Complete genome sequence of a clinical Bordetella pertussis isolate from Brazil

Detalhes bibliográficos
Autor(a) principal: Andrade, Bruno Gabriel Nascimento
Data de Publicação: 2014
Outros Autores: Marin, Michel F. Abanto, Cambuy, Diego Duque, Fonseca, Erica Lourenço, Souza, Nadjila Ferreira, Vicente, Ana Carolina P.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/10415
Resumo: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Genética Molecular e Microorganismos. Rio de Janeiro, RJ, Brasil.
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spelling Andrade, Bruno Gabriel NascimentoMarin, Michel F. AbantoCambuy, Diego DuqueFonseca, Erica LourençoSouza, Nadjila FerreiraVicente, Ana Carolina P.2015-05-19T13:26:09Z2015-05-19T13:26:09Z2014ANDRADE, Bruno Gabriel N. et al. Complete genome sequence of a clinical Bordetella pertussis isolate from Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 109, n. 7, p. 952-954, nov. 2014.1678-8060https://www.arca.fiocruz.br/handle/icict/1041510.1590/0074-0276140288engFundação Oswaldo CruzBrasilptxP3Pandemic lineageVirulence factorsAntigenic variantFatores de VirulênciaBordetella pertussisComplete genome sequence of a clinical Bordetella pertussis isolate from Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Genética Molecular e Microorganismos. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Genética Molecular e Microorganismos. Rio de Janeiro, RJ, BrasilFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Genética Molecular e Microorganismos. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Genética Molecular e Microorganismos. Rio de Janeiro, RJ, BrasilLaboratório Central de Saúde Pública Dr Milton Sobral. Recife, PE, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Genética Molecular e Microorganismos. Rio de Janeiro, RJ, Brasil.There has been a resurgence in the number of pertussis cases in Brazil and around the world. Here, the genome of a clinical Bordetella pertussis strain (Bz181) that was recently isolated in Brazil is reported. Analysis of the virulence-associated genes defining the pre- and post-vaccination lineages revealed the presence of the prn2-ptxS1A-fim3B-ptxP3 allelic profile in Bz181, which is characteristic of the current pandemic lineage. A putative metallo-β-lactamase gene presenting all of the conserved zinc-binding motifs that characterise the catalytic site was identified, in addition to a multidrug efflux pump of the RND family that could confer resistance to erythromycin, which is the antibiotic of choice for treating pertussis disease.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txttext/plain1914https://www.arca.fiocruz.br/bitstream/icict/10415/1/license.txt7d48279ffeed55da8dfe2f8e81f3b81fMD51ORIGINALbruno_andradeetal_IOC_2014.pdfapplication/pdf735722https://www.arca.fiocruz.br/bitstream/icict/10415/2/bruno_andradeetal_IOC_2014.pdfd50898d8e274376c69fdf0e751b29e2fMD52TEXTbruno_andradeetal_IOC_2014.pdf.txtbruno_andradeetal_IOC_2014.pdf.txtExtracted texttext/plain13830https://www.arca.fiocruz.br/bitstream/icict/10415/3/bruno_andradeetal_IOC_2014.pdf.txt280cf2b865c9ab2221d17710e73ea096MD53icict/104152022-06-24 12:17:34.271oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352022-06-24T15:17:34Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Complete genome sequence of a clinical Bordetella pertussis isolate from Brazil
title Complete genome sequence of a clinical Bordetella pertussis isolate from Brazil
spellingShingle Complete genome sequence of a clinical Bordetella pertussis isolate from Brazil
Andrade, Bruno Gabriel Nascimento
Brasil
ptxP3
Pandemic lineage
Virulence factors
Antigenic variant
Fatores de Virulência
Bordetella pertussis
title_short Complete genome sequence of a clinical Bordetella pertussis isolate from Brazil
title_full Complete genome sequence of a clinical Bordetella pertussis isolate from Brazil
title_fullStr Complete genome sequence of a clinical Bordetella pertussis isolate from Brazil
title_full_unstemmed Complete genome sequence of a clinical Bordetella pertussis isolate from Brazil
title_sort Complete genome sequence of a clinical Bordetella pertussis isolate from Brazil
author Andrade, Bruno Gabriel Nascimento
author_facet Andrade, Bruno Gabriel Nascimento
Marin, Michel F. Abanto
Cambuy, Diego Duque
Fonseca, Erica Lourenço
Souza, Nadjila Ferreira
Vicente, Ana Carolina P.
author_role author
author2 Marin, Michel F. Abanto
Cambuy, Diego Duque
Fonseca, Erica Lourenço
Souza, Nadjila Ferreira
Vicente, Ana Carolina P.
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Andrade, Bruno Gabriel Nascimento
Marin, Michel F. Abanto
Cambuy, Diego Duque
Fonseca, Erica Lourenço
Souza, Nadjila Ferreira
Vicente, Ana Carolina P.
dc.subject.other.pt_BR.fl_str_mv Brasil
topic Brasil
ptxP3
Pandemic lineage
Virulence factors
Antigenic variant
Fatores de Virulência
Bordetella pertussis
dc.subject.en.pt_BR.fl_str_mv ptxP3
Pandemic lineage
Virulence factors
Antigenic variant
dc.subject.decs.pt_BR.fl_str_mv Fatores de Virulência
Bordetella pertussis
description Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Genética Molecular e Microorganismos. Rio de Janeiro, RJ, Brasil.
publishDate 2014
dc.date.issued.fl_str_mv 2014
dc.date.accessioned.fl_str_mv 2015-05-19T13:26:09Z
dc.date.available.fl_str_mv 2015-05-19T13:26:09Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv ANDRADE, Bruno Gabriel N. et al. Complete genome sequence of a clinical Bordetella pertussis isolate from Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 109, n. 7, p. 952-954, nov. 2014.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/10415
dc.identifier.issn.pt_BR.fl_str_mv 1678-8060
dc.identifier.doi.pt_BR.fl_str_mv 10.1590/0074-0276140288
identifier_str_mv ANDRADE, Bruno Gabriel N. et al. Complete genome sequence of a clinical Bordetella pertussis isolate from Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 109, n. 7, p. 952-954, nov. 2014.
1678-8060
10.1590/0074-0276140288
url https://www.arca.fiocruz.br/handle/icict/10415
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Fundação Oswaldo Cruz
publisher.none.fl_str_mv Fundação Oswaldo Cruz
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
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instacron:FIOCRUZ
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