The effect of Ageratum fastigiatum extract on Rhodnius nasutus, vector of Chagas disease
Autor(a) principal: | |
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Data de Publicação: | 2013 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Revista Brasileira de Farmacognosia (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2013000200023 |
Resumo: | Control of Chagas disease is based on insecticide spraying in domiciles in order to exterminate triatomine populations. However, since the vectors differ in susceptibility to currently used insecticides, the screening of the toxic potential of Brazilian flora may identify new molecules lethal to triatomines. This study evaluated the toxicity of ethanolic extract of Ageratum fastigiatum (Gardner) R.M. King & H. Rob., Asteraceae, on Rhodnius nasutus, a known vector of Chagas disease. Ethanolic extracts of the aerial parts of A. fastigiatum were prepared at 25 and 50 mg/mL concentrations, and 5 µL was applied to fifth-instar nymphs of R. nasutus (n=30). Controls included nymphs that were treated with 5 µL ethanol (n=30) or left untreated (n=30). The percentage of dead insects in each group was observed at 24, 48, 72, 96 and 120 h after application. The extracts of A. fastigiatum showed a mortality rate of about 37% and 77% after 120 h, at concentrations of 25 and 50 mg/mL, respectively. In control groups, the mortality rate remained under 7%. The extract of A. fastigiatum contains a coumarin, a molecule with recognized toxicity in insects, and which may be responsible for killing the triatomines. |
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The effect of Ageratum fastigiatum extract on Rhodnius nasutus, vector of Chagas diseaseAgeratum fastigiatuminsecticidal activityTriatominaeControl of Chagas disease is based on insecticide spraying in domiciles in order to exterminate triatomine populations. However, since the vectors differ in susceptibility to currently used insecticides, the screening of the toxic potential of Brazilian flora may identify new molecules lethal to triatomines. This study evaluated the toxicity of ethanolic extract of Ageratum fastigiatum (Gardner) R.M. King & H. Rob., Asteraceae, on Rhodnius nasutus, a known vector of Chagas disease. Ethanolic extracts of the aerial parts of A. fastigiatum were prepared at 25 and 50 mg/mL concentrations, and 5 µL was applied to fifth-instar nymphs of R. nasutus (n=30). Controls included nymphs that were treated with 5 µL ethanol (n=30) or left untreated (n=30). The percentage of dead insects in each group was observed at 24, 48, 72, 96 and 120 h after application. The extracts of A. fastigiatum showed a mortality rate of about 37% and 77% after 120 h, at concentrations of 25 and 50 mg/mL, respectively. In control groups, the mortality rate remained under 7%. The extract of A. fastigiatum contains a coumarin, a molecule with recognized toxicity in insects, and which may be responsible for killing the triatomines.Sociedade Brasileira de Farmacognosia2013-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2013000200023Revista Brasileira de Farmacognosia v.23 n.2 2013reponame:Revista Brasileira de Farmacognosia (Online)instname:Sociedade Brasileira de Farmacognosia (SBFgnosia)instacron:SBFGNOSIA10.1590/S0102-695X2012005000139info:eu-repo/semantics/openAccessAvelar-Freitas,Bethânia A.Dias,João V. L.Tibães,Gabrielle G.Rocha,Camila A.Bahia-Oliveira,Gustavo H.Grael,Cristiane F. F.Pires,Herton H. R.eng2013-03-27T00:00:00Zoai:scielo:S0102-695X2013000200023Revistahttp://www.sbfgnosia.org.br/revista/https://old.scielo.br/oai/scielo-oai.phprbgnosia@ltf.ufpb.br1981-528X0102-695Xopendoar:2013-03-27T00:00Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia)false |
dc.title.none.fl_str_mv |
The effect of Ageratum fastigiatum extract on Rhodnius nasutus, vector of Chagas disease |
title |
The effect of Ageratum fastigiatum extract on Rhodnius nasutus, vector of Chagas disease |
spellingShingle |
The effect of Ageratum fastigiatum extract on Rhodnius nasutus, vector of Chagas disease Avelar-Freitas,Bethânia A. Ageratum fastigiatum insecticidal activity Triatominae |
title_short |
The effect of Ageratum fastigiatum extract on Rhodnius nasutus, vector of Chagas disease |
title_full |
The effect of Ageratum fastigiatum extract on Rhodnius nasutus, vector of Chagas disease |
title_fullStr |
The effect of Ageratum fastigiatum extract on Rhodnius nasutus, vector of Chagas disease |
title_full_unstemmed |
The effect of Ageratum fastigiatum extract on Rhodnius nasutus, vector of Chagas disease |
title_sort |
The effect of Ageratum fastigiatum extract on Rhodnius nasutus, vector of Chagas disease |
author |
Avelar-Freitas,Bethânia A. |
author_facet |
Avelar-Freitas,Bethânia A. Dias,João V. L. Tibães,Gabrielle G. Rocha,Camila A. Bahia-Oliveira,Gustavo H. Grael,Cristiane F. F. Pires,Herton H. R. |
author_role |
author |
author2 |
Dias,João V. L. Tibães,Gabrielle G. Rocha,Camila A. Bahia-Oliveira,Gustavo H. Grael,Cristiane F. F. Pires,Herton H. R. |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Avelar-Freitas,Bethânia A. Dias,João V. L. Tibães,Gabrielle G. Rocha,Camila A. Bahia-Oliveira,Gustavo H. Grael,Cristiane F. F. Pires,Herton H. R. |
dc.subject.por.fl_str_mv |
Ageratum fastigiatum insecticidal activity Triatominae |
topic |
Ageratum fastigiatum insecticidal activity Triatominae |
description |
Control of Chagas disease is based on insecticide spraying in domiciles in order to exterminate triatomine populations. However, since the vectors differ in susceptibility to currently used insecticides, the screening of the toxic potential of Brazilian flora may identify new molecules lethal to triatomines. This study evaluated the toxicity of ethanolic extract of Ageratum fastigiatum (Gardner) R.M. King & H. Rob., Asteraceae, on Rhodnius nasutus, a known vector of Chagas disease. Ethanolic extracts of the aerial parts of A. fastigiatum were prepared at 25 and 50 mg/mL concentrations, and 5 µL was applied to fifth-instar nymphs of R. nasutus (n=30). Controls included nymphs that were treated with 5 µL ethanol (n=30) or left untreated (n=30). The percentage of dead insects in each group was observed at 24, 48, 72, 96 and 120 h after application. The extracts of A. fastigiatum showed a mortality rate of about 37% and 77% after 120 h, at concentrations of 25 and 50 mg/mL, respectively. In control groups, the mortality rate remained under 7%. The extract of A. fastigiatum contains a coumarin, a molecule with recognized toxicity in insects, and which may be responsible for killing the triatomines. |
publishDate |
2013 |
dc.date.none.fl_str_mv |
2013-04-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2013000200023 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2013000200023 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0102-695X2012005000139 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Farmacognosia |
publisher.none.fl_str_mv |
Sociedade Brasileira de Farmacognosia |
dc.source.none.fl_str_mv |
Revista Brasileira de Farmacognosia v.23 n.2 2013 reponame:Revista Brasileira de Farmacognosia (Online) instname:Sociedade Brasileira de Farmacognosia (SBFgnosia) instacron:SBFGNOSIA |
instname_str |
Sociedade Brasileira de Farmacognosia (SBFgnosia) |
instacron_str |
SBFGNOSIA |
institution |
SBFGNOSIA |
reponame_str |
Revista Brasileira de Farmacognosia (Online) |
collection |
Revista Brasileira de Farmacognosia (Online) |
repository.name.fl_str_mv |
Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia) |
repository.mail.fl_str_mv |
rbgnosia@ltf.ufpb.br |
_version_ |
1752122468309401600 |