Cervical cancer in Cape Verde

Detalhes bibliográficos
Autor(a) principal: Vilares, Ana Teresa
Data de Publicação: 2022
Outros Autores: Ciabattoni, Riccardo, Cunha, Teresa Margarida, Félix, Ana
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/149624
Resumo: Funding Information: Publication costs for this article were supported by ecancer (UK Charity number 1176307). Publisher Copyright: © the authors; licensee ecancermedicalscience. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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spelling Cervical cancer in Cape Verdereappraisal upon referral to a tertiary cancer centreCape Verdecervical cancerepidemiologyHPV human papillomavirusrisk factorsOncologyCancer ResearchSDG 3 - Good Health and Well-beingFunding Information: Publication costs for this article were supported by ecancer (UK Charity number 1176307). Publisher Copyright: © the authors; licensee ecancermedicalscience. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.Background: Cervical cancer (CC) is the first cause of cancer-related deaths among Cape Verdean women. The absence of a national screening programme and a lack of dedicated cancer treatment facilities contribute to its high mortality rate. In an effort to improve the prognosis of these women, a health cooperation agreement was established between Portugal and Cape Verde (CV), allowing their evacuation to Portuguese hospitals. Our aim was to characterise CC among CV women, and to assess the response given to these patients in Instituto Português de Oncologia de Lisboa Francisco Gentil (IPOLFG), so that their treatment and follow-up protocols can be optimised and overall prognosis improved. Methods: Retrospective evaluation of women diagnosed with CC in CV that underwent therapy in IPOLFG between 2013 and 2020. Risk factors, demographic and tumour characteristics, treatment and outcomes were reviewed. Results: Fifty-eight patients were included. Squamous cell carcinoma was the most frequent (91.5%) histological type. HPV DNA was present in 25 out of 26 samples.The agreement rate between the pathology analysis performed in CV and in Portugal was high (87.9%); however, the agreement regarding the FIGO stage was low (15.5%). This may be explained by both the time interval between diagnosis and treatment (around 6 months) and by the absence of resources to accurately stage the disease in CV. In IPOLFG, 77.6% of patients received combined chemo-radiotherapy. Post-treatment follow-up varied widely, due to disease-related and bureaucratic issues. Eighteen patients developed cancer-related complications and/or cancer-related death. The survival rate and median overall survival (OS) in our cohort were of 89.7% and 73.2 months, respectively. Conclusions: Although most women had advanced-stage disease, the OS in our cohort was better than what has been reported for other African countries, probably because state-of-the-art treatment, frequently not accessible in those countries, was offered to all patients.NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)RUNVilares, Ana TeresaCiabattoni, RiccardoCunha, Teresa MargaridaFélix, Ana2023-02-23T22:21:06Z2022-112022-11-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10362/149624eng1754-6605PURE: 53992025https://doi.org/10.3332/ecancer.2022.1471info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:31:31Zoai:run.unl.pt:10362/149624Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:53:48.674925Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Cervical cancer in Cape Verde
reappraisal upon referral to a tertiary cancer centre
title Cervical cancer in Cape Verde
spellingShingle Cervical cancer in Cape Verde
Vilares, Ana Teresa
Cape Verde
cervical cancer
epidemiology
HPV human papillomavirus
risk factors
Oncology
Cancer Research
SDG 3 - Good Health and Well-being
title_short Cervical cancer in Cape Verde
title_full Cervical cancer in Cape Verde
title_fullStr Cervical cancer in Cape Verde
title_full_unstemmed Cervical cancer in Cape Verde
title_sort Cervical cancer in Cape Verde
author Vilares, Ana Teresa
author_facet Vilares, Ana Teresa
Ciabattoni, Riccardo
Cunha, Teresa Margarida
Félix, Ana
author_role author
author2 Ciabattoni, Riccardo
Cunha, Teresa Margarida
Félix, Ana
author2_role author
author
author
dc.contributor.none.fl_str_mv NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
RUN
dc.contributor.author.fl_str_mv Vilares, Ana Teresa
Ciabattoni, Riccardo
Cunha, Teresa Margarida
Félix, Ana
dc.subject.por.fl_str_mv Cape Verde
cervical cancer
epidemiology
HPV human papillomavirus
risk factors
Oncology
Cancer Research
SDG 3 - Good Health and Well-being
topic Cape Verde
cervical cancer
epidemiology
HPV human papillomavirus
risk factors
Oncology
Cancer Research
SDG 3 - Good Health and Well-being
description Funding Information: Publication costs for this article were supported by ecancer (UK Charity number 1176307). Publisher Copyright: © the authors; licensee ecancermedicalscience. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
publishDate 2022
dc.date.none.fl_str_mv 2022-11
2022-11-01T00:00:00Z
2023-02-23T22:21:06Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/149624
url http://hdl.handle.net/10362/149624
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 1754-6605
PURE: 53992025
https://doi.org/10.3332/ecancer.2022.1471
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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