The effect of Ageratum fastigiatum extract on Rhodnius nasutus, vector of Chagas disease

Detalhes bibliográficos
Autor(a) principal: Freitas, Bethânia Alves de Avelar
Data de Publicação: 2013
Outros Autores: Dias, João Victor Leite, Tibães, Gabrielle Guedes, Rocha, Camila Aguiar, Oliveira, Gustavo Henrique Bahia, Grael, Cristiane Fernanda Fuzer, Pires, Herton Helder Rocha
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/30087
Resumo: Universidade Federal dos Vales do Jequitinhonha e Mucuri. Laboratório de Imunologia. Diamantina, MG, Brazil
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spelling Freitas, Bethânia Alves de AvelarDias, João Victor LeiteTibães, Gabrielle GuedesRocha, Camila AguiarOliveira, Gustavo Henrique BahiaGrael, Cristiane Fernanda FuzerPires, Herton Helder Rocha2018-11-19T12:21:46Z2018-11-19T12:21:46Z2013FREITAS, Bethânia Alves de Avelar et al. The effect of Ageratum fastigiatum extract on Rhodnius nasutus, vector of Chagas disease. Rev. bras. farmacogn., v. 23, n. 2, p. 366-369, 2013.0102-695Xhttps://www.arca.fiocruz.br/handle/icict/3008710.1590/S0102-695X2012005000139engSociedade Brasileira de FarmacognosiaAgeratum fastigiatumatividades inseticidastriatomineosAgeratum fastigiatuminsecticidal activityTriatominaeThe effect of Ageratum fastigiatum extract on Rhodnius nasutus, vector of Chagas diseaseinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal dos Vales do Jequitinhonha e Mucuri. Laboratório de Imunologia. Diamantina, MG, BrazilUniversidade Federal dos Vales do Jequitinhonha e Mucuri. Laboratório de Doenças Parasitárias. Diamantina, MG, Brazil/Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Laboratório de Triatomíneos e Epidemiologia da Doença de Chagas. Belo Horizinte, MG, BrazilUniversidade Federal dos Vales do Jequitinhonha e Mucuri. Laboratório de Doenças Parasitárias. Diamantina, MG, BrazilUniversidade Federal dos Vales do Jequitinhonha e Mucuri. Laboratório de Doenças Parasitárias. Diamantina, MG, BrazilUniversidade Federal dos Vales do Jequitinhonha e Mucuri. Laboratório de Doenças Parasitárias. Diamantina, MG, BrazilUniversidade Federal dos Vales do Jequitinhonha e Mucuri. Laboratório de Fitoquímica. Diamantina, MG, BrazilUniversidade Federal dos Vales do Jequitinhonha e Mucuri. Laboratório de Doenças Parasitárias. Diamantina, MG, BrazilControl of Chagas disease is based on insecticide spraying in domiciles in order to exterminate triatomine populations. However, since the vectors differ in susceptibility to currently used insecticides, the screening of the toxic potential of Brazilian flora may identify new molecules lethal to triatomines. This study evaluated the toxicity of ethanolic extract of Ageratum fastigiatum (Gardner) R.M. King & H. Rob., Asteraceae, on Rhodnius nasutus, a known vector of Chagas disease. Ethanolic extracts of the aerial parts of A. fastigiatum were prepared at 25 and 50 mg/mL concentrations, and 5 µL was applied to fifth-instar nymphs of R. nasutus (n=30). Controls included nymphs that were treated with 5 µL ethanol (n=30) or left untreated (n=30). The percentage of dead insects in each group was observed at 24, 48, 72, 96 and 120 h after application. The extracts of A. fastigiatum showed a mortality rate of about 37% and 77% after 120 h, at concentrations of 25 and 50 mg/mL, respectively. In control groups, the mortality rate remained under 7%. The extract of A. fastigiatum contains a coumarin, a molecule with recognized toxicity in insects, and which may be responsible for killing the triatomines.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83082https://www.arca.fiocruz.br/bitstream/icict/30087/1/license.txt9193a7c197bc67acd023525e72a03240MD51ORIGINALThe effect of Ageratum fastigiatum extract.pdfThe effect of Ageratum fastigiatum extract.pdfapplication/pdf3000843https://www.arca.fiocruz.br/bitstream/icict/30087/2/The%20effect%20of%20Ageratum%20fastigiatum%20extract.pdfdafb8589d2f5f26f7a7e343250c365faMD52TEXTThe effect of Ageratum fastigiatum extract.pdf.txtThe effect of Ageratum fastigiatum extract.pdf.txtExtracted 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dc.title.pt_BR.fl_str_mv The effect of Ageratum fastigiatum extract on Rhodnius nasutus, vector of Chagas disease
title The effect of Ageratum fastigiatum extract on Rhodnius nasutus, vector of Chagas disease
spellingShingle The effect of Ageratum fastigiatum extract on Rhodnius nasutus, vector of Chagas disease
Freitas, Bethânia Alves de Avelar
Ageratum fastigiatum
atividades inseticidas
triatomineos
Ageratum fastigiatum
insecticidal activity
Triatominae
title_short The effect of Ageratum fastigiatum extract on Rhodnius nasutus, vector of Chagas disease
title_full The effect of Ageratum fastigiatum extract on Rhodnius nasutus, vector of Chagas disease
title_fullStr The effect of Ageratum fastigiatum extract on Rhodnius nasutus, vector of Chagas disease
title_full_unstemmed The effect of Ageratum fastigiatum extract on Rhodnius nasutus, vector of Chagas disease
title_sort The effect of Ageratum fastigiatum extract on Rhodnius nasutus, vector of Chagas disease
author Freitas, Bethânia Alves de Avelar
author_facet Freitas, Bethânia Alves de Avelar
Dias, João Victor Leite
Tibães, Gabrielle Guedes
Rocha, Camila Aguiar
Oliveira, Gustavo Henrique Bahia
Grael, Cristiane Fernanda Fuzer
Pires, Herton Helder Rocha
author_role author
author2 Dias, João Victor Leite
Tibães, Gabrielle Guedes
Rocha, Camila Aguiar
Oliveira, Gustavo Henrique Bahia
Grael, Cristiane Fernanda Fuzer
Pires, Herton Helder Rocha
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Freitas, Bethânia Alves de Avelar
Dias, João Victor Leite
Tibães, Gabrielle Guedes
Rocha, Camila Aguiar
Oliveira, Gustavo Henrique Bahia
Grael, Cristiane Fernanda Fuzer
Pires, Herton Helder Rocha
dc.subject.other.pt_BR.fl_str_mv Ageratum fastigiatum
atividades inseticidas
triatomineos
topic Ageratum fastigiatum
atividades inseticidas
triatomineos
Ageratum fastigiatum
insecticidal activity
Triatominae
dc.subject.en.pt_BR.fl_str_mv Ageratum fastigiatum
insecticidal activity
Triatominae
description Universidade Federal dos Vales do Jequitinhonha e Mucuri. Laboratório de Imunologia. Diamantina, MG, Brazil
publishDate 2013
dc.date.issued.fl_str_mv 2013
dc.date.accessioned.fl_str_mv 2018-11-19T12:21:46Z
dc.date.available.fl_str_mv 2018-11-19T12:21:46Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv FREITAS, Bethânia Alves de Avelar et al. The effect of Ageratum fastigiatum extract on Rhodnius nasutus, vector of Chagas disease. Rev. bras. farmacogn., v. 23, n. 2, p. 366-369, 2013.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/30087
dc.identifier.issn.pt_BR.fl_str_mv 0102-695X
dc.identifier.doi.none.fl_str_mv 10.1590/S0102-695X2012005000139
identifier_str_mv FREITAS, Bethânia Alves de Avelar et al. The effect of Ageratum fastigiatum extract on Rhodnius nasutus, vector of Chagas disease. Rev. bras. farmacogn., v. 23, n. 2, p. 366-369, 2013.
0102-695X
10.1590/S0102-695X2012005000139
url https://www.arca.fiocruz.br/handle/icict/30087
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Sociedade Brasileira de Farmacognosia
publisher.none.fl_str_mv Sociedade Brasileira de Farmacognosia
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
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instacron_str FIOCRUZ
institution FIOCRUZ
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