Bioactivity of the compounds isolated from Blepharocalyx salicifolius

Detalhes bibliográficos
Autor(a) principal: Siqueira,Ezequias P.
Data de Publicação: 2011
Outros Autores: Oliveira,Djalma M., Johann,Susana, Cisalpino,Patrícia S., Cota,Betania B., Rabello,Ana, Alves,Tânia M. A., Zani,Carlos L.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista Brasileira de Farmacognosia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2011000400013
Resumo: Blepharocalyx salicifolius (Kunth) O. Berg, Myrtaceae, is an endemic species that occurs at Southern America. This species was studied to intend to isolation of the active compounds that could be used in vitro model against leishmaniosis, tumoral cell and paracoccidioidomycosis. After Gel Permeation Chromatography, the ethanolic extract from leaves yielded sixteen fractions. Five compounds were isolated and assayed, showing activity against tumoral cells, from 3.33 to 12.83 µg.mL-1; Leishmania (Leishmania) amazonensis from 2.19 to 20.80 µg.mL-1 and Paracoccidioides brasiliensis from 3.10 to 12.5 µg.mL-1.
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spelling Bioactivity of the compounds isolated from Blepharocalyx salicifoliusbiological assaysBlepharocalyx salicifoliuschalconeflavonoidMyrtaceaetriterpeneBlepharocalyx salicifolius (Kunth) O. Berg, Myrtaceae, is an endemic species that occurs at Southern America. This species was studied to intend to isolation of the active compounds that could be used in vitro model against leishmaniosis, tumoral cell and paracoccidioidomycosis. After Gel Permeation Chromatography, the ethanolic extract from leaves yielded sixteen fractions. Five compounds were isolated and assayed, showing activity against tumoral cells, from 3.33 to 12.83 µg.mL-1; Leishmania (Leishmania) amazonensis from 2.19 to 20.80 µg.mL-1 and Paracoccidioides brasiliensis from 3.10 to 12.5 µg.mL-1.Sociedade Brasileira de Farmacognosia2011-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2011000400013Revista Brasileira de Farmacognosia v.21 n.4 2011reponame:Revista Brasileira de Farmacognosia (Online)instname:Sociedade Brasileira de Farmacognosia (SBFgnosia)instacron:SBFGNOSIA10.1590/S0102-695X2011005000111info:eu-repo/semantics/openAccessSiqueira,Ezequias P.Oliveira,Djalma M.Johann,SusanaCisalpino,Patrícia S.Cota,Betania B.Rabello,AnaAlves,Tânia M. A.Zani,Carlos L.eng2011-08-15T00:00:00Zoai:scielo:S0102-695X2011000400013Revistahttp://www.sbfgnosia.org.br/revista/https://old.scielo.br/oai/scielo-oai.phprbgnosia@ltf.ufpb.br1981-528X0102-695Xopendoar:2011-08-15T00:00Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia)false
dc.title.none.fl_str_mv Bioactivity of the compounds isolated from Blepharocalyx salicifolius
title Bioactivity of the compounds isolated from Blepharocalyx salicifolius
spellingShingle Bioactivity of the compounds isolated from Blepharocalyx salicifolius
Siqueira,Ezequias P.
biological assays
Blepharocalyx salicifolius
chalcone
flavonoid
Myrtaceae
triterpene
title_short Bioactivity of the compounds isolated from Blepharocalyx salicifolius
title_full Bioactivity of the compounds isolated from Blepharocalyx salicifolius
title_fullStr Bioactivity of the compounds isolated from Blepharocalyx salicifolius
title_full_unstemmed Bioactivity of the compounds isolated from Blepharocalyx salicifolius
title_sort Bioactivity of the compounds isolated from Blepharocalyx salicifolius
author Siqueira,Ezequias P.
author_facet Siqueira,Ezequias P.
Oliveira,Djalma M.
Johann,Susana
Cisalpino,Patrícia S.
Cota,Betania B.
Rabello,Ana
Alves,Tânia M. A.
Zani,Carlos L.
author_role author
author2 Oliveira,Djalma M.
Johann,Susana
Cisalpino,Patrícia S.
Cota,Betania B.
Rabello,Ana
Alves,Tânia M. A.
Zani,Carlos L.
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Siqueira,Ezequias P.
Oliveira,Djalma M.
Johann,Susana
Cisalpino,Patrícia S.
Cota,Betania B.
Rabello,Ana
Alves,Tânia M. A.
Zani,Carlos L.
dc.subject.por.fl_str_mv biological assays
Blepharocalyx salicifolius
chalcone
flavonoid
Myrtaceae
triterpene
topic biological assays
Blepharocalyx salicifolius
chalcone
flavonoid
Myrtaceae
triterpene
description Blepharocalyx salicifolius (Kunth) O. Berg, Myrtaceae, is an endemic species that occurs at Southern America. This species was studied to intend to isolation of the active compounds that could be used in vitro model against leishmaniosis, tumoral cell and paracoccidioidomycosis. After Gel Permeation Chromatography, the ethanolic extract from leaves yielded sixteen fractions. Five compounds were isolated and assayed, showing activity against tumoral cells, from 3.33 to 12.83 µg.mL-1; Leishmania (Leishmania) amazonensis from 2.19 to 20.80 µg.mL-1 and Paracoccidioides brasiliensis from 3.10 to 12.5 µg.mL-1.
publishDate 2011
dc.date.none.fl_str_mv 2011-08-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2011000400013
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2011000400013
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0102-695X2011005000111
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Farmacognosia
publisher.none.fl_str_mv Sociedade Brasileira de Farmacognosia
dc.source.none.fl_str_mv Revista Brasileira de Farmacognosia v.21 n.4 2011
reponame:Revista Brasileira de Farmacognosia (Online)
instname:Sociedade Brasileira de Farmacognosia (SBFgnosia)
instacron:SBFGNOSIA
instname_str Sociedade Brasileira de Farmacognosia (SBFgnosia)
instacron_str SBFGNOSIA
institution SBFGNOSIA
reponame_str Revista Brasileira de Farmacognosia (Online)
collection Revista Brasileira de Farmacognosia (Online)
repository.name.fl_str_mv Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia)
repository.mail.fl_str_mv rbgnosia@ltf.ufpb.br
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