Elementary and efficient catalyst process for the Knoevenagel condensation of araldehydes with arylmethylidene malononitrile

Detalhes bibliográficos
Autor(a) principal: Jlassi, Raja
Data de Publicação: 2018
Outros Autores: Da Costa Ribeiro, Ana Paula, Tiago, Gonçalo, Wang, Jiawei, Krawczyk, Marta S., Martins, Luisa, Naili, Houcine, Pombeiro, Armando, Rekik, Walid
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.21/8014
Resumo: A comparative study of the Knoevenagel condensation of an aromatic aldehyde with an active methylene compound (e.g., malononitrile or ethyl cyanoacetate), using solvent free grindstone conditions and microwave irradiation is reported. Our solvent free approaches led these reactions to proceed faster, more cleanly and in higher yields. Moreover, they also allowed the use of nitrobenzaldehydes, which failed to yield the desired products under traditional and water based approaches. Thus, an efficient procedure for the Knoevenagel condensation of aryl and heteroaromatic aldehydes with malononitrile. using the complex [CdNa2(mu-L-2)](n)center dot 6.34H(2)O or commercial CdO as catalyst under solvent-free and very mild conditions has been developed. (C) 2017 Elsevier B.V. All rights reserved.
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spelling Elementary and efficient catalyst process for the Knoevenagel condensation of araldehydes with arylmethylidene malononitrileKnoevenagel condensationGrindstone techniqueMicrowaveMalononitrileSolvent-free reactionA comparative study of the Knoevenagel condensation of an aromatic aldehyde with an active methylene compound (e.g., malononitrile or ethyl cyanoacetate), using solvent free grindstone conditions and microwave irradiation is reported. Our solvent free approaches led these reactions to proceed faster, more cleanly and in higher yields. Moreover, they also allowed the use of nitrobenzaldehydes, which failed to yield the desired products under traditional and water based approaches. Thus, an efficient procedure for the Knoevenagel condensation of aryl and heteroaromatic aldehydes with malononitrile. using the complex [CdNa2(mu-L-2)](n)center dot 6.34H(2)O or commercial CdO as catalyst under solvent-free and very mild conditions has been developed. (C) 2017 Elsevier B.V. All rights reserved.ElsevierRCIPLJlassi, RajaDa Costa Ribeiro, Ana PaulaTiago, GonçaloWang, JiaweiKrawczyk, Marta S.Martins, LuisaNaili, HoucinePombeiro, ArmandoRekik, Walid2018-02-01T12:33:42Z2018-02-242018-02-24T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.21/8014engJLASSI, Raja; [et al] – Elementary and efficient catalyst process for the Knoevenagel condensation of araldehydes with arylmethylidene malononitrile. Inorganica Chimica Acta. ISSN 0020-1693. Vol. 471 (2018), pp. 76-810020-169310.1016/j.ica.2017.10.028metadata only accessinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-08-03T09:54:51Zoai:repositorio.ipl.pt:10400.21/8014Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T20:16:51.438453Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Elementary and efficient catalyst process for the Knoevenagel condensation of araldehydes with arylmethylidene malononitrile
title Elementary and efficient catalyst process for the Knoevenagel condensation of araldehydes with arylmethylidene malononitrile
spellingShingle Elementary and efficient catalyst process for the Knoevenagel condensation of araldehydes with arylmethylidene malononitrile
Jlassi, Raja
Knoevenagel condensation
Grindstone technique
Microwave
Malononitrile
Solvent-free reaction
title_short Elementary and efficient catalyst process for the Knoevenagel condensation of araldehydes with arylmethylidene malononitrile
title_full Elementary and efficient catalyst process for the Knoevenagel condensation of araldehydes with arylmethylidene malononitrile
title_fullStr Elementary and efficient catalyst process for the Knoevenagel condensation of araldehydes with arylmethylidene malononitrile
title_full_unstemmed Elementary and efficient catalyst process for the Knoevenagel condensation of araldehydes with arylmethylidene malononitrile
title_sort Elementary and efficient catalyst process for the Knoevenagel condensation of araldehydes with arylmethylidene malononitrile
author Jlassi, Raja
author_facet Jlassi, Raja
Da Costa Ribeiro, Ana Paula
Tiago, Gonçalo
Wang, Jiawei
Krawczyk, Marta S.
Martins, Luisa
Naili, Houcine
Pombeiro, Armando
Rekik, Walid
author_role author
author2 Da Costa Ribeiro, Ana Paula
Tiago, Gonçalo
Wang, Jiawei
Krawczyk, Marta S.
Martins, Luisa
Naili, Houcine
Pombeiro, Armando
Rekik, Walid
author2_role author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv RCIPL
dc.contributor.author.fl_str_mv Jlassi, Raja
Da Costa Ribeiro, Ana Paula
Tiago, Gonçalo
Wang, Jiawei
Krawczyk, Marta S.
Martins, Luisa
Naili, Houcine
Pombeiro, Armando
Rekik, Walid
dc.subject.por.fl_str_mv Knoevenagel condensation
Grindstone technique
Microwave
Malononitrile
Solvent-free reaction
topic Knoevenagel condensation
Grindstone technique
Microwave
Malononitrile
Solvent-free reaction
description A comparative study of the Knoevenagel condensation of an aromatic aldehyde with an active methylene compound (e.g., malononitrile or ethyl cyanoacetate), using solvent free grindstone conditions and microwave irradiation is reported. Our solvent free approaches led these reactions to proceed faster, more cleanly and in higher yields. Moreover, they also allowed the use of nitrobenzaldehydes, which failed to yield the desired products under traditional and water based approaches. Thus, an efficient procedure for the Knoevenagel condensation of aryl and heteroaromatic aldehydes with malononitrile. using the complex [CdNa2(mu-L-2)](n)center dot 6.34H(2)O or commercial CdO as catalyst under solvent-free and very mild conditions has been developed. (C) 2017 Elsevier B.V. All rights reserved.
publishDate 2018
dc.date.none.fl_str_mv 2018-02-01T12:33:42Z
2018-02-24
2018-02-24T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.21/8014
url http://hdl.handle.net/10400.21/8014
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv JLASSI, Raja; [et al] – Elementary and efficient catalyst process for the Knoevenagel condensation of araldehydes with arylmethylidene malononitrile. Inorganica Chimica Acta. ISSN 0020-1693. Vol. 471 (2018), pp. 76-81
0020-1693
10.1016/j.ica.2017.10.028
dc.rights.driver.fl_str_mv metadata only access
info:eu-repo/semantics/openAccess
rights_invalid_str_mv metadata only access
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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