Vitamina D em pediatria

• Autor(a) principal: Almeida, Ane Cristina Fayão
• Data de Publicação: 2022
• Outros Autores: Nogueira-de-Almeida, Carlos Alberto, Ferraz, Ivan Savioli
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: International Journal of Nutrology (Online)
• Texto Completo: https://ijn.zotarellifilhoscientificworks.com/index.php/ijn/article/view/126
• topic: Cholecalciferol; Infant; Vitamin D

Vitamin D (VD) is one of the fat-soluble vitamins. Its main sources in nature are diet and exposure to sunlight. Recent findings have shown that organs other than the kidney and liver are also able to synthesize VD metabolically active (calcitriol). Vitamin D deficiency (VDD) has been described almost 2.000 years ago and is classically related to diseases of the musculoskeletal system (especially rickets and osteomalacia). However, in recent years, VDD has been linked to disorders that affect other systems in the body, such as asthma and diabetes. In addition, an increase in the prevalence of VDD worldwide has been observed, even in countries with good insolation conditions. The most appropriate way to prevent VDD is by vitamin supplementation since there are no safe limits to sun exposure. The treatment of the VDD is mainly based on the replacement of the vitamin and it is indicated in the symptomatic forms (osteo-muscular symptoms) of its deficiency. VD intoxication is rare and observed in infants and young children who take high doses of VD in an acute way. This review article approaches these and other questions about VD, with particular emphasis on the particularities related to children and adolescents.