Characterization of phenolic compounds in wild medicinal flowers from Portugal by HPLC-DAD-ESI/MS and evaluation of antifungal properties
Autor(a) principal: | |
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Data de Publicação: | 2013 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10198/8535 |
Resumo: | In the present work, the phenolic compounds of Castanea sativa, Filipendula ulmaria and Rosa micrantha flowers from Northeastern Portugal were characterized by HPLC-DAD-ESI/MS. Furthermore, it was performed a screening of their antifungal potential against Candida species (C. albicans, C. glabrata, C. parapsilosis and C. tropicalis). C. sativa sample gave the highest amount of phenolic compounds (18973 ± 40 µg/g, fw) and hydrolysable tannins (14873 ± 110 µg/g). The highest amounts of phenolic acids (569 ± 20 µg/g) and flavonoids (6090 ± 253 µg/g) were obtained in F. ulmaria and R. micrantha samples, respectively. Hydrolysable tannins (e.g. tri and digalloyl HHDP glucose) were the main group of phenolic compounds in C. sativa and F. ulmaria samples, while flavonoids (e.g. (+)-catechin and procyanidin dimers and trimers) were the most abundant group in R. micrantha. Thus, the stronger effect showed by this latter against all the Candida species (MIC ≤ 0.155 mg/mL) and, particularly its fungicide effects in C. glabrata, might be related to the mentioned flavonoids that were inexistence in the other samples. |
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Characterization of phenolic compounds in wild medicinal flowers from Portugal by HPLC-DAD-ESI/MS and evaluation of antifungal propertiesMedicinal flowersPhenolic compoundsHPLC-DAD-ESI/MSCandida speciesAntifungal effectIn the present work, the phenolic compounds of Castanea sativa, Filipendula ulmaria and Rosa micrantha flowers from Northeastern Portugal were characterized by HPLC-DAD-ESI/MS. Furthermore, it was performed a screening of their antifungal potential against Candida species (C. albicans, C. glabrata, C. parapsilosis and C. tropicalis). C. sativa sample gave the highest amount of phenolic compounds (18973 ± 40 µg/g, fw) and hydrolysable tannins (14873 ± 110 µg/g). The highest amounts of phenolic acids (569 ± 20 µg/g) and flavonoids (6090 ± 253 µg/g) were obtained in F. ulmaria and R. micrantha samples, respectively. Hydrolysable tannins (e.g. tri and digalloyl HHDP glucose) were the main group of phenolic compounds in C. sativa and F. ulmaria samples, while flavonoids (e.g. (+)-catechin and procyanidin dimers and trimers) were the most abundant group in R. micrantha. Thus, the stronger effect showed by this latter against all the Candida species (MIC ≤ 0.155 mg/mL) and, particularly its fungicide effects in C. glabrata, might be related to the mentioned flavonoids that were inexistence in the other samples.FCT, POPH-QREN and FSE for their grants (SFRH/BPD/4609/2008, SFRH/BD/72742/2010 and BPD/71076/2010, respectively). M. Dueñas thanks to the Programa Ramón y Cajal for a contract. The GIP-USAL is financially supported by the Spanish Ministerio de Ciencia e Innovación through the Consolider-Ingenio 2010 Programme (FUN-C-FOOD, CSD2007-00063), and Junta de Castilla y León (Grupo de Investigación de Excelencia, GR133).ElsevierBiblioteca Digital do IPBBarros, LillianAlves, Carlos TiagoDueñas, MontserratSilva, SóniaOliveira, RosárioCarvalho, Ana MariaHenriques, MarianaSantos-Buelga, CelestinoFerreira, Isabel C.F.R.2013-07-23T16:53:29Z20132013-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfapplication/pdfhttp://hdl.handle.net/10198/8535engBarros, Lillian; Alves, Carlos Tiago; Dueñas, Montserrat; Silva, Sónia; Oliveira, Rosário; Carvalho, Ana Maria; Henriques, Mariana; Santos-Buelga, Celestino; Ferreira, Isabel C.F.R. (2013). Characterization of phenolic compounds in wild medicinal flowers from Portugal by HPLC-DAD-ESI/MS and evaluation of antifungal properties. Industrial Crops and Products. ISSN 0926-6690. 44, p. 104–1100926-669010.1016/j.indcrop.2012.11.003info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-21T10:20:53Zoai:bibliotecadigital.ipb.pt:10198/8535Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T23:00:01.703562Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Characterization of phenolic compounds in wild medicinal flowers from Portugal by HPLC-DAD-ESI/MS and evaluation of antifungal properties |
title |
Characterization of phenolic compounds in wild medicinal flowers from Portugal by HPLC-DAD-ESI/MS and evaluation of antifungal properties |
spellingShingle |
Characterization of phenolic compounds in wild medicinal flowers from Portugal by HPLC-DAD-ESI/MS and evaluation of antifungal properties Barros, Lillian Medicinal flowers Phenolic compounds HPLC-DAD-ESI/MS Candida species Antifungal effect |
title_short |
Characterization of phenolic compounds in wild medicinal flowers from Portugal by HPLC-DAD-ESI/MS and evaluation of antifungal properties |
title_full |
Characterization of phenolic compounds in wild medicinal flowers from Portugal by HPLC-DAD-ESI/MS and evaluation of antifungal properties |
title_fullStr |
Characterization of phenolic compounds in wild medicinal flowers from Portugal by HPLC-DAD-ESI/MS and evaluation of antifungal properties |
title_full_unstemmed |
Characterization of phenolic compounds in wild medicinal flowers from Portugal by HPLC-DAD-ESI/MS and evaluation of antifungal properties |
title_sort |
Characterization of phenolic compounds in wild medicinal flowers from Portugal by HPLC-DAD-ESI/MS and evaluation of antifungal properties |
author |
Barros, Lillian |
author_facet |
Barros, Lillian Alves, Carlos Tiago Dueñas, Montserrat Silva, Sónia Oliveira, Rosário Carvalho, Ana Maria Henriques, Mariana Santos-Buelga, Celestino Ferreira, Isabel C.F.R. |
author_role |
author |
author2 |
Alves, Carlos Tiago Dueñas, Montserrat Silva, Sónia Oliveira, Rosário Carvalho, Ana Maria Henriques, Mariana Santos-Buelga, Celestino Ferreira, Isabel C.F.R. |
author2_role |
author author author author author author author author |
dc.contributor.none.fl_str_mv |
Biblioteca Digital do IPB |
dc.contributor.author.fl_str_mv |
Barros, Lillian Alves, Carlos Tiago Dueñas, Montserrat Silva, Sónia Oliveira, Rosário Carvalho, Ana Maria Henriques, Mariana Santos-Buelga, Celestino Ferreira, Isabel C.F.R. |
dc.subject.por.fl_str_mv |
Medicinal flowers Phenolic compounds HPLC-DAD-ESI/MS Candida species Antifungal effect |
topic |
Medicinal flowers Phenolic compounds HPLC-DAD-ESI/MS Candida species Antifungal effect |
description |
In the present work, the phenolic compounds of Castanea sativa, Filipendula ulmaria and Rosa micrantha flowers from Northeastern Portugal were characterized by HPLC-DAD-ESI/MS. Furthermore, it was performed a screening of their antifungal potential against Candida species (C. albicans, C. glabrata, C. parapsilosis and C. tropicalis). C. sativa sample gave the highest amount of phenolic compounds (18973 ± 40 µg/g, fw) and hydrolysable tannins (14873 ± 110 µg/g). The highest amounts of phenolic acids (569 ± 20 µg/g) and flavonoids (6090 ± 253 µg/g) were obtained in F. ulmaria and R. micrantha samples, respectively. Hydrolysable tannins (e.g. tri and digalloyl HHDP glucose) were the main group of phenolic compounds in C. sativa and F. ulmaria samples, while flavonoids (e.g. (+)-catechin and procyanidin dimers and trimers) were the most abundant group in R. micrantha. Thus, the stronger effect showed by this latter against all the Candida species (MIC ≤ 0.155 mg/mL) and, particularly its fungicide effects in C. glabrata, might be related to the mentioned flavonoids that were inexistence in the other samples. |
publishDate |
2013 |
dc.date.none.fl_str_mv |
2013-07-23T16:53:29Z 2013 2013-01-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10198/8535 |
url |
http://hdl.handle.net/10198/8535 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Barros, Lillian; Alves, Carlos Tiago; Dueñas, Montserrat; Silva, Sónia; Oliveira, Rosário; Carvalho, Ana Maria; Henriques, Mariana; Santos-Buelga, Celestino; Ferreira, Isabel C.F.R. (2013). Characterization of phenolic compounds in wild medicinal flowers from Portugal by HPLC-DAD-ESI/MS and evaluation of antifungal properties. Industrial Crops and Products. ISSN 0926-6690. 44, p. 104–110 0926-6690 10.1016/j.indcrop.2012.11.003 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Elsevier |
publisher.none.fl_str_mv |
Elsevier |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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