Mixed infection by Histoplasma capsulatum isolates with different mating types in Brazilian AIDS-patients

Detalhes bibliográficos
Autor(a) principal: Damasceno, Lisandra Serra
Data de Publicação: 2019
Outros Autores: Vite-Garín, Tania, Ramírez, José Antonio, Rodríguez-Arellanes, Gabriela, Almeida, Marcos Abreu de, Muniz, Mauro de Medeiros, Mesquita, Jacó Ricarte Lima de, Leitão, Terezinha do Menino Jesus Silva, Taylor, Maria Lucia, Zancopé-Oliveira, Rosely Maria
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/32151
Resumo: Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Micologia. Setor Imunodiagnóstico. Rio de Janeiro, RJ, Brasil / Hospital São José de Doenças Infecciosas. Fortaleza, CE, Brasil.
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spelling Damasceno, Lisandra SerraVite-Garín, TaniaRamírez, José AntonioRodríguez-Arellanes, GabrielaAlmeida, Marcos Abreu deMuniz, Mauro de MedeirosMesquita, Jacó Ricarte Lima deLeitão, Terezinha do Menino Jesus SilvaTaylor, Maria LuciaZancopé-Oliveira, Rosely Maria2019-03-19T13:05:00Z2019-03-19T13:05:00Z2019DAMASCENO, Lisandra Serra et al. Mixed infection by Histoplasma capsulatum isolates with different mating types in Brazilian AIDS-patients. Revista do Instituto de Medicina Tropical de São Paulo, v. 61, p. 1-10, 2019.0036-4665https://www.arca.fiocruz.br/handle/icict/3215110.1590/s1678-99462019610081678-9946engUniversidade de São PauloMixed infection by Histoplasma capsulatum isolates with different mating types in Brazilian AIDS-patientsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Micologia. Setor Imunodiagnóstico. Rio de Janeiro, RJ, Brasil / Hospital São José de Doenças Infecciosas. Fortaleza, CE, Brasil.Universidad Nacional Autónoma de México. Facultad de Medicina. Departamento de Microbiología y Parasitología. Laboratorio de Inmunología de Hongos. Ciudad de México, MéxicoUniversidad Nacional Autónoma de México. Facultad de Medicina. Departamento de Microbiología y Parasitología. Laboratorio de Inmunología de Hongos. Ciudad de México, MéxicoUniversidad Nacional Autónoma de México. Facultad de Medicina. Departamento de Microbiología y Parasitología. Laboratorio de Inmunología de Hongos. Ciudad de México, MéxicoFundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Micologia. Setor Imunodiagnóstico. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Micologia. Setor Imunodiagnóstico. Rio de Janeiro, RJ, Brasil.Hospital São José de Doenças Infecciosas. Fortaleza, CE, Brasil.Hospital São José de Doenças Infecciosas. Fortaleza, CE, Brasil / Universidade Federal do Ceará. Faculdade de Medicina. Departamento de Saúde Comunitária. Fortaleza, CE, Brasil.Universidad Nacional Autónoma de México. Facultad de Medicina. Departamento de Microbiología y Parasitología. Laboratorio de Inmunología de Hongos. Ciudad de México, MéxicoFundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Micologia. Setor Imunodiagnóstico. Rio de Janeiro, RJ, Brasil.Mixed infection by Histoplasma capsulatum isolates with different mating types, in AIDS‑patients are described in this study. Morphological, mating type-specific PCR assay and multilocus sequencing type analysis of H. capsulatum isolates recovered from two Brazilian AIDS‑patients were performed. Five H. capsulatum isolates were recovered at different times from the two patients. Three isolates were obtained from bone marrow (day 1 – CE0411) and buffy coat cultures (day 1 – CE0311; day 2 – CE0511) of patient 1, and two isolates were isolated from buffy coat cultures (day 3 – CE2813; day 12 – CE2513) of patient 2. The mycelial colonies depicted different textures and pigmentation features. Dimorphic conversion to the yeast-phase in ML-Gema medium was achieved in all isolates. MAT1-1 idiomorph was identified in CE0311, CE0411 and CE2813 isolates; MAT1-2 idiomorph was found in CE0511 and CE2513 isolates. These H. capsulatum isolates were grouped within LAm A clade, highlighting that CE0311 and CE0411 isolates formed a subgroup supported by a high bootstrap value. The CE0511, CE2513, and CE2813 isolates clustered together with a Brazilian H151 isolate. This research reports mixed infections caused by H. capsulatum isolates with different mating types in Brazilian AIDS‑patients for the first time in the literature.Mixed infectionHistoplasma capsulatumMating typesMultilocus sequence typingHistoplasmosisHIV coinfectionsinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83104https://www.arca.fiocruz.br/bitstream/icict/32151/1/license.txt79178e5f2a0eb066867a274556814938MD51ORIGINALve_Damasceno_Lisandra_etal_INI_2019.pdfve_Damasceno_Lisandra_etal_INI_2019.pdfapplication/pdf1537506https://www.arca.fiocruz.br/bitstream/icict/32151/2/ve_Damasceno_Lisandra_etal_INI_2019.pdfe77ded8703ec63761e57cd1521ce749dMD52TEXTve_Damasceno_Lisandra_etal_INI_2019.pdf.txtve_Damasceno_Lisandra_etal_INI_2019.pdf.txtExtracted 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dc.title.pt_BR.fl_str_mv Mixed infection by Histoplasma capsulatum isolates with different mating types in Brazilian AIDS-patients
title Mixed infection by Histoplasma capsulatum isolates with different mating types in Brazilian AIDS-patients
spellingShingle Mixed infection by Histoplasma capsulatum isolates with different mating types in Brazilian AIDS-patients
Damasceno, Lisandra Serra
Mixed infection
Histoplasma capsulatum
Mating types
Multilocus sequence typing
Histoplasmosis
HIV coinfections
title_short Mixed infection by Histoplasma capsulatum isolates with different mating types in Brazilian AIDS-patients
title_full Mixed infection by Histoplasma capsulatum isolates with different mating types in Brazilian AIDS-patients
title_fullStr Mixed infection by Histoplasma capsulatum isolates with different mating types in Brazilian AIDS-patients
title_full_unstemmed Mixed infection by Histoplasma capsulatum isolates with different mating types in Brazilian AIDS-patients
title_sort Mixed infection by Histoplasma capsulatum isolates with different mating types in Brazilian AIDS-patients
author Damasceno, Lisandra Serra
author_facet Damasceno, Lisandra Serra
Vite-Garín, Tania
Ramírez, José Antonio
Rodríguez-Arellanes, Gabriela
Almeida, Marcos Abreu de
Muniz, Mauro de Medeiros
Mesquita, Jacó Ricarte Lima de
Leitão, Terezinha do Menino Jesus Silva
Taylor, Maria Lucia
Zancopé-Oliveira, Rosely Maria
author_role author
author2 Vite-Garín, Tania
Ramírez, José Antonio
Rodríguez-Arellanes, Gabriela
Almeida, Marcos Abreu de
Muniz, Mauro de Medeiros
Mesquita, Jacó Ricarte Lima de
Leitão, Terezinha do Menino Jesus Silva
Taylor, Maria Lucia
Zancopé-Oliveira, Rosely Maria
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Damasceno, Lisandra Serra
Vite-Garín, Tania
Ramírez, José Antonio
Rodríguez-Arellanes, Gabriela
Almeida, Marcos Abreu de
Muniz, Mauro de Medeiros
Mesquita, Jacó Ricarte Lima de
Leitão, Terezinha do Menino Jesus Silva
Taylor, Maria Lucia
Zancopé-Oliveira, Rosely Maria
dc.subject.en.pt_BR.fl_str_mv Mixed infection
Histoplasma capsulatum
Mating types
Multilocus sequence typing
Histoplasmosis
HIV coinfections
topic Mixed infection
Histoplasma capsulatum
Mating types
Multilocus sequence typing
Histoplasmosis
HIV coinfections
description Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Micologia. Setor Imunodiagnóstico. Rio de Janeiro, RJ, Brasil / Hospital São José de Doenças Infecciosas. Fortaleza, CE, Brasil.
publishDate 2019
dc.date.accessioned.fl_str_mv 2019-03-19T13:05:00Z
dc.date.available.fl_str_mv 2019-03-19T13:05:00Z
dc.date.issued.fl_str_mv 2019
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv DAMASCENO, Lisandra Serra et al. Mixed infection by Histoplasma capsulatum isolates with different mating types in Brazilian AIDS-patients. Revista do Instituto de Medicina Tropical de São Paulo, v. 61, p. 1-10, 2019.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/32151
dc.identifier.issn.pt_BR.fl_str_mv 0036-4665
dc.identifier.doi.none.fl_str_mv 10.1590/s1678-9946201961008
dc.identifier.eissn.none.fl_str_mv 1678-9946
identifier_str_mv DAMASCENO, Lisandra Serra et al. Mixed infection by Histoplasma capsulatum isolates with different mating types in Brazilian AIDS-patients. Revista do Instituto de Medicina Tropical de São Paulo, v. 61, p. 1-10, 2019.
0036-4665
10.1590/s1678-9946201961008
1678-9946
url https://www.arca.fiocruz.br/handle/icict/32151
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Universidade de São Paulo
publisher.none.fl_str_mv Universidade de São Paulo
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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https://www.arca.fiocruz.br/bitstream/icict/32151/2/ve_Damasceno_Lisandra_etal_INI_2019.pdf
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