Potential recurrence of COVID-19 in a healthcare professional: SARS-CoV-2 genome sequencing confirms contagiousness after re-positivity

Detalhes bibliográficos
Autor(a) principal: Correia, Ana M.
Data de Publicação: 2021
Outros Autores: Borges, Vítor, Isidro, Joana, Lima, Ana R., Fernandes, Alberto, Godinho, Maria Leonor, Duarte, Sílvia, Ferrão, José, Vieira, Luís, Gomes, João P.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.18/8055
Resumo: Re-positivity of SARS-CoV-2 tests is widely reported, raising discussion about guidance for patient discharge and ending isolation. The unsuccessful recovery of replication-competent virus and/or absence of secondary cases has suggested that re-positive patients are not contagious. This study reports SARS-CoV-2 re-positivity in a healthcare professional 16 days after three negative tests, with viral genome sequencing supporting contagiousness leading to secondary cases.
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spelling Potential recurrence of COVID-19 in a healthcare professional: SARS-CoV-2 genome sequencing confirms contagiousness after re-positivityCOVID-19Genome SequencingInfectivityRe-positivitySARS-CoV-2Infecções RespiratóriasCuidados de SaúdeRe-positivity of SARS-CoV-2 tests is widely reported, raising discussion about guidance for patient discharge and ending isolation. The unsuccessful recovery of replication-competent virus and/or absence of secondary cases has suggested that re-positive patients are not contagious. This study reports SARS-CoV-2 re-positivity in a healthcare professional 16 days after three negative tests, with viral genome sequencing supporting contagiousness leading to secondary cases.Highlights: - SARS-CoV-2 re-positivity tests are widely reported; Re-positive patients are assumed not to be contagious; Genome sequencing supported contagiousness from a re-positive patient to contacts.ElsevierRepositório Científico do Instituto Nacional de SaúdeCorreia, Ana M.Borges, VítorIsidro, JoanaLima, Ana R.Fernandes, AlbertoGodinho, Maria LeonorDuarte, SílviaFerrão, JoséVieira, LuísGomes, João P.2022-07-04T16:30:03Z2021-09-202021-09-20T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.18/8055engInt J Infect Dis. 2021 Nov;112:318-320. doi: 10.1016/j.ijid.2021.09.035. Epub 2021 Sep 20.1201-971210.1016/j.ijid.2021.09.035info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-20T15:42:25Zoai:repositorio.insa.pt:10400.18/8055Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:42:50.200432Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Potential recurrence of COVID-19 in a healthcare professional: SARS-CoV-2 genome sequencing confirms contagiousness after re-positivity
title Potential recurrence of COVID-19 in a healthcare professional: SARS-CoV-2 genome sequencing confirms contagiousness after re-positivity
spellingShingle Potential recurrence of COVID-19 in a healthcare professional: SARS-CoV-2 genome sequencing confirms contagiousness after re-positivity
Correia, Ana M.
COVID-19
Genome Sequencing
Infectivity
Re-positivity
SARS-CoV-2
Infecções Respiratórias
Cuidados de Saúde
title_short Potential recurrence of COVID-19 in a healthcare professional: SARS-CoV-2 genome sequencing confirms contagiousness after re-positivity
title_full Potential recurrence of COVID-19 in a healthcare professional: SARS-CoV-2 genome sequencing confirms contagiousness after re-positivity
title_fullStr Potential recurrence of COVID-19 in a healthcare professional: SARS-CoV-2 genome sequencing confirms contagiousness after re-positivity
title_full_unstemmed Potential recurrence of COVID-19 in a healthcare professional: SARS-CoV-2 genome sequencing confirms contagiousness after re-positivity
title_sort Potential recurrence of COVID-19 in a healthcare professional: SARS-CoV-2 genome sequencing confirms contagiousness after re-positivity
author Correia, Ana M.
author_facet Correia, Ana M.
Borges, Vítor
Isidro, Joana
Lima, Ana R.
Fernandes, Alberto
Godinho, Maria Leonor
Duarte, Sílvia
Ferrão, José
Vieira, Luís
Gomes, João P.
author_role author
author2 Borges, Vítor
Isidro, Joana
Lima, Ana R.
Fernandes, Alberto
Godinho, Maria Leonor
Duarte, Sílvia
Ferrão, José
Vieira, Luís
Gomes, João P.
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório Científico do Instituto Nacional de Saúde
dc.contributor.author.fl_str_mv Correia, Ana M.
Borges, Vítor
Isidro, Joana
Lima, Ana R.
Fernandes, Alberto
Godinho, Maria Leonor
Duarte, Sílvia
Ferrão, José
Vieira, Luís
Gomes, João P.
dc.subject.por.fl_str_mv COVID-19
Genome Sequencing
Infectivity
Re-positivity
SARS-CoV-2
Infecções Respiratórias
Cuidados de Saúde
topic COVID-19
Genome Sequencing
Infectivity
Re-positivity
SARS-CoV-2
Infecções Respiratórias
Cuidados de Saúde
description Re-positivity of SARS-CoV-2 tests is widely reported, raising discussion about guidance for patient discharge and ending isolation. The unsuccessful recovery of replication-competent virus and/or absence of secondary cases has suggested that re-positive patients are not contagious. This study reports SARS-CoV-2 re-positivity in a healthcare professional 16 days after three negative tests, with viral genome sequencing supporting contagiousness leading to secondary cases.
publishDate 2021
dc.date.none.fl_str_mv 2021-09-20
2021-09-20T00:00:00Z
2022-07-04T16:30:03Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.18/8055
url http://hdl.handle.net/10400.18/8055
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Int J Infect Dis. 2021 Nov;112:318-320. doi: 10.1016/j.ijid.2021.09.035. Epub 2021 Sep 20.
1201-9712
10.1016/j.ijid.2021.09.035
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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