“In situ” corneal and contact lens thickness changes with high resolution OCT
Autor(a) principal: | |
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Data de Publicação: | 2012 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/1822/13779 |
Resumo: | Purpose: To show the utility of high resolution spectral domain optical coherence tomography (HR SOCT) for the in situ evaluation of epithelial, stromal and contact lens (CL) thickness changes under closed-eye conditions without lens removal. Settings: Clinical and Experimental Optometry Research Lab, University of Minho, Portugal. Methods: Eight young healthy patients wore a thick soft CL during 90 minutes under closed-eye conditions and measures of epithelial and stromal corneal thickness were obtained at regular intervals using a HR SOCT (Copernicus HR, Optopol Tech. SA, Poland). Results: Minimal changes in epithelial thickness were detected with a transient statistically significant increase in epithelial thickness in the fellow control eye 30 minutes after insertion (p=0.028). A significant and progressive increase in stromal thickness up to 8% after 90 minutes of lens wear was observed at a constant rate of 2.5% 50 every 30 minutes, being statistically significant in all observations (p<0.001). Fellow control eye also showed a significant increase in stromal thickness at a much lower rate of 0.5% every 30 minutes. Lens thickness decreased significantly by 2% after 90 minutes of lens wear under closed eye conditions (p<0.001). Individual analysis showed that all eyes displayed stromal swelling, while only half of them showed epithelial swelling. Conclusion: Increase in stromal thickness and a slight decrease in lens thickness were observed in response to a hypoxic stimulus under closed eye conditions. High resolution spectral domain HR SOCT is a powerful tool to investigate in vivo the physiological interactions between cornea and contact lenses. |
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“In situ” corneal and contact lens thickness changes with high resolution OCTCoherence tomographyCorneaOCTstromal thicknessepithelial thicknessedemacontact lensesScience & TechnologyPurpose: To show the utility of high resolution spectral domain optical coherence tomography (HR SOCT) for the in situ evaluation of epithelial, stromal and contact lens (CL) thickness changes under closed-eye conditions without lens removal. Settings: Clinical and Experimental Optometry Research Lab, University of Minho, Portugal. Methods: Eight young healthy patients wore a thick soft CL during 90 minutes under closed-eye conditions and measures of epithelial and stromal corneal thickness were obtained at regular intervals using a HR SOCT (Copernicus HR, Optopol Tech. SA, Poland). Results: Minimal changes in epithelial thickness were detected with a transient statistically significant increase in epithelial thickness in the fellow control eye 30 minutes after insertion (p=0.028). A significant and progressive increase in stromal thickness up to 8% after 90 minutes of lens wear was observed at a constant rate of 2.5% 50 every 30 minutes, being statistically significant in all observations (p<0.001). Fellow control eye also showed a significant increase in stromal thickness at a much lower rate of 0.5% every 30 minutes. Lens thickness decreased significantly by 2% after 90 minutes of lens wear under closed eye conditions (p<0.001). Individual analysis showed that all eyes displayed stromal swelling, while only half of them showed epithelial swelling. Conclusion: Increase in stromal thickness and a slight decrease in lens thickness were observed in response to a hypoxic stimulus under closed eye conditions. High resolution spectral domain HR SOCT is a powerful tool to investigate in vivo the physiological interactions between cornea and contact lenses.Supported in part by research grants to A. Cervino from the Universitat de Valencia (UV-AE-20070225), the "Jose Castillejo" Research Grant from the Spanish Ministry of Science and Technology (JC2008-00078) and the Spanish Network for Research in Optometry (SAF2008-01114-E).Lippincott, Williams & WilkinsUniversidade do MinhoGonzález-Méijome, José ManuelCerviño, AlejandroPeixoto-de-Matos, S. C.Madrid-Costa, DavidJorge, JorgeFerrer-Blasco, Teresa20122012-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/13779eng0277-374010.1097/ICO.0b013e31823f090522240923http://journals.lww.com/corneajrnl/pages/default.aspxinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:51:18ZPortal AgregadorONG |
dc.title.none.fl_str_mv |
“In situ” corneal and contact lens thickness changes with high resolution OCT |
title |
“In situ” corneal and contact lens thickness changes with high resolution OCT |
spellingShingle |
“In situ” corneal and contact lens thickness changes with high resolution OCT González-Méijome, José Manuel Coherence tomography Cornea OCT stromal thickness epithelial thickness edema contact lenses Science & Technology |
title_short |
“In situ” corneal and contact lens thickness changes with high resolution OCT |
title_full |
“In situ” corneal and contact lens thickness changes with high resolution OCT |
title_fullStr |
“In situ” corneal and contact lens thickness changes with high resolution OCT |
title_full_unstemmed |
“In situ” corneal and contact lens thickness changes with high resolution OCT |
title_sort |
“In situ” corneal and contact lens thickness changes with high resolution OCT |
author |
González-Méijome, José Manuel |
author_facet |
González-Méijome, José Manuel Cerviño, Alejandro Peixoto-de-Matos, S. C. Madrid-Costa, David Jorge, Jorge Ferrer-Blasco, Teresa |
author_role |
author |
author2 |
Cerviño, Alejandro Peixoto-de-Matos, S. C. Madrid-Costa, David Jorge, Jorge Ferrer-Blasco, Teresa |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
Universidade do Minho |
dc.contributor.author.fl_str_mv |
González-Méijome, José Manuel Cerviño, Alejandro Peixoto-de-Matos, S. C. Madrid-Costa, David Jorge, Jorge Ferrer-Blasco, Teresa |
dc.subject.por.fl_str_mv |
Coherence tomography Cornea OCT stromal thickness epithelial thickness edema contact lenses Science & Technology |
topic |
Coherence tomography Cornea OCT stromal thickness epithelial thickness edema contact lenses Science & Technology |
description |
Purpose: To show the utility of high resolution spectral domain optical coherence tomography (HR SOCT) for the in situ evaluation of epithelial, stromal and contact lens (CL) thickness changes under closed-eye conditions without lens removal. Settings: Clinical and Experimental Optometry Research Lab, University of Minho, Portugal. Methods: Eight young healthy patients wore a thick soft CL during 90 minutes under closed-eye conditions and measures of epithelial and stromal corneal thickness were obtained at regular intervals using a HR SOCT (Copernicus HR, Optopol Tech. SA, Poland). Results: Minimal changes in epithelial thickness were detected with a transient statistically significant increase in epithelial thickness in the fellow control eye 30 minutes after insertion (p=0.028). A significant and progressive increase in stromal thickness up to 8% after 90 minutes of lens wear was observed at a constant rate of 2.5% 50 every 30 minutes, being statistically significant in all observations (p<0.001). Fellow control eye also showed a significant increase in stromal thickness at a much lower rate of 0.5% every 30 minutes. Lens thickness decreased significantly by 2% after 90 minutes of lens wear under closed eye conditions (p<0.001). Individual analysis showed that all eyes displayed stromal swelling, while only half of them showed epithelial swelling. Conclusion: Increase in stromal thickness and a slight decrease in lens thickness were observed in response to a hypoxic stimulus under closed eye conditions. High resolution spectral domain HR SOCT is a powerful tool to investigate in vivo the physiological interactions between cornea and contact lenses. |
publishDate |
2012 |
dc.date.none.fl_str_mv |
2012 2012-01-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/1822/13779 |
url |
http://hdl.handle.net/1822/13779 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
0277-3740 10.1097/ICO.0b013e31823f0905 22240923 http://journals.lww.com/corneajrnl/pages/default.aspx |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Lippincott, Williams & Wilkins |
publisher.none.fl_str_mv |
Lippincott, Williams & Wilkins |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
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repository.mail.fl_str_mv |
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1777303859900710912 |