Prevalence of Torque teno virus in healthy donors of Paraná State, southern Brazil

• Main Author: Mazzola,Jocimara Costa
• Publication Date: 2015
• Other Authors: Saito,Patrícia Keiko, Yamakawa,Roger Haruki, Watanabe,Maria Angélica Ehara, Silva Junior,Waldir Veríssimo da, Matta,Alessandra Cristina Gobbi, Borelli,Sueli Donizete
• Format: Article
• Language: eng
• Source: Revista brasileira de hematologia e hemoterapia (Online)
• Download full: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842015000500336
• topic: Torque teno virus; Blood donors polymerase; Chain reaction; Anellovirus; Virology

OBJECTIVE: To determine the prevalence of the Torque teno virus in healthy donors in the northern and northwestern regions of the state of Paraná, southern Brazil.METHODS: The Torque teno virus was detected by a nested polymerase chain reaction using a set of oligoprimers for the N22 region.RESULTS: The prevalence of the virus was 69% in 551 healthy blood donors in southern Brazil. There was no statistically significant difference between the presence of the virus and the variables gender, ethnicity and marital status. There was significant difference in the prevalence of the virus regarding the age of the donors (p-value = 0.024) with a higher incidence (74.7%) in 18- to 24-year-old donors.CONCLUSION: A high prevalence of Torque teno virus was observed in the population studied. Further studies are needed to elucidate the routes of contamination and the clinical implications of the virus in the healthy population.