Distinct ultrastructural aspects in different biopsies of a single patient with diffuse cutaneous leishmaniasis

Detalhes bibliográficos
Autor(a) principal: Bittencourt, Achilea Candida Lisboa
Data de Publicação: 1990
Outros Autores: Freitas, Luiz Antonio Rodrigues de, Pompeu, Margarida Maria de Lima, Vieira, Maria Lucia, Barral, Aldina Maria Prado
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/7910
Resumo: Universidade Federal da Bahia. Hospital Universitário Prof. Edgard Santos. Departamento de Anatomia Patologica. Salvador, BA, Brasil.
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spelling Bittencourt, Achilea Candida LisboaFreitas, Luiz Antonio Rodrigues dePompeu, Margarida Maria de LimaVieira, Maria LuciaBarral, Aldina Maria Prado2014-07-10T17:47:54Z2014-07-10T17:47:54Z1990BITTENCOURT, Achilea Candida Lisboa et al. Distinct ultrastructural aspects in different biopsies of a single patient with diffuse cutaneous leishmaniasis. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 85, n. 1, p. 53-59, 1990.0074-0276https://www.arca.fiocruz.br/handle/icict/791010.1590/S0074-02761990000100008engFiocruzDistinct ultrastructural aspects in different biopsies of a single patient with diffuse cutaneous leishmaniasisinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal da Bahia. Hospital Universitário Prof. Edgard Santos. Departamento de Anatomia Patologica. Salvador, BA, Brasil.Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil.Universidade Federal do Ceará. Departamento de Patologia. Fortaleza, CE, Brasil.Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil.Universidade Federal da Bahia. Hospital Universitário Prof. Edgard Santos. Laboratório de Imunologia. Salvador, BA, Brasil.The authors investigated the relation between parasites and host-cells in active and regressed lesions of a patient with diffuse cutaneous leishmaniasis, evaluating the frequency of different cell types, and the location and integrity of amastigotes. No correlation was found between parasite integrity and size of parasitophorous vacuoles. They observed ultrastructural findings characterizing a cell mediated immune response: macrophages lysis, parasitic destruction inside macrophages, close contact between parasitized macrophages and lymphocytes and between parasites and lymphocytes, lymphocytic infiltration and fibrosis. They suggest that in DCL there is a limited cellular immune response, although insufficient to control infection.Diffuse cutaneous leishmaniasisHuman leishmaniasisLeishmaniaSkin biopsieLeishmaniose/patologiaPele/ultraestruturaAdultoAnimaisBiópsiaHumanosLeishmania/isolamento & purificaçãoLeishmaniose/parasitologiaMacrófagos/parasitologiaMacrófagos/ultraestruturaMasculinoinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINALBittencourt AL Distinct ultrastructural....pdfBittencourt AL Distinct ultrastructural....pdfapplication/pdf423500https://www.arca.fiocruz.br/bitstream/icict/7910/1/Bittencourt%20AL%20Distinct%20ultrastructural....pdfa4551824779109fe4860f5d01ac1e052MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81914https://www.arca.fiocruz.br/bitstream/icict/7910/2/license.txt7d48279ffeed55da8dfe2f8e81f3b81fMD52TEXTBittencourt AL Distinct ultrastructural....pdf.txtBittencourt AL Distinct ultrastructural....pdf.txtExtracted texttext/plain7https://www.arca.fiocruz.br/bitstream/icict/7910/3/Bittencourt%20AL%20Distinct%20ultrastructural....pdf.txt212b0306580d4f0044d18f9a3edcc832MD53icict/79102023-03-15 14:33:16.213oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-03-15T17:33:16Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Distinct ultrastructural aspects in different biopsies of a single patient with diffuse cutaneous leishmaniasis
title Distinct ultrastructural aspects in different biopsies of a single patient with diffuse cutaneous leishmaniasis
spellingShingle Distinct ultrastructural aspects in different biopsies of a single patient with diffuse cutaneous leishmaniasis
Bittencourt, Achilea Candida Lisboa
Diffuse cutaneous leishmaniasis
Human leishmaniasis
Leishmania
Skin biopsie
Leishmaniose/patologia
Pele/ultraestrutura
Adulto
Animais
Biópsia
Humanos
Leishmania/isolamento & purificação
Leishmaniose/parasitologia
Macrófagos/parasitologia
Macrófagos/ultraestrutura
Masculino
title_short Distinct ultrastructural aspects in different biopsies of a single patient with diffuse cutaneous leishmaniasis
title_full Distinct ultrastructural aspects in different biopsies of a single patient with diffuse cutaneous leishmaniasis
title_fullStr Distinct ultrastructural aspects in different biopsies of a single patient with diffuse cutaneous leishmaniasis
title_full_unstemmed Distinct ultrastructural aspects in different biopsies of a single patient with diffuse cutaneous leishmaniasis
title_sort Distinct ultrastructural aspects in different biopsies of a single patient with diffuse cutaneous leishmaniasis
author Bittencourt, Achilea Candida Lisboa
author_facet Bittencourt, Achilea Candida Lisboa
Freitas, Luiz Antonio Rodrigues de
Pompeu, Margarida Maria de Lima
Vieira, Maria Lucia
Barral, Aldina Maria Prado
author_role author
author2 Freitas, Luiz Antonio Rodrigues de
Pompeu, Margarida Maria de Lima
Vieira, Maria Lucia
Barral, Aldina Maria Prado
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Bittencourt, Achilea Candida Lisboa
Freitas, Luiz Antonio Rodrigues de
Pompeu, Margarida Maria de Lima
Vieira, Maria Lucia
Barral, Aldina Maria Prado
dc.subject.en.pt_BR.fl_str_mv Diffuse cutaneous leishmaniasis
Human leishmaniasis
Leishmania
Skin biopsie
topic Diffuse cutaneous leishmaniasis
Human leishmaniasis
Leishmania
Skin biopsie
Leishmaniose/patologia
Pele/ultraestrutura
Adulto
Animais
Biópsia
Humanos
Leishmania/isolamento & purificação
Leishmaniose/parasitologia
Macrófagos/parasitologia
Macrófagos/ultraestrutura
Masculino
dc.subject.decs.pt_BR.fl_str_mv Leishmaniose/patologia
Pele/ultraestrutura
Adulto
Animais
Biópsia
Humanos
Leishmania/isolamento & purificação
Leishmaniose/parasitologia
Macrófagos/parasitologia
Macrófagos/ultraestrutura
Masculino
description Universidade Federal da Bahia. Hospital Universitário Prof. Edgard Santos. Departamento de Anatomia Patologica. Salvador, BA, Brasil.
publishDate 1990
dc.date.issued.fl_str_mv 1990
dc.date.accessioned.fl_str_mv 2014-07-10T17:47:54Z
dc.date.available.fl_str_mv 2014-07-10T17:47:54Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv BITTENCOURT, Achilea Candida Lisboa et al. Distinct ultrastructural aspects in different biopsies of a single patient with diffuse cutaneous leishmaniasis. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 85, n. 1, p. 53-59, 1990.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/7910
dc.identifier.issn.none.fl_str_mv 0074-0276
dc.identifier.doi.pt_BR.fl_str_mv 10.1590/S0074-02761990000100008
identifier_str_mv BITTENCOURT, Achilea Candida Lisboa et al. Distinct ultrastructural aspects in different biopsies of a single patient with diffuse cutaneous leishmaniasis. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 85, n. 1, p. 53-59, 1990.
0074-0276
10.1590/S0074-02761990000100008
url https://www.arca.fiocruz.br/handle/icict/7910
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Fiocruz
publisher.none.fl_str_mv Fiocruz
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
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