Antibacterial potential of Northeastern Portugal wild plant extracts and respective phenolic compounds

Detalhes bibliográficos
Autor(a) principal: Pinho, Eva
Data de Publicação: 2014
Outros Autores: Ferreira, Isabel C.F.R., Barros, Lillian, Carvalho, Ana Maria, Soares, Graça, Henriques, Mariana
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10198/10154
Resumo: The present work aims to assess the antibacterial potential of phenolic extracts, recovered from plants obtained on the North East of Portugal, and of their phenolic compounds (ellagic, caffeic, and gallic acids, quercetin, kaempferol, and rutin), against bacteria commonly found on skin infections. The disk diffusion and the susceptibility assays were used to identify the most active extracts and phenolic compounds. The effect of selected phenolic compounds on animal cells was assessed by determination of cellular metabolic activity. Gallic acid had a higher activity, against gram-positive (S. epidermidis and S. aureus) and gram-negative bacteria (K. pneumoniae) at lower concentrations, than the other compounds. The caffeic acid, also, showed good antibacterial activity against the 3 bacteria used. The gallic acid was effective against the 3 bacteria without causing harm to the animal cells. Gallic and caffeic acid showed a promising applicability as antibacterial agents for the treatment of infected wounds.
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spelling Antibacterial potential of Northeastern Portugal wild plant extracts and respective phenolic compoundsThe present work aims to assess the antibacterial potential of phenolic extracts, recovered from plants obtained on the North East of Portugal, and of their phenolic compounds (ellagic, caffeic, and gallic acids, quercetin, kaempferol, and rutin), against bacteria commonly found on skin infections. The disk diffusion and the susceptibility assays were used to identify the most active extracts and phenolic compounds. The effect of selected phenolic compounds on animal cells was assessed by determination of cellular metabolic activity. Gallic acid had a higher activity, against gram-positive (S. epidermidis and S. aureus) and gram-negative bacteria (K. pneumoniae) at lower concentrations, than the other compounds. The caffeic acid, also, showed good antibacterial activity against the 3 bacteria used. The gallic acid was effective against the 3 bacteria without causing harm to the animal cells. Gallic and caffeic acid showed a promising applicability as antibacterial agents for the treatment of infected wounds.HindawiBiblioteca Digital do IPBPinho, EvaFerreira, Isabel C.F.R.Barros, LillianCarvalho, Ana MariaSoares, GraçaHenriques, Mariana2014-08-14T09:24:51Z20142014-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10198/10154engPinho, Eva; Ferreira, Isabel C.F.R.; Barros, Lillian; Carvalho, Ana Maria; Soares, Graça; Henriques, Mariana (2014). Antibacterial potential of North-eastern Portugal wild plant extracts and respective phenolic compounds. BioMed Research International. ISSN 2314-6141. p. 1-72314-614110.1155/2014/814590info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-01-16T12:12:14ZPortal AgregadorONG
dc.title.none.fl_str_mv Antibacterial potential of Northeastern Portugal wild plant extracts and respective phenolic compounds
title Antibacterial potential of Northeastern Portugal wild plant extracts and respective phenolic compounds
spellingShingle Antibacterial potential of Northeastern Portugal wild plant extracts and respective phenolic compounds
Pinho, Eva
title_short Antibacterial potential of Northeastern Portugal wild plant extracts and respective phenolic compounds
title_full Antibacterial potential of Northeastern Portugal wild plant extracts and respective phenolic compounds
title_fullStr Antibacterial potential of Northeastern Portugal wild plant extracts and respective phenolic compounds
title_full_unstemmed Antibacterial potential of Northeastern Portugal wild plant extracts and respective phenolic compounds
title_sort Antibacterial potential of Northeastern Portugal wild plant extracts and respective phenolic compounds
author Pinho, Eva
author_facet Pinho, Eva
Ferreira, Isabel C.F.R.
Barros, Lillian
Carvalho, Ana Maria
Soares, Graça
Henriques, Mariana
author_role author
author2 Ferreira, Isabel C.F.R.
Barros, Lillian
Carvalho, Ana Maria
Soares, Graça
Henriques, Mariana
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Biblioteca Digital do IPB
dc.contributor.author.fl_str_mv Pinho, Eva
Ferreira, Isabel C.F.R.
Barros, Lillian
Carvalho, Ana Maria
Soares, Graça
Henriques, Mariana
description The present work aims to assess the antibacterial potential of phenolic extracts, recovered from plants obtained on the North East of Portugal, and of their phenolic compounds (ellagic, caffeic, and gallic acids, quercetin, kaempferol, and rutin), against bacteria commonly found on skin infections. The disk diffusion and the susceptibility assays were used to identify the most active extracts and phenolic compounds. The effect of selected phenolic compounds on animal cells was assessed by determination of cellular metabolic activity. Gallic acid had a higher activity, against gram-positive (S. epidermidis and S. aureus) and gram-negative bacteria (K. pneumoniae) at lower concentrations, than the other compounds. The caffeic acid, also, showed good antibacterial activity against the 3 bacteria used. The gallic acid was effective against the 3 bacteria without causing harm to the animal cells. Gallic and caffeic acid showed a promising applicability as antibacterial agents for the treatment of infected wounds.
publishDate 2014
dc.date.none.fl_str_mv 2014-08-14T09:24:51Z
2014
2014-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10198/10154
url http://hdl.handle.net/10198/10154
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Pinho, Eva; Ferreira, Isabel C.F.R.; Barros, Lillian; Carvalho, Ana Maria; Soares, Graça; Henriques, Mariana (2014). Antibacterial potential of North-eastern Portugal wild plant extracts and respective phenolic compounds. BioMed Research International. ISSN 2314-6141. p. 1-7
2314-6141
10.1155/2014/814590
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Hindawi
publisher.none.fl_str_mv Hindawi
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv
repository.mail.fl_str_mv
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