Exposure to and infection by Leishmania infantum among domestic dogs in an area of the Cerrado biome, Maranhao, Brazil
Autor(a) principal: | |
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Data de Publicação: | 2023 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
Texto Completo: | https://www.arca.fiocruz.br/handle/icict/58277 |
Resumo: | Universidade do Estado do Maranhão. São Luis, MA, Brasil. |
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Reis, Andrea Teles dosSilva, Carla Fernanda do CarmoRocha, Thaís BastosCoutinho, Danielle Jordany BarrosCosta, Andréa Pereira daCosta, Francisco BorgesSouza, Fernando AlmeidaNogueira, Rita de Maria Seabra2023-05-10T12:39:09Z2023-05-10T12:39:09Z2023REIS, Andrea Teles dos et al. Exposure to and infection by Leishmania infantum among domestic dogs in an area of the Cerrado biome, Maranhao, Brasil. Veterinary Parasitology: Regional Studies and Reports, v.39, 100851, p. 1 - 6, 2023.2405-9390https://www.arca.fiocruz.br/handle/icict/5827710.1016/j.vprsr.2023.100851engElsevier B.V.Fatores de RiscoEpidemiologiaLeishmaniaLeishmaniaRisk factorsEpidemiologyLeishmaniaExposure to and infection by Leishmania infantum among domestic dogs in an area of the Cerrado biome, Maranhao, Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade do Estado do Maranhão. São Luis, MA, Brasil.Universidade do Estado do Maranhão. São Luis, MA, Brasil.Universidade do Estado do Maranhão. São Luis, MA, Brasil.Universidade do Estado do Maranhão. São Luis, MA, Brasil.Universidade do Estado do Maranhão. São Luis, MA, Brasil.Universidade do Estado do Maranhão. São Luis, MA, Brasil.Universidade do Estado do Maranhão. São Luis, MA, Brasil / Fundação oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunomodulação e Protozoologia. Rio de Janeiro, RJ, Brasil.Universidade do Estado do Maranhão. São Luis, MA, Brasil.Visceral Leishmaniasis is a serious public health problem and dogs are considered to be the main source of infection in urban areas. In Brazil, this disease is present in all regions, but with high concentration of cases in the Northeast, and the state of Maranh˜ ao is considered to be an endemic region. The aim of this study was to conduct an epidemiological, spatial, molecular and serological survey on Leishmania infantum among domestic dogs in the municipality of Belagua, ´ Maranhao. ˜ Blood samples were collected from dogs and questionnaires were applied to their owners to obtain epidemiological data and risk factors relating to this zoonosis in the region. The coordinates of the dogs’ homes were obtained to produce a disease risk map. Serological diagnoses were made using the indirect immunofluorescence reaction (IFAT) and the dual-path platform chromatographic immunoassay test (DPP®) (Bio-Manguinhos/FIOCRUZ, Brazil). A molecular investigation was undertaken using the polymerase chain reaction (PCR). Georeferencing was performed using the global positioning system (GPS) and cases of canine visceral leishmaniasis in the municipality were spatially represented and analyzed using QGIS version 3.16.6 (QGIS Development Team, 2021). A total of 205 blood samples were collected, of which 122 (59.51%) were seroreactive for L. infantum through IFAT, while the DPP test showed 84 reactive samples (40.97%). IFAT and DPP detected 16 positive animals simultaneously. One sample that was seroreactive through IFAT was also positive through PCR. In the clinical evaluation, it was observed that among the seropositive dogs, 112 (91.80%) were symptomatic and 10 (8.20%) were asymptomatic. In the spatial analysis, the Kernel density estimator enabled determination of the place at greatest risk of occurrence of the disease. The areas with the highest concentrations of cases were in districts with large quantities of precarious housing and lack of basic sanitation. This was the first report on the occurrence of L. infantum among dogs in the municipality of Belagua. ´ The results show that canine visceral leishmaniasis is well dispersed in this municipality, thus putting at risk the human population.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/58277/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALAndreaTelesReis_etal_IOC_2023.pdfAndreaTelesReis_etal_IOC_2023.pdfapplication/pdf1842875https://www.arca.fiocruz.br/bitstream/icict/58277/2/AndreaTelesReis_etal_IOC_2023.pdf2cda108a36dff9a099469349627bbe09MD52icict/582772023-09-04 10:53:50.802oai:www.arca.fiocruz.br:icict/58277Q0VTU8ODTyBOw4NPIEVYQ0xVU0lWQSBERSBESVJFSVRPUyBBVVRPUkFJUwoKQW8gYWNlaXRhciBvcyBURVJNT1MgZSBDT05EScOHw5VFUyBkZXN0YSBDRVNTw4NPLCBvIEFVVE9SIGUvb3UgVElUVUxBUiBkZSBkaXJlaXRvcwphdXRvcmFpcyBzb2JyZSBhIE9CUkEgZGUgcXVlIHRyYXRhIGVzdGUgZG9jdW1lbnRvOgoKKDEpIENFREUgZSBUUkFOU0ZFUkUsIHRvdGFsIGUgZ3JhdHVpdGFtZW50ZSwgw6AgRklPQ1JVWiAtIEZVTkRBw4fDg08gT1NXQUxETyBDUlVaLCBlbQpjYXLDoXRlciBwZXJtYW5lbnRlLCBpcnJldm9nw6F2ZWwgZSBOw4NPIEVYQ0xVU0lWTywgdG9kb3Mgb3MgZGlyZWl0b3MgcGF0cmltb25pYWlzIE7Dg08KQ09NRVJDSUFJUyBkZSB1dGlsaXphw6fDo28gZGEgT0JSQSBhcnTDrXN0aWNhIGUvb3UgY2llbnTDrWZpY2EgaW5kaWNhZGEgYWNpbWEsIGluY2x1c2l2ZSBvcyBkaXJlaXRvcwpkZSB2b3ogZSBpbWFnZW0gdmluY3VsYWRvcyDDoCBPQlJBLCBkdXJhbnRlIHRvZG8gbyBwcmF6byBkZSBkdXJhw6fDo28gZG9zIGRpcmVpdG9zIGF1dG9yYWlzLCBlbQpxdWFscXVlciBpZGlvbWEgZSBlbSB0b2RvcyBvcyBwYcOtc2VzOwoKKDIpIEFDRUlUQSBxdWUgYSBjZXNzw6NvIHRvdGFsIG7Do28gZXhjbHVzaXZhLCBwZXJtYW5lbnRlIGUgaXJyZXZvZ8OhdmVsIGRvcyBkaXJlaXRvcyBhdXRvcmFpcwpwYXRyaW1vbmlhaXMgbsOjbyBjb21lcmNpYWlzIGRlIHV0aWxpemHDp8OjbyBkZSBxdWUgdHJhdGEgZXN0ZSBkb2N1bWVudG8gaW5jbHVpLCBleGVtcGxpZmljYXRpdmFtZW50ZSwKb3MgZGlyZWl0b3MgZGUgZGlzcG9uaWJpbGl6YcOnw6NvIGUgY29tdW5pY2HDp8OjbyBww7pibGljYSBkYSBPQlJBLCBlbSBxdWFscXVlciBtZWlvIG91IHZlw61jdWxvLAppbmNsdXNpdmUgZW0gUmVwb3NpdMOzcmlvcyBEaWdpdGFpcywgYmVtIGNvbW8gb3MgZGlyZWl0b3MgZGUgcmVwcm9kdcOnw6NvLCBleGliacOnw6NvLCBleGVjdcOnw6NvLApkZWNsYW1hw6fDo28sIHJlY2l0YcOnw6NvLCBleHBvc2nDp8OjbywgYXJxdWl2YW1lbnRvLCBpbmNsdXPDo28gZW0gYmFuY28gZGUgZGFkb3MsIHByZXNlcnZhw6fDo28sIGRpZnVzw6NvLApkaXN0cmlidWnDp8OjbywgZGl2dWxnYcOnw6NvLCBlbXByw6lzdGltbywgdHJhZHXDp8OjbywgZHVibGFnZW0sIGxlZ2VuZGFnZW0sIGluY2x1c8OjbyBlbSBub3ZhcyBvYnJhcyBvdQpjb2xldMOibmVhcywgcmV1dGlsaXphw6fDo28sIGVkacOnw6NvLCBwcm9kdcOnw6NvIGRlIG1hdGVyaWFsIGRpZMOhdGljbyBlIGN1cnNvcyBvdSBxdWFscXVlciBmb3JtYSBkZQp1dGlsaXphw6fDo28gbsOjbyBjb21lcmNpYWw7CgooMykgUkVDT05IRUNFIHF1ZSBhIGNlc3PDo28gYXF1aSBlc3BlY2lmaWNhZGEgY29uY2VkZSDDoCBGSU9DUlVaIC0gRlVOREHDh8ODTyBPU1dBTERPCkNSVVogbyBkaXJlaXRvIGRlIGF1dG9yaXphciBxdWFscXVlciBwZXNzb2Eg4oCTIGbDrXNpY2Egb3UganVyw61kaWNhLCBww7pibGljYSBvdSBwcml2YWRhLCBuYWNpb25hbCBvdQplc3RyYW5nZWlyYSDigJMgYSBhY2Vzc2FyIGUgdXRpbGl6YXIgYW1wbGFtZW50ZSBhIE9CUkEsIHNlbSBleGNsdXNpdmlkYWRlLCBwYXJhIHF1YWlzcXVlcgpmaW5hbGlkYWRlcyBuw6NvIGNvbWVyY2lhaXM7CgooNCkgREVDTEFSQSBxdWUgYSBvYnJhIMOpIGNyaWHDp8OjbyBvcmlnaW5hbCBlIHF1ZSDDqSBvIHRpdHVsYXIgZG9zIGRpcmVpdG9zIGFxdWkgY2VkaWRvcyBlIGF1dG9yaXphZG9zLApyZXNwb25zYWJpbGl6YW5kby1zZSBpbnRlZ3JhbG1lbnRlIHBlbG8gY29udGXDumRvIGUgb3V0cm9zIGVsZW1lbnRvcyBxdWUgZmF6ZW0gcGFydGUgZGEgT0JSQSwKaW5jbHVzaXZlIG9zIGRpcmVpdG9zIGRlIHZveiBlIGltYWdlbSB2aW5jdWxhZG9zIMOgIE9CUkEsIG9icmlnYW5kby1zZSBhIGluZGVuaXphciB0ZXJjZWlyb3MgcG9yCmRhbm9zLCBiZW0gY29tbyBpbmRlbml6YXIgZSByZXNzYXJjaXIgYSBGSU9DUlVaIC0gRlVOREHDh8ODTyBPU1dBTERPIENSVVogZGUKZXZlbnR1YWlzIGRlc3Blc2FzIHF1ZSB2aWVyZW0gYSBzdXBvcnRhciwgZW0gcmF6w6NvIGRlIHF1YWxxdWVyIG9mZW5zYSBhIGRpcmVpdG9zIGF1dG9yYWlzIG91CmRpcmVpdG9zIGRlIHZveiBvdSBpbWFnZW0sIHByaW5jaXBhbG1lbnRlIG5vIHF1ZSBkaXogcmVzcGVpdG8gYSBwbMOhZ2lvIGUgdmlvbGHDp8O1ZXMgZGUgZGlyZWl0b3M7CgooNSkgQUZJUk1BIHF1ZSBjb25oZWNlIGEgUG9sw610aWNhIEluc3RpdHVjaW9uYWwgZGUgQWNlc3NvIEFiZXJ0byBkYSBGSU9DUlVaIC0gRlVOREHDh8ODTwpPU1dBTERPIENSVVogZSBhcyBkaXJldHJpemVzIHBhcmEgbyBmdW5jaW9uYW1lbnRvIGRvIHJlcG9zaXTDs3JpbyBpbnN0aXR1Y2lvbmFsIEFSQ0EuCgpBIFBvbMOtdGljYSBJbnN0aXR1Y2lvbmFsIGRlIEFjZXNzbyBBYmVydG8gZGEgRklPQ1JVWiAtIEZVTkRBw4fDg08gT1NXQUxETyBDUlVaIHJlc2VydmEKZXhjbHVzaXZhbWVudGUgYW8gQVVUT1Igb3MgZGlyZWl0b3MgbW9yYWlzIGUgb3MgdXNvcyBjb21lcmNpYWlzIHNvYnJlIGFzIG9icmFzIGRlIHN1YSBhdXRvcmlhCmUvb3UgdGl0dWxhcmlkYWRlLCBzZW5kbyBvcyB0ZXJjZWlyb3MgdXN1w6FyaW9zIHJlc3BvbnPDoXZlaXMgcGVsYSBhdHJpYnVpw6fDo28gZGUgYXV0b3JpYSBlIG1hbnV0ZW7Dp8OjbwpkYSBpbnRlZ3JpZGFkZSBkYSBPQlJBIGVtIHF1YWxxdWVyIHV0aWxpemHDp8Ojby4KCkEgUG9sw610aWNhIEluc3RpdHVjaW9uYWwgZGUgQWNlc3NvIEFiZXJ0byBkYSBGSU9DUlVaIC0gRlVOREHDh8ODTyBPU1dBTERPIENSVVoKcmVzcGVpdGEgb3MgY29udHJhdG9zIGUgYWNvcmRvcyBwcmVleGlzdGVudGVzIGRvcyBBdXRvcmVzIGNvbSB0ZXJjZWlyb3MsIGNhYmVuZG8gYW9zIEF1dG9yZXMKaW5mb3JtYXIgw6AgSW5zdGl0dWnDp8OjbyBhcyBjb25kacOnw7VlcyBlIG91dHJhcyByZXN0cmnDp8O1ZXMgaW1wb3N0YXMgcG9yIGVzdGVzIGluc3RydW1lbnRvcy4KRepositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-09-04T13:53:50Repositório Institucional da FIOCRUZ (ARCA) - 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dc.title.en_US.fl_str_mv |
Exposure to and infection by Leishmania infantum among domestic dogs in an area of the Cerrado biome, Maranhao, Brazil |
title |
Exposure to and infection by Leishmania infantum among domestic dogs in an area of the Cerrado biome, Maranhao, Brazil |
spellingShingle |
Exposure to and infection by Leishmania infantum among domestic dogs in an area of the Cerrado biome, Maranhao, Brazil Reis, Andrea Teles dos Fatores de Risco Epidemiologia Leishmania Leishmania Risk factors Epidemiology Leishmania |
title_short |
Exposure to and infection by Leishmania infantum among domestic dogs in an area of the Cerrado biome, Maranhao, Brazil |
title_full |
Exposure to and infection by Leishmania infantum among domestic dogs in an area of the Cerrado biome, Maranhao, Brazil |
title_fullStr |
Exposure to and infection by Leishmania infantum among domestic dogs in an area of the Cerrado biome, Maranhao, Brazil |
title_full_unstemmed |
Exposure to and infection by Leishmania infantum among domestic dogs in an area of the Cerrado biome, Maranhao, Brazil |
title_sort |
Exposure to and infection by Leishmania infantum among domestic dogs in an area of the Cerrado biome, Maranhao, Brazil |
author |
Reis, Andrea Teles dos |
author_facet |
Reis, Andrea Teles dos Silva, Carla Fernanda do Carmo Rocha, Thaís Bastos Coutinho, Danielle Jordany Barros Costa, Andréa Pereira da Costa, Francisco Borges Souza, Fernando Almeida Nogueira, Rita de Maria Seabra |
author_role |
author |
author2 |
Silva, Carla Fernanda do Carmo Rocha, Thaís Bastos Coutinho, Danielle Jordany Barros Costa, Andréa Pereira da Costa, Francisco Borges Souza, Fernando Almeida Nogueira, Rita de Maria Seabra |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Reis, Andrea Teles dos Silva, Carla Fernanda do Carmo Rocha, Thaís Bastos Coutinho, Danielle Jordany Barros Costa, Andréa Pereira da Costa, Francisco Borges Souza, Fernando Almeida Nogueira, Rita de Maria Seabra |
dc.subject.other.en_US.fl_str_mv |
Fatores de Risco Epidemiologia Leishmania |
topic |
Fatores de Risco Epidemiologia Leishmania Leishmania Risk factors Epidemiology Leishmania |
dc.subject.en.en_US.fl_str_mv |
Leishmania Risk factors Epidemiology |
dc.subject.es.en_US.fl_str_mv |
Leishmania |
description |
Universidade do Estado do Maranhão. São Luis, MA, Brasil. |
publishDate |
2023 |
dc.date.accessioned.fl_str_mv |
2023-05-10T12:39:09Z |
dc.date.available.fl_str_mv |
2023-05-10T12:39:09Z |
dc.date.issued.fl_str_mv |
2023 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
REIS, Andrea Teles dos et al. Exposure to and infection by Leishmania infantum among domestic dogs in an area of the Cerrado biome, Maranhao, Brasil. Veterinary Parasitology: Regional Studies and Reports, v.39, 100851, p. 1 - 6, 2023. |
dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/58277 |
dc.identifier.issn.en_US.fl_str_mv |
2405-9390 |
dc.identifier.eissn.none.fl_str_mv |
10.1016/j.vprsr.2023.100851 |
identifier_str_mv |
REIS, Andrea Teles dos et al. Exposure to and infection by Leishmania infantum among domestic dogs in an area of the Cerrado biome, Maranhao, Brasil. Veterinary Parasitology: Regional Studies and Reports, v.39, 100851, p. 1 - 6, 2023. 2405-9390 10.1016/j.vprsr.2023.100851 |
url |
https://www.arca.fiocruz.br/handle/icict/58277 |
dc.language.iso.fl_str_mv |
eng |
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eng |
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info:eu-repo/semantics/openAccess |
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openAccess |
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Elsevier B.V. |
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Elsevier B.V. |
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reponame:Repositório Institucional da FIOCRUZ (ARCA) instname:Fundação Oswaldo Cruz (FIOCRUZ) instacron:FIOCRUZ |
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