Phylogenetic analysis of human group C rotavirus in hospitalized children with gastroenteritis in Belém, Brazil

Detalhes bibliográficos
Autor(a) principal: Lobo, Patrícia dos Santos
Data de Publicação: 2016
Outros Autores: Guerra, Sylvia de Fátima dos Santos, Siqueira, Jones Anderson Monteiro, Soares, Luana da Silva, Gabbay, Yvone Benchimol, Linhares, Alexandre da Costa, Mascarenhas, Joana D'Arc Pereira
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Digital do Instituto Evandro Chagas (Patuá)
Texto Completo: https://patua.iec.gov.br/handle/iec/2423
Resumo: Group C rotavirus (RVC) is potentially an important pathogen associated with acute gastroenteritis (AG), especially in outbreaks. This study aims to detect and molecularly characterize RVC in hospitalized children with AG in Belém, Brazil. From May 2008 to April 2011, 279 stools were subjected to reverse-transcription polymerase chain reaction targeting VP7, VP6, VP4, and NSP4 genes. RVC positivity rate was 2.1 per cent (6/279) and phylogenetic analysis of positive samples yields genotype G4-P[2]-I2-E2. No evidence of zoonotic transmission and VP7 gene demonstrated close relationship with Asian strains. RVC surveillance is worth to expand information on evolutionary and epidemiological features of this virus.
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spelling Lobo, Patrícia dos SantosGuerra, Sylvia de Fátima dos SantosSiqueira, Jones Anderson MonteiroSoares, Luana da SilvaGabbay, Yvone BenchimolLinhares, Alexandre da CostaMascarenhas, Joana D'Arc Pereira2017-04-13T11:21:57Z2017-04-13T11:21:57Z2016LOBO, Patrícia dos Santos et al. Phylogenetic analysis of human group C rotavirus in hospitalized children with gastroenteritis in Belém, Brazil. Journal of Medical Virology, v. 88, n. 4, p. 728-733, Apr. 2016. DOI: https://doi.org/ 10.1002/jmv.243791096-9071https://patua.iec.gov.br/handle/iec/242310.1002/jmv.24379Group C rotavirus (RVC) is potentially an important pathogen associated with acute gastroenteritis (AG), especially in outbreaks. This study aims to detect and molecularly characterize RVC in hospitalized children with AG in Belém, Brazil. From May 2008 to April 2011, 279 stools were subjected to reverse-transcription polymerase chain reaction targeting VP7, VP6, VP4, and NSP4 genes. RVC positivity rate was 2.1 per cent (6/279) and phylogenetic analysis of positive samples yields genotype G4-P[2]-I2-E2. No evidence of zoonotic transmission and VP7 gene demonstrated close relationship with Asian strains. RVC surveillance is worth to expand information on evolutionary and epidemiological features of this virus.Federal University of Pará. Tropical Medicine Center. Belém, PA, Brasil.Federal University of Pará. Tropical Medicine Center. Belém, PA, Brasil.Ministério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil.Ministério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil.Ministério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil.Ministério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil.Ministério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. 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dc.title.pt_BR.fl_str_mv Phylogenetic analysis of human group C rotavirus in hospitalized children with gastroenteritis in Belém, Brazil
title Phylogenetic analysis of human group C rotavirus in hospitalized children with gastroenteritis in Belém, Brazil
spellingShingle Phylogenetic analysis of human group C rotavirus in hospitalized children with gastroenteritis in Belém, Brazil
Lobo, Patrícia dos Santos
Gastroenterite / epidemiologia
Gastroenterite / virologia
Rotavirus / classificação
Rotavirus / genética
Infecções por Rotavirus / epidemiologia
Infecções por Rotavirus / virologia
Genótipo
Criança Hospitalizada
Reação em Cadeia da Polimerase Via Transcriptase Reversa / métodos
Região Amazônica (BR)
title_short Phylogenetic analysis of human group C rotavirus in hospitalized children with gastroenteritis in Belém, Brazil
title_full Phylogenetic analysis of human group C rotavirus in hospitalized children with gastroenteritis in Belém, Brazil
title_fullStr Phylogenetic analysis of human group C rotavirus in hospitalized children with gastroenteritis in Belém, Brazil
title_full_unstemmed Phylogenetic analysis of human group C rotavirus in hospitalized children with gastroenteritis in Belém, Brazil
title_sort Phylogenetic analysis of human group C rotavirus in hospitalized children with gastroenteritis in Belém, Brazil
author Lobo, Patrícia dos Santos
author_facet Lobo, Patrícia dos Santos
Guerra, Sylvia de Fátima dos Santos
Siqueira, Jones Anderson Monteiro
Soares, Luana da Silva
Gabbay, Yvone Benchimol
Linhares, Alexandre da Costa
Mascarenhas, Joana D'Arc Pereira
author_role author
author2 Guerra, Sylvia de Fátima dos Santos
Siqueira, Jones Anderson Monteiro
Soares, Luana da Silva
Gabbay, Yvone Benchimol
Linhares, Alexandre da Costa
Mascarenhas, Joana D'Arc Pereira
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Lobo, Patrícia dos Santos
Guerra, Sylvia de Fátima dos Santos
Siqueira, Jones Anderson Monteiro
Soares, Luana da Silva
Gabbay, Yvone Benchimol
Linhares, Alexandre da Costa
Mascarenhas, Joana D'Arc Pereira
dc.subject.decsPrimary.pt_BR.fl_str_mv Gastroenterite / epidemiologia
Gastroenterite / virologia
Rotavirus / classificação
Rotavirus / genética
Infecções por Rotavirus / epidemiologia
Infecções por Rotavirus / virologia
Genótipo
Criança Hospitalizada
Reação em Cadeia da Polimerase Via Transcriptase Reversa / métodos
Região Amazônica (BR)
topic Gastroenterite / epidemiologia
Gastroenterite / virologia
Rotavirus / classificação
Rotavirus / genética
Infecções por Rotavirus / epidemiologia
Infecções por Rotavirus / virologia
Genótipo
Criança Hospitalizada
Reação em Cadeia da Polimerase Via Transcriptase Reversa / métodos
Região Amazônica (BR)
description Group C rotavirus (RVC) is potentially an important pathogen associated with acute gastroenteritis (AG), especially in outbreaks. This study aims to detect and molecularly characterize RVC in hospitalized children with AG in Belém, Brazil. From May 2008 to April 2011, 279 stools were subjected to reverse-transcription polymerase chain reaction targeting VP7, VP6, VP4, and NSP4 genes. RVC positivity rate was 2.1 per cent (6/279) and phylogenetic analysis of positive samples yields genotype G4-P[2]-I2-E2. No evidence of zoonotic transmission and VP7 gene demonstrated close relationship with Asian strains. RVC surveillance is worth to expand information on evolutionary and epidemiological features of this virus.
publishDate 2016
dc.date.issued.fl_str_mv 2016
dc.date.accessioned.fl_str_mv 2017-04-13T11:21:57Z
dc.date.available.fl_str_mv 2017-04-13T11:21:57Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv LOBO, Patrícia dos Santos et al. Phylogenetic analysis of human group C rotavirus in hospitalized children with gastroenteritis in Belém, Brazil. Journal of Medical Virology, v. 88, n. 4, p. 728-733, Apr. 2016. DOI: https://doi.org/ 10.1002/jmv.24379
dc.identifier.uri.fl_str_mv https://patua.iec.gov.br/handle/iec/2423
dc.identifier.issn.-.fl_str_mv 1096-9071
dc.identifier.doi.-.fl_str_mv 10.1002/jmv.24379
identifier_str_mv LOBO, Patrícia dos Santos et al. Phylogenetic analysis of human group C rotavirus in hospitalized children with gastroenteritis in Belém, Brazil. Journal of Medical Virology, v. 88, n. 4, p. 728-733, Apr. 2016. DOI: https://doi.org/ 10.1002/jmv.24379
1096-9071
10.1002/jmv.24379
url https://patua.iec.gov.br/handle/iec/2423
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