Bioactivity of the compounds isolated from Blepharocalyx salicifolius

Detalhes bibliográficos
Autor(a) principal: Siqueira Filho, Ezequias Pessoa de
Data de Publicação: 2012
Outros Autores: Oliveira, Djalma Menezes de, Johann, Susana, Cisalpino, Patrícia Silva, Cota, Betania Barros, Rabello, Ana Lúcia Teles, Alves, Tânia Maria de Almeida, Zani, Carlos Leomar
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/7894
Resumo: Fundação Oswaldo Cruz. Centro de Pesquisa René Rachou. Belo Horizonte, MG, Brazil
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spelling Siqueira Filho, Ezequias Pessoa deOliveira, Djalma Menezes deJohann, SusanaCisalpino, Patrícia SilvaCota, Betania BarrosRabello, Ana Lúcia TelesAlves, Tânia Maria de AlmeidaZani, Carlos Leomar2014-07-09T18:31:16Z2014-07-09T18:31:16Z2012Siqueira Filho, Ezequias Pessoa et al. Bioactivity of the compounds isolated from Blepharocalyx salicifolius. Revista Brasileira de Farmacognosia, 21(4): 645-651, 2011.0102-695Xhttps://www.arca.fiocruz.br/handle/icict/789410.1590/S0102-695X2011005000111engSociedade Brasileira de FarmacognosiaBioactivity of the compounds isolated from Blepharocalyx salicifoliusinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Centro de Pesquisa René Rachou. Belo Horizonte, MG, BrazilUniversidade Estadual do Sudoeste de Bahia. Jequié, BA, BrazilUniversidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Belo Horizonte, MG, BrazilUniversidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Belo Horizonte, MG, BrazilFundação Oswaldo Cruz. Centro de Pesquisa René Rachou. Belo Horizonte, MG, BrazilFundação Oswaldo Cruz. Centro de Pesquisa René Rachou. Belo Horizonte, MG, BrazilFundação Oswaldo Cruz. Centro de Pesquisa René Rachou. Belo Horizonte, MG, BrazilFundação Oswaldo Cruz. Centro de Pesquisa René Rachou. Belo Horizonte, MG, BrazilBlepharocalyx salicifolius (Kunth) O. Berg, Myrtaceae, is an endemic species that occurs at Southern America. This species was studied to intend to isolation of the active compounds that could be used in vitro model against leishmaniosis, tumoral cell and paracoccidioidomycosis. After Gel Permeation Chromatography, the ethanolic extract from leaves yielded sixteen fractions. Five compounds were isolated and assayed, showing activity against tumoral cells, from 3.33 to 12.83 µg.mL-1; Leishmania (Leishmania) amazonensis from 2.19 to 20.80 µg.mL-1 and Paracoccidioides brasiliensis from 3.10 to 12.5 µg.mL-1.biological assaysBlepharocalyx salicifoliuschalcone, flavonoidMyrtaceaetriterpeneinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINALioactivity of the compounds isolated from Blepharocalyx salicifolius.pdfioactivity of the compounds isolated from Blepharocalyx salicifolius.pdfapplication/pdf1125190https://www.arca.fiocruz.br/bitstream/icict/7894/1/ioactivity%20of%20the%20compounds%20isolated%20from%20Blepharocalyx%20salicifolius.pdf5f19515155208f24c24e17d3cfde1f82MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81914https://www.arca.fiocruz.br/bitstream/icict/7894/2/license.txt7d48279ffeed55da8dfe2f8e81f3b81fMD52TEXTioactivity of the compounds isolated from Blepharocalyx salicifolius.pdf.txtioactivity of the compounds isolated from Blepharocalyx salicifolius.pdf.txtExtracted texttext/plain7https://www.arca.fiocruz.br/bitstream/icict/7894/3/ioactivity%20of%20the%20compounds%20isolated%20from%20Blepharocalyx%20salicifolius.pdf.txt212b0306580d4f0044d18f9a3edcc832MD53icict/78942018-04-06 11:25:52.542oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352018-04-06T14:25:52Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Bioactivity of the compounds isolated from Blepharocalyx salicifolius
title Bioactivity of the compounds isolated from Blepharocalyx salicifolius
spellingShingle Bioactivity of the compounds isolated from Blepharocalyx salicifolius
Siqueira Filho, Ezequias Pessoa de
biological assays
Blepharocalyx salicifolius
chalcone, flavonoid
Myrtaceae
triterpene
title_short Bioactivity of the compounds isolated from Blepharocalyx salicifolius
title_full Bioactivity of the compounds isolated from Blepharocalyx salicifolius
title_fullStr Bioactivity of the compounds isolated from Blepharocalyx salicifolius
title_full_unstemmed Bioactivity of the compounds isolated from Blepharocalyx salicifolius
title_sort Bioactivity of the compounds isolated from Blepharocalyx salicifolius
author Siqueira Filho, Ezequias Pessoa de
author_facet Siqueira Filho, Ezequias Pessoa de
Oliveira, Djalma Menezes de
Johann, Susana
Cisalpino, Patrícia Silva
Cota, Betania Barros
Rabello, Ana Lúcia Teles
Alves, Tânia Maria de Almeida
Zani, Carlos Leomar
author_role author
author2 Oliveira, Djalma Menezes de
Johann, Susana
Cisalpino, Patrícia Silva
Cota, Betania Barros
Rabello, Ana Lúcia Teles
Alves, Tânia Maria de Almeida
Zani, Carlos Leomar
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Siqueira Filho, Ezequias Pessoa de
Oliveira, Djalma Menezes de
Johann, Susana
Cisalpino, Patrícia Silva
Cota, Betania Barros
Rabello, Ana Lúcia Teles
Alves, Tânia Maria de Almeida
Zani, Carlos Leomar
dc.subject.en.pt_BR.fl_str_mv biological assays
Blepharocalyx salicifolius
chalcone, flavonoid
Myrtaceae
triterpene
topic biological assays
Blepharocalyx salicifolius
chalcone, flavonoid
Myrtaceae
triterpene
description Fundação Oswaldo Cruz. Centro de Pesquisa René Rachou. Belo Horizonte, MG, Brazil
publishDate 2012
dc.date.issued.fl_str_mv 2012
dc.date.accessioned.fl_str_mv 2014-07-09T18:31:16Z
dc.date.available.fl_str_mv 2014-07-09T18:31:16Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv Siqueira Filho, Ezequias Pessoa et al. Bioactivity of the compounds isolated from Blepharocalyx salicifolius. Revista Brasileira de Farmacognosia, 21(4): 645-651, 2011.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/7894
dc.identifier.issn.none.fl_str_mv 0102-695X
dc.identifier.doi.none.fl_str_mv 10.1590/S0102-695X2011005000111
identifier_str_mv Siqueira Filho, Ezequias Pessoa et al. Bioactivity of the compounds isolated from Blepharocalyx salicifolius. Revista Brasileira de Farmacognosia, 21(4): 645-651, 2011.
0102-695X
10.1590/S0102-695X2011005000111
url https://www.arca.fiocruz.br/handle/icict/7894
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Sociedade Brasileira de Farmacognosia
publisher.none.fl_str_mv Sociedade Brasileira de Farmacognosia
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
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instname_str Fundação Oswaldo Cruz (FIOCRUZ)
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