 0308-8146. 136:2, p. 718–7250308-814610.1016/j.foodchem.2012.08.025info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-21T10:20:52Zoai:bibliotecadigital.ipb.pt:10198/8531Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T23:00:01.480820Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Nutrients, phytochemicals and bioactivity of wild Roman chamomile: a comparison between the herb and its preparations
title Nutrients, phytochemicals and bioactivity of wild Roman chamomile: a comparison between the herb and its preparations
spellingShingle Nutrients, phytochemicals and bioactivity of wild Roman chamomile: a comparison between the herb and its preparations
Guimarães, Rafaela
Chamaemelum nobile
Roman chamomile
Nutrients
Phenolic compounds
Antioxidant activity
Antitumour potential
title_short Nutrients, phytochemicals and bioactivity of wild Roman chamomile: a comparison between the herb and its preparations
title_full Nutrients, phytochemicals and bioactivity of wild Roman chamomile: a comparison between the herb and its preparations
title_fullStr Nutrients, phytochemicals and bioactivity of wild Roman chamomile: a comparison between the herb and its preparations
title_full_unstemmed Nutrients, phytochemicals and bioactivity of wild Roman chamomile: a comparison between the herb and its preparations
title_sort Nutrients, phytochemicals and bioactivity of wild Roman chamomile: a comparison between the herb and its preparations
author Guimarães, Rafaela
author_facet Guimarães, Rafaela
Barros, Lillian
Dueñas, Montserrat
Calhelha, Ricardo C.
Carvalho, Ana Maria
Santos-Buelga, Celestino
Queiroz, Maria João R.P.
Ferreira, Isabel C.F.R.
author_role author
author2 Barros, Lillian
Dueñas, Montserrat
Calhelha, Ricardo C.
Carvalho, Ana Maria
Santos-Buelga, Celestino
Queiroz, Maria João R.P.
Ferreira, Isabel C.F.R.
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Biblioteca Digital do IPB
dc.contributor.author.fl_str_mv Guimarães, Rafaela
Barros, Lillian
Dueñas, Montserrat
Calhelha, Ricardo C.
Carvalho, Ana Maria
Santos-Buelga, Celestino
Queiroz, Maria João R.P.
Ferreira, Isabel C.F.R.
dc.subject.por.fl_str_mv Chamaemelum nobile
Roman chamomile
Nutrients
Phenolic compounds
Antioxidant activity
Antitumour potential
topic Chamaemelum nobile
Roman chamomile
Nutrients
Phenolic compounds
Antioxidant activity
Antitumour potential
description Roman chamomile, Chamaemelum nobile L. (Asteraceae), has been used for medicinal applications, mainly through oral dosage forms (decoctions and infusions). Herein, the nutritional characterization of C. nobile was performed, and herbal material and its decoction and infusion were submitted to an analysis of phytochemicals and bioactivity evaluation. The antioxidant activity was determined by free radicals scavenging activity, reducing power and inhibition of lipid peroxidation, the antitumour potential was tested in human tumour cell lines (breast, lung, colon, cervical and hepatocellular carcinomas), and the hepatotoxicity was evaluated using a porcine liver primary cell culture. C. nobile proved to be an equilibrated valuable herb rich in carbohydrates and proteins, and poor in fat, providing tocopherols, carotenoids and essential fatty acids (C18:2n6 and C18:3n3). Moreover, the herb and its infusion are a source of phenolic compounds (flavonoids such as flavonols and flavones, phenolic acids and derivatives) and organic acids (oxalic, quinic, malic, citric and fumaric acids) that showed antioxidant and antitumour activities, without hepatotoxicity. The most abundant compounds in the plant extract and infusion were 5-O-caffeoylquinic acid and an apigenin derivative. These, as also other bioactive compounds are affected in C. nobile decoction, leading to a lower antioxidant potential and absence of antitumour potential. The plant bioactivity could be explored in the medicine, food, and cosmetic industries.
publishDate 2013
dc.date.none.fl_str_mv 2013-07-23T14:31:49Z
2013
2013-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10198/8531
url http://hdl.handle.net/10198/8531
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Guimarães, Rafaela; Barros, Lillian; Dueñas, Montserrat; Calhelha, Ricardo C.; Carvalho, Ana Maria; Santos-Buelga, Celestino; Queiroz, Maria João R.P.Q.; Ferreira, Isabel C.F.R. (2013). Nutrients, phytochemicals and bioactivity of wild Roman chamomile: a comparison between the herb and its preparations. Food Chemistry. ISSN 0308-8146. 136:2, p. 718–725
0308-8146
10.1016/j.foodchem.2012.08.025
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
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dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
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collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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