Severe idiopathic thrombocytopenic purpura due to Cytomegalovirus

• Autor(a) principal: Cordeiro, Leonardo Pessanha
• Data de Publicação: 2023
• Outros Autores: de Almeida Velasco, Leticia, Fraga Soares, Juliana, Araujo Zulchner, Marina
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Revista Científica da Faculdade de Medicina de Campos
• Texto Completo: https://revista.fmc.br/ojs/index.php/RCFMC/article/view/826
• topic: Púrpura Trombocitopênica Idiopática; Trombocitopenia; Citomegalovírus; Idiopathic thrombocytopenic purpura. Thrombocytopenia. Cytomegalovirus.

Idiopathic Thrombocytopenic Purpura (ITP) is an autoimmune condition characterized by antibody-mediated platelet destruction, most prevalent in the pediatric age group. The diagnosis is based on exclusion, demonstrating isolated thrombocytopenia and clinical signs, such as ecchymosis, menorrhagia and gingivorrhagia. This article highlights a case of ITP associated with cytomegalovirus infection in a 64-year-old man. His initial examination showed a thrombocytopenia of 5,000 10³/mm³ and his manifestations were hematoma on the palate and in the right cubital fossa, in addition to purpura in the upper and lower limbs and abdomen and episodes of melena, hematuria and epistaxis. Treatment with human immunoglobulin and corticotherapy was effective, evolving with increased platelet count and reduction of hematomas. As thrombocytopenia is an alteration common to several pathologies, it is necessary to carry out the differential diagnosis so that the treatment is started as early as possible in order to avoid the evolution to severe hemorrhagic conditions.