SARS-CoV-2 variant of concern P.1 (Gamma) infection in young and middle-aged patients admitted to the intensive care units of a single hospital in Salvador, northeast Brazil, February 2021 (Preprint)

Detalhes bibliográficos
Autor(a) principal: Nonaka, Carolina Kymie Vasques
Data de Publicação: 2021
Outros Autores: Gräf, Tiago, Barcia, Camila Araújo de Lorenzo, Costa, Vanessa Ferreira, Oliveira, Janderson Lopes de, Passos, Rogério da Hora, Bastos, Iasmin Nogueira, Santana, Maria Clara Brito de, Santos, Ian Marinho, Sousa, Karoline Almeida Felix de, Weber, Thamires Gomes Lopes, Siqueira, Isadora Cristina de, Rocha, Clarissa Araújo Gurgel, Mendes, Ana Verena Almeida, Souza, Bruno Solano de Freitas
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/48692
Resumo: A Rede Genômica Fiocruz é formada por especialistas de todas as unidades da Fundação no país e de institutos parceiros que se empenham diariamente em gerar dados mais robustos sobre o comportamento do SARS-Cov-2 e contribuir para um melhor preparo do país no enfrentamento da pandemia em termos de diagnóstico mais precisos e vacinas eficazes. Saiba mais sobre a Rede Genômica Fiocruz em: http://www.genomahcov.fiocruz.br/
id CRUZ_63d4c3bdcd7d10d9ff15f20f8110aaa8
oai_identifier_str oai:www.arca.fiocruz.br:icict/48692
network_acronym_str CRUZ
network_name_str Repositório Institucional da FIOCRUZ (ARCA)
repository_id_str 2135
spelling Nonaka, Carolina Kymie VasquesGräf, TiagoBarcia, Camila Araújo de LorenzoCosta, Vanessa FerreiraOliveira, Janderson Lopes dePassos, Rogério da HoraBastos, Iasmin NogueiraSantana, Maria Clara Brito deSantos, Ian MarinhoSousa, Karoline Almeida Felix deWeber, Thamires Gomes LopesSiqueira, Isadora Cristina deRocha, Clarissa Araújo GurgelMendes, Ana Verena AlmeidaSouza, Bruno Solano de Freitas2021-08-20T18:26:32Z2021-08-20T18:26:32Z2021NONAKA, Carolina Kymie Vasques et al. SARS-CoV-2 variant of concern P.1 (Gamma) infection in young and middle-aged patients admitted to the intensive care units of a single hospital in Salvador, northeast Brazil, February 2021. International Journal of Infectious Diseases, p. 1-20, 2021.1201-9712https://www.arca.fiocruz.br/handle/icict/4869210.1016/j.ijid.2021.08.003A Rede Genômica Fiocruz é formada por especialistas de todas as unidades da Fundação no país e de institutos parceiros que se empenham diariamente em gerar dados mais robustos sobre o comportamento do SARS-Cov-2 e contribuir para um melhor preparo do país no enfrentamento da pandemia em termos de diagnóstico mais precisos e vacinas eficazes. Saiba mais sobre a Rede Genômica Fiocruz em: http://www.genomahcov.fiocruz.br/National Committee for Ethics on Research (CONEP; CAAE: 29496920.8.0000.5262, 46821621.5.0000.0048 and 3.980.128 /2020).São Rafael Hospital. Center for Biotechnology and Cell Therapy. Salvador, BA, Brazil / D'Or Institute for Research and Education (IDOR). Salvador, BA, Brazil.Oswaldo Cruz Foundation. Gonçalo Moniz Institute. Salvador, BA, Brazil.São Rafael Hospital. Department of Infectology. Salvador, BA, Brazil.São Rafael Hospital. Intensive Care Unit. Salvador, BA, Brazil.São Rafael Hospital. Intensive Care Unit. Salvador, BA, Brazil.São Rafael Hospital. Intensive Care Unit. Salvador, BA, Brazil.Oswaldo Cruz Foundation. Gonçalo Moniz Institute. Salvador, BA, Brazil.Oswaldo Cruz Foundation. Gonçalo Moniz Institute. Salvador, BA, Brazil.São Rafael Hospital. Center for Biotechnology and Cell Therapy. Salvador, BA, Brazil / Oswaldo Cruz Foundation. Gonçalo Moniz Institute. Salvador, BA, Brazil.Oswaldo Cruz Foundation. Gonçalo Moniz Institute. Salvador, BA, Brazil.São Rafael Hospital. Clinical Laboratory. Salvador, BA, Brazil.Oswaldo Cruz Foundation. Gonçalo Moniz Institute. Salvador, BA, Brazil.São Rafael Hospital. Center for Biotechnology and Cell Therapy. Salvador, BA, Brazil / Oswaldo Cruz Foundation. Gonçalo Moniz Institute. Salvador, BA, Brazil.São Rafael Hospital. Department of Infectology. Salvador, BA, Brazil.São Rafael Hospital. Center for Biotechnology and Cell Therapy. Salvador, BA, Brazil / Oswaldo Cruz Foundation. Gonçalo Moniz Institute. Salvador, BA, Brazil.To evaluate changes in COVID-19 patients' characteristics occurring after the emergence of the SARS-CoV-2 variant of concern (VOC) P.1 (Gamma) by comparing the clinical, demographic and laboratory profile of patients hospitalized during the first (May-July 2020) and second (December 2020 - February 2021) pandemic waves. Methods: Data was collected from records of COVID-19 patients (n=4164) admitted to a single hospital in Salvador, Northeast Brazil. SARS-CoV-2 genome sequencing was performed in nasopharyngeal swab samples from 12 patients with age < 60 years-old admitted to the intensive care units (ICU) in February 2021. Results: From June 2020 to February 2021, the median age of patients admitted in the ICU decreased from 66 to 58 years (p<0.05), accompanied by an increased proportion of patients without comorbidities (15.32% vs 32.20%, p<0.0001). A significant reduction in the Ct values of SARS-CoV-2 RT-PCR tests was observed in the second wave (p<0.0001). Sequencing analysis detected lineage Gamma in all 12 ICU patients sampled in February 2021. Conclusion: Our results demonstrated an increased proportion of younger adults without comorbidities with severe disease during the second COVID-19 wave, shortly after the confirmation of local Gamma circulation.engElsevierhttps://www.arca.fiocruz.br/handle/icict/50679COVID-19SARS-CoV-2Unidades de Terapia IntensivaPandemiaRede Genômica FiocruzGENOMAHCOVCOVID-19SARS-CoV-2Intensive Care UnitsPandemicSARS-CoV-2 variant of concern P.1 (Gamma) infection in young and middle-aged patients admitted to the intensive care units of a single hospital in Salvador, northeast Brazil, February 2021 (Preprint)info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83097https://www.arca.fiocruz.br/bitstream/icict/48692/1/license.txt36b51ef91c52b5338d9d29ba0cc807bcMD51ORIGINALNonaka, Carolina Kymie Vasques Sars-Cov-2 variant....pdfNonaka, Carolina Kymie Vasques Sars-Cov-2 variant....pdfapplication/pdf792947https://www.arca.fiocruz.br/bitstream/icict/48692/2/Nonaka%2c%20Carolina%20Kymie%20Vasques%20Sars-Cov-2%20variant....pdf4f3c4e597457b81065f5125c50516f61MD52_AUTORIZACAO_DEPOSITO_ARCA_REDE_GENOMICA.pdf_AUTORIZACAO_DEPOSITO_ARCA_REDE_GENOMICA.pdfapplication/pdf134844https://www.arca.fiocruz.br/bitstream/icict/48692/4/_AUTORIZACAO_DEPOSITO_ARCA_REDE_GENOMICA.pdf28ef5cd96257018f624857e2ce8ab529MD54TEXTNonaka, Carolina Kymie Vasques Sars-Cov-2 variant....pdf.txtNonaka, Carolina Kymie Vasques Sars-Cov-2 variant....pdf.txtExtracted texttext/plain29461https://www.arca.fiocruz.br/bitstream/icict/48692/3/Nonaka%2c%20Carolina%20Kymie%20Vasques%20Sars-Cov-2%20variant....pdf.txtafd6efa97500c462daa316e1d9b378c3MD53icict/486922022-04-27 14:49:04.627oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352022-04-27T17:49:04Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv SARS-CoV-2 variant of concern P.1 (Gamma) infection in young and middle-aged patients admitted to the intensive care units of a single hospital in Salvador, northeast Brazil, February 2021 (Preprint)
title SARS-CoV-2 variant of concern P.1 (Gamma) infection in young and middle-aged patients admitted to the intensive care units of a single hospital in Salvador, northeast Brazil, February 2021 (Preprint)
spellingShingle SARS-CoV-2 variant of concern P.1 (Gamma) infection in young and middle-aged patients admitted to the intensive care units of a single hospital in Salvador, northeast Brazil, February 2021 (Preprint)
Nonaka, Carolina Kymie Vasques
COVID-19
SARS-CoV-2
Unidades de Terapia Intensiva
Pandemia
Rede Genômica Fiocruz
GENOMAHCOV
COVID-19
SARS-CoV-2
Intensive Care Units
Pandemic
title_short SARS-CoV-2 variant of concern P.1 (Gamma) infection in young and middle-aged patients admitted to the intensive care units of a single hospital in Salvador, northeast Brazil, February 2021 (Preprint)
title_full SARS-CoV-2 variant of concern P.1 (Gamma) infection in young and middle-aged patients admitted to the intensive care units of a single hospital in Salvador, northeast Brazil, February 2021 (Preprint)
title_fullStr SARS-CoV-2 variant of concern P.1 (Gamma) infection in young and middle-aged patients admitted to the intensive care units of a single hospital in Salvador, northeast Brazil, February 2021 (Preprint)
title_full_unstemmed SARS-CoV-2 variant of concern P.1 (Gamma) infection in young and middle-aged patients admitted to the intensive care units of a single hospital in Salvador, northeast Brazil, February 2021 (Preprint)
title_sort SARS-CoV-2 variant of concern P.1 (Gamma) infection in young and middle-aged patients admitted to the intensive care units of a single hospital in Salvador, northeast Brazil, February 2021 (Preprint)
author Nonaka, Carolina Kymie Vasques
author_facet Nonaka, Carolina Kymie Vasques
Gräf, Tiago
Barcia, Camila Araújo de Lorenzo
Costa, Vanessa Ferreira
Oliveira, Janderson Lopes de
Passos, Rogério da Hora
Bastos, Iasmin Nogueira
Santana, Maria Clara Brito de
Santos, Ian Marinho
Sousa, Karoline Almeida Felix de
Weber, Thamires Gomes Lopes
Siqueira, Isadora Cristina de
Rocha, Clarissa Araújo Gurgel
Mendes, Ana Verena Almeida
Souza, Bruno Solano de Freitas
author_role author
author2 Gräf, Tiago
Barcia, Camila Araújo de Lorenzo
Costa, Vanessa Ferreira
Oliveira, Janderson Lopes de
Passos, Rogério da Hora
Bastos, Iasmin Nogueira
Santana, Maria Clara Brito de
Santos, Ian Marinho
Sousa, Karoline Almeida Felix de
Weber, Thamires Gomes Lopes
Siqueira, Isadora Cristina de
Rocha, Clarissa Araújo Gurgel
Mendes, Ana Verena Almeida
Souza, Bruno Solano de Freitas
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Nonaka, Carolina Kymie Vasques
Gräf, Tiago
Barcia, Camila Araújo de Lorenzo
Costa, Vanessa Ferreira
Oliveira, Janderson Lopes de
Passos, Rogério da Hora
Bastos, Iasmin Nogueira
Santana, Maria Clara Brito de
Santos, Ian Marinho
Sousa, Karoline Almeida Felix de
Weber, Thamires Gomes Lopes
Siqueira, Isadora Cristina de
Rocha, Clarissa Araújo Gurgel
Mendes, Ana Verena Almeida
Souza, Bruno Solano de Freitas
dc.subject.other.pt_BR.fl_str_mv COVID-19
SARS-CoV-2
Unidades de Terapia Intensiva
Pandemia
Rede Genômica Fiocruz
GENOMAHCOV
topic COVID-19
SARS-CoV-2
Unidades de Terapia Intensiva
Pandemia
Rede Genômica Fiocruz
GENOMAHCOV
COVID-19
SARS-CoV-2
Intensive Care Units
Pandemic
dc.subject.en.pt_BR.fl_str_mv COVID-19
SARS-CoV-2
Intensive Care Units
Pandemic
description A Rede Genômica Fiocruz é formada por especialistas de todas as unidades da Fundação no país e de institutos parceiros que se empenham diariamente em gerar dados mais robustos sobre o comportamento do SARS-Cov-2 e contribuir para um melhor preparo do país no enfrentamento da pandemia em termos de diagnóstico mais precisos e vacinas eficazes. Saiba mais sobre a Rede Genômica Fiocruz em: http://www.genomahcov.fiocruz.br/
publishDate 2021
dc.date.accessioned.fl_str_mv 2021-08-20T18:26:32Z
dc.date.available.fl_str_mv 2021-08-20T18:26:32Z
dc.date.issued.fl_str_mv 2021
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv NONAKA, Carolina Kymie Vasques et al. SARS-CoV-2 variant of concern P.1 (Gamma) infection in young and middle-aged patients admitted to the intensive care units of a single hospital in Salvador, northeast Brazil, February 2021. International Journal of Infectious Diseases, p. 1-20, 2021.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/48692
dc.identifier.issn.pt_BR.fl_str_mv 1201-9712
dc.identifier.doi.pt_BR.fl_str_mv 10.1016/j.ijid.2021.08.003
identifier_str_mv NONAKA, Carolina Kymie Vasques et al. SARS-CoV-2 variant of concern P.1 (Gamma) infection in young and middle-aged patients admitted to the intensive care units of a single hospital in Salvador, northeast Brazil, February 2021. International Journal of Infectious Diseases, p. 1-20, 2021.
1201-9712
10.1016/j.ijid.2021.08.003
url https://www.arca.fiocruz.br/handle/icict/48692
dc.language.iso.fl_str_mv eng
language eng
dc.relation.hasversion.pt_BR.fl_str_mv https://www.arca.fiocruz.br/handle/icict/50679
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/48692/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/48692/2/Nonaka%2c%20Carolina%20Kymie%20Vasques%20Sars-Cov-2%20variant....pdf
https://www.arca.fiocruz.br/bitstream/icict/48692/4/_AUTORIZACAO_DEPOSITO_ARCA_REDE_GENOMICA.pdf
https://www.arca.fiocruz.br/bitstream/icict/48692/3/Nonaka%2c%20Carolina%20Kymie%20Vasques%20Sars-Cov-2%20variant....pdf.txt
bitstream.checksum.fl_str_mv 36b51ef91c52b5338d9d29ba0cc807bc
4f3c4e597457b81065f5125c50516f61
28ef5cd96257018f624857e2ce8ab529
afd6efa97500c462daa316e1d9b378c3
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
MD5
MD5
repository.name.fl_str_mv Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)
repository.mail.fl_str_mv repositorio.arca@fiocruz.br
_version_ 1798325066130259968

Registros relacionados