Correlation between TH1 response standard cytokines as biomarkers in patients with the delta virus in the western Brazilian Amazon.

Detalhes bibliográficos
Autor(a) principal: Nicolete., Larissa Deadame de Figueiredo.
Data de Publicação: 2016
Outros Autores: Borzacov., Lourdes Maria Pinheiro., Vieira., Deusilene Souza., Nicolete., Roberto., Salcedo., Juan Miguel Villalobos.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/27197
Resumo: Universidade Federal de Rondônia. Programa de Pós-Graduação em Biologia Experimental. Porto Velho, RO, Brasil. / Centro de Pesquisa em Medicina Tropical, Porto Velho, RO, Brasil. / Fundação Oswaldo Cruz. Laboratório de Biotecnologia Aplicada à Saúde. Porto Velho, RO, Brasil.
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spelling Nicolete., Larissa Deadame de Figueiredo.Borzacov., Lourdes Maria Pinheiro.Vieira., Deusilene Souza.Nicolete., Roberto.Salcedo., Juan Miguel Villalobos.2018-06-29T15:23:47Z2018-06-29T15:23:47Z2016SALCEDO, Juan Miguel Villalobos, et all. Correlation between TH1 response standard cytokines as biomarkers in patients with the delta virus in the western Brazilian Amazon. Memórias do Instituto Oswaldo Cruz, vol.111, p.275-276, 2016.0074-0276https://www.arca.fiocruz.br/handle/icict/271971678-8060engMemórias do Instituto Oswaldo Cruz.Correlation between TH1 response standard cytokines as biomarkers in patients with the delta virus in the western Brazilian Amazon.info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal de Rondônia. Programa de Pós-Graduação em Biologia Experimental. Porto Velho, RO, Brasil. / Centro de Pesquisa em Medicina Tropical, Porto Velho, RO, Brasil. / Fundação Oswaldo Cruz. Laboratório de Biotecnologia Aplicada à Saúde. Porto Velho, RO, Brasil.Centro de Pesquisa em Medicina Tropical, Porto Velho, RO, Brasil.Universidade Federal de Rondônia. Programa de Pós-Graduação em Biologia Experimental. Porto Velho, RO, Brasil. / Centro de Pesquisa em Medicina Tropical, Porto Velho, RO, Brasil. / Fundação Oswaldo Cruz. Laboratório de Biotecnologia Aplicada à Saúde. Porto Velho, RO, Brasil.Universidade Federal de Rondônia. Programa de Pós-Graduação em Biologia Experimental. Porto Velho, RO, Brasil. / Fundação Oswaldo Cruz. Laboratório de Biotecnologia Aplicada à Saúde. Porto Velho, RO, Brasil.Universidade Federal de Rondônia. Programa de Pós-Graduação em Biologia Experimental. Porto Velho, RO, Brasil. / Centro de Pesquisa em Medicina Tropical, Porto Velho, RO, Brasil. / Fundação Oswaldo Cruz. Laboratório de Biotecnologia Aplicada à Saúde. Porto Velho, RO, Brasil.Hepatitis D virus (HDV) is endemic in the Amazon Region and its pathophysiology is the most severe among viral hepatitis. Treatment is performed with pegylated interferon and the immune response appears to be important for infection control. HDV patients were studied: untreated and polymerase chain reaction (PCR) positive (n = 9), anti-HDV positive and PCR negative (n = 8), and responders to treatment (n = 12). The cytokines, interleukin (IL)-2 (p = 0.0008) and IL-12 (p = 0.02) were differentially expressed among the groups and were also correlated (p = 0.0143). Future studies will be conducted with patients at different stages of treatment, associating the viral load with serum cytokines produced, thereby attempting to establish a prognostic indicator of the infection.HDVTH1 cytokinesPatients treatedinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/27197/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALCorrelation between TH1 response standard cytokines as biomarkers in patients with the delta virus in the western Brazilian Amazon.pdfCorrelation between TH1 response standard cytokines as biomarkers in patients with the delta virus in the western Brazilian Amazon.pdfapplication/pdf262533https://www.arca.fiocruz.br/bitstream/icict/27197/2/Correlation%20between%20TH1%20response%20standard%20cytokines%20as%20biomarkers%20in%20patients%20with%20the%20delta%20virus%20in%20the%20western%20Brazilian%20Amazon.pdf932c5aa0ec4403bc9571c8f542f53df7MD52TEXTCorrelation between TH1 response standard cytokines as biomarkers in patients with the delta virus in the western Brazilian Amazon.pdf.txtCorrelation between TH1 response standard cytokines as biomarkers in patients with the delta virus in the western Brazilian Amazon.pdf.txtExtracted texttext/plain10778https://www.arca.fiocruz.br/bitstream/icict/27197/3/Correlation%20between%20TH1%20response%20standard%20cytokines%20as%20biomarkers%20in%20patients%20with%20the%20delta%20virus%20in%20the%20western%20Brazilian%20Amazon.pdf.txt4d2f401c976b51983cf7c26fe03f6d7fMD53icict/271972018-08-15 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dc.title.pt_BR.fl_str_mv Correlation between TH1 response standard cytokines as biomarkers in patients with the delta virus in the western Brazilian Amazon.
title Correlation between TH1 response standard cytokines as biomarkers in patients with the delta virus in the western Brazilian Amazon.
spellingShingle Correlation between TH1 response standard cytokines as biomarkers in patients with the delta virus in the western Brazilian Amazon.
Nicolete., Larissa Deadame de Figueiredo.
HDV
TH1 cytokines
Patients treated
title_short Correlation between TH1 response standard cytokines as biomarkers in patients with the delta virus in the western Brazilian Amazon.
title_full Correlation between TH1 response standard cytokines as biomarkers in patients with the delta virus in the western Brazilian Amazon.
title_fullStr Correlation between TH1 response standard cytokines as biomarkers in patients with the delta virus in the western Brazilian Amazon.
title_full_unstemmed Correlation between TH1 response standard cytokines as biomarkers in patients with the delta virus in the western Brazilian Amazon.
title_sort Correlation between TH1 response standard cytokines as biomarkers in patients with the delta virus in the western Brazilian Amazon.
author Nicolete., Larissa Deadame de Figueiredo.
author_facet Nicolete., Larissa Deadame de Figueiredo.
Borzacov., Lourdes Maria Pinheiro.
Vieira., Deusilene Souza.
Nicolete., Roberto.
Salcedo., Juan Miguel Villalobos.
author_role author
author2 Borzacov., Lourdes Maria Pinheiro.
Vieira., Deusilene Souza.
Nicolete., Roberto.
Salcedo., Juan Miguel Villalobos.
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Nicolete., Larissa Deadame de Figueiredo.
Borzacov., Lourdes Maria Pinheiro.
Vieira., Deusilene Souza.
Nicolete., Roberto.
Salcedo., Juan Miguel Villalobos.
dc.subject.en.pt_BR.fl_str_mv HDV
TH1 cytokines
Patients treated
topic HDV
TH1 cytokines
Patients treated
description Universidade Federal de Rondônia. Programa de Pós-Graduação em Biologia Experimental. Porto Velho, RO, Brasil. / Centro de Pesquisa em Medicina Tropical, Porto Velho, RO, Brasil. / Fundação Oswaldo Cruz. Laboratório de Biotecnologia Aplicada à Saúde. Porto Velho, RO, Brasil.
publishDate 2016
dc.date.issued.fl_str_mv 2016
dc.date.accessioned.fl_str_mv 2018-06-29T15:23:47Z
dc.date.available.fl_str_mv 2018-06-29T15:23:47Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv SALCEDO, Juan Miguel Villalobos, et all. Correlation between TH1 response standard cytokines as biomarkers in patients with the delta virus in the western Brazilian Amazon. Memórias do Instituto Oswaldo Cruz, vol.111, p.275-276, 2016.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/27197
dc.identifier.issn.pt_BR.fl_str_mv 0074-0276
dc.identifier.eissn.none.fl_str_mv 1678-8060
identifier_str_mv SALCEDO, Juan Miguel Villalobos, et all. Correlation between TH1 response standard cytokines as biomarkers in patients with the delta virus in the western Brazilian Amazon. Memórias do Instituto Oswaldo Cruz, vol.111, p.275-276, 2016.
0074-0276
1678-8060
url https://www.arca.fiocruz.br/handle/icict/27197
dc.language.iso.fl_str_mv eng
language eng
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eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Memórias do Instituto Oswaldo Cruz.
publisher.none.fl_str_mv Memórias do Instituto Oswaldo Cruz.
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
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instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
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