Immunosuppressants: implications in Orthodontics

Detalhes bibliográficos
Autor(a) principal: Santos,Rogério Lacerda dos
Data de Publicação: 2012
Outros Autores: Lacerda,Maria Cláudia Mesquita, Gonçalves,Renato Torres, Martins,Marco Aurélio, Souza,Margareth Maria Gomes de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Dental Press Journal of Orthodontics
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2176-94512012000200012
Resumo: INTRODUCTION: There are medications capable of affecting bone metabolism and the rate of tooth movement. Among these medications are the immunosuppressants, which act by repressing the action of T lymphocytes, however they can cause bone loss and consequently lead to osteoporosis. Osteoporosis is a common complication following kidney, heart, liver or lung transplantation. The immunosuppressant treatment for preventing organ rejection after transplantation, in general, includes glucocorticoids, cyclosporine, tacrolimus, and sirolimus. All these drugs can have jeopardizing effects on bone mineral homeostasis and consequently influence tooth movement. In recent years, however, the increasing use of immunosuppressants has raised questions about their effects on bone metabolism in patients undergoing orthodontic treatment. OBJECTIVE: The objective of this review study was to inform orthodontists about the influence of immunosuppressants on bone metabolism and tooth movement.
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spelling Immunosuppressants: implications in OrthodonticsImmunosuppressantTooth movementBoneINTRODUCTION: There are medications capable of affecting bone metabolism and the rate of tooth movement. Among these medications are the immunosuppressants, which act by repressing the action of T lymphocytes, however they can cause bone loss and consequently lead to osteoporosis. Osteoporosis is a common complication following kidney, heart, liver or lung transplantation. The immunosuppressant treatment for preventing organ rejection after transplantation, in general, includes glucocorticoids, cyclosporine, tacrolimus, and sirolimus. All these drugs can have jeopardizing effects on bone mineral homeostasis and consequently influence tooth movement. In recent years, however, the increasing use of immunosuppressants has raised questions about their effects on bone metabolism in patients undergoing orthodontic treatment. OBJECTIVE: The objective of this review study was to inform orthodontists about the influence of immunosuppressants on bone metabolism and tooth movement.Dental Press International2012-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S2176-94512012000200012Dental Press Journal of Orthodontics v.17 n.2 2012reponame:Dental Press Journal of Orthodonticsinstname:Dental Press International (DPI)instacron:DPI10.1590/S2176-94512012000200012info:eu-repo/semantics/openAccessSantos,Rogério Lacerda dosLacerda,Maria Cláudia MesquitaGonçalves,Renato TorresMartins,Marco AurélioSouza,Margareth Maria Gomes deeng2012-06-12T00:00:00Zoai:scielo:S2176-94512012000200012Revistahttp://www.scielo.br/dpjoONGhttps://old.scielo.br/oai/scielo-oai.phpartigos@dentalpress.com.br||davidnormando@hotmail.com2177-67092176-9451opendoar:2012-06-12T00:00Dental Press Journal of Orthodontics - Dental Press International (DPI)false
dc.title.none.fl_str_mv Immunosuppressants: implications in Orthodontics
title Immunosuppressants: implications in Orthodontics
spellingShingle Immunosuppressants: implications in Orthodontics
Santos,Rogério Lacerda dos
Immunosuppressant
Tooth movement
Bone
title_short Immunosuppressants: implications in Orthodontics
title_full Immunosuppressants: implications in Orthodontics
title_fullStr Immunosuppressants: implications in Orthodontics
title_full_unstemmed Immunosuppressants: implications in Orthodontics
title_sort Immunosuppressants: implications in Orthodontics
author Santos,Rogério Lacerda dos
author_facet Santos,Rogério Lacerda dos
Lacerda,Maria Cláudia Mesquita
Gonçalves,Renato Torres
Martins,Marco Aurélio
Souza,Margareth Maria Gomes de
author_role author
author2 Lacerda,Maria Cláudia Mesquita
Gonçalves,Renato Torres
Martins,Marco Aurélio
Souza,Margareth Maria Gomes de
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Santos,Rogério Lacerda dos
Lacerda,Maria Cláudia Mesquita
Gonçalves,Renato Torres
Martins,Marco Aurélio
Souza,Margareth Maria Gomes de
dc.subject.por.fl_str_mv Immunosuppressant
Tooth movement
Bone
topic Immunosuppressant
Tooth movement
Bone
description INTRODUCTION: There are medications capable of affecting bone metabolism and the rate of tooth movement. Among these medications are the immunosuppressants, which act by repressing the action of T lymphocytes, however they can cause bone loss and consequently lead to osteoporosis. Osteoporosis is a common complication following kidney, heart, liver or lung transplantation. The immunosuppressant treatment for preventing organ rejection after transplantation, in general, includes glucocorticoids, cyclosporine, tacrolimus, and sirolimus. All these drugs can have jeopardizing effects on bone mineral homeostasis and consequently influence tooth movement. In recent years, however, the increasing use of immunosuppressants has raised questions about their effects on bone metabolism in patients undergoing orthodontic treatment. OBJECTIVE: The objective of this review study was to inform orthodontists about the influence of immunosuppressants on bone metabolism and tooth movement.
publishDate 2012
dc.date.none.fl_str_mv 2012-04-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2176-94512012000200012
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2176-94512012000200012
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S2176-94512012000200012
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Dental Press International
publisher.none.fl_str_mv Dental Press International
dc.source.none.fl_str_mv Dental Press Journal of Orthodontics v.17 n.2 2012
reponame:Dental Press Journal of Orthodontics
instname:Dental Press International (DPI)
instacron:DPI
instname_str Dental Press International (DPI)
instacron_str DPI
institution DPI
reponame_str Dental Press Journal of Orthodontics
collection Dental Press Journal of Orthodontics
repository.name.fl_str_mv Dental Press Journal of Orthodontics - Dental Press International (DPI)
repository.mail.fl_str_mv artigos@dentalpress.com.br||davidnormando@hotmail.com
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