Effects cytotoxic and genotoxic of Psittacanthus acinarius and Psittacanthus cordatus (mistletoe) on Allium cepa
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Revista Fitos |
Texto Completo: | https://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/1312 |
Resumo: | This study assessed the cytotoxic and genotoxic potentials of extracts of Psittacanthus acinarius (Mart.) Mart. and Psittacanthus cordatus (Hoffmanns.) in the root cell cycle of Allium cepa L. Aqueous leaf extracts of P. acinarius and P. cordatus at three concentrations: 0.00, 5 and 20 mg/mL for 24 hours. Histological slides were prepared and mitotic indices (MI %) and chromosomal alteration indices (CAI %) were determined. Inhibitory effects of the aqueous extract of leaves of P. acinarius were observed in 46.33 and 46.00% at concentrations of 5 and 20 mg/mL, respectively, in relation to the control (62.83%), in addition to a higher chromosomal alteration index by 0.26% at a concentration of 20 mg/mL. In the aqueous extract of leaves of P. cordatus, the greatest inhibitory effects were 33.83 and 35.50% in the concentrations of 5 and 20 mg/mL, respectively, in relation to the control (88.16%) and the highest alteration index chromosomal (3.30%) at 5 mg/mL. The aqueous leaf extracts of P. acinarius and P. cordatus at concentration of 5 and 20 mg/mL inhibit MI %, reveal an irregular recovery or prevent it, and induce chromosomal alterations, suggesting cytotoxic and genotoxic effects on division of meristematic cells of A. cepa. |
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Effects cytotoxic and genotoxic of Psittacanthus acinarius and Psittacanthus cordatus (mistletoe) on Allium cepaEffects cytotoxic and genotoxic of Psittacanthus acinarius and Psittacanthus cordatus (mistletoe) on Allium cepaChromosomal alterationMedicinal mistletoeMitotic indexBioassaysThis study assessed the cytotoxic and genotoxic potentials of extracts of Psittacanthus acinarius (Mart.) Mart. and Psittacanthus cordatus (Hoffmanns.) in the root cell cycle of Allium cepa L. Aqueous leaf extracts of P. acinarius and P. cordatus at three concentrations: 0.00, 5 and 20 mg/mL for 24 hours. Histological slides were prepared and mitotic indices (MI %) and chromosomal alteration indices (CAI %) were determined. Inhibitory effects of the aqueous extract of leaves of P. acinarius were observed in 46.33 and 46.00% at concentrations of 5 and 20 mg/mL, respectively, in relation to the control (62.83%), in addition to a higher chromosomal alteration index by 0.26% at a concentration of 20 mg/mL. In the aqueous extract of leaves of P. cordatus, the greatest inhibitory effects were 33.83 and 35.50% in the concentrations of 5 and 20 mg/mL, respectively, in relation to the control (88.16%) and the highest alteration index chromosomal (3.30%) at 5 mg/mL. The aqueous leaf extracts of P. acinarius and P. cordatus at concentration of 5 and 20 mg/mL inhibit MI %, reveal an irregular recovery or prevent it, and induce chromosomal alterations, suggesting cytotoxic and genotoxic effects on division of meristematic cells of A. cepa.This study assessed the cytotoxic and genotoxic potentials of extracts of Psittacanthus acinarius (Mart.) Mart. and Psittacanthus cordatus (Hoffmanns.) in the root cell cycle of Allium cepa L. Aqueous leaf extracts of P. acinarius and P. cordatus at three concentrations: 0.00, 5 and 20 mg/mL for 24 hours. Histological slides were prepared and mitotic indices (MI %) and chromosomal alteration indices (CAI %) were determined. Inhibitory effects of the aqueous extract of leaves of P. acinarius were observed in 46.33 and 46.00% at concentrations of 5 and 20 mg/mL, respectively, in relation to the control (62.83%), in addition to a higher chromosomal alteration index by 0.26% at a concentration of 20 mg/mL. In the aqueous extract of leaves of P. cordatus, the greatest inhibitory effects were 33.83 and 35.50% in the concentrations of 5 and 20 mg/mL, respectively, in relation to the control (88.16%) and the highest alteration index chromosomal (3.30%) at 5 mg/mL. The aqueous leaf extracts of P. acinarius and P. cordatus at concentration of 5 and 20 mg/mL inhibit MI %, reveal an irregular recovery or prevent it, and induce chromosomal alterations, suggesting cytotoxic and genotoxic effects on division of meristematic cells of A. cepa.Centro de Inovação em Biodiversidade e Saúde - Farmanguinhos/Fiocruz2022-09-30info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdftext/htmltext/xmlhttps://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/131210.32712/2446-4775.2022.1312Revista Fitos; Vol. 16 No. 3 (2022); 305-314Revista Fitos; Vol. 16 Núm. 3 (2022); 305-314Revista Fitos; v. 16 n. 3 (2022); 305-3142446-47751808-9569reponame:Revista Fitosinstname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZenghttps://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/1312/1062https://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/1312/1063https://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/1312/1161Copyright (c) 2022 Revista Fitosinfo:eu-repo/semantics/openAccessSilva, Orivaldo Benedito daDestacio, Jéssica ChavesPaula, Glescieli RodriguesRodrigues, Fabiana Aparecida CaldartRieder, Arno2022-09-30T21:08:22Zoai:ojs.revistafitos.far.fiocruz.br:article/1312Revistahttps://revistafitos.far.fiocruz.br/index.php/revista-fitos/PUBhttp://revistafitos.far.fiocruz.br/index.php/revista-fitos/oairevistafitos@far.fiocruz.br || eugenio.telles@far.fiocruz.br2446-47752446-4775opendoar:2022-09-30T21:08:22Revista Fitos - Fundação Oswaldo Cruz (FIOCRUZ)false |
dc.title.none.fl_str_mv |
Effects cytotoxic and genotoxic of Psittacanthus acinarius and Psittacanthus cordatus (mistletoe) on Allium cepa Effects cytotoxic and genotoxic of Psittacanthus acinarius and Psittacanthus cordatus (mistletoe) on Allium cepa |
title |
Effects cytotoxic and genotoxic of Psittacanthus acinarius and Psittacanthus cordatus (mistletoe) on Allium cepa |
spellingShingle |
Effects cytotoxic and genotoxic of Psittacanthus acinarius and Psittacanthus cordatus (mistletoe) on Allium cepa Silva, Orivaldo Benedito da Chromosomal alteration Medicinal mistletoe Mitotic index Bioassays |
title_short |
Effects cytotoxic and genotoxic of Psittacanthus acinarius and Psittacanthus cordatus (mistletoe) on Allium cepa |
title_full |
Effects cytotoxic and genotoxic of Psittacanthus acinarius and Psittacanthus cordatus (mistletoe) on Allium cepa |
title_fullStr |
Effects cytotoxic and genotoxic of Psittacanthus acinarius and Psittacanthus cordatus (mistletoe) on Allium cepa |
title_full_unstemmed |
Effects cytotoxic and genotoxic of Psittacanthus acinarius and Psittacanthus cordatus (mistletoe) on Allium cepa |
title_sort |
Effects cytotoxic and genotoxic of Psittacanthus acinarius and Psittacanthus cordatus (mistletoe) on Allium cepa |
author |
Silva, Orivaldo Benedito da |
author_facet |
Silva, Orivaldo Benedito da Destacio, Jéssica Chaves Paula, Glescieli Rodrigues Rodrigues, Fabiana Aparecida Caldart Rieder, Arno |
author_role |
author |
author2 |
Destacio, Jéssica Chaves Paula, Glescieli Rodrigues Rodrigues, Fabiana Aparecida Caldart Rieder, Arno |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Silva, Orivaldo Benedito da Destacio, Jéssica Chaves Paula, Glescieli Rodrigues Rodrigues, Fabiana Aparecida Caldart Rieder, Arno |
dc.subject.por.fl_str_mv |
Chromosomal alteration Medicinal mistletoe Mitotic index Bioassays |
topic |
Chromosomal alteration Medicinal mistletoe Mitotic index Bioassays |
description |
This study assessed the cytotoxic and genotoxic potentials of extracts of Psittacanthus acinarius (Mart.) Mart. and Psittacanthus cordatus (Hoffmanns.) in the root cell cycle of Allium cepa L. Aqueous leaf extracts of P. acinarius and P. cordatus at three concentrations: 0.00, 5 and 20 mg/mL for 24 hours. Histological slides were prepared and mitotic indices (MI %) and chromosomal alteration indices (CAI %) were determined. Inhibitory effects of the aqueous extract of leaves of P. acinarius were observed in 46.33 and 46.00% at concentrations of 5 and 20 mg/mL, respectively, in relation to the control (62.83%), in addition to a higher chromosomal alteration index by 0.26% at a concentration of 20 mg/mL. In the aqueous extract of leaves of P. cordatus, the greatest inhibitory effects were 33.83 and 35.50% in the concentrations of 5 and 20 mg/mL, respectively, in relation to the control (88.16%) and the highest alteration index chromosomal (3.30%) at 5 mg/mL. The aqueous leaf extracts of P. acinarius and P. cordatus at concentration of 5 and 20 mg/mL inhibit MI %, reveal an irregular recovery or prevent it, and induce chromosomal alterations, suggesting cytotoxic and genotoxic effects on division of meristematic cells of A. cepa. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-09-30 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/1312 10.32712/2446-4775.2022.1312 |
url |
https://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/1312 |
identifier_str_mv |
10.32712/2446-4775.2022.1312 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/1312/1062 https://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/1312/1063 https://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/1312/1161 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2022 Revista Fitos info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2022 Revista Fitos |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf text/html text/xml |
dc.publisher.none.fl_str_mv |
Centro de Inovação em Biodiversidade e Saúde - Farmanguinhos/Fiocruz |
publisher.none.fl_str_mv |
Centro de Inovação em Biodiversidade e Saúde - Farmanguinhos/Fiocruz |
dc.source.none.fl_str_mv |
Revista Fitos; Vol. 16 No. 3 (2022); 305-314 Revista Fitos; Vol. 16 Núm. 3 (2022); 305-314 Revista Fitos; v. 16 n. 3 (2022); 305-314 2446-4775 1808-9569 reponame:Revista Fitos instname:Fundação Oswaldo Cruz (FIOCRUZ) instacron:FIOCRUZ |
instname_str |
Fundação Oswaldo Cruz (FIOCRUZ) |
instacron_str |
FIOCRUZ |
institution |
FIOCRUZ |
reponame_str |
Revista Fitos |
collection |
Revista Fitos |
repository.name.fl_str_mv |
Revista Fitos - Fundação Oswaldo Cruz (FIOCRUZ) |
repository.mail.fl_str_mv |
revistafitos@far.fiocruz.br || eugenio.telles@far.fiocruz.br |
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1798313476007919616 |