Interaction between active ruthenium complex [RuCl3(dppb)(VPy)] and phospholipid Langmuir monolayers: Effects on membrane electrical properties
Autor(a) principal: | |
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Data de Publicação: | 2016 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNIFESP |
Texto Completo: | https://repositorio.unifesp.br/handle/11600/56127 http://dx.doi.org/10.1016/j.cplett.2016.02.023 |
Resumo: | We report on the interaction between mer-[RuCl3(dppb)(VPy)] (dppb = 1,4-bis(diphenylphosphine)-butane and VPy=4-vinylpyridine) (RuVPy) and dipalmitoyl phosphatidyl serine (DPPS), in Langmuir and Langmuir-Blodgett (LB) films. Interaction of RuVPy with DPPS, which predominates in cancer cell membranes, should be weaker than for other phospholipids since RuVPy is less toxic to cancer cells than to healthy cells. Incorporation of RuVPy induced smaller changes in electrochemical properties of LB films of DPPS than for other phospholipids, but the same did not apply to surface pressure isotherms. This calls for caution in establishing correlations between effects from a single property and phenomena on cell membranes. (C) 2014 Elsevier B.V. All rights reserved. |
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Sandrino, B.Wrobel, E. C.Nobre, T. M.Caseli, Luciano [UNIFESP]Lazaro, S. R.Junior, A. C.Garcia, J. R.Oliveira Jr., O. N.Wohnrath, K.2020-07-22T13:23:15Z2020-07-22T13:23:15Z2016Chemical Physics Letters. Amsterdam, v. 649, p. 29-36, 2016.0009-2614https://repositorio.unifesp.br/handle/11600/56127http://dx.doi.org/10.1016/j.cplett.2016.02.02310.1016/j.cplett.2016.02.023WOS:000373274100006We report on the interaction between mer-[RuCl3(dppb)(VPy)] (dppb = 1,4-bis(diphenylphosphine)-butane and VPy=4-vinylpyridine) (RuVPy) and dipalmitoyl phosphatidyl serine (DPPS), in Langmuir and Langmuir-Blodgett (LB) films. Interaction of RuVPy with DPPS, which predominates in cancer cell membranes, should be weaker than for other phospholipids since RuVPy is less toxic to cancer cells than to healthy cells. Incorporation of RuVPy induced smaller changes in electrochemical properties of LB films of DPPS than for other phospholipids, but the same did not apply to surface pressure isotherms. This calls for caution in establishing correlations between effects from a single property and phenomena on cell membranes. (C) 2014 Elsevier B.V. All rights reserved.FAPESP (Brazil)CNPq (Brazil)CAPES (Brazil)nBioNet (Brazil)Univ Estadual Ponta Grossa, Appl Chem Program, BR-84035900 Ponta Grossa, PR, BrazilUniv Sao Paulo, Sao Carlos Inst Phys, BR-13560970 Sao Carlos, SP, BrazilUniv Fed Sao Paulo, Dept Exact Sci, BR-09972270 Diadema, SP, BrazilUniv Fed Sao Paulo, Dept Exact Sci, BR-09972270 Diadema, SP, BrazilWeb of Science29-36engElsevier Science BvChemical Physics LettersInteraction between active ruthenium complex [RuCl3(dppb)(VPy)] and phospholipid Langmuir monolayers: Effects on membrane electrical propertiesinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleAmsterdam649info:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP11600/561272021-09-28 16:45:39.797metadata only accessoai:repositorio.unifesp.br:11600/56127Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestopendoar:34652023-05-25T12:13:54.645382Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
dc.title.en.fl_str_mv |
Interaction between active ruthenium complex [RuCl3(dppb)(VPy)] and phospholipid Langmuir monolayers: Effects on membrane electrical properties |
title |
Interaction between active ruthenium complex [RuCl3(dppb)(VPy)] and phospholipid Langmuir monolayers: Effects on membrane electrical properties |
spellingShingle |
Interaction between active ruthenium complex [RuCl3(dppb)(VPy)] and phospholipid Langmuir monolayers: Effects on membrane electrical properties Sandrino, B. |
title_short |
Interaction between active ruthenium complex [RuCl3(dppb)(VPy)] and phospholipid Langmuir monolayers: Effects on membrane electrical properties |
title_full |
Interaction between active ruthenium complex [RuCl3(dppb)(VPy)] and phospholipid Langmuir monolayers: Effects on membrane electrical properties |
title_fullStr |
Interaction between active ruthenium complex [RuCl3(dppb)(VPy)] and phospholipid Langmuir monolayers: Effects on membrane electrical properties |
title_full_unstemmed |
Interaction between active ruthenium complex [RuCl3(dppb)(VPy)] and phospholipid Langmuir monolayers: Effects on membrane electrical properties |
title_sort |
Interaction between active ruthenium complex [RuCl3(dppb)(VPy)] and phospholipid Langmuir monolayers: Effects on membrane electrical properties |
author |
Sandrino, B. |
author_facet |
Sandrino, B. Wrobel, E. C. Nobre, T. M. Caseli, Luciano [UNIFESP] Lazaro, S. R. Junior, A. C. Garcia, J. R. Oliveira Jr., O. N. Wohnrath, K. |
author_role |
author |
author2 |
Wrobel, E. C. Nobre, T. M. Caseli, Luciano [UNIFESP] Lazaro, S. R. Junior, A. C. Garcia, J. R. Oliveira Jr., O. N. Wohnrath, K. |
author2_role |
author author author author author author author author |
dc.contributor.author.fl_str_mv |
Sandrino, B. Wrobel, E. C. Nobre, T. M. Caseli, Luciano [UNIFESP] Lazaro, S. R. Junior, A. C. Garcia, J. R. Oliveira Jr., O. N. Wohnrath, K. |
description |
We report on the interaction between mer-[RuCl3(dppb)(VPy)] (dppb = 1,4-bis(diphenylphosphine)-butane and VPy=4-vinylpyridine) (RuVPy) and dipalmitoyl phosphatidyl serine (DPPS), in Langmuir and Langmuir-Blodgett (LB) films. Interaction of RuVPy with DPPS, which predominates in cancer cell membranes, should be weaker than for other phospholipids since RuVPy is less toxic to cancer cells than to healthy cells. Incorporation of RuVPy induced smaller changes in electrochemical properties of LB films of DPPS than for other phospholipids, but the same did not apply to surface pressure isotherms. This calls for caution in establishing correlations between effects from a single property and phenomena on cell membranes. (C) 2014 Elsevier B.V. All rights reserved. |
publishDate |
2016 |
dc.date.issued.fl_str_mv |
2016 |
dc.date.accessioned.fl_str_mv |
2020-07-22T13:23:15Z |
dc.date.available.fl_str_mv |
2020-07-22T13:23:15Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
Chemical Physics Letters. Amsterdam, v. 649, p. 29-36, 2016. |
dc.identifier.uri.fl_str_mv |
https://repositorio.unifesp.br/handle/11600/56127 http://dx.doi.org/10.1016/j.cplett.2016.02.023 |
dc.identifier.issn.none.fl_str_mv |
0009-2614 |
dc.identifier.doi.none.fl_str_mv |
10.1016/j.cplett.2016.02.023 |
dc.identifier.wos.none.fl_str_mv |
WOS:000373274100006 |
identifier_str_mv |
Chemical Physics Letters. Amsterdam, v. 649, p. 29-36, 2016. 0009-2614 10.1016/j.cplett.2016.02.023 WOS:000373274100006 |
url |
https://repositorio.unifesp.br/handle/11600/56127 http://dx.doi.org/10.1016/j.cplett.2016.02.023 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.ispartof.none.fl_str_mv |
Chemical Physics Letters |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
29-36 |
dc.coverage.none.fl_str_mv |
Amsterdam |
dc.publisher.none.fl_str_mv |
Elsevier Science Bv |
publisher.none.fl_str_mv |
Elsevier Science Bv |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UNIFESP instname:Universidade Federal de São Paulo (UNIFESP) instacron:UNIFESP |
instname_str |
Universidade Federal de São Paulo (UNIFESP) |
instacron_str |
UNIFESP |
institution |
UNIFESP |
reponame_str |
Repositório Institucional da UNIFESP |
collection |
Repositório Institucional da UNIFESP |
repository.name.fl_str_mv |
Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP) |
repository.mail.fl_str_mv |
|
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1783460235880431616 |