Genetic Diversity in Natural Populations of New World Leishmania

Detalhes bibliográficos
Autor(a) principal: Cupolillo, Elisa
Data de Publicação: 1998
Outros Autores: Momen, Hooman, Grimaldi Jr., Gabriel
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/43946
Resumo: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Imunologia. Laboratório de Leishmaniose. Rio de Janeiro, RJ, Brasil.
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spelling Cupolillo, ElisaMomen, HoomanGrimaldi Jr., Gabriel2020-10-12T18:20:13Z2020-10-12T18:20:13Z1998CUPOLILLO, Elisa; MOMEN, Hooman; GRIMALDI JR., Gabriel. Genetic Diversity in Natural Populations of New World Leishmania. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 94, n. 5, p. 663-668, Sept./Oct. 1998.0074-0276https://www.arca.fiocruz.br/handle/icict/4394610.1590/S0074-027619980005000181678-8060engFundação Oswaldo Cruz. Instituto Oswaldo Cruz.LeishmanioseLeishmania do Novo MundoEpidemiologiaMolecular caracterizaçãoNew World LeishmaniaLeishmaniasisEpidemiologyMolecular characterizationGenetic Diversity in Natural Populations of New World Leishmaniainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Imunologia. Laboratório de Leishmaniose. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Bioquímica e Biologia Molecular. Laboratório de Sistemática Bioquímica. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Imunologia. Laboratório de Leishmaniose. Rio de Janeiro, RJ, Brasil.Our results have shown the wide diversity of parasites within New World Leishmania. Biochemical and molecular characterization of species within the genus has revealed that much of the population heterogeneity has a genetic basis. The source of genetic diversity among Leishmania appears to arise from predominantly asexual, clonal reproduction, although occasional bouts of sexual reproduction can not be ruled out. Genetic variation is extensive with some clones widely distributed and others seemingly unique and localized to a particular endemic focus. Epidemiological studies of leishmaniasis has been directed to the ecology and dynamics of transmission of Leishmania species/variants, particularly in localized areas. Future research using molecular techniques should aim to identify and follow Leishmania types in nature and correlate genetic typing with important clinical characteristics such as virulence, pathogenicity, drug resistance and antigenic variation. 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dc.title.pt_BR.fl_str_mv Genetic Diversity in Natural Populations of New World Leishmania
title Genetic Diversity in Natural Populations of New World Leishmania
spellingShingle Genetic Diversity in Natural Populations of New World Leishmania
Cupolillo, Elisa
Leishmaniose
Leishmania do Novo Mundo
Epidemiologia
Molecular caracterização
New World Leishmania
Leishmaniasis
Epidemiology
Molecular characterization
title_short Genetic Diversity in Natural Populations of New World Leishmania
title_full Genetic Diversity in Natural Populations of New World Leishmania
title_fullStr Genetic Diversity in Natural Populations of New World Leishmania
title_full_unstemmed Genetic Diversity in Natural Populations of New World Leishmania
title_sort Genetic Diversity in Natural Populations of New World Leishmania
author Cupolillo, Elisa
author_facet Cupolillo, Elisa
Momen, Hooman
Grimaldi Jr., Gabriel
author_role author
author2 Momen, Hooman
Grimaldi Jr., Gabriel
author2_role author
author
dc.contributor.author.fl_str_mv Cupolillo, Elisa
Momen, Hooman
Grimaldi Jr., Gabriel
dc.subject.other.pt_BR.fl_str_mv Leishmaniose
Leishmania do Novo Mundo
Epidemiologia
Molecular caracterização
topic Leishmaniose
Leishmania do Novo Mundo
Epidemiologia
Molecular caracterização
New World Leishmania
Leishmaniasis
Epidemiology
Molecular characterization
dc.subject.en.pt_BR.fl_str_mv New World Leishmania
Leishmaniasis
Epidemiology
Molecular characterization
description Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Imunologia. Laboratório de Leishmaniose. Rio de Janeiro, RJ, Brasil.
publishDate 1998
dc.date.issued.fl_str_mv 1998
dc.date.accessioned.fl_str_mv 2020-10-12T18:20:13Z
dc.date.available.fl_str_mv 2020-10-12T18:20:13Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.citation.fl_str_mv CUPOLILLO, Elisa; MOMEN, Hooman; GRIMALDI JR., Gabriel. Genetic Diversity in Natural Populations of New World Leishmania. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 94, n. 5, p. 663-668, Sept./Oct. 1998.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/43946
dc.identifier.issn.pt_BR.fl_str_mv 0074-0276
dc.identifier.doi.none.fl_str_mv 10.1590/S0074-02761998000500018
dc.identifier.eissn.none.fl_str_mv 1678-8060
identifier_str_mv CUPOLILLO, Elisa; MOMEN, Hooman; GRIMALDI JR., Gabriel. Genetic Diversity in Natural Populations of New World Leishmania. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 94, n. 5, p. 663-668, Sept./Oct. 1998.
0074-0276
10.1590/S0074-02761998000500018
1678-8060
url https://www.arca.fiocruz.br/handle/icict/43946
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto Oswaldo Cruz.
publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto Oswaldo Cruz.
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
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