Procalcitonin kinetics after burn injury and burn surgery in septic and non-septic patients - a retrospective observational study

Detalhes bibliográficos
Autor(a) principal: Cabral, Luís
Data de Publicação: 2018
Outros Autores: Afreixo, Vera, Meireles, Rita, Vaz, Miguel, Marques, Margarida, Tourais, Isabel, Chaves, Catarina, Almeida, Luís, Paiva, José Artur
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10773/24652
Resumo: Early sepsis diagnosis is crucial for the correct management of burn patients, and it clearly influences outcomes. The systemic inflammatory response triggered by burns mimics sepsis presentation and complicates early sepsis diagnosis. Biomarkers were advocated to aid the diagnosis of early sepsis. Serum procalcitonin (PCT) exhibits fair accuracy and good correlation with sepsis severity, being used in diverse clinical settings. However, few studies have evaluated perioperative changes in PCT levels in burn patients. The present study evaluated PCT kinetics during the first days after burn injury and subsequent surgical interventions to assess PCT utility in distinguishing septic from non-septic inflammatory responses.
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spelling Procalcitonin kinetics after burn injury and burn surgery in septic and non-septic patients - a retrospective observational studyBurnsProcalcitoninSepsisSurgeryEarly sepsis diagnosis is crucial for the correct management of burn patients, and it clearly influences outcomes. The systemic inflammatory response triggered by burns mimics sepsis presentation and complicates early sepsis diagnosis. Biomarkers were advocated to aid the diagnosis of early sepsis. Serum procalcitonin (PCT) exhibits fair accuracy and good correlation with sepsis severity, being used in diverse clinical settings. However, few studies have evaluated perioperative changes in PCT levels in burn patients. The present study evaluated PCT kinetics during the first days after burn injury and subsequent surgical interventions to assess PCT utility in distinguishing septic from non-septic inflammatory responses.BMC2018-11-16T11:10:43Z2018-09-05T00:00:00Z2018-09-05info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10773/24652eng10.1186/s12871-018-0585-6Cabral, LuísAfreixo, VeraMeireles, RitaVaz, MiguelMarques, MargaridaTourais, IsabelChaves, CatarinaAlmeida, LuísPaiva, José Arturinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-02-22T11:48:04Zoai:ria.ua.pt:10773/24652Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T02:58:10.937898Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Procalcitonin kinetics after burn injury and burn surgery in septic and non-septic patients - a retrospective observational study
title Procalcitonin kinetics after burn injury and burn surgery in septic and non-septic patients - a retrospective observational study
spellingShingle Procalcitonin kinetics after burn injury and burn surgery in septic and non-septic patients - a retrospective observational study
Cabral, Luís
Burns
Procalcitonin
Sepsis
Surgery
title_short Procalcitonin kinetics after burn injury and burn surgery in septic and non-septic patients - a retrospective observational study
title_full Procalcitonin kinetics after burn injury and burn surgery in septic and non-septic patients - a retrospective observational study
title_fullStr Procalcitonin kinetics after burn injury and burn surgery in septic and non-septic patients - a retrospective observational study
title_full_unstemmed Procalcitonin kinetics after burn injury and burn surgery in septic and non-septic patients - a retrospective observational study
title_sort Procalcitonin kinetics after burn injury and burn surgery in septic and non-septic patients - a retrospective observational study
author Cabral, Luís
author_facet Cabral, Luís
Afreixo, Vera
Meireles, Rita
Vaz, Miguel
Marques, Margarida
Tourais, Isabel
Chaves, Catarina
Almeida, Luís
Paiva, José Artur
author_role author
author2 Afreixo, Vera
Meireles, Rita
Vaz, Miguel
Marques, Margarida
Tourais, Isabel
Chaves, Catarina
Almeida, Luís
Paiva, José Artur
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Cabral, Luís
Afreixo, Vera
Meireles, Rita
Vaz, Miguel
Marques, Margarida
Tourais, Isabel
Chaves, Catarina
Almeida, Luís
Paiva, José Artur
dc.subject.por.fl_str_mv Burns
Procalcitonin
Sepsis
Surgery
topic Burns
Procalcitonin
Sepsis
Surgery
description Early sepsis diagnosis is crucial for the correct management of burn patients, and it clearly influences outcomes. The systemic inflammatory response triggered by burns mimics sepsis presentation and complicates early sepsis diagnosis. Biomarkers were advocated to aid the diagnosis of early sepsis. Serum procalcitonin (PCT) exhibits fair accuracy and good correlation with sepsis severity, being used in diverse clinical settings. However, few studies have evaluated perioperative changes in PCT levels in burn patients. The present study evaluated PCT kinetics during the first days after burn injury and subsequent surgical interventions to assess PCT utility in distinguishing septic from non-septic inflammatory responses.
publishDate 2018
dc.date.none.fl_str_mv 2018-11-16T11:10:43Z
2018-09-05T00:00:00Z
2018-09-05
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10773/24652
url http://hdl.handle.net/10773/24652
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1186/s12871-018-0585-6
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv BMC
publisher.none.fl_str_mv BMC
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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