Exposure to and infection by Leishmania infantum among domestic dogs in an area of the Cerrado biome, Maranhao, Brazil

Detalhes bibliográficos
Autor(a) principal: Reis, Andrea Teles dos
Data de Publicação: 2023
Outros Autores: Silva, Carla Fernanda do Carmo, Rocha, Thaís Bastos, Coutinho, Danielle Jordany Barros, Costa, Andréa Pereira da, Costa, Francisco Borges, Souza, Fernando Almeida, Nogueira, Rita de Maria Seabra
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/58277
Resumo: Universidade do Estado do Maranhão. São Luis, MA, Brasil.
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spelling Reis, Andrea Teles dosSilva, Carla Fernanda do CarmoRocha, Thaís BastosCoutinho, Danielle Jordany BarrosCosta, Andréa Pereira daCosta, Francisco BorgesSouza, Fernando AlmeidaNogueira, Rita de Maria Seabra2023-05-10T12:39:09Z2023-05-10T12:39:09Z2023REIS, Andrea Teles dos et al. Exposure to and infection by Leishmania infantum among domestic dogs in an area of the Cerrado biome, Maranhao, Brasil. Veterinary Parasitology: Regional Studies and Reports, v.39, 100851, p. 1 - 6, 2023.2405-9390https://www.arca.fiocruz.br/handle/icict/5827710.1016/j.vprsr.2023.100851engElsevier B.V.Fatores de RiscoEpidemiologiaLeishmaniaLeishmaniaRisk factorsEpidemiologyLeishmaniaExposure to and infection by Leishmania infantum among domestic dogs in an area of the Cerrado biome, Maranhao, Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade do Estado do Maranhão. São Luis, MA, Brasil.Universidade do Estado do Maranhão. São Luis, MA, Brasil.Universidade do Estado do Maranhão. São Luis, MA, Brasil.Universidade do Estado do Maranhão. São Luis, MA, Brasil.Universidade do Estado do Maranhão. São Luis, MA, Brasil.Universidade do Estado do Maranhão. São Luis, MA, Brasil.Universidade do Estado do Maranhão. São Luis, MA, Brasil / Fundação oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunomodulação e Protozoologia. Rio de Janeiro, RJ, Brasil.Universidade do Estado do Maranhão. São Luis, MA, Brasil.Visceral Leishmaniasis is a serious public health problem and dogs are considered to be the main source of infection in urban areas. In Brazil, this disease is present in all regions, but with high concentration of cases in the Northeast, and the state of Maranh˜ ao is considered to be an endemic region. The aim of this study was to conduct an epidemiological, spatial, molecular and serological survey on Leishmania infantum among domestic dogs in the municipality of Belagua, ´ Maranhao. ˜ Blood samples were collected from dogs and questionnaires were applied to their owners to obtain epidemiological data and risk factors relating to this zoonosis in the region. The coordinates of the dogs’ homes were obtained to produce a disease risk map. Serological diagnoses were made using the indirect immunofluorescence reaction (IFAT) and the dual-path platform chromatographic immunoassay test (DPP®) (Bio-Manguinhos/FIOCRUZ, Brazil). A molecular investigation was undertaken using the polymerase chain reaction (PCR). Georeferencing was performed using the global positioning system (GPS) and cases of canine visceral leishmaniasis in the municipality were spatially represented and analyzed using QGIS version 3.16.6 (QGIS Development Team, 2021). A total of 205 blood samples were collected, of which 122 (59.51%) were seroreactive for L. infantum through IFAT, while the DPP test showed 84 reactive samples (40.97%). IFAT and DPP detected 16 positive animals simultaneously. One sample that was seroreactive through IFAT was also positive through PCR. In the clinical evaluation, it was observed that among the seropositive dogs, 112 (91.80%) were symptomatic and 10 (8.20%) were asymptomatic. In the spatial analysis, the Kernel density estimator enabled determination of the place at greatest risk of occurrence of the disease. The areas with the highest concentrations of cases were in districts with large quantities of precarious housing and lack of basic sanitation. This was the first report on the occurrence of L. infantum among dogs in the municipality of Belagua. ´ The results show that canine visceral leishmaniasis is well dispersed in this municipality, thus putting at risk the human population.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/58277/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALAndreaTelesReis_etal_IOC_2023.pdfAndreaTelesReis_etal_IOC_2023.pdfapplication/pdf1842875https://www.arca.fiocruz.br/bitstream/icict/58277/2/AndreaTelesReis_etal_IOC_2023.pdf2cda108a36dff9a099469349627bbe09MD52icict/582772023-09-04 10:53:50.802oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-09-04T13:53:50Repositório Institucional da FIOCRUZ (ARCA) - 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dc.title.en_US.fl_str_mv Exposure to and infection by Leishmania infantum among domestic dogs in an area of the Cerrado biome, Maranhao, Brazil
title Exposure to and infection by Leishmania infantum among domestic dogs in an area of the Cerrado biome, Maranhao, Brazil
spellingShingle Exposure to and infection by Leishmania infantum among domestic dogs in an area of the Cerrado biome, Maranhao, Brazil
Reis, Andrea Teles dos
Fatores de Risco
Epidemiologia
Leishmania
Leishmania
Risk factors
Epidemiology
Leishmania
title_short Exposure to and infection by Leishmania infantum among domestic dogs in an area of the Cerrado biome, Maranhao, Brazil
title_full Exposure to and infection by Leishmania infantum among domestic dogs in an area of the Cerrado biome, Maranhao, Brazil
title_fullStr Exposure to and infection by Leishmania infantum among domestic dogs in an area of the Cerrado biome, Maranhao, Brazil
title_full_unstemmed Exposure to and infection by Leishmania infantum among domestic dogs in an area of the Cerrado biome, Maranhao, Brazil
title_sort Exposure to and infection by Leishmania infantum among domestic dogs in an area of the Cerrado biome, Maranhao, Brazil
author Reis, Andrea Teles dos
author_facet Reis, Andrea Teles dos
Silva, Carla Fernanda do Carmo
Rocha, Thaís Bastos
Coutinho, Danielle Jordany Barros
Costa, Andréa Pereira da
Costa, Francisco Borges
Souza, Fernando Almeida
Nogueira, Rita de Maria Seabra
author_role author
author2 Silva, Carla Fernanda do Carmo
Rocha, Thaís Bastos
Coutinho, Danielle Jordany Barros
Costa, Andréa Pereira da
Costa, Francisco Borges
Souza, Fernando Almeida
Nogueira, Rita de Maria Seabra
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Reis, Andrea Teles dos
Silva, Carla Fernanda do Carmo
Rocha, Thaís Bastos
Coutinho, Danielle Jordany Barros
Costa, Andréa Pereira da
Costa, Francisco Borges
Souza, Fernando Almeida
Nogueira, Rita de Maria Seabra
dc.subject.other.en_US.fl_str_mv Fatores de Risco
Epidemiologia
Leishmania
topic Fatores de Risco
Epidemiologia
Leishmania
Leishmania
Risk factors
Epidemiology
Leishmania
dc.subject.en.en_US.fl_str_mv Leishmania
Risk factors
Epidemiology
dc.subject.es.en_US.fl_str_mv Leishmania
description Universidade do Estado do Maranhão. São Luis, MA, Brasil.
publishDate 2023
dc.date.accessioned.fl_str_mv 2023-05-10T12:39:09Z
dc.date.available.fl_str_mv 2023-05-10T12:39:09Z
dc.date.issued.fl_str_mv 2023
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv REIS, Andrea Teles dos et al. Exposure to and infection by Leishmania infantum among domestic dogs in an area of the Cerrado biome, Maranhao, Brasil. Veterinary Parasitology: Regional Studies and Reports, v.39, 100851, p. 1 - 6, 2023.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/58277
dc.identifier.issn.en_US.fl_str_mv 2405-9390
dc.identifier.eissn.none.fl_str_mv 10.1016/j.vprsr.2023.100851
identifier_str_mv REIS, Andrea Teles dos et al. Exposure to and infection by Leishmania infantum among domestic dogs in an area of the Cerrado biome, Maranhao, Brasil. Veterinary Parasitology: Regional Studies and Reports, v.39, 100851, p. 1 - 6, 2023.
2405-9390
10.1016/j.vprsr.2023.100851
url https://www.arca.fiocruz.br/handle/icict/58277
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Elsevier B.V.
publisher.none.fl_str_mv Elsevier B.V.
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/58277/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/58277/2/AndreaTelesReis_etal_IOC_2023.pdf
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