Perfil Hematológico e Bioquímico Sérico de Ovinos Infectados com Nematóides e Medicados com Ivermectina e Closantel
Autor(a) principal: | |
---|---|
Data de Publicação: | 2011 |
Tipo de documento: | Dissertação |
Idioma: | por |
Título da fonte: | Biblioteca Digital de Teses e Dissertações da UFERSA |
Texto Completo: | https://repositorio.ufersa.edu.br/handle/tede/327 |
Resumo: | Despite its known resistance, the sheep are subject to endoparasitoses, which are the main limiting factor for its production worldwide, especially in tropical regions. This study aims to evaluate the changes in parasitic load, serum biochemical and hematological panel, and Famacha scores of mixed-bred sheep naturally infected with nematodes and treated with ivermectin and closantel. The study was conducted at July 2010, in a farm in the municipality of Mossoró, Rio Grande do Norte state, Brazil. We selected 41 animals were divided into three groups: group I- control (without treatment), group II- treated with ivermectin (0.2 mg/kg), and Group III- treated with closantel (5 mg/kg). Stool samples were collected on days 0, 7, 14 and 21 after treatment for quantitative analysis (EPG) and qualitative analysis (stool culture), we used samples from days 0, 14 and 21. The first blood sample was given on day 0, the second and third 24 and 72 hours after the first, respectively the fourth and fifth 7 and 14 days after the first of which analyzed the blood count, serum total protein, albumin and globulins, and albumin/globulins ratio. Famacha scores were determined the degree of each animal at all times of sampling. Closantel administration was effective for the reduction of parasite counts, especially Haemonchus contortus, in evaluated sheep. On the other hand, there was parasite resistance to ivermectin. Famacha data showed negative correlation with packed cell volume, leukocytes, hemoglobin, albumin, total protein, globulin and albumin/globulin ratio. The packed cell volume showed a strong and positive correlation with hemoglobin, albumin and total protein. Treatment with ivermectin and closantel were not responsible for considerable changes in hematological and biochemical parameters evaluated. |
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Ahid, Silvia Maria Mendeshttp://lattes.cnpq.br/5525213637103948Blanco, Benito Sotohttp://lattes.cnpq.br/5009042939501223Vieira, Luiz da Silvahttp://lattes.cnpq.br/5556932562390291http://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4594567E9Costa, Kizzy Millenn de Freitas Mendonça2016-08-15T20:31:01Z2014-11-112011-09-08COSTA, Kizzy Millenn de Freitas Mendonça. Hematologiy And Serum Biochemical Panel Sheep Infected with Nematodes and Dosed with Ivermectin and Closantel. 2011. 56 f. Dissertação (Mestrado em Sanidade e Produção Animal) - Universidade Federal Rural do Semi-Árido, Mossoró, 2011.https://repositorio.ufersa.edu.br/handle/tede/327Despite its known resistance, the sheep are subject to endoparasitoses, which are the main limiting factor for its production worldwide, especially in tropical regions. This study aims to evaluate the changes in parasitic load, serum biochemical and hematological panel, and Famacha scores of mixed-bred sheep naturally infected with nematodes and treated with ivermectin and closantel. The study was conducted at July 2010, in a farm in the municipality of Mossoró, Rio Grande do Norte state, Brazil. We selected 41 animals were divided into three groups: group I- control (without treatment), group II- treated with ivermectin (0.2 mg/kg), and Group III- treated with closantel (5 mg/kg). Stool samples were collected on days 0, 7, 14 and 21 after treatment for quantitative analysis (EPG) and qualitative analysis (stool culture), we used samples from days 0, 14 and 21. The first blood sample was given on day 0, the second and third 24 and 72 hours after the first, respectively the fourth and fifth 7 and 14 days after the first of which analyzed the blood count, serum total protein, albumin and globulins, and albumin/globulins ratio. Famacha scores were determined the degree of each animal at all times of sampling. Closantel administration was effective for the reduction of parasite counts, especially Haemonchus contortus, in evaluated sheep. On the other hand, there was parasite resistance to ivermectin. Famacha data showed negative correlation with packed cell volume, leukocytes, hemoglobin, albumin, total protein, globulin and albumin/globulin ratio. The packed cell volume showed a strong and positive correlation with hemoglobin, albumin and total protein. Treatment with ivermectin and closantel were not responsible for considerable changes in hematological and biochemical parameters evaluated.Apesar de sua conhecida resistência, os ovinos estão sujeitos as endoparasitoses, sendo este o principal fator limitante para a sua produção em todo o mundo, especialmente em regiões tropicais. Este trabalho objetiva avaliar a carga parasitária, o perfil hematológico e bioquímico sérico, e o grau Famacha de ovinos sem padrão racial definido infectados e tratados com ivermectina e closantel. O trabalho foi realizado no mês de julho de 2010, numa propriedade rural no município de Mossoró-RN. Foram selecionados 41 animais, os quais foram divididos em três grupos: grupo I- controle (sem tratamento), grupo II- tratado com ivermectina (0,2 mg/kg) e Grupo III- tratado com closantel (5 mg/kg). As amostras de fezes foram coletadas nos dias 0, 7, 14 e 21, pós-tratamento para análise quantitativa (OPG) e para análise qualitativa (coprocultura), foram utilizadas amostras nos dias 0, 14 e 21. A primeira coleta de sangue se deu no dia 0, a segunda e a terceira 24 e 72 horas após a primeira, respectivamente, a quarta e a quinta 7 e 14 dias após a primeira, dos quais foram analisados o hemograma, os níveis séricos de proteínas totais, albumina e globulinas, e a relação albumina/globulinas. Foi determinado o grau de anemia pelo método Famacha de cada animal em todos os momentos de coleta de amostras. O tratamento com closantel foi eficaz na redução da carga parasitária, principalmente Haemonchus contortus, nos ovinos avaliados. Por outro lado, houve resistência dos parasitas à ivermectina. Os dados de Famacha apresentaram correlação negativa com volume globular, leucócitos, hemoglobina, albumina, proteínas totais, globulinas e relação albumina/globulinas. O volume globular apresentou uma correlação forte e positiva com hemoglobina, albumina e proteínas totais. Os tratamentos com closantel e ivermectina não foram responsáveis por alterações consideráveis nos parâmetros hematológicos e bioquímicos avaliados.application/pdfhttp://repositorio.ufersa.edu.br/retrieve/725/kizzyMFMC_DISSERT.pdf.jpgporUniversidade Federal Rural do Semi-ÁridoPrograma de Pós-Graduação em Ciência AnimalUFERSABRCentro de Ciências Agrárias - CCACC-BY-SAinfo:eu-repo/semantics/openAccessSheep diseasesparasitary diseasesantihelminticsparasite resistanceDoenças de ovinosdoenças parasitáriasanti-helmínticosresistência parasitáriaCNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIAPerfil Hematológico e Bioquímico Sérico de Ovinos Infectados com Nematóides e Medicados com Ivermectina e ClosantelHematologiy And Serum Biochemical Panel Sheep Infected with Nematodes and Dosed with Ivermectin and Closantelinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisreponame:Biblioteca Digital de Teses e Dissertações da UFERSAinstname:Universidade Federal Rural do Semi-Árido (UFERSA)instacron:UFERSATEXTkizzyMFMC_DISSERT.pdf.txtkizzyMFMC_DISSERT.pdf.txtExtracted texttext/plain95637https://repositorio.ufersa.edu.br//bitstream/tede/327/3/kizzyMFMC_DISSERT.pdf.txt5fc158df193491b793fb7803fe2fee02MD53ORIGINALkizzyMFMC_DISSERT.pdfapplication/pdf774522https://repositorio.ufersa.edu.br//bitstream/tede/327/1/kizzyMFMC_DISSERT.pdfda3661ec2a393e4af5e31278032e04d2MD51THUMBNAILkizzyMFMC_DISSERT.pdf.jpgkizzyMFMC_DISSERT.pdf.jpgGenerated Thumbnailimage/jpeg3525https://repositorio.ufersa.edu.br//bitstream/tede/327/2/kizzyMFMC_DISSERT.pdf.jpg116fc7cc6c3b7f6ffc3ad62d6f69bcf8MD52tede/3272022-07-05 14:22:54.131oai:repositorio.ufersa.edu.br:tede/327Biblioteca Digital de Teses e Dissertaçõeshttps://repositorio.ufersa.edu.br/PUBhttp://bdtd.ufersa.edu.br/oai/requestdirecaosisbi@ufersa.edu.br|| direcaosisbi@ufersa.edu.bropendoar:2022-07-05T17:22:54Biblioteca Digital de Teses e Dissertações da UFERSA - Universidade Federal Rural do Semi-Árido (UFERSA)false |
dc.title.por.fl_str_mv |
Perfil Hematológico e Bioquímico Sérico de Ovinos Infectados com Nematóides e Medicados com Ivermectina e Closantel |
dc.title.alternative.eng.fl_str_mv |
Hematologiy And Serum Biochemical Panel Sheep Infected with Nematodes and Dosed with Ivermectin and Closantel |
title |
Perfil Hematológico e Bioquímico Sérico de Ovinos Infectados com Nematóides e Medicados com Ivermectina e Closantel |
spellingShingle |
Perfil Hematológico e Bioquímico Sérico de Ovinos Infectados com Nematóides e Medicados com Ivermectina e Closantel Costa, Kizzy Millenn de Freitas Mendonça Sheep diseases parasitary diseases antihelmintics parasite resistance Doenças de ovinos doenças parasitárias anti-helmínticos resistência parasitária CNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIA |
title_short |
Perfil Hematológico e Bioquímico Sérico de Ovinos Infectados com Nematóides e Medicados com Ivermectina e Closantel |
title_full |
Perfil Hematológico e Bioquímico Sérico de Ovinos Infectados com Nematóides e Medicados com Ivermectina e Closantel |
title_fullStr |
Perfil Hematológico e Bioquímico Sérico de Ovinos Infectados com Nematóides e Medicados com Ivermectina e Closantel |
title_full_unstemmed |
Perfil Hematológico e Bioquímico Sérico de Ovinos Infectados com Nematóides e Medicados com Ivermectina e Closantel |
title_sort |
Perfil Hematológico e Bioquímico Sérico de Ovinos Infectados com Nematóides e Medicados com Ivermectina e Closantel |
author |
Costa, Kizzy Millenn de Freitas Mendonça |
author_facet |
Costa, Kizzy Millenn de Freitas Mendonça |
author_role |
author |
dc.contributor.advisor1.fl_str_mv |
Ahid, Silvia Maria Mendes |
dc.contributor.advisor1Lattes.fl_str_mv |
http://lattes.cnpq.br/5525213637103948 |
dc.contributor.advisor-co1.fl_str_mv |
Blanco, Benito Soto |
dc.contributor.advisor-co1Lattes.fl_str_mv |
http://lattes.cnpq.br/5009042939501223 |
dc.contributor.referee1.fl_str_mv |
Vieira, Luiz da Silva |
dc.contributor.referee1Lattes.fl_str_mv |
http://lattes.cnpq.br/5556932562390291 |
dc.contributor.authorLattes.fl_str_mv |
http://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4594567E9 |
dc.contributor.author.fl_str_mv |
Costa, Kizzy Millenn de Freitas Mendonça |
contributor_str_mv |
Ahid, Silvia Maria Mendes Blanco, Benito Soto Vieira, Luiz da Silva |
dc.subject.eng.fl_str_mv |
Sheep diseases parasitary diseases antihelmintics parasite resistance |
topic |
Sheep diseases parasitary diseases antihelmintics parasite resistance Doenças de ovinos doenças parasitárias anti-helmínticos resistência parasitária CNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIA |
dc.subject.por.fl_str_mv |
Doenças de ovinos doenças parasitárias anti-helmínticos resistência parasitária |
dc.subject.cnpq.fl_str_mv |
CNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIA |
description |
Despite its known resistance, the sheep are subject to endoparasitoses, which are the main limiting factor for its production worldwide, especially in tropical regions. This study aims to evaluate the changes in parasitic load, serum biochemical and hematological panel, and Famacha scores of mixed-bred sheep naturally infected with nematodes and treated with ivermectin and closantel. The study was conducted at July 2010, in a farm in the municipality of Mossoró, Rio Grande do Norte state, Brazil. We selected 41 animals were divided into three groups: group I- control (without treatment), group II- treated with ivermectin (0.2 mg/kg), and Group III- treated with closantel (5 mg/kg). Stool samples were collected on days 0, 7, 14 and 21 after treatment for quantitative analysis (EPG) and qualitative analysis (stool culture), we used samples from days 0, 14 and 21. The first blood sample was given on day 0, the second and third 24 and 72 hours after the first, respectively the fourth and fifth 7 and 14 days after the first of which analyzed the blood count, serum total protein, albumin and globulins, and albumin/globulins ratio. Famacha scores were determined the degree of each animal at all times of sampling. Closantel administration was effective for the reduction of parasite counts, especially Haemonchus contortus, in evaluated sheep. On the other hand, there was parasite resistance to ivermectin. Famacha data showed negative correlation with packed cell volume, leukocytes, hemoglobin, albumin, total protein, globulin and albumin/globulin ratio. The packed cell volume showed a strong and positive correlation with hemoglobin, albumin and total protein. Treatment with ivermectin and closantel were not responsible for considerable changes in hematological and biochemical parameters evaluated. |
publishDate |
2011 |
dc.date.issued.fl_str_mv |
2011-09-08 |
dc.date.available.fl_str_mv |
2014-11-11 |
dc.date.accessioned.fl_str_mv |
2016-08-15T20:31:01Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/masterThesis |
format |
masterThesis |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
COSTA, Kizzy Millenn de Freitas Mendonça. Hematologiy And Serum Biochemical Panel Sheep Infected with Nematodes and Dosed with Ivermectin and Closantel. 2011. 56 f. Dissertação (Mestrado em Sanidade e Produção Animal) - Universidade Federal Rural do Semi-Árido, Mossoró, 2011. |
dc.identifier.uri.fl_str_mv |
https://repositorio.ufersa.edu.br/handle/tede/327 |
identifier_str_mv |
COSTA, Kizzy Millenn de Freitas Mendonça. Hematologiy And Serum Biochemical Panel Sheep Infected with Nematodes and Dosed with Ivermectin and Closantel. 2011. 56 f. Dissertação (Mestrado em Sanidade e Produção Animal) - Universidade Federal Rural do Semi-Árido, Mossoró, 2011. |
url |
https://repositorio.ufersa.edu.br/handle/tede/327 |
dc.language.iso.fl_str_mv |
por |
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por |
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CC-BY-SA info:eu-repo/semantics/openAccess |
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CC-BY-SA |
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openAccess |
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application/pdf |
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Universidade Federal Rural do Semi-Árido |
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Programa de Pós-Graduação em Ciência Animal |
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UFERSA |
dc.publisher.country.fl_str_mv |
BR |
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Centro de Ciências Agrárias - CCA |
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Universidade Federal Rural do Semi-Árido |
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