The immunobiology of Leishmania braziliensis infection

Detalhes bibliográficos
Autor(a) principal: Oliveira, Camila Indiani de
Data de Publicação: 2012
Outros Autores: Brodskyn, Claudia Ida
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/7258
Resumo: Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil / Instituto de Investigação em Imunologia. Salvador, BA, Brasil
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spelling Oliveira, Camila Indiani deBrodskyn, Claudia Ida2013-11-25T16:10:18Z2013-11-25T16:10:18Z2012OLIVEIRA, C. I.; BRODSKYN, C. I. The immunobiology of Leishmania braziliensis infection. Frontiers Immunology, v. 3, p.145-153, 2012.1664-3224https://www.arca.fiocruz.br/handle/icict/725810.3389/fimmu.2012.00145engNational Institute of Allergy and Infectious Diseases,USAThe immunobiology of Leishmania braziliensis infectioninfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil / Instituto de Investigação em Imunologia. Salvador, BA, BrasilFundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil / Instituto de Investigação em Imunologia. Salvador, BA, BrasilLeishmaniasesareagroupofdiseasescausedbyprotozoaofthegenusLeishmaniathataffectmillionsofpeopleworldwide.ThesediseasesarecausedbydistinctLeishmaniaspecies,ofwhichL.braziliensis,aNewWorldrepresentativeoftheLeishmaniagenus,hasbeentheleaststudied.AlthoughleishmaniasiscausedbyL.braziliensisinducesarangeofclinicalmanifestationsrangingfrommildlocalizedlesionstoseveremucosalinvolvement,fewstudieshavefocusedonelucidatingtheimmunemechanismsbehindthispathology.Inthisreview,wefocusontheimmunobiologyofL.braziliensisinfection,emphasizingtheinnateandadaptiveimmuneresponsesandtakingintoconsiderationbothstudiesperformedinendemicareasandexperimentalmodelsofinfection.Additionally,weaddressrecentfindingsregardingtheroleofsandflysalivaindiseaseimmunopathogenesisandvaccinedevelopment.Leishmania braziliensisInnate immunityHuman adaptive immunologyAnimal modelsinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINALOliveira Camila I The immunobiology....pdfOliveira Camila I The immunobiology....pdfapplication/pdf289751https://www.arca.fiocruz.br/bitstream/icict/7258/1/Oliveira%20Camila%20I%20The%20immunobiology....pdf4b0b5be900a6c7d3bf32108e97f47cebMD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81914https://www.arca.fiocruz.br/bitstream/icict/7258/2/license.txt7d48279ffeed55da8dfe2f8e81f3b81fMD52TEXTOliveira Camila I The immunobiology....pdf.txtOliveira Camila I The immunobiology....pdf.txtExtracted texttext/plain65622https://www.arca.fiocruz.br/bitstream/icict/7258/5/Oliveira%20Camila%20I%20The%20immunobiology....pdf.txtb9f7f612f747886a40b4325dff42672fMD55THUMBNAILOliveira Camila I The immunobiology....pdf.jpgOliveira Camila I The immunobiology....pdf.jpgGenerated Thumbnailimage/jpeg1488https://www.arca.fiocruz.br/bitstream/icict/7258/4/Oliveira%20Camila%20I%20The%20immunobiology....pdf.jpgeca7ca5ecf840bfb33afd3860211552bMD54icict/72582023-03-15 14:32:55.232oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-03-15T17:32:55Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv The immunobiology of Leishmania braziliensis infection
title The immunobiology of Leishmania braziliensis infection
spellingShingle The immunobiology of Leishmania braziliensis infection
Oliveira, Camila Indiani de
Leishmania braziliensis
Innate immunity
Human adaptive immunology
Animal models
title_short The immunobiology of Leishmania braziliensis infection
title_full The immunobiology of Leishmania braziliensis infection
title_fullStr The immunobiology of Leishmania braziliensis infection
title_full_unstemmed The immunobiology of Leishmania braziliensis infection
title_sort The immunobiology of Leishmania braziliensis infection
author Oliveira, Camila Indiani de
author_facet Oliveira, Camila Indiani de
Brodskyn, Claudia Ida
author_role author
author2 Brodskyn, Claudia Ida
author2_role author
dc.contributor.author.fl_str_mv Oliveira, Camila Indiani de
Brodskyn, Claudia Ida
dc.subject.en.pt_BR.fl_str_mv Leishmania braziliensis
Innate immunity
Human adaptive immunology
Animal models
topic Leishmania braziliensis
Innate immunity
Human adaptive immunology
Animal models
description Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil / Instituto de Investigação em Imunologia. Salvador, BA, Brasil
publishDate 2012
dc.date.issued.fl_str_mv 2012
dc.date.accessioned.fl_str_mv 2013-11-25T16:10:18Z
dc.date.available.fl_str_mv 2013-11-25T16:10:18Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv OLIVEIRA, C. I.; BRODSKYN, C. I. The immunobiology of Leishmania braziliensis infection. Frontiers Immunology, v. 3, p.145-153, 2012.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/7258
dc.identifier.issn.none.fl_str_mv 1664-3224
dc.identifier.doi.none.fl_str_mv 10.3389/fimmu.2012.00145
identifier_str_mv OLIVEIRA, C. I.; BRODSKYN, C. I. The immunobiology of Leishmania braziliensis infection. Frontiers Immunology, v. 3, p.145-153, 2012.
1664-3224
10.3389/fimmu.2012.00145
url https://www.arca.fiocruz.br/handle/icict/7258
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv National Institute of Allergy and Infectious Diseases,USA
publisher.none.fl_str_mv National Institute of Allergy and Infectious Diseases,USA
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
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instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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