Rotavirus strain surveillance for three years following the introduction of rotavirus vaccine into Belém, Brazil
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2015 |
| Outros Autores: | , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/34924 |
Resumo: | 2020-08-21 |
| id |
CRUZ_1d1b6b6340b220fa844252bf9a4d13c1 |
|---|---|
| oai_identifier_str |
oai:www.arca.fiocruz.br:icict/34924 |
| network_acronym_str |
CRUZ |
| network_name_str |
Repositório Institucional da FIOCRUZ (ARCA) |
| repository_id_str |
2135 |
| spelling |
Guerra, Sylvia F. S.Linhares, Alexandre C.Mascarenhas, Joana D'Arc P.Oliveira, AlessilvaJustino, Maria Cleonice A.Soares, Luana S.Müller, Elza CarolineBrasil, PatríciaTuboi, SuelyOrtega-Barria, EduardoColindres, Rómulo2019-08-21T14:08:34Z2019-08-21T14:08:34Z2015GUERRA, Sylvia F. S. et al. Rotavirus strain surveillance for three years following the introduction of rotavirus vaccine into Belém, Brazil. Journal of Medical Virology, v. 87, n. 8, p.1303-1310, Aug. 2015.0146-6615https://www.arca.fiocruz.br/handle/icict/3492410.1002/jmv.241831096-9071engWileyRotavirus strain surveillance for three years following the introduction of rotavirus vaccine into Belém, Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article2020-08-21Health Surveillance Secretariat. Evandro Chagas Institute. Belém, PA, Brazil.Health Surveillance Secretariat. Evandro Chagas Institute. Belém, PA, Brazil.Health Surveillance Secretariat. Evandro Chagas Institute. Belém, PA, Brazil.Health Surveillance Secretariat. Evandro Chagas Institute. Belém, PA, Brazil.Health Surveillance Secretariat. Evandro Chagas Institute. Belém, PA, Brazil.Health Surveillance Secretariat. Evandro Chagas Institute. Belém, PA, Brazil.Health Surveillance Secretariat. Evandro Chagas Institute. Belém, PA, Brazil.Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Rio de Janeiro, RJ, Brasil.GlaxoSmithKline. Rio de Janeiro, RJ, Brazil.GlaxoSmithKline. Panama, Panama.GlaxoSmithKline. Rio de Janeiro, RJ, Brazil.The monovalent human rotavirus (RV) vaccine, RIX4414 (Rotarix™, GlaxoSmithKline Biologicals) was introduced into Brazil's Expanded Program on Immunization in March 2006. One year after vaccine introduction, the G2P[4] strain was found to be predominant, with an apparent extinction of many non-G2 strains. This study investigated the diversity of circulating strains in the three years following RIX4414 introduction. Between May 2008 and May 2011, stool samples were collected from children aged ≥12 weeks who were hospitalized for severe lab confirmed RV-gastroenteritis (≥3 liquid or semi-liquid motions over a 24-h period for <14 days, requiring ≥1 overnight hospital stay and intravenous rehydration therapy) in Belém, Brazil. RV-gastroenteritis was detected by ELISA and the G- and P-types were determined by RT-PCR assays. During the first year of surveillance nucleotide sequencing was used for typing those samples not previously typed by RT-PCR. A total of 1,726 of 10,030 severe gastroentertis hospitalizations (17.2%) were due to severe RVGE. G2P[4] was detected in 57.2% of circulating strains over the whole study period, however it predominated during the first 20 months from May 2008 to January 2009. G1P[8] increased in the last part of the study period from May 2010 to May 2011 and represented 36.6% (112/306) of the circulating strains. G2P[4] was the predominant RV strain circulating during the first 20 months of the study, followed by G1P[8]. These findings probably reflect a natural fluctuation in RV strains over time, rather than a vaccine-induced selective pressure.RotavirusBelémBrazilGenotypesPost-vaccinationGastroenteritisinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83104https://www.arca.fiocruz.br/bitstream/icict/34924/1/license.txt79178e5f2a0eb066867a274556814938MD51ORIGINALve_Guerra_Sylvia_etal_INI_2015.pdfve_Guerra_Sylvia_etal_INI_2015.pdfapplication/pdf219563https://www.arca.fiocruz.br/bitstream/icict/34924/2/ve_Guerra_Sylvia_etal_INI_2015.pdf61eb12d683f73f061068fc9a2d8439beMD52TEXTve_Guerra_Sylvia_etal_INI_2015.pdf.txtve_Guerra_Sylvia_etal_INI_2015.pdf.txtExtracted texttext/plain40858https://www.arca.fiocruz.br/bitstream/icict/34924/3/ve_Guerra_Sylvia_etal_INI_2015.pdf.txt6fd411ec58331cf26353249cbec7ab3eMD53icict/349242021-03-24 16:32:35.614oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352021-03-24T19:32:35Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false |
| dc.title.pt_BR.fl_str_mv |
Rotavirus strain surveillance for three years following the introduction of rotavirus vaccine into Belém, Brazil |
| title |
Rotavirus strain surveillance for three years following the introduction of rotavirus vaccine into Belém, Brazil |
| spellingShingle |
Rotavirus strain surveillance for three years following the introduction of rotavirus vaccine into Belém, Brazil Guerra, Sylvia F. S. Rotavirus Belém Brazil Genotypes Post-vaccination Gastroenteritis |
| title_short |
Rotavirus strain surveillance for three years following the introduction of rotavirus vaccine into Belém, Brazil |
| title_full |
Rotavirus strain surveillance for three years following the introduction of rotavirus vaccine into Belém, Brazil |
| title_fullStr |
Rotavirus strain surveillance for three years following the introduction of rotavirus vaccine into Belém, Brazil |
| title_full_unstemmed |
Rotavirus strain surveillance for three years following the introduction of rotavirus vaccine into Belém, Brazil |
| title_sort |
Rotavirus strain surveillance for three years following the introduction of rotavirus vaccine into Belém, Brazil |
| author |
Guerra, Sylvia F. S. |
| author_facet |
Guerra, Sylvia F. S. Linhares, Alexandre C. Mascarenhas, Joana D'Arc P. Oliveira, Alessilva Justino, Maria Cleonice A. Soares, Luana S. Müller, Elza Caroline Brasil, Patrícia Tuboi, Suely Ortega-Barria, Eduardo Colindres, Rómulo |
| author_role |
author |
| author2 |
Linhares, Alexandre C. Mascarenhas, Joana D'Arc P. Oliveira, Alessilva Justino, Maria Cleonice A. Soares, Luana S. Müller, Elza Caroline Brasil, Patrícia Tuboi, Suely Ortega-Barria, Eduardo Colindres, Rómulo |
| author2_role |
author author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Guerra, Sylvia F. S. Linhares, Alexandre C. Mascarenhas, Joana D'Arc P. Oliveira, Alessilva Justino, Maria Cleonice A. Soares, Luana S. Müller, Elza Caroline Brasil, Patrícia Tuboi, Suely Ortega-Barria, Eduardo Colindres, Rómulo |
| dc.subject.en.pt_BR.fl_str_mv |
Rotavirus Belém Brazil Genotypes Post-vaccination Gastroenteritis |
| topic |
Rotavirus Belém Brazil Genotypes Post-vaccination Gastroenteritis |
| description |
2020-08-21 |
| publishDate |
2015 |
| dc.date.issued.fl_str_mv |
2015 |
| dc.date.accessioned.fl_str_mv |
2019-08-21T14:08:34Z |
| dc.date.available.fl_str_mv |
2019-08-21T14:08:34Z |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.citation.fl_str_mv |
GUERRA, Sylvia F. S. et al. Rotavirus strain surveillance for three years following the introduction of rotavirus vaccine into Belém, Brazil. Journal of Medical Virology, v. 87, n. 8, p.1303-1310, Aug. 2015. |
| dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/34924 |
| dc.identifier.issn.pt_BR.fl_str_mv |
0146-6615 |
| dc.identifier.doi.none.fl_str_mv |
10.1002/jmv.24183 |
| dc.identifier.eissn.none.fl_str_mv |
1096-9071 |
| identifier_str_mv |
GUERRA, Sylvia F. S. et al. Rotavirus strain surveillance for three years following the introduction of rotavirus vaccine into Belém, Brazil. Journal of Medical Virology, v. 87, n. 8, p.1303-1310, Aug. 2015. 0146-6615 10.1002/jmv.24183 1096-9071 |
| url |
https://www.arca.fiocruz.br/handle/icict/34924 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
| eu_rights_str_mv |
openAccess |
| dc.publisher.none.fl_str_mv |
Wiley |
| publisher.none.fl_str_mv |
Wiley |
| dc.source.none.fl_str_mv |
reponame:Repositório Institucional da FIOCRUZ (ARCA) instname:Fundação Oswaldo Cruz (FIOCRUZ) instacron:FIOCRUZ |
| instname_str |
Fundação Oswaldo Cruz (FIOCRUZ) |
| instacron_str |
FIOCRUZ |
| institution |
FIOCRUZ |
| reponame_str |
Repositório Institucional da FIOCRUZ (ARCA) |
| collection |
Repositório Institucional da FIOCRUZ (ARCA) |
| bitstream.url.fl_str_mv |
https://www.arca.fiocruz.br/bitstream/icict/34924/1/license.txt https://www.arca.fiocruz.br/bitstream/icict/34924/2/ve_Guerra_Sylvia_etal_INI_2015.pdf https://www.arca.fiocruz.br/bitstream/icict/34924/3/ve_Guerra_Sylvia_etal_INI_2015.pdf.txt |
| bitstream.checksum.fl_str_mv |
79178e5f2a0eb066867a274556814938 61eb12d683f73f061068fc9a2d8439be 6fd411ec58331cf26353249cbec7ab3e |
| bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 MD5 |
| repository.name.fl_str_mv |
Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ) |
| repository.mail.fl_str_mv |
repositorio.arca@fiocruz.br |
| _version_ |
1798324654215004160 |