Acute hemorrhagic leukoencephalitis mimicking herpes simplex encephalitis: case report

Detalhes bibliográficos
Autor(a) principal: Martins,Henrique Milhomem
Data de Publicação: 2004
Outros Autores: Teixeira-Jr,Antônio Lúcio, Lana-Peixoto,Marco Aurélio
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Arquivos de neuro-psiquiatria (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2004000100024
Resumo: Acute hemorrhagic leukoencephalitis (AHLE) is a more severe form of acute disseminated encephalomyelities (ADEM) characterized by a fulminant clinical course and the presence of hemorrhagic necrosis of the white matter. We report the case of a 57-year-old woman who developed delirium following a respiratory infection. Magnetic resonance imaging of the brain disclosed signal abnormalities in the frontal and temporal lobes, usually found in herpes simplex encephalitis (HSE). Gram stain, India ink and acid-fast bacilli staining were all negative in CSF as was a polymerase chain reaction (PCR) for herpes simplex virus. A diagnosis of AHLE was made and the patient was treated with IV methylprednisolone 1g/day for 5 days. Despite treatment, the patient developed several neurological sequelae compatible with the severity of her illness.
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spelling Acute hemorrhagic leukoencephalitis mimicking herpes simplex encephalitis: case reportacute disseminated encephalomyelitisacute hemorrhagic leukoencephalitisherpes simplex virus encephalitisAcute hemorrhagic leukoencephalitis (AHLE) is a more severe form of acute disseminated encephalomyelities (ADEM) characterized by a fulminant clinical course and the presence of hemorrhagic necrosis of the white matter. We report the case of a 57-year-old woman who developed delirium following a respiratory infection. Magnetic resonance imaging of the brain disclosed signal abnormalities in the frontal and temporal lobes, usually found in herpes simplex encephalitis (HSE). Gram stain, India ink and acid-fast bacilli staining were all negative in CSF as was a polymerase chain reaction (PCR) for herpes simplex virus. A diagnosis of AHLE was made and the patient was treated with IV methylprednisolone 1g/day for 5 days. Despite treatment, the patient developed several neurological sequelae compatible with the severity of her illness.Academia Brasileira de Neurologia - ABNEURO2004-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2004000100024Arquivos de Neuro-Psiquiatria v.62 n.1 2004reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/S0004-282X2004000100024info:eu-repo/semantics/openAccessMartins,Henrique MilhomemTeixeira-Jr,Antônio LúcioLana-Peixoto,Marco Aurélioeng2004-04-28T00:00:00Zoai:scielo:S0004-282X2004000100024Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2004-04-28T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse
dc.title.none.fl_str_mv Acute hemorrhagic leukoencephalitis mimicking herpes simplex encephalitis: case report
title Acute hemorrhagic leukoencephalitis mimicking herpes simplex encephalitis: case report
spellingShingle Acute hemorrhagic leukoencephalitis mimicking herpes simplex encephalitis: case report
Martins,Henrique Milhomem
acute disseminated encephalomyelitis
acute hemorrhagic leukoencephalitis
herpes simplex virus encephalitis
title_short Acute hemorrhagic leukoencephalitis mimicking herpes simplex encephalitis: case report
title_full Acute hemorrhagic leukoencephalitis mimicking herpes simplex encephalitis: case report
title_fullStr Acute hemorrhagic leukoencephalitis mimicking herpes simplex encephalitis: case report
title_full_unstemmed Acute hemorrhagic leukoencephalitis mimicking herpes simplex encephalitis: case report
title_sort Acute hemorrhagic leukoencephalitis mimicking herpes simplex encephalitis: case report
author Martins,Henrique Milhomem
author_facet Martins,Henrique Milhomem
Teixeira-Jr,Antônio Lúcio
Lana-Peixoto,Marco Aurélio
author_role author
author2 Teixeira-Jr,Antônio Lúcio
Lana-Peixoto,Marco Aurélio
author2_role author
author
dc.contributor.author.fl_str_mv Martins,Henrique Milhomem
Teixeira-Jr,Antônio Lúcio
Lana-Peixoto,Marco Aurélio
dc.subject.por.fl_str_mv acute disseminated encephalomyelitis
acute hemorrhagic leukoencephalitis
herpes simplex virus encephalitis
topic acute disseminated encephalomyelitis
acute hemorrhagic leukoencephalitis
herpes simplex virus encephalitis
description Acute hemorrhagic leukoencephalitis (AHLE) is a more severe form of acute disseminated encephalomyelities (ADEM) characterized by a fulminant clinical course and the presence of hemorrhagic necrosis of the white matter. We report the case of a 57-year-old woman who developed delirium following a respiratory infection. Magnetic resonance imaging of the brain disclosed signal abnormalities in the frontal and temporal lobes, usually found in herpes simplex encephalitis (HSE). Gram stain, India ink and acid-fast bacilli staining were all negative in CSF as was a polymerase chain reaction (PCR) for herpes simplex virus. A diagnosis of AHLE was made and the patient was treated with IV methylprednisolone 1g/day for 5 days. Despite treatment, the patient developed several neurological sequelae compatible with the severity of her illness.
publishDate 2004
dc.date.none.fl_str_mv 2004-03-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2004000100024
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2004000100024
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0004-282X2004000100024
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
dc.source.none.fl_str_mv Arquivos de Neuro-Psiquiatria v.62 n.1 2004
reponame:Arquivos de neuro-psiquiatria (Online)
instname:Academia Brasileira de Neurologia
instacron:ABNEURO
instname_str Academia Brasileira de Neurologia
instacron_str ABNEURO
institution ABNEURO
reponame_str Arquivos de neuro-psiquiatria (Online)
collection Arquivos de neuro-psiquiatria (Online)
repository.name.fl_str_mv Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia
repository.mail.fl_str_mv ||revista.arquivos@abneuro.org
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