Rural residence remains a risk factor for Toxoplasma infection among pregnant women in a highly urbanized Brazilian area: a robust cross-sectional study
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Digital do Instituto Evandro Chagas (Patuá) |
Texto Completo: | https://patua.iec.gov.br/handle/iec/4430 |
Resumo: | BACKGROUND: Despite high seroprevalence of asymptomatic infection in humans, toxoplasmosis can manifest as a severe systemic disease, as occurs in the congenital infection. Here we evaluate the seroprevalence of Toxoplasma infection among pregnant women in a highly urbanized area of Brazil. METHODS: A robust seroepidemiological study was conducted using laboratory databases of anti-Toxoplasma gondii serological results together with information on age, month/year of diagnosis and place of residence of pregnant women in the public health system of the city of Juiz de Fora, Brazil. RESULTS: Of 5895 pregnant women analysed, 54.7% showed seronegativity and 44.4% showed seropositivity for immunoglobulin G (IgG) antibodies against Toxoplasma gondii. This seropositivity rate increased to 68.3% when only considering participants from rural areas. Multivariate analysis revealed higher odds of being seropositive associated with age (odds ratio [OR] 1.06 [confidence interval {CI} 1.05 to 1.07]) and with living in rural areas (OR 2.96 [CI 1.64 to 5.36]). The spatial distribution of IgG seropositivity indicated a higher prevalence concentrated in rural and peripheral neighbourhoods. CONCLUSIONS: This is the first report to use spatial analysis to show a cluster of Toxoplasma infection in rural and peripheral neighbourhoods of a highly urbanized municipality, which highlights the need for adequate healthcare actions to be implemented for women living in these areas. |
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Antinarelli, Luciana Maria RibeiroSilva, Márcio RobertoGuimarães, Ricardo José de Paula Souza eTerror, Mariana SequettoLima, Patrícia EnhamIshii, Joelma de Souza CoimbraMuniz, Patrícia FabianoCoimbra, Elaine Soares2021-08-30T12:46:21Z2021-08-30T12:46:21Z2021ANTINARELLI, Luciana Maria Ribeiro et al. Rural residence remains a risk factor for Toxoplasma infection among pregnant women in a highly urbanized Brazilian area: a robust cross-sectional study. Transactions of the Royal Society of Tropical Medicine and Hygiene, v. 115, n. 8, p. 896-903, Aug. 2021.1878-3503https://patua.iec.gov.br/handle/iec/443010.1093/trstmh/traa153BACKGROUND: Despite high seroprevalence of asymptomatic infection in humans, toxoplasmosis can manifest as a severe systemic disease, as occurs in the congenital infection. Here we evaluate the seroprevalence of Toxoplasma infection among pregnant women in a highly urbanized area of Brazil. METHODS: A robust seroepidemiological study was conducted using laboratory databases of anti-Toxoplasma gondii serological results together with information on age, month/year of diagnosis and place of residence of pregnant women in the public health system of the city of Juiz de Fora, Brazil. RESULTS: Of 5895 pregnant women analysed, 54.7% showed seronegativity and 44.4% showed seropositivity for immunoglobulin G (IgG) antibodies against Toxoplasma gondii. This seropositivity rate increased to 68.3% when only considering participants from rural areas. Multivariate analysis revealed higher odds of being seropositive associated with age (odds ratio [OR] 1.06 [confidence interval {CI} 1.05 to 1.07]) and with living in rural areas (OR 2.96 [CI 1.64 to 5.36]). The spatial distribution of IgG seropositivity indicated a higher prevalence concentrated in rural and peripheral neighbourhoods. CONCLUSIONS: This is the first report to use spatial analysis to show a cluster of Toxoplasma infection in rural and peripheral neighbourhoods of a highly urbanized municipality, which highlights the need for adequate healthcare actions to be implemented for women living in these areas.Universidade Federal de Minas Gerais. Faculdade de Medicina. Programa de Pós-Graduação em Ciências da Saúde: Infectologia e Medicina Tropical. Belo Horizonte, MG, Brazil / Laboratório Central da Prefeitura de Juiz de Fora. Juiz de Fora, MG, Brazil.Embrapa Gado de Leite. Juiz de Fora, MG, Brazil.Ministério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Laboratório de Geoprocessamento. Ananindeua, PA, Brasil.Universidade Federal de Juiz de Fora. Departamento de Parasitologia, Microbiologia e Imunologia. Juiz de Fora, MG, Brazil.Laboratório Central da Prefeitura de Juiz de Fora. Juiz de Fora, MG, Brazil.Laboratório Central da Prefeitura de Juiz de Fora. Juiz de Fora, MG, Brazil.Laboratório Central da Prefeitura de Juiz de Fora. Juiz de Fora, MG, Brazil.Universidade Federal de Juiz de Fora. Departamento de Parasitologia, Microbiologia e Imunologia. Juiz de Fora, MG, Brazil.engOxford University PressRural residence remains a risk factor for Toxoplasma infection among pregnant women in a highly urbanized Brazilian area: a robust cross-sectional studyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleToxoplasmose Congênita / patologiaToxoplasmose Congênita / transmissãoGestantesEstudos SoroepidemiológicosZona Ruralinfo:eu-repo/semantics/embargoedAccessreponame:Repositório Digital do Instituto Evandro Chagas (Patuá)instname:Instituto Evandro Chagas (IEC)instacron:IECLICENSElicense.txtlicense.txttext/plain; charset=utf-82182https://patua.iec.gov.br/bitstreams/4cabd432-5fcd-4e9c-a79f-266ff871a8a0/download11832eea31b16df8613079d742d61793MD52ORIGINALRural residence remains a risk factor for Toxoplasma infection among pregnant women in a highly urbanized Brazilian area: a robust cross-sectional study.pdfRural residence remains a risk factor for Toxoplasma infection among pregnant women in a highly urbanized Brazilian area: a robust cross-sectional study.pdfapplication/pdf551083https://patua.iec.gov.br/bitstreams/1b296910-ab9b-45ad-9a74-949fe4e9c0e6/downloadc9a9c128e29cac82a5d7fdf3f4e6da73MD51TEXTRural residence remains a risk factor for Toxoplasma infection among pregnant women in a highly urbanized Brazilian area: a robust cross-sectional study.pdf.txtRural residence remains a risk factor for Toxoplasma infection among pregnant women in a highly urbanized Brazilian area: a robust cross-sectional study.pdf.txtExtracted texttext/plain2https://patua.iec.gov.br/bitstreams/4d305343-bd2b-402d-ae63-53b613a4eab6/downloade1c06d85ae7b8b032bef47e42e4c08f9MD55THUMBNAILRural residence remains a risk factor for Toxoplasma infection among pregnant women in a highly urbanized Brazilian area: a robust cross-sectional study.pdf.jpgRural residence remains a risk factor for Toxoplasma infection among pregnant women in a highly urbanized Brazilian area: a robust cross-sectional study.pdf.jpgGenerated Thumbnailimage/jpeg3095https://patua.iec.gov.br/bitstreams/b71a034c-493d-4d26-a7f3-e544c2dceaa8/download71859d578212107f7f8c49a4ce09d9eeMD56iec/44302022-10-20 22:19:46.34oai:patua.iec.gov.br:iec/4430https://patua.iec.gov.brRepositório InstitucionalPUBhttps://patua.iec.gov.br/oai/requestclariceneta@iec.gov.br || Biblioteca@iec.gov.bropendoar:2022-10-20T22:19:46Repositório Digital do Instituto Evandro Chagas (Patuá) - 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dc.title.pt_BR.fl_str_mv |
Rural residence remains a risk factor for Toxoplasma infection among pregnant women in a highly urbanized Brazilian area: a robust cross-sectional study |
title |
Rural residence remains a risk factor for Toxoplasma infection among pregnant women in a highly urbanized Brazilian area: a robust cross-sectional study |
spellingShingle |
Rural residence remains a risk factor for Toxoplasma infection among pregnant women in a highly urbanized Brazilian area: a robust cross-sectional study Antinarelli, Luciana Maria Ribeiro Toxoplasmose Congênita / patologia Toxoplasmose Congênita / transmissão Gestantes Estudos Soroepidemiológicos Zona Rural |
title_short |
Rural residence remains a risk factor for Toxoplasma infection among pregnant women in a highly urbanized Brazilian area: a robust cross-sectional study |
title_full |
Rural residence remains a risk factor for Toxoplasma infection among pregnant women in a highly urbanized Brazilian area: a robust cross-sectional study |
title_fullStr |
Rural residence remains a risk factor for Toxoplasma infection among pregnant women in a highly urbanized Brazilian area: a robust cross-sectional study |
title_full_unstemmed |
Rural residence remains a risk factor for Toxoplasma infection among pregnant women in a highly urbanized Brazilian area: a robust cross-sectional study |
title_sort |
Rural residence remains a risk factor for Toxoplasma infection among pregnant women in a highly urbanized Brazilian area: a robust cross-sectional study |
author |
Antinarelli, Luciana Maria Ribeiro |
author_facet |
Antinarelli, Luciana Maria Ribeiro Silva, Márcio Roberto Guimarães, Ricardo José de Paula Souza e Terror, Mariana Sequetto Lima, Patrícia Enham Ishii, Joelma de Souza Coimbra Muniz, Patrícia Fabiano Coimbra, Elaine Soares |
author_role |
author |
author2 |
Silva, Márcio Roberto Guimarães, Ricardo José de Paula Souza e Terror, Mariana Sequetto Lima, Patrícia Enham Ishii, Joelma de Souza Coimbra Muniz, Patrícia Fabiano Coimbra, Elaine Soares |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Antinarelli, Luciana Maria Ribeiro Silva, Márcio Roberto Guimarães, Ricardo José de Paula Souza e Terror, Mariana Sequetto Lima, Patrícia Enham Ishii, Joelma de Souza Coimbra Muniz, Patrícia Fabiano Coimbra, Elaine Soares |
dc.subject.decsPrimary.pt_BR.fl_str_mv |
Toxoplasmose Congênita / patologia Toxoplasmose Congênita / transmissão Gestantes Estudos Soroepidemiológicos Zona Rural |
topic |
Toxoplasmose Congênita / patologia Toxoplasmose Congênita / transmissão Gestantes Estudos Soroepidemiológicos Zona Rural |
description |
BACKGROUND: Despite high seroprevalence of asymptomatic infection in humans, toxoplasmosis can manifest as a severe systemic disease, as occurs in the congenital infection. Here we evaluate the seroprevalence of Toxoplasma infection among pregnant women in a highly urbanized area of Brazil. METHODS: A robust seroepidemiological study was conducted using laboratory databases of anti-Toxoplasma gondii serological results together with information on age, month/year of diagnosis and place of residence of pregnant women in the public health system of the city of Juiz de Fora, Brazil. RESULTS: Of 5895 pregnant women analysed, 54.7% showed seronegativity and 44.4% showed seropositivity for immunoglobulin G (IgG) antibodies against Toxoplasma gondii. This seropositivity rate increased to 68.3% when only considering participants from rural areas. Multivariate analysis revealed higher odds of being seropositive associated with age (odds ratio [OR] 1.06 [confidence interval {CI} 1.05 to 1.07]) and with living in rural areas (OR 2.96 [CI 1.64 to 5.36]). The spatial distribution of IgG seropositivity indicated a higher prevalence concentrated in rural and peripheral neighbourhoods. CONCLUSIONS: This is the first report to use spatial analysis to show a cluster of Toxoplasma infection in rural and peripheral neighbourhoods of a highly urbanized municipality, which highlights the need for adequate healthcare actions to be implemented for women living in these areas. |
publishDate |
2021 |
dc.date.accessioned.fl_str_mv |
2021-08-30T12:46:21Z |
dc.date.available.fl_str_mv |
2021-08-30T12:46:21Z |
dc.date.issued.fl_str_mv |
2021 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
ANTINARELLI, Luciana Maria Ribeiro et al. Rural residence remains a risk factor for Toxoplasma infection among pregnant women in a highly urbanized Brazilian area: a robust cross-sectional study. Transactions of the Royal Society of Tropical Medicine and Hygiene, v. 115, n. 8, p. 896-903, Aug. 2021. |
dc.identifier.uri.fl_str_mv |
https://patua.iec.gov.br/handle/iec/4430 |
dc.identifier.issn.-.fl_str_mv |
1878-3503 |
dc.identifier.doi.-.fl_str_mv |
10.1093/trstmh/traa153 |
identifier_str_mv |
ANTINARELLI, Luciana Maria Ribeiro et al. Rural residence remains a risk factor for Toxoplasma infection among pregnant women in a highly urbanized Brazilian area: a robust cross-sectional study. Transactions of the Royal Society of Tropical Medicine and Hygiene, v. 115, n. 8, p. 896-903, Aug. 2021. 1878-3503 10.1093/trstmh/traa153 |
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https://patua.iec.gov.br/handle/iec/4430 |
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eng |
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eng |
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Oxford University Press |
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Oxford University Press |
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