Growth patterns, metabolic indicators and osteoarticular status in the Lusitano horse : a longitudinal study

Detalhes bibliográficos
Autor(a) principal: Fradinho, M.J.
Data de Publicação: 2019
Outros Autores: Mateus, Luisa, Bernardes, Nuno, Bessa, R.J.B., Caldeira, Rui M., Ferreira-Dias, Graça
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.5/21896
Resumo: Research Areas: Science & Technology - Other Topics
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spelling Growth patterns, metabolic indicators and osteoarticular status in the Lusitano horse : a longitudinal study3rd metacarpal bonedevelopmental orthopedic diseaseosteochondral conditions joccage-related-changesLusitano Horseparathyroid-hormonequantitative ultrasonographynoninvasive assessmentserum concentrationsskeletal metabolismResearch Areas: Science & Technology - Other TopicsDevelopment of a healthy musculoskeletal system is of high concern for horse breeders and users. A longitudinal field study was performed in order to: (i) evaluate growth patterns and long-term changes on bone quality, bone metabolism, growth factors and metabolic variables in the Lusitano horse; and (ii) retrospectively assess whether these changes were related with radiographic findings regarding osteochondrosis-like lesions (OC) at the onset of training. Thirty-four Lusitano foals born and raised at four stud-farms, were periodically weighed (BW), and measured (withers height-WH) from birth to 36 months of age. On the same days, blood samples were collected for determination of osteocalcin, bone alkaline phosphatase, insulin-like growth factor I (IGF-I), leptin, insulin, glucose, parathyroid hormone (PTH), calcium, phosphorus and magnesium plasma concentrations, and quantitative ultrasound measurements were performed on the right third metacarpal bone (McIII). At the end of the study horses underwent radiographic examination of the four fetlocks, hocks and stifles. According to their radiographic status (OC negative vs. OC positive), Richards growth function was adjusted to BW and WH data. Instantaneous BW and WH growth rates (BW IADG and WH IADG) were calculated for each foal, from the resolution of the first derivative of growth models for seven age-classes. The presence of radiographic findings compatible with OC at the onset of training was associated with changes in BW and WH growth rates. Positive horses presented higher BW IADG from six to 18 months of age and lower WH IADG before 45 days of age (P<0.001). Speed of sound measurements (SOS), bone markers, growth factors and other metabolic variables change markedly with age (P<0.01). OC positive horses tended to have lower SOS values at the lateral region of McIII, lower IGF-I, and higher insulin and PTH concentrations (P<0.1). This study provides indirect evidence that monitoring foals’ growth during the first year of life may be of assistance in managing the occurrence of OC. Further studies with a higher number of animals and a controlled feed intake should be pursued.Chris Rogers, Massey University, NEWZEALANDRepositório da Universidade de LisboaFradinho, M.J.Mateus, LuisaBernardes, NunoBessa, R.J.B.Caldeira, Rui M.Ferreira-Dias, Graça2021-09-21T22:57:18Z2019-07-172019-07-17T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.5/21896engFradinho MJ, Mateus L, Bernardes N, Bessa RJB, Caldeira RM, Ferreira-Dias G 2019. Growth patterns, metabolic indicators and osteoarticular status in the Lusitano horse : a longitudinal study. PLoSONE 14(7):e021990010.1371/journal.pone.02199001932-6203info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-03-06T14:51:27Zoai:www.repository.utl.pt:10400.5/21896Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T17:06:26.173040Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Growth patterns, metabolic indicators and osteoarticular status in the Lusitano horse : a longitudinal study
title Growth patterns, metabolic indicators and osteoarticular status in the Lusitano horse : a longitudinal study
spellingShingle Growth patterns, metabolic indicators and osteoarticular status in the Lusitano horse : a longitudinal study
Fradinho, M.J.
3rd metacarpal bone
developmental orthopedic disease
osteochondral conditions jocc
age-related-changes
Lusitano Horse
parathyroid-hormone
quantitative ultrasonography
noninvasive assessment
serum concentrations
skeletal metabolism
title_short Growth patterns, metabolic indicators and osteoarticular status in the Lusitano horse : a longitudinal study
title_full Growth patterns, metabolic indicators and osteoarticular status in the Lusitano horse : a longitudinal study
title_fullStr Growth patterns, metabolic indicators and osteoarticular status in the Lusitano horse : a longitudinal study
title_full_unstemmed Growth patterns, metabolic indicators and osteoarticular status in the Lusitano horse : a longitudinal study
title_sort Growth patterns, metabolic indicators and osteoarticular status in the Lusitano horse : a longitudinal study
author Fradinho, M.J.
author_facet Fradinho, M.J.
Mateus, Luisa
Bernardes, Nuno
Bessa, R.J.B.
Caldeira, Rui M.
Ferreira-Dias, Graça
author_role author
author2 Mateus, Luisa
Bernardes, Nuno
Bessa, R.J.B.
Caldeira, Rui M.
Ferreira-Dias, Graça
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório da Universidade de Lisboa
dc.contributor.author.fl_str_mv Fradinho, M.J.
Mateus, Luisa
Bernardes, Nuno
Bessa, R.J.B.
Caldeira, Rui M.
Ferreira-Dias, Graça
dc.subject.por.fl_str_mv 3rd metacarpal bone
developmental orthopedic disease
osteochondral conditions jocc
age-related-changes
Lusitano Horse
parathyroid-hormone
quantitative ultrasonography
noninvasive assessment
serum concentrations
skeletal metabolism
topic 3rd metacarpal bone
developmental orthopedic disease
osteochondral conditions jocc
age-related-changes
Lusitano Horse
parathyroid-hormone
quantitative ultrasonography
noninvasive assessment
serum concentrations
skeletal metabolism
description Research Areas: Science & Technology - Other Topics
publishDate 2019
dc.date.none.fl_str_mv 2019-07-17
2019-07-17T00:00:00Z
2021-09-21T22:57:18Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.5/21896
url http://hdl.handle.net/10400.5/21896
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Fradinho MJ, Mateus L, Bernardes N, Bessa RJB, Caldeira RM, Ferreira-Dias G 2019. Growth patterns, metabolic indicators and osteoarticular status in the Lusitano horse : a longitudinal study. PLoSONE 14(7):e0219900
10.1371/journal.pone.0219900
1932-6203
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Chris Rogers, Massey University, NEWZEALAND
publisher.none.fl_str_mv Chris Rogers, Massey University, NEWZEALAND
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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